{"id":"https://openalex.org/W7220696565","doi":"https://doi.org/10.3389/fneur.2026.1919993","title":"The effect of FcRn inhibition on overlapping autoimmune comorbidity in AChR-seropositive generalized myasthenia gravis","display_name":"The effect of FcRn inhibition on overlapping autoimmune comorbidity in AChR-seropositive generalized myasthenia gravis","publication_year":2026,"publication_date":"2026-10-06","ids":{"openalex":"https://openalex.org/W7220696565","doi":"https://doi.org/10.3389/fneur.2026.1919993","pmid":"https://pubmed.ncbi.nlm.nih.gov/42903245","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13680258"},"language":"en","primary_location":{"id":"doi:10.3389/fneur.2026.1919993","doi":"https://doi.org/10.3389/fneur.2026.1919993","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fneur.2026.1919993","pdf_url":"https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2026.1919993/pdf","source":{"id":"https://openalex.org/S96975567","display_name":"Frontiers in Neurology","issn_l":"1664-2295","issn":["1664-2295"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neurology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2026.1919993/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079780570","display_name":"Vincenzo Di Stefano","orcid":"https://orcid.org/0000-0001-9805-1655","observed_orcids":["https://orcid.org/0000-0001-9805-1655"]},"institutions":[{"id":"https://openalex.org/I900890020","display_name":"University of Palermo","ror":"https://ror.org/044k9ta02","country_code":"IT","type":"education","lineage":["https://openalex.org/I900890020"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Vincenzo Di Stefano","raw_affiliation_strings":["Department of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo","institution_ids":["https://openalex.org/I900890020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092760448","display_name":"Nicasio Rini","orcid":"https://orcid.org/0009-0009-4435-5018","observed_orcids":["https://orcid.org/0009-0009-4435-5018"]},"institutions":[{"id":"https://openalex.org/I900890020","display_name":"University of Palermo","ror":"https://ror.org/044k9ta02","country_code":"IT","type":"education","lineage":["https://openalex.org/I900890020"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Nicasio Rini","raw_affiliation_strings":["Department of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo","institution_ids":["https://openalex.org/I900890020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5132699798","display_name":"Sofia Campo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I900890020","display_name":"University of Palermo","ror":"https://ror.org/044k9ta02","country_code":"IT","type":"education","lineage":["https://openalex.org/I900890020"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Sofia Campo","raw_affiliation_strings":["Department of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo","institution_ids":["https://openalex.org/I900890020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5157790054","display_name":"Flora D\u2019Amico","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I900890020","display_name":"University of Palermo","ror":"https://ror.org/044k9ta02","country_code":"IT","type":"education","lineage":["https://openalex.org/I900890020"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Flora D\u2019Amico","raw_affiliation_strings":["Department of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo","institution_ids":["https://openalex.org/I900890020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5157677791","display_name":"Aurora Meli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I900890020","display_name":"University of Palermo","ror":"https://ror.org/044k9ta02","country_code":"IT","type":"education","lineage":["https://openalex.org/I900890020"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Aurora Meli","raw_affiliation_strings":["Department of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo","institution_ids":["https://openalex.org/I900890020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021961840","display_name":"Simona Maccora","orcid":"https://orcid.org/0000-0002-3068-0356","observed_orcids":["https://orcid.org/0000-0002-3068-0356"]},"institutions":[{"id":"https://openalex.org/I900890020","display_name":"University of Palermo","ror":"https://ror.org/044k9ta02","country_code":"IT","type":"education","lineage":["https://openalex.org/I900890020"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Simona Maccora","raw_affiliation_strings":["Department of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo","institution_ids":["https://openalex.org/I900890020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046765579","display_name":"Filippo Brighina","orcid":"https://orcid.org/0000-0001-5875-3126","observed_orcids":["https://orcid.org/0000-0001-5875-3126"]},"institutions":[{"id":"https://openalex.org/I900890020","display_name":"University of Palermo","ror":"https://ror.org/044k9ta02","country_code":"IT","type":"education","lineage":["https://openalex.org/I900890020"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Filippo Brighina","raw_affiliation_strings":["Department of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo","institution_ids":["https://openalex.org/I900890020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113717503","display_name":"Liliana Bevilacqua","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134772","display_name":"AOU San Giovanni di Dio e Ruggi d'Aragona","ror":"https://ror.org/04etf9p48","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210134772"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Liliana Bevilacqua","raw_affiliation_strings":["Neurology Unit, Department of Medicine, Surgery and Dentistry \"Scuola Medica Salernitana, Neuroscience Section, University Hospital \u201cSan Giovanni di Dio e Ruggi d\u2019Aragona"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology Unit, Department of Medicine, Surgery and Dentistry \"Scuola Medica Salernitana, Neuroscience Section, University Hospital \u201cSan Giovanni di Dio e Ruggi d\u2019Aragona","institution_ids":["https://openalex.org/I4210134772"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005445227","display_name":"Paolo Barone","orcid":"https://orcid.org/0000-0001-8965-2504","observed_orcids":["https://orcid.org/0000-0001-8965-2504"]},"institutions":[{"id":"https://openalex.org/I4210134772","display_name":"AOU San Giovanni di Dio e Ruggi d'Aragona","ror":"https://ror.org/04etf9p48","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210134772"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Paolo Barone","raw_affiliation_strings":["IRCCS SYNLAB- SDN","Neurology Unit, Department of Medicine, Surgery and Dentistry \"Scuola Medica Salernitana, Neuroscience Section, University Hospital \u201cSan Giovanni di Dio e Ruggi d\u2019Aragona"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRCCS SYNLAB- SDN","institution_ids":["https://openalex.org/I4210153126"]},{"raw_affiliation_string":"Neurology Unit, Department of Medicine, Surgery and Dentistry \"Scuola Medica Salernitana, Neuroscience Section, University Hospital \u201cSan Giovanni di Dio e Ruggi d\u2019Aragona","institution_ids":["https://openalex.org/I4210134772"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079081429","display_name":"Alba Rosa Pati","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210103648","display_name":"Ospedale A. Perrino","ror":"https://ror.org/01ae87070","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210099368","https://openalex.org/I4210103648","https://openalex.org/I4210117053"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alba Rosa Pati","raw_affiliation_strings":["Neurology/Stroke Unit, Hospital A. Perrino"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology/Stroke Unit, Hospital A. Perrino","institution_ids":["https://openalex.org/I4210103648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036890382","display_name":"Mariangela Ferrara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210103648","display_name":"Ospedale A. Perrino","ror":"https://ror.org/01ae87070","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210099368","https://openalex.org/I4210103648","https://openalex.org/I4210117053"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Mariangela Ferrara","raw_affiliation_strings":["Neurology/Stroke Unit, Hospital A. Perrino"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology/Stroke Unit, Hospital A. Perrino","institution_ids":["https://openalex.org/I4210103648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105891373","display_name":"Augusto Maria Rini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210103648","display_name":"Ospedale A. Perrino","ror":"https://ror.org/01ae87070","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210099368","https://openalex.org/I4210103648","https://openalex.org/I4210117053"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Augusto Maria Rini","raw_affiliation_strings":["Neurology/Stroke Unit, Hospital A. Perrino"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology/Stroke Unit, Hospital A. Perrino","institution_ids":["https://openalex.org/I4210103648"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016602969","display_name":"Claudia Vinciguerra","orcid":"https://orcid.org/0000-0002-7646-7622","observed_orcids":["https://orcid.org/0000-0002-7646-7622"]},"institutions":[{"id":"https://openalex.org/I4210134772","display_name":"AOU San Giovanni di Dio e Ruggi d'Aragona","ror":"https://ror.org/04etf9p48","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210134772"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Claudia Vinciguerra","raw_affiliation_strings":["Neurology Unit, Department of Medicine, Surgery and Dentistry \"Scuola Medica Salernitana, Neuroscience Section, University Hospital \u201cSan Giovanni di Dio e Ruggi d\u2019Aragona"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology Unit, Department of Medicine, Surgery and Dentistry \"Scuola Medica Salernitana, Neuroscience Section, University Hospital \u201cSan Giovanni di Dio e Ruggi d\u2019Aragona","institution_ids":["https://openalex.org/I4210134772"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5079780570"],"corresponding_institution_ids":["https://openalex.org/I900890020"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.74776398,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"17","issue":null,"first_page":"1919993","last_page":"1919993"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11271","display_name":"Myasthenia Gravis and Thymoma","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11271","display_name":"Myasthenia Gravis and Thymoma","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11735","display_name":"Peripheral Neuropathies and Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11627","display_name":"Autoimmune Neurological Disorders and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/generalized-myasthenia-gravis","display_name":"generalized myasthenia gravis","score":0.972000002861023},{"id":"https://openalex.org/keywords/efgartigimod","display_name":"efgartigimod","score":0.871999979019165},{"id":"https://openalex.org/keywords/acetylcholine-receptor-antibodies","display_name":"acetylcholine receptor antibodies","score":0.8999999761581421},{"id":"https://openalex.org/keywords/stiff-person-syndrome","display_name":"stiff person syndrome","score":0.8519999980926514},{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":0.9419999718666077},{"id":"https://openalex.org/keywords/lambert-eaton-myasthenic-syndrome","display_name":"Lambert-Eaton myasthenic syndrome","score":0.9990000128746033},{"id":"https://openalex.org/keywords/prednisone-dose-reduction","display_name":"prednisone dose reduction","score":0.8270000219345093},{"id":"https://openalex.org/keywords/real-world-effectiveness","display_name":"real-world effectiveness","score":0.7620000243186951},{"id":"https://openalex.org/keywords/drug-safety","display_name":"drug safety","score":0.46399998664855957}],"concepts":[{"id":"https://openalex.org/C2778105408","wikidata":"https://www.wikidata.org/wiki/Q8285","display_name":"Myasthenia gravis","level":2,"score":0.8849999904632568},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.823199987411499},{"id":"https://openalex.org/C2778720950","wikidata":"https://www.wikidata.org/wiki/Q424972","display_name":"Prednisone","level":2,"score":0.8019999861717224},{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.6615999937057495},{"id":"https://openalex.org/C2908810637","wikidata":"https://www.wikidata.org/wiki/Q1797833","display_name":"Autoimmune diabetes","level":4,"score":0.5199000239372253},{"id":"https://openalex.org/C163764329","wikidata":"https://www.wikidata.org/wiki/Q785022","display_name":"Autoantibody","level":3,"score":0.5113999843597412},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4957999885082245},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.47620001435279846},{"id":"https://openalex.org/C2777240379","wikidata":"https://www.wikidata.org/wiki/Q776995","display_name":"Neuromuscular junction","level":2,"score":0.4059999883174896},{"id":"https://openalex.org/C2781232474","wikidata":"https://www.wikidata.org/wiki/Q124407","display_name":"Type 1 diabetes","level":3,"score":0.4052000045776367},{"id":"https://openalex.org/C2779901103","wikidata":"https://www.wikidata.org/wiki/Q419472","display_name":"Pyridostigmine","level":3,"score":0.3912999927997589},{"id":"https://openalex.org/C2779075594","wikidata":"https://www.wikidata.org/wiki/Q8084905","display_name":"Autoimmune disease","level":3,"score":0.38749998807907104},{"id":"https://openalex.org/C2778842783","wikidata":"https://www.wikidata.org/wiki/Q603502","display_name":"Plasmapheresis","level":3,"score":0.3799000084400177},{"id":"https://openalex.org/C2780130043","wikidata":"https://www.wikidata.org/wiki/Q192360","display_name":"Autoimmunity","level":3,"score":0.3709999918937683},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.36890000104904175},{"id":"https://openalex.org/C2776443654","wikidata":"https://www.wikidata.org/wiki/Q1235785","display_name":"Stiff person syndrome","level":4,"score":0.3352000117301941},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.32179999351501465},{"id":"https://openalex.org/C2779615886","wikidata":"https://www.wikidata.org/wiki/Q3090790","display_name":"Thymectomy","level":3,"score":0.2930999994277954},{"id":"https://openalex.org/C2780648854","wikidata":"https://www.wikidata.org/wiki/Q2745824","display_name":"Immunopathology","level":2,"score":0.2881999909877777},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.2718999981880188}],"mesh":[{"descriptor_ui":"D000203","descriptor_name":"Activities of Daily Living","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001323","descriptor_name":"Autoantibodies","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D001327","descriptor_name":"Autoimmune Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009157","descriptor_name":"Myasthenia Gravis","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D009157","descriptor_name":"Myasthenia Gravis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D009157","descriptor_name":"Myasthenia Gravis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009157","descriptor_name":"Myasthenia Gravis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D011950","descriptor_name":"Receptors, Cholinergic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D011961","descriptor_name":"Receptors, Fc","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D015395","descriptor_name":"Histocompatibility Antigens Class I","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015897","descriptor_name":"Comorbidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.3389/fneur.2026.1919993","doi":"https://doi.org/10.3389/fneur.2026.1919993","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fneur.2026.1919993","pdf_url":"https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2026.1919993/pdf","source":{"id":"https://openalex.org/S96975567","display_name":"Frontiers in Neurology","issn_l":"1664-2295","issn":["1664-2295"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neurology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13680258","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13680258/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13680258/pdf/fneur-17-1919993.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Neurol","raw_type":"Text"},{"id":"pmid:42903245","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42903245","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in neurology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:cb154c721dd146de8cad19bf9da7a7dc","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/cb154c721dd146de8cad19bf9da7a7dc","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Neurology, Vol 17 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fneur.2026.1919993","doi":"https://doi.org/10.3389/fneur.2026.1919993","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fneur.2026.1919993","pdf_url":"https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2026.1919993/pdf","source":{"id":"https://openalex.org/S96975567","display_name":"Frontiers in Neurology","issn_l":"1664-2295","issn":["1664-2295"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neurology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7220696565.pdf","grobid_xml":"https://content.openalex.org/works/W7220696565.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W1859891932","https://openalex.org/W2018956144","https://openalex.org/W2047570039","https://openalex.org/W2055492493","https://openalex.org/W2067350327","https://openalex.org/W2097591338","https://openalex.org/W2163243194","https://openalex.org/W2172887640","https://openalex.org/W2498470030","https://openalex.org/W2883123810","https://openalex.org/W2889615510","https://openalex.org/W2916599842","https://openalex.org/W2955629465","https://openalex.org/W3018402185","https://openalex.org/W3081922185","https://openalex.org/W3170470841","https://openalex.org/W3195527362","https://openalex.org/W3202951072","https://openalex.org/W3217302897","https://openalex.org/W4210246676","https://openalex.org/W4211188347","https://openalex.org/W4212956148","https://openalex.org/W4280545898","https://openalex.org/W4294845024","https://openalex.org/W4362458229","https://openalex.org/W4365457148","https://openalex.org/W4372214968","https://openalex.org/W4387143075","https://openalex.org/W4390953452","https://openalex.org/W4392057429","https://openalex.org/W4392380964","https://openalex.org/W4393162611","https://openalex.org/W4402119417","https://openalex.org/W4402643318","https://openalex.org/W4406545043","https://openalex.org/W4406716278","https://openalex.org/W4406751555","https://openalex.org/W4407317853","https://openalex.org/W4411192617","https://openalex.org/W4411278179","https://openalex.org/W4413682891","https://openalex.org/W4416347285","https://openalex.org/W4416723419","https://openalex.org/W7120209688","https://openalex.org/W7138971595","https://openalex.org/W7147172880"],"related_works":["https://openalex.org/W4410183935","https://openalex.org/W7147172880","https://openalex.org/W4386592488","https://openalex.org/W7163579352","https://openalex.org/W4412166647","https://openalex.org/W4408845926","https://openalex.org/W2944937742","https://openalex.org/W4390262348","https://openalex.org/W6967308790","https://openalex.org/W4379347576"],"abstract_inverted_index":{"Introduction:":[0],"Generalized":[1],"Myasthenia":[2,55,63],"gravis":[3],"(gMG)":[4],"is":[5,177],"a":[6,98,131,168,182],"rare":[7],"autoimmune":[8,42,79,142,175],"disorder":[9],"of":[10,34,58,138],"the":[11,21,29],"neuromuscular":[12],"junction":[13],"caused":[14],"by":[15],"IgG":[16],"autoantibodies":[17],"against":[18],"antigens":[19],"in":[20,37,103,127,134,146,186],"postsynaptic":[22],"cleft.":[23],"This":[24],"study":[25],"aimed":[26],"to":[27],"assess":[28],"real-world":[30],"effectiveness":[31],"and":[32,62,72,81,100,106,159],"safety":[33],"Efgartigimod":[35],"(EFG)":[36],"AChR-positive":[38,189],"gMG":[39,148,151,190],"with":[40,97,130,153,167,188,191],"overlapping":[41,192],"comorbidity.":[43],"Methods:":[44],"EFG":[45,166,180],"was":[46,114,125,144],"administered":[47,69],"as":[48],"4":[49,74,128],"consecutive":[50],"weekly":[51],"infusions":[52],"or":[53],"injections.":[54],"Gravis":[56,64],"Activity":[57],"Daily":[59],"Living":[60],"(MG-ADL)":[61],"quantitative":[65],"(QMG)":[66],"scales":[67],"were":[68,84],"at":[70],"baseline":[71],"after":[73],"weeks.":[75],"Clinical":[76],"data":[77],"on":[78,118,171],"comorbidities":[80],"prednisone":[82,136],"use":[83],"collected.":[85],"Results:":[86],"35":[87],"patients":[88,149,152,187],"(20":[89],"women,":[90],"mean":[91,132],"age":[92],"53.6":[93],"years)":[94],"received":[95],"EFG,":[96],"significant":[99],"clinical":[101,184],"improvement":[102],"both":[104],"MG-ADL":[105,109],"QMG":[107,119],"scores.":[108],"responder":[110],"rate":[111],"(MG-ADL":[112],"reduction\u22652)":[113],"79%,":[115],"while":[116],"68%":[117],"(QMG":[120],"reduction\u22653);":[121],"Minimal":[122],"symptoms":[123],"expression":[124],"reached":[126],"patients,":[129],"reduction":[133,170],"daily":[135],"dose":[137],"8":[139],"mg.":[140],"Overlapping":[141,174],"comorbidity":[143,176],"reported":[145],"12":[147],"(34%).":[150],"Stiff-Person":[154],"syndrome,":[155],"type":[156],"1":[157],"Diabetes":[158],"Lambert-Eaton":[160],"myasthenic":[161],"syndrome":[162],"benefited":[163],"more":[164],"from":[165],"higher":[169],"MG-ADL.":[172],"Conclusion:":[173],"not":[178],"rare.":[179],"demonstrated":[181],"meaningful":[183],"benefit":[185],"IgG-mediated":[193],"disorders.":[194]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-10-07T00:00:00"}