{"id":"https://openalex.org/W7220409089","doi":"https://doi.org/10.1016/j.psj.2026.107891","title":"Restricted ovulator hens as a novel experimental model of fatty liver disease","display_name":"Restricted ovulator hens as a novel experimental model of fatty liver disease","publication_year":2026,"publication_date":"2026-10-05","ids":{"openalex":"https://openalex.org/W7220409089","doi":"https://doi.org/10.1016/j.psj.2026.107891","pmid":"https://pubmed.ncbi.nlm.nih.gov/42880091","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13694730"},"language":"en","primary_location":{"id":"doi:10.1016/j.psj.2026.107891","doi":"https://doi.org/10.1016/j.psj.2026.107891","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.psj.2026.107891","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0032579126015257/pdf","source":{"id":"https://openalex.org/S133896805","display_name":"Poultry Science","issn_l":"0032-5791","issn":["0032-5791","1525-3171"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Poultry Science","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.sciencedirect.com/science/article/pii/S0032579126015257/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074358895","display_name":"Daniel Junpyo Lee","orcid":"https://orcid.org/0000-0001-7224-3958","observed_orcids":["https://orcid.org/0000-0001-7224-3958"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]},{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["KR","US"],"is_corresponding":false,"raw_author_name":"Daniel Junpyo Lee","raw_affiliation_strings":["Department of Poultry Science, University of Georgia, Athens, GA, United States; Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Science, Seoul National University, Seoul, South Korea"],"raw_orcid":"https://orcid.org/0000-0001-7224-3958","affiliations":[{"raw_affiliation_string":"Department of Poultry Science, University of Georgia, Athens, GA, United States; Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Science, Seoul National University, Seoul, South Korea","institution_ids":["https://openalex.org/I139264467","https://openalex.org/I165733156"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5126572376","display_name":"Venkata Prathap Reddy Keshavareddy","orcid":"https://orcid.org/0009-0000-6729-4283","observed_orcids":["https://orcid.org/0009-0000-6729-4283"]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Venkata Prathap Reddy Keshavareddy","raw_affiliation_strings":["Department of Poultry Science, University of Georgia, Athens, GA, United States"],"raw_orcid":"https://orcid.org/0009-0000-6729-4283","affiliations":[{"raw_affiliation_string":"Department of Poultry Science, University of Georgia, Athens, GA, United States","institution_ids":["https://openalex.org/I165733156"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016887149","display_name":"Doyun Goo","orcid":"https://orcid.org/0000-0001-7373-2024","observed_orcids":["https://orcid.org/0000-0001-7373-2024"]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Doyun Goo","raw_affiliation_strings":["Department of Poultry Science, University of Georgia, Athens, GA, United States"],"raw_orcid":"https://orcid.org/0000-0001-7373-2024","affiliations":[{"raw_affiliation_string":"Department of Poultry Science, University of Georgia, Athens, GA, United States","institution_ids":["https://openalex.org/I165733156"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107056084","display_name":"Hemanth Reddy Katha","orcid":"https://orcid.org/0009-0005-0277-3853","observed_orcids":["https://orcid.org/0009-0005-0277-3853"]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hemanth Reddy Katha","raw_affiliation_strings":["Department of Poultry Science, University of Georgia, Athens, GA, United States"],"raw_orcid":"https://orcid.org/0009-0005-0277-3853","affiliations":[{"raw_affiliation_string":"Department of Poultry Science, University of Georgia, Athens, GA, United States","institution_ids":["https://openalex.org/I165733156"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092268029","display_name":"Venkata Sesha Reddy Choppa","orcid":"https://orcid.org/0000-0002-9528-8064","observed_orcids":["https://orcid.org/0000-0002-9528-8064"]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Venkata Sesha Reddy Choppa","raw_affiliation_strings":["Department of Poultry Science, University of Georgia, Athens, GA, United States"],"raw_orcid":"https://orcid.org/0000-0002-9528-8064","affiliations":[{"raw_affiliation_string":"Department of Poultry Science, University of Georgia, Athens, GA, United States","institution_ids":["https://openalex.org/I165733156"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5098404075","display_name":"Hamid Reza Rafieian-Naeini","orcid":"https://orcid.org/0009-0000-3319-273X","observed_orcids":["https://orcid.org/0009-0000-3319-273X"]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hamid Reza Rafieian Naeini","raw_affiliation_strings":["Department of Poultry Science, University of Georgia, Athens, GA, United States"],"raw_orcid":"https://orcid.org/0009-0000-3319-273X","affiliations":[{"raw_affiliation_string":"Department of Poultry Science, University of Georgia, Athens, GA, United States","institution_ids":["https://openalex.org/I165733156"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008036093","display_name":"Ishwari Gyawali","orcid":"https://orcid.org/0000-0003-1316-4795","observed_orcids":["https://orcid.org/0000-0003-1316-4795"]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ishwari Gyawali","raw_affiliation_strings":["Department of Poultry Science, University of Georgia, Athens, GA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Poultry Science, University of Georgia, Athens, GA, United States","institution_ids":["https://openalex.org/I165733156"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5120541744","display_name":"Sai Kumar Reddy Ragyari","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sai Kumar Reddy Ragyari","raw_affiliation_strings":["Department of Poultry Science, University of Georgia, Athens, GA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Poultry Science, University of Georgia, Athens, GA, United States","institution_ids":["https://openalex.org/I165733156"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014449052","display_name":"Deependra Paneru","orcid":"https://orcid.org/0000-0002-2780-3933","observed_orcids":["https://orcid.org/0000-0002-2780-3933"]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deependra Paneru","raw_affiliation_strings":["Department of Poultry Science, University of Georgia, Athens, GA, United States"],"raw_orcid":"https://orcid.org/0000-0002-2780-3933","affiliations":[{"raw_affiliation_string":"Department of Poultry Science, University of Georgia, Athens, GA, United States","institution_ids":["https://openalex.org/I165733156"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102881085","display_name":"Susan M. Williams","orcid":"https://orcid.org/0000-0003-3127-5384","observed_orcids":["https://orcid.org/0000-0003-3127-5384"]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan Michelle Williams","raw_affiliation_strings":["Department of Population Health, Poultry Diagnostic & Research Center, University of Georgia, Athens, GA, United States"],"raw_orcid":"https://orcid.org/0000-0003-3127-5384","affiliations":[{"raw_affiliation_string":"Department of Population Health, Poultry Diagnostic & Research Center, University of Georgia, Athens, GA, United States","institution_ids":["https://openalex.org/I165733156"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027621059","display_name":"Robert M. Gogal","orcid":"https://orcid.org/0000-0002-3213-4906","observed_orcids":["https://orcid.org/0000-0002-3213-4906"]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Michael Gogal","raw_affiliation_strings":["Department of Biomedical Sciences, University of Georgia, Athens, GA, United States"],"raw_orcid":"https://orcid.org/0000-0002-3213-4906","affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, University of Georgia, Athens, GA, United States","institution_ids":["https://openalex.org/I165733156"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133753030","display_name":"Younghoon Kim","orcid":"https://orcid.org/0000-0001-6769-0657","observed_orcids":["https://orcid.org/0000-0001-6769-0657"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Younghoon Kim","raw_affiliation_strings":["Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Science, Seoul National University, Seoul, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Science, Seoul National University, Seoul, South Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023243385","display_name":"Woo Kyun Kim","orcid":"https://orcid.org/0000-0002-0005-352X","observed_orcids":["https://orcid.org/0000-0002-0005-352X"]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Woo Kyun Kim","raw_affiliation_strings":["Department of Poultry Science, University of Georgia, Athens, GA, United States. Electronic address: wkkim@uga.edu"],"raw_orcid":"https://orcid.org/0000-0002-0005-352X","affiliations":[{"raw_affiliation_string":"Department of Poultry Science, University of Georgia, Athens, GA, United States. Electronic address: wkkim@uga.edu","institution_ids":["https://openalex.org/I165733156"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5023243385","https://openalex.org/A5133753030"],"corresponding_institution_ids":["https://openalex.org/I139264467","https://openalex.org/I165733156"],"apc_list":{"value":2600,"currency":"USD","value_usd":2600},"apc_paid":{"value":2600,"currency":"USD","value_usd":2600},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.78604901,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"105","issue":"12","first_page":"107891","last_page":"107891"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.8598999977111816,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.8598999977111816,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10152","display_name":"Animal Nutrition and Physiology","score":0.03669999912381172,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.02500000037252903,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatic-steatosis","display_name":"hepatic steatosis","score":0.9779999852180481},{"id":"https://openalex.org/keywords/laying-hens","display_name":"laying hens","score":0.9190000295639038},{"id":"https://openalex.org/keywords/hepatic-lipid-accumulation","display_name":"hepatic lipid accumulation","score":0.9660000205039978},{"id":"https://openalex.org/keywords/de-novo-lipogenesis","display_name":"de novo lipogenesis","score":0.8069999814033508},{"id":"https://openalex.org/keywords/triacylglycerol-biosynthesis","display_name":"triglyceride synthesis","score":0.9959999918937683},{"id":"https://openalex.org/keywords/high-cholesterol-diet","display_name":"high-cholesterol diet","score":0.9950000047683716},{"id":"https://openalex.org/keywords/hepatic-gene-expression","display_name":"hepatic gene expression","score":0.7149999737739563},{"id":"https://openalex.org/keywords/experimental-disease-models","display_name":"experimental disease models","score":0.6669999957084656},{"id":"https://openalex.org/keywords/egg-production","display_name":"egg production","score":0.6579999923706055}],"concepts":[{"id":"https://openalex.org/C141359234","wikidata":"https://www.wikidata.org/wiki/Q2734301","display_name":"Lipogenesis","level":3,"score":0.7875999808311462},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.7329999804496765},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.7193999886512756},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5983999967575073},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5957000255584717},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.5372999906539917},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4860999882221222},{"id":"https://openalex.org/C2776175330","wikidata":"https://www.wikidata.org/wiki/Q1365091","display_name":"Steatosis","level":2,"score":0.43860000371932983},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.41830000281333923},{"id":"https://openalex.org/C3018023364","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Significant difference","level":2,"score":0.3458000123500824},{"id":"https://openalex.org/C4733338","wikidata":"https://www.wikidata.org/wiki/Q2792936","display_name":"Lipid metabolism","level":2,"score":0.3456999957561493},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.34040001034736633},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.3328000009059906},{"id":"https://openalex.org/C2777075537","wikidata":"https://www.wikidata.org/wiki/Q929737","display_name":"Liver disease","level":2,"score":0.31209999322891235},{"id":"https://openalex.org/C2778117688","wikidata":"https://www.wikidata.org/wiki/Q264024","display_name":"Animal model","level":2,"score":0.3084999918937683},{"id":"https://openalex.org/C2992518758","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Fat accumulation","level":3,"score":0.30149999260902405},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.29679998755455017},{"id":"https://openalex.org/C139572402","wikidata":"https://www.wikidata.org/wiki/Q4927820","display_name":"Blood lipids","level":3,"score":0.29499998688697815},{"id":"https://openalex.org/C147583825","wikidata":"https://www.wikidata.org/wiki/Q620876","display_name":"Body weight","level":2,"score":0.29420000314712524},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.28369998931884766},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2831000089645386},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.2773999869823456},{"id":"https://openalex.org/C2992125399","wikidata":"https://www.wikidata.org/wiki/Q2824461","display_name":"Lipid accumulation","level":2,"score":0.2671000063419342},{"id":"https://openalex.org/C169222746","wikidata":"https://www.wikidata.org/wiki/Q4116558","display_name":"Factorial experiment","level":2,"score":0.2660999894142151},{"id":"https://openalex.org/C2778270857","wikidata":"https://www.wikidata.org/wiki/Q2723972","display_name":"Lipid profile","level":3,"score":0.2630999982357025},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.26159998774528503}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1016/j.psj.2026.107891","doi":"https://doi.org/10.1016/j.psj.2026.107891","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.psj.2026.107891","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0032579126015257/pdf","source":{"id":"https://openalex.org/S133896805","display_name":"Poultry Science","issn_l":"0032-5791","issn":["0032-5791","1525-3171"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Poultry Science","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13694730","doi":null,"is_oa":true,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42880091/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13694730/pdf/main.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Poult Sci","raw_type":"Text"},{"id":"pmid:42880091","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42880091","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Poultry science","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:a677ca9ad8f54f3eb59728d890b58bfd","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/a677ca9ad8f54f3eb59728d890b58bfd","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Poultry Science, Vol 105, Iss 12, Pp 107891- (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.psj.2026.107891","doi":"https://doi.org/10.1016/j.psj.2026.107891","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.psj.2026.107891","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0032579126015257/pdf","source":{"id":"https://openalex.org/S133896805","display_name":"Poultry Science","issn_l":"0032-5791","issn":["0032-5791","1525-3171"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Poultry Science","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6735000014305115,"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2"},{"score":0.5683000087738037,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7220409089.pdf","grobid_xml":"https://content.openalex.org/works/W7220409089.grobid-xml"},"referenced_works_count":32,"referenced_works":["https://openalex.org/W1194473706","https://openalex.org/W1542242159","https://openalex.org/W1758497516","https://openalex.org/W2059288647","https://openalex.org/W2062140428","https://openalex.org/W2071738437","https://openalex.org/W2115497342","https://openalex.org/W2138197806","https://openalex.org/W2149978324","https://openalex.org/W2151543526","https://openalex.org/W2164172053","https://openalex.org/W2286797029","https://openalex.org/W2296386264","https://openalex.org/W2743822989","https://openalex.org/W2810810993","https://openalex.org/W2915889811","https://openalex.org/W2945824290","https://openalex.org/W2979158257","https://openalex.org/W3108848204","https://openalex.org/W4311455437","https://openalex.org/W4387639161","https://openalex.org/W4389776064","https://openalex.org/W4391262685","https://openalex.org/W4402313914","https://openalex.org/W4402326933","https://openalex.org/W4405821106","https://openalex.org/W4408185507","https://openalex.org/W4408838719","https://openalex.org/W4409266683","https://openalex.org/W4416235127","https://openalex.org/W7155041446","https://openalex.org/W7171836585"],"related_works":["https://openalex.org/W3108848204","https://openalex.org/W3184832839","https://openalex.org/W3016560820","https://openalex.org/W4399515639","https://openalex.org/W2073608815","https://openalex.org/W4309370185","https://openalex.org/W7096171886","https://openalex.org/W2151543526","https://openalex.org/W2111930730","https://openalex.org/W2883250236"],"abstract_inverted_index":{"Fatty":[0],"liver":[1,150],"disease":[2],"(FLD)":[3],"is":[4,28],"a":[5,98,113,187,297,319],"common":[6],"metabolic":[7],"disorder":[8],"in":[9,75,112,155,159,198,213,243,252,277,284,324],"laying":[10,86,325],"hens,":[11,87,95],"characterized":[12],"by":[13,169,225],"excessive":[14],"hepatic":[15,63,261],"lipid":[16,64,143,262],"accumulation":[17,65,263],"and":[18,37,41,66,92,105,126,148,165,220,247,274,303],"reduced":[19],"egg":[20],"production.":[21],"The":[22,208],"development":[23],"of":[24,34,69,83,146,210,240,269,280,293],"reliable":[25],"experimental":[26,57,299],"models":[27],"essential":[29],"for":[30,38,59,109,301,317],"improving":[31],"the":[32,67,70,170,175,194,202,226,231,238,278,291],"understanding":[33],"FLD":[35,60,302,322],"pathogenesis":[36],"evaluating":[39],"preventive":[40],"therapeutic":[42],"strategies.":[43],"This":[44],"study":[45],"aimed":[46],"to":[47,310],"determine":[48],"whether":[49],"restricted":[50],"ovulator":[51],"(RO)":[52],"hens":[53,91,157,161,200,254,295,312],"represent":[54],"an":[55,307,314],"effective":[56,315],"model":[58,300],"based":[61],"on":[62],"severity":[68],"phenotype":[71,323],"under":[72],"dietary":[73],"challenge,":[74],"comparison":[76],"with":[77,174,193,230,256,266],"wild-type":[78],"(WT)":[79],"hens.":[80,258,286,326],"A":[81],"total":[82,142],"72":[84],"Hy-Line":[85],"including":[88],"36":[89,93],"WT":[90,160,257],"RO":[94,156,199,253,285,294,311],"were":[96,121],"fed":[97,201],"normal":[99],"(N),":[100],"low-choline":[101,104],"(L),":[102],"or":[103,129,177,233],"high-cholesterol":[106],"(LH)":[107],"diet":[108,172,191,204,228,309],"4":[110],"weeks":[111],"2":[114],"\u00d7":[115,190],"3":[116],"factorial":[117],"design.":[118],"All":[119],"data":[120],"analyzed":[122],"using":[123],"two-way":[124],"ANOVA,":[125],"Student's":[127],"t-test":[128],"Tukey's":[130],"honestly":[131],"significant":[132,188],"difference":[133],"test":[134],"was":[135,152,166,222,249,264],"applied":[136],"when":[137],"P":[138],"<":[139,163,181],"0.05.":[140],"Hepatic":[141,183],"content":[144],"(%":[145],"dry":[147],"wet":[149],"weight)":[151],"significantly":[153,223,250],"higher":[154],"than":[158],"(P":[162,180,205],"0.0001)":[164],"further":[167],"increased":[168,224],"LH":[171,203,227,308],"compared":[173,229,255],"N":[176,232],"L":[178,234],"diets":[179],"0.0001).":[182],"triglyceride":[184,244,281],"levels":[185,196],"exhibited":[186],"genotype":[189],"interaction,":[192],"highest":[195],"observed":[197],"=":[206],"0.02).":[207],"expression":[209,239,279],"genes":[211,241,273,283],"involved":[212,242],"de":[214,270],"novo":[215,271],"lipogenesis":[216],"(ACLY,":[217],"ACACA,":[218],"FASN,":[219],"SCD)":[221],"diet.":[235],"In":[236,259],"contrast,":[237],"synthesis":[245],"(GPAM":[246],"DGAT2)":[248],"elevated":[251],"conclusion,":[260],"associated":[265],"diet-induced":[267],"upregulation":[268],"lipogenesis-related":[272],"genotype-associated":[275],"increases":[276],"synthesis-related":[282],"Collectively,":[287],"these":[288],"findings":[289],"support":[290],"use":[292],"as":[296],"suitable":[298],"indicate":[304],"that":[305],"feeding":[306],"represents":[313],"approach":[316],"inducing":[318],"more":[320],"pronounced":[321]},"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2026-10-06T00:00:00"}