{"id":"https://openalex.org/W7220695072","doi":"https://doi.org/10.64898/2026.10.04.26364693","title":"Mifamurtide for Osteosarcoma in the United States: A Single-Center Real-World Experience","display_name":"Mifamurtide for Osteosarcoma in the United States: A Single-Center Real-World Experience","publication_year":2026,"publication_date":"2026-10-06","ids":{"openalex":"https://openalex.org/W7220695072","doi":"https://doi.org/10.64898/2026.10.04.26364693"},"language":"en","primary_location":{"id":"doi:10.64898/2026.10.04.26364693","doi":"https://doi.org/10.64898/2026.10.04.26364693","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.10.04.26364693","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/10/06/2026.10.04.26364693.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.medrxiv.org/content/medrxiv/early/2026/10/06/2026.10.04.26364693.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001610703","display_name":"Emily Kanaya Slotkin","orcid":"https://orcid.org/0000-0002-4463-5759","observed_orcids":["https://orcid.org/0000-0002-4463-5759"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Emily K Slotkin","raw_affiliation_strings":["Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":"https://orcid.org/0000-0002-4463-5759","affiliations":[{"raw_affiliation_string":"Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026131694","display_name":"Audrey Mauguen","orcid":"https://orcid.org/0000-0003-3236-6093","observed_orcids":["https://orcid.org/0000-0003-3236-6093"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Audrey Mauguen","raw_affiliation_strings":["Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015033268","display_name":"Jane Roach","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jane Roach","raw_affiliation_strings":["Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062320984","display_name":"Filemon S. Dela Cruz","orcid":"https://orcid.org/0000-0002-8356-5191","observed_orcids":["https://orcid.org/0000-0002-8356-5191"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Filemon S Dela Cruz","raw_affiliation_strings":["Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083758349","display_name":"Julia Glade Bender","orcid":"https://orcid.org/0000-0001-5316-6440","observed_orcids":["https://orcid.org/0000-0001-5316-6440"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julia L Glade Bender","raw_affiliation_strings":["Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083681305","display_name":"Michael Vincent Ortiz","orcid":"https://orcid.org/0000-0001-9379-314X","observed_orcids":["https://orcid.org/0000-0001-9379-314X"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael V Ortiz","raw_affiliation_strings":["Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042830355","display_name":"Jovana Pavisic","orcid":"https://orcid.org/0000-0002-6968-600X","observed_orcids":["https://orcid.org/0000-0002-6968-600X"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jovana Pavisic","raw_affiliation_strings":["Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074857673","display_name":"Olayode O. Babatunde","orcid":"https://orcid.org/0009-0007-7222-781X","observed_orcids":["https://orcid.org/0009-0007-7222-781X"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Olayode O Babatunde","raw_affiliation_strings":["Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024939030","display_name":"Lauren Baker Banks","orcid":"https://orcid.org/0000-0002-3443-6414","observed_orcids":["https://orcid.org/0000-0002-3443-6414"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lauren B Banks","raw_affiliation_strings":["Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027346244","display_name":"Ping Chi","orcid":"https://orcid.org/0000-0002-0159-5531","observed_orcids":["https://orcid.org/0000-0002-0159-5531"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ping Chi","raw_affiliation_strings":["Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089731384","display_name":"Sandra P. D\u2019Angelo","orcid":"https://orcid.org/0000-0002-3736-3783","observed_orcids":["https://orcid.org/0000-0002-3736-3783"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sandra P D\u2019Angelo","raw_affiliation_strings":["Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043833554","display_name":"Mark Andrew Dickson","orcid":"https://orcid.org/0000-0003-2764-751X","observed_orcids":["https://orcid.org/0000-0003-2764-751X"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark A Dickson","raw_affiliation_strings":["Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034595315","display_name":"Mrinal M. Gounder","orcid":"https://orcid.org/0000-0001-8468-0119","observed_orcids":["https://orcid.org/0000-0001-8468-0119"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mrinal M Gounder","raw_affiliation_strings":["Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078755190","display_name":"Ciara Marie Kelly","orcid":"https://orcid.org/0000-0002-4393-8088","observed_orcids":["https://orcid.org/0000-0002-4393-8088"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ciara M Kelly","raw_affiliation_strings":["Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067158281","display_name":"Mary Louise Keohan","orcid":"https://orcid.org/0000-0002-8240-4900","observed_orcids":["https://orcid.org/0000-0002-8240-4900"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary Lou Keohan","raw_affiliation_strings":["Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068677359","display_name":"Robert G. Maki","orcid":"https://orcid.org/0000-0002-9853-2528","observed_orcids":["https://orcid.org/0000-0002-9853-2528"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert G Maki","raw_affiliation_strings":["Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064214267","display_name":"Sujana Movva","orcid":"https://orcid.org/0000-0002-6569-6606","observed_orcids":["https://orcid.org/0000-0002-6569-6606"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sujana Movva","raw_affiliation_strings":["Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031037291","display_name":"William D. Tap","orcid":"https://orcid.org/0000-0001-7779-2796","observed_orcids":["https://orcid.org/0000-0001-7779-2796"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William D Tap","raw_affiliation_strings":["Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5128862198","display_name":"Laney Berman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laney Berman","raw_affiliation_strings":["Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5128905549","display_name":"Kleoniki Diamantis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kleoniki Diamantis","raw_affiliation_strings":["Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5128914825","display_name":"Jessie Hennessy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jessie Hennessy","raw_affiliation_strings":["Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5157687618","display_name":"Courtney Henelley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Courtney Henelley","raw_affiliation_strings":["Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017933159","display_name":"Paulette M. Kelly","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paulette Kelly","raw_affiliation_strings":["Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007471475","display_name":"Talia Sauerhaft","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Talia Sauerhaft","raw_affiliation_strings":["Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5128915332","display_name":"Jamie Voccola","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jamie Voccola","raw_affiliation_strings":["Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029966550","display_name":"Damon R. Reed","orcid":"https://orcid.org/0000-0002-8238-2465","observed_orcids":["https://orcid.org/0000-0002-8238-2465"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Damon R Reed","raw_affiliation_strings":["Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080725919","display_name":"Leonard H. Wexler","orcid":"https://orcid.org/0000-0003-0724-8263","observed_orcids":["https://orcid.org/0000-0003-0724-8263"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leonard H Wexler","raw_affiliation_strings":["Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010913859","display_name":"Paul A. Meyers","orcid":"https://orcid.org/0000-0001-6146-6101","observed_orcids":["https://orcid.org/0000-0001-6146-6101"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul A Meyers","raw_affiliation_strings":["Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics, Memorial Sloan Kettering Cancer Center (MSK), New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5001610703"],"corresponding_institution_ids":["https://openalex.org/I1334819555"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10975","display_name":"Bone Tumor Diagnosis and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mifamurtide","display_name":"mifamurtide","score":0.9929999709129333},{"id":"https://openalex.org/keywords/osteosarcoma","display_name":"osteosarcoma","score":0.9959999918937683},{"id":"https://openalex.org/keywords/expanded-access-program","display_name":"expanded access program","score":0.9039999842643738},{"id":"https://openalex.org/keywords/expanded-access","display_name":"compassionate use","score":0.9350000023841858},{"id":"https://openalex.org/keywords/metastatic-osteosarcoma","display_name":"metastatic osteosarcoma","score":0.8410000205039978},{"id":"https://openalex.org/keywords/relapsed-osteosarcoma","display_name":"relapsed osteosarcoma","score":0.9559999704360962},{"id":"https://openalex.org/keywords/progression-free-survival","display_name":"progression-free survival","score":0.8870000243186951},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9570000171661377},{"id":"https://openalex.org/keywords/adverse-events","display_name":"adverse events","score":0.6579999923706055},{"id":"https://openalex.org/keywords/antimicrobial-peptides","display_name":"antimicrobial peptides","score":0.5180000066757202},{"id":"https://openalex.org/keywords/drug-repurposing","display_name":"drug repurposing","score":0.49000000953674316}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9448999762535095},{"id":"https://openalex.org/C2777760704","wikidata":"https://www.wikidata.org/wiki/Q549534","display_name":"Osteosarcoma","level":2,"score":0.7815999984741211},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5769000053405762},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.5378000140190125},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5134999752044678},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.459199994802475},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4562999904155731},{"id":"https://openalex.org/C195910791","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Medical record","level":2,"score":0.44530001282691956},{"id":"https://openalex.org/C3019894029","wikidata":"https://www.wikidata.org/wiki/Q332823","display_name":"Overall survival","level":2,"score":0.42809998989105225},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.42669999599456787},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.39250001311302185},{"id":"https://openalex.org/C2778256501","wikidata":"https://www.wikidata.org/wiki/Q223911","display_name":"Sarcoma","level":2,"score":0.3749000132083893},{"id":"https://openalex.org/C2987315675","wikidata":"https://www.wikidata.org/wiki/Q1773974","display_name":"Disease control","level":2,"score":0.3433000147342682},{"id":"https://openalex.org/C503630168","wikidata":"https://www.wikidata.org/wiki/Q178069","display_name":"Necrosis","level":2,"score":0.33959999680519104},{"id":"https://openalex.org/C2908902254","wikidata":"https://www.wikidata.org/wiki/Q407954","display_name":"Compassionate Use","level":3,"score":0.3296999931335449},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.328000009059906},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.29760000109672546},{"id":"https://openalex.org/C2778822529","wikidata":"https://www.wikidata.org/wiki/Q1951525","display_name":"Progressive disease","level":3,"score":0.2703999876976013},{"id":"https://openalex.org/C2780073493","wikidata":"https://www.wikidata.org/wiki/Q7523837","display_name":"Single Center","level":2,"score":0.25}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.10.04.26364693","doi":"https://doi.org/10.64898/2026.10.04.26364693","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.10.04.26364693","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/10/06/2026.10.04.26364693.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.64898/2026.10.04.26364693","doi":"https://doi.org/10.64898/2026.10.04.26364693","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.10.04.26364693","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/10/06/2026.10.04.26364693.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7220695072.pdf","grobid_xml":"https://content.openalex.org/works/W7220695072.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2770031929","https://openalex.org/W2085365429","https://openalex.org/W2999901292","https://openalex.org/W2160996281","https://openalex.org/W4249829537","https://openalex.org/W3148873623","https://openalex.org/W3013816883","https://openalex.org/W2038927253","https://openalex.org/W4220752787","https://openalex.org/W2001291822"],"abstract_inverted_index":{"Abstract":[0],"Purpose":[1],"Mifamurtide":[2,80],"(liposomal":[3],"muramyl":[4],"tripeptide":[5],"phosphatidylethanolamine":[6],"[L-MTP-PE])":[7],"is":[8],"approved":[9],"in":[10,21],"many":[11],"countries":[12],"for":[13,18,61,88,95,105],"osteosarcoma":[14,35,67],"but":[15],"remains":[16],"unavailable":[17],"routine":[19],"use":[20,52],"the":[22,28,288],"United":[23],"States":[24],"(US).":[25],"We":[26],"describe":[27],"feasibility":[29],"and":[30,50,110,127,145,158,171,187,196,201,211,226,231,239,251,256,264,269,281,293],"outcomes":[31,298],"of":[32,178,287],"patients":[33,62,115,154,183,216,243],"with":[34,37,63,69,155,166,184,217],"treated":[36,68,190,220,244],"mifamurtide":[38,70,117,278],"at":[39,71,131,161,175,198,208,228,253,266],"Memorial":[40],"Sloan":[41],"Kettering":[42],"Cancer":[43],"Center":[44],"(MSK)":[45],"through":[46,75],"expanded":[47],"access":[48],"(EAP)":[49],"compassionate":[51],"(SPU)":[53],"pathways.":[54],"Methods":[55],"Medical":[56],"records":[57],"were":[58,99,137,299],"retrospectively":[59],"reviewed":[60],"completely":[64],"resected,":[65],"high-grade":[66],"MSK":[72],"from":[73],"2016\u20132026":[74],"EAP":[76],"or":[77,140],"SPU":[78],"protocols.":[79],"2":[81],"mg/m\u00b2":[82],"was":[83,193,206,223,236,248,261,279],"administered":[84],"intravenously":[85],"twice":[86],"weekly":[87,93],"12":[89],"weeks,":[90],"followed":[91],"by":[92,101],"administration":[94],"24":[96],"weeks.":[97],"Outcomes":[98],"evaluated":[100],"treatment":[102],"setting":[103],"and,":[104],"upfront":[106],"therapy,":[107],"metastatic":[108,129,218],"status":[109],"histologic":[111],"necrosis.":[112],"Results":[113],"Fifty-seven":[114],"received":[116],"(median":[118],"age,":[119],"14":[120],"years;":[121],"range,":[122],"2-60);":[123],"72%":[124],"had":[125,163],"localized":[126,156,185],"28%":[128],"disease":[130,157,186,219],"diagnosis.":[132],"No":[133],"serious":[134],"adverse":[135],"events":[136],"considered":[138],"possibly":[139],"probably":[141],"related":[142],"to":[143,283],"mifamurtide,":[144],"no":[146,164],"new":[147],"grade":[148],"3-4":[149],"safety":[150],"signals":[151],"emerged.":[152],"Five":[153],"\u226590%":[159],"necrosis":[160,189],"resection":[162],"events,":[165],"100%":[167],"progression-free":[168],"survival":[169,173,297],"(PFS)":[170],"overall":[172,296],"(OS)":[174],"median":[176],"follow-up":[177],"29":[179],"months.":[180,213,271],"Among":[181,214,241],"22":[182,242],"<90%":[188],"upfront,":[191,221],"PFS":[192,222,247],"82%,":[194],"66%,":[195],"59%":[197],"12,":[199,209,229,254,267],"24,":[200,210,230,255,268],"48":[202],"months,":[203,233,258],"respectively;":[204,234,259],"OS":[205,235,260],"95%":[207],"60":[212,270],"8":[215],"73%,":[224],"58%,":[225],"39%":[227],"36":[232,257],"100%,":[237],"86%,":[238],"86%.":[240],"after":[245],"relapse,":[246],"34%,":[249],"23%,":[250],"17%":[252],"91%,":[262],"70%,":[263],"35%":[265],"Conclusions":[272],"In":[273],"this":[274],"real-world":[275],"US":[276],"cohort,":[277],"feasible":[280],"safe":[282],"administer.":[284],"Despite":[285],"limitations":[286],"EAP/SPU":[289],"setting,":[290],"single-institution":[291],"administration,":[292],"patient":[294],"heterogeneity,":[295],"encouraging.":[300]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-10-07T00:00:00"}