{"id":"https://openalex.org/W7220263444","doi":null,"title":"IMPROVING THE EFFECTIVENESS OF ENDOVASCULAR TREATMENT IN ACUTE ISCHEMIC STROKE: OPTIMIZED PATIENT SELECTION, REPERFUSION STRATEGY, AND POST-THROMBECTOMY MANAGEMENT.","display_name":"IMPROVING THE EFFECTIVENESS OF ENDOVASCULAR TREATMENT IN ACUTE ISCHEMIC STROKE: OPTIMIZED PATIENT SELECTION, REPERFUSION STRATEGY, AND POST-THROMBECTOMY MANAGEMENT.","publication_year":2026,"publication_date":"2026-09-01","ids":{"openalex":"https://openalex.org/W7220263444"},"language":"en","primary_location":{"id":"pmh:oai:ojs2.mrjedu.com:article/444","doi":null,"is_oa":true,"landing_page_url":"https://mrjedu.com/index.php/mrjedu/article/view/444","pdf_url":"https://mrjedu.com/index.php/mrjedu/article/download/444/305","source":{"id":"https://openalex.org/S7407075606","display_name":"MEDICAL RESEARCH JOURNAL","issn_l":"3060-5520","issn":["3060-5520"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nd","license_id":"https://openalex.org/licenses/cc-by-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"3060-5520","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://mrjedu.com/index.php/mrjedu/article/download/444/305","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5157101422","display_name":"Nematova Shakhlo Dadajon kizi Khamraeva Navruza Mahammadi kizi.","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Hamrayeva Navro'za Mahammadi qizi, Ne'matova Shahlo Dadajon qizi, Vahobova Dilafruz Ulmas qizi","raw_affiliation_strings":["Specialized Scientific and Practical Center of Neurosurgery and Neurorehabilitation at Samarkand State Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Specialized Scientific and Practical Center of Neurosurgery and Neurorehabilitation at Samarkand State Medical University","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5157101422"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10420","display_name":"Intracranial Aneurysms: Treatment and Complications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10816","display_name":"Cerebrovascular and Carotid Artery Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-ischemic-stroke","display_name":"acute ischemic stroke","score":0.8859999775886536},{"id":"https://openalex.org/keywords/mechanical-thrombectomy","display_name":"mechanical thrombectomy","score":0.953000009059906},{"id":"https://openalex.org/keywords/large-vessel-occlusion","display_name":"large vessel occlusion","score":0.9300000071525574},{"id":"https://openalex.org/keywords/patient-selection","display_name":"patient selection","score":0.972000002861023},{"id":"https://openalex.org/keywords/reperfusion-strategy","display_name":"reperfusion strategy","score":0.8379999995231628},{"id":"https://openalex.org/keywords/intravenous-thrombolysis","display_name":"intravenous thrombolysis","score":0.8069999814033508},{"id":"https://openalex.org/keywords/bridging-thrombolysis","display_name":"bridging thrombolysis","score":0.8450000286102295},{"id":"https://openalex.org/keywords/first-pass-reperfusion","display_name":"first-pass reperfusion","score":0.8270000219345093},{"id":"https://openalex.org/keywords/posterior-circulation-stroke","display_name":"posterior circulation stroke","score":0.8619999885559082},{"id":"https://openalex.org/keywords/basilar-artery-occlusion","display_name":"basilar artery occlusion","score":0.9900000095367432},{"id":"https://openalex.org/keywords/treatment-delay","display_name":"treatment delay","score":0.8119999766349792},{"id":"https://openalex.org/keywords/blood-pressure-control","display_name":"blood pressure control","score":0.7670000195503235},{"id":"https://openalex.org/keywords/symptomatic-intracranial-hemorrhage","display_name":"symptomatic intracranial hemorrhage","score":0.9480000138282776},{"id":"https://openalex.org/keywords/functional-outcome","display_name":"functional outcome","score":0.5230000019073486}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9799000024795532},{"id":"https://openalex.org/C3018386432","wikidata":"https://www.wikidata.org/wiki/Q426449","display_name":"Endovascular treatment","level":3,"score":0.8481000065803528},{"id":"https://openalex.org/C2779581417","wikidata":"https://www.wikidata.org/wiki/Q1931577","display_name":"Thrombolysis","level":3,"score":0.7897999882698059},{"id":"https://openalex.org/C2780931571","wikidata":"https://www.wikidata.org/wiki/Q568775","display_name":"Modified Rankin Scale","level":4,"score":0.6040999889373779},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.3837999999523163},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.38370001316070557},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.35429999232292175},{"id":"https://openalex.org/C3020199598","wikidata":"https://www.wikidata.org/wiki/Q12202","display_name":"Ischemic stroke","level":3,"score":0.3370000123977661},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.3118000030517578},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.29580000042915344},{"id":"https://openalex.org/C2776268601","wikidata":"https://www.wikidata.org/wiki/Q968808","display_name":"Occlusion","level":2,"score":0.29510000348091125},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.29330000281333923},{"id":"https://openalex.org/C3020166492","wikidata":"https://www.wikidata.org/wiki/Q12202","display_name":"Acute stroke","level":3,"score":0.2896000146865845},{"id":"https://openalex.org/C2778394091","wikidata":"https://www.wikidata.org/wiki/Q492482","display_name":"Posterior cerebral artery","level":4,"score":0.26980000734329224},{"id":"https://openalex.org/C2781012200","wikidata":"https://www.wikidata.org/wiki/Q500339","display_name":"Basilar artery","level":2,"score":0.2685999870300293},{"id":"https://openalex.org/C2780643987","wikidata":"https://www.wikidata.org/wiki/Q468414","display_name":"Angiography","level":2,"score":0.26429998874664307},{"id":"https://openalex.org/C2778820722","wikidata":"https://www.wikidata.org/wiki/Q4862390","display_name":"Brain ischemia","level":3,"score":0.25850000977516174},{"id":"https://openalex.org/C2775841333","wikidata":"https://www.wikidata.org/wiki/Q498179","display_name":"Middle cerebral artery","level":3,"score":0.2533999979496002},{"id":"https://openalex.org/C174348530","wikidata":"https://www.wikidata.org/wiki/Q188635","display_name":"Bridging (networking)","level":2,"score":0.25279998779296875},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.2526000142097473}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:ojs2.mrjedu.com:article/444","doi":null,"is_oa":true,"landing_page_url":"https://mrjedu.com/index.php/mrjedu/article/view/444","pdf_url":"https://mrjedu.com/index.php/mrjedu/article/download/444/305","source":{"id":"https://openalex.org/S7407075606","display_name":"MEDICAL RESEARCH JOURNAL","issn_l":"3060-5520","issn":["3060-5520"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nd","license_id":"https://openalex.org/licenses/cc-by-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"3060-5520","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:ojs2.mrjedu.com:article/444","doi":null,"is_oa":true,"landing_page_url":"https://mrjedu.com/index.php/mrjedu/article/view/444","pdf_url":"https://mrjedu.com/index.php/mrjedu/article/download/444/305","source":{"id":"https://openalex.org/S7407075606","display_name":"MEDICAL RESEARCH JOURNAL","issn_l":"3060-5520","issn":["3060-5520"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nd","license_id":"https://openalex.org/licenses/cc-by-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"3060-5520","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7220263444.pdf","grobid_xml":"https://content.openalex.org/works/W7220263444.grobid-xml"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W2119542322","https://openalex.org/W2139621750","https://openalex.org/W2171058244","https://openalex.org/W2277258071","https://openalex.org/W2526978419","https://openalex.org/W2767776410","https://openalex.org/W2787867590","https://openalex.org/W2791187944","https://openalex.org/W2802880180","https://openalex.org/W3023339300","https://openalex.org/W4210897413","https://openalex.org/W4304807965","https://openalex.org/W4304808118","https://openalex.org/W4319812352","https://openalex.org/W4319826361","https://openalex.org/W4386438989","https://openalex.org/W4386439171","https://openalex.org/W4387528022","https://openalex.org/W4410545596","https://openalex.org/W7125688844"],"related_works":["https://openalex.org/W4403890464","https://openalex.org/W4212795246","https://openalex.org/W7204519606","https://openalex.org/W4366241508","https://openalex.org/W2997574598","https://openalex.org/W4403476342","https://openalex.org/W1856203933","https://openalex.org/W7172384370","https://openalex.org/W4365479595","https://openalex.org/W2736624008"],"abstract_inverted_index":{"Background.":[0],"Endovascular":[1],"thrombectomy":[2,156],"has":[3],"fundamentally":[4],"changed":[5],"the":[6,44,48,65,153],"treatment":[7,50,69,82,115,167,245],"of":[8,24,46,67,103,116,155,195,212,219,235,249,271],"acute":[9,71,117],"ischemic":[10,72,118,173],"stroke":[11,119,198],"caused":[12],"by":[13],"large-vessel":[14],"occlusion.":[15],"Despite":[16],"technically":[17],"successful":[18,241],"reperfusion":[19,135,258],"in":[20,32,70,280],"a":[21,192,272],"substantial":[22],"proportion":[23],"treated":[25],"patients,":[26],"functional":[27],"independence":[28],"is":[29],"not":[30],"achieved":[31],"many":[33],"cases.":[34],"The":[35],"discrepancy":[36],"between":[37],"angiographic":[38],"success":[39],"and":[40,94,97,109,141,164,175,209,214,217,233,266],"clinical":[41,101,123,278],"recovery":[42],"emphasizes":[43],"importance":[45],"optimizing":[47],"entire":[49],"pathway":[51,275],"rather":[52],"than":[53],"focusing":[54],"exclusively":[55],"on":[56,129],"clot":[57],"retrieval.Objective.":[58],"To":[59],"analyze":[60],"contemporary":[61],"approaches":[62],"for":[63,207],"improving":[64],"effectiveness":[66,246],"endovascular":[68,114,187,244],"stroke,":[73,93],"with":[74,127,145,160,171,177],"particular":[75],"attention":[76],"to":[77],"patient":[78,255],"selection,":[79,256],"imaging":[80],"strategy,":[81],"time,":[83],"bridging":[84],"intravenous":[85,261],"thrombolysis,":[86,262],"first-pass":[87,220],"reperfusion,":[88],"large-core":[89],"infarction,":[90],"posterior":[91],"circulation":[92],"post-thrombectomy":[95,268],"management.Materials":[96],"Methods.":[98],"A":[99],"targeted":[100],"review":[102],"landmark":[104],"randomized":[105],"controlled":[106],"trials,":[107],"meta-analyses,":[108],"current":[110],"international":[111],"recommendations":[112],"concerning":[113],"was":[120],"performed.":[121],"Published":[122],"data":[124],"were":[125],"analyzed":[126],"emphasis":[128],"90-day":[130],"modified":[131],"Rankin":[132],"Scale":[133],"outcomes,":[134],"success,":[136],"symptomatic":[137],"intracranial":[138],"hemorrhage,":[139],"mortality,":[140],"procedural":[142],"factors":[143],"associated":[144],"favorable":[146],"neurological":[147],"recovery.Results.":[148],"Modern":[149],"evidence":[150,226],"demonstrates":[151],"that":[152],"benefit":[154,185],"extends":[157],"beyond":[158],"patients":[159,170,176],"small":[161],"infarct":[162],"cores":[163,174],"conventional":[165],"early":[166],"windows.":[168],"Selected":[169],"large":[172],"basilar":[178],"artery":[179],"occlusion":[180],"can":[181],"obtain":[182],"clinically":[183],"meaningful":[184],"from":[186],"treatment.":[188],"Treatment":[189],"delay":[190],"remains":[191],"major":[193],"determinant":[194],"outcome.":[196],"Effective":[197],"systems":[199],"therefore":[200],"require":[201],"rapid":[202,250],"vascular":[203],"imaging,":[204],"parallel":[205],"preparation":[206],"thrombolysis":[208],"thrombectomy,":[210],"minimization":[211],"door-to-puncture":[213],"puncture-to-reperfusion":[215],"intervals,":[216],"maximization":[218],"complete":[221],"or":[222],"near-complete":[223],"reperfusion.":[224],"Recent":[225],"also":[227],"supports":[228],"careful":[229],"post-procedural":[230],"hemodynamic":[231],"management":[232],"avoidance":[234],"excessively":[236],"intensive":[237],"blood-pressure":[238],"reduction":[239],"after":[240],"reperfusion.Conclusion.":[242],"Improving":[243],"requires":[247],"integration":[248],"diagnosis,":[251],"expanded":[252],"but":[253],"evidence-based":[254],"efficient":[257],"techniques,":[259],"appropriate":[260],"standardized":[263],"peri-procedural":[264],"management,":[265],"structured":[267],"care.":[269],"Implementation":[270],"unified":[273],"neurovascular":[274],"may":[276],"improve":[277],"outcomes":[279],"tertiary":[281],"neurosurgical":[282],"centers.":[283]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2026-10-05T00:00:00"}
