{"id":"https://openalex.org/W7220116675","doi":null,"title":"Aplicaci\u00f3n del p\u00e9ptido natriur\u00e9tico b en el diagn\u00f3stico de la miocardiopat\u00eda cirr\u00f3tica subcl\u00ednica.","display_name":"Aplicaci\u00f3n del p\u00e9ptido natriur\u00e9tico b en el diagn\u00f3stico de la miocardiopat\u00eda cirr\u00f3tica subcl\u00ednica.","publication_year":2025,"publication_date":"2025-01-10","ids":{"openalex":"https://openalex.org/W7220116675"},"language":"es","primary_location":{"id":"pmh:oai:revgastro.sld.cu:article/62","doi":null,"is_oa":true,"landing_page_url":"https://revgastro.sld.cu/index.php/gast/article/view/62","pdf_url":"https://revgastro.sld.cu/index.php/gast/article/download/62/201","source":{"id":"https://openalex.org/S7407076203","display_name":"Archivos Cubanos de Gastroenterolog\u00eda","issn_l":"2708-5538","issn":["2708-5538"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2708-5538","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://revgastro.sld.cu/index.php/gast/article/download/62/201","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034920484","display_name":"Teresita P\u00e9rez Gonz\u00e1lez","orcid":"https://orcid.org/0000-0003-0318-2914","observed_orcids":["https://orcid.org/0000-0003-0318-2914"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P\u00e9rez Gonz\u00e1lez, Teresita","raw_affiliation_strings":["Hospital General Docente \u201cIv\u00e1n Portuondo\u201d. San Antonio de los Ba\u00f1os. Artemisa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital General Docente \u201cIv\u00e1n Portuondo\u201d. San Antonio de los Ba\u00f1os. Artemisa","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102003066","display_name":"Marcia Samada Su\u00e1rez","orcid":"https://orcid.org/0000-0003-3795-3801","observed_orcids":["https://orcid.org/0000-0003-3795-3801"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Samada Su\u00e1rez, Marcia","raw_affiliation_strings":["Centro de Investigaciones M\u00e9dico Quir\u00fargicas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro de Investigaciones M\u00e9dico Quir\u00fargicas","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5153255587","display_name":"Aylen P\u00e9rez Barreda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210141954","display_name":"Instituto de Cardiolog\u00eda y Cirug\u00eda Cardiovascular","ror":"https://ror.org/050pxrb04","country_code":"CU","type":"healthcare","lineage":["https://openalex.org/I4210122314","https://openalex.org/I4210141954"]}],"countries":["CU"],"is_corresponding":false,"raw_author_name":"P\u00e9rez Barreda, Aylen","raw_affiliation_strings":["Instituto de Cardiolog\u00eda y Cirug\u00eda Cardiovascular"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Cardiolog\u00eda y Cirug\u00eda Cardiovascular","institution_ids":["https://openalex.org/I4210141954"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043658158","display_name":"Harlim Rodr\u00edguez Rodr\u00edguez","orcid":"https://orcid.org/0000-0003-3005-7107","observed_orcids":["https://orcid.org/0000-0003-3005-7107"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rodr\u00edguez Rodr\u00edguez, Harlim","raw_affiliation_strings":["Hospital General Docente \u201cIv\u00e1n Portuondo\u201d. San Antonio de los Ba\u00f1os. Artemisa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital General Docente \u201cIv\u00e1n Portuondo\u201d. San Antonio de los Ba\u00f1os. Artemisa","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024270398","display_name":"Zucel Danay Cruz Hern\u00e1ndez","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cruz Hern\u00e1ndez, Zucel Danay","raw_affiliation_strings":["Hospital General \"Leopoldito Mart\u00cdnez\". San Jos\u00e9 de las Lajas. Mayabeque"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital General \"Leopoldito Mart\u00cdnez\". San Jos\u00e9 de las Lajas. Mayabeque","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042915715","display_name":"Lisset Barroso M\u00e1rquez","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Barroso M\u00e1rquez, Lisset","raw_affiliation_strings":["Centro de Investigaciones M\u00e9dico Quir\u00fargicas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro de Investigaciones M\u00e9dico Quir\u00fargicas","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5157259413","display_name":"Lissette Chao Gonz\u00e1les","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chao Gonz\u00e1les, Lissette","raw_affiliation_strings":["Centro de Investigaciones M\u00e9dico Quir\u00fargicas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro de Investigaciones M\u00e9dico Quir\u00fargicas","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5154069189","display_name":"Yunia Tusen Toledo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tusen Toledo, Yunia","raw_affiliation_strings":["Centro de Investigaciones M\u00e9dico Quir\u00fargicas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro de Investigaciones M\u00e9dico Quir\u00fargicas","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nt-probnp","display_name":"NT-proBNP","score":0.9049999713897705},{"id":"https://openalex.org/keywords/brain-natriuretic-peptide","display_name":"brain natriuretic peptide","score":0.9419999718666077},{"id":"https://openalex.org/keywords/cirrhotic-cardiomyopathy","display_name":"cirrhotic cardiomyopathy","score":0.9049999713897705},{"id":"https://openalex.org/keywords/liver-cirrhosis","display_name":"liver cirrhosis","score":0.9169999957084656},{"id":"https://openalex.org/keywords/alcoholic-cirrhosis","display_name":"alcoholic cirrhosis","score":0.777999997138977},{"id":"https://openalex.org/keywords/diastolic-dysfunction","display_name":"diastolic dysfunction","score":0.878000020980835},{"id":"https://openalex.org/keywords/qtc-prolongation","display_name":"QTc prolongation","score":0.6830000281333923},{"id":"https://openalex.org/keywords/child-pugh-score","display_name":"Child-Pugh score","score":0.7689999938011169},{"id":"https://openalex.org/keywords/meld-score","display_name":"MELD score","score":0.9819999933242798},{"id":"https://openalex.org/keywords/cardiac-biomarkers","display_name":"cardiac biomarkers","score":0.7519999742507935},{"id":"https://openalex.org/keywords/subclinical-myocardial-dysfunction","display_name":"subclinical cardiac dysfunction","score":0.5540000200271606}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.49880000948905945},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.49779999256134033},{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.3041999936103821},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.23659999668598175},{"id":"https://openalex.org/C2986587452","wikidata":"https://www.wikidata.org/wiki/Q938438","display_name":"Statistical analysis","level":2,"score":0.1932000070810318},{"id":"https://openalex.org/C2985213535","wikidata":"https://www.wikidata.org/wiki/Q1626599","display_name":"Reference values","level":2,"score":0.15199999511241913},{"id":"https://openalex.org/C3018023364","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Significant difference","level":2,"score":0.1429000049829483},{"id":"https://openalex.org/C3019719930","wikidata":"https://www.wikidata.org/wiki/Q3910099","display_name":"Predictive value","level":2,"score":0.14229999482631683},{"id":"https://openalex.org/C3018541784","wikidata":"https://www.wikidata.org/wiki/Q5526318","display_name":"Gas analysis","level":2,"score":0.12370000034570694},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.12160000205039978}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:revgastro.sld.cu:article/62","doi":null,"is_oa":true,"landing_page_url":"https://revgastro.sld.cu/index.php/gast/article/view/62","pdf_url":"https://revgastro.sld.cu/index.php/gast/article/download/62/201","source":{"id":"https://openalex.org/S7407076203","display_name":"Archivos Cubanos de Gastroenterolog\u00eda","issn_l":"2708-5538","issn":["2708-5538"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2708-5538","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:revgastro.sld.cu:article/62","doi":null,"is_oa":true,"landing_page_url":"https://revgastro.sld.cu/index.php/gast/article/view/62","pdf_url":"https://revgastro.sld.cu/index.php/gast/article/download/62/201","source":{"id":"https://openalex.org/S7407076203","display_name":"Archivos Cubanos de Gastroenterolog\u00eda","issn_l":"2708-5538","issn":["2708-5538"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2708-5538","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7220116675.pdf","grobid_xml":"https://content.openalex.org/works/W7220116675.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W1978836206","https://openalex.org/W2018678968","https://openalex.org/W2021950130","https://openalex.org/W2025226178","https://openalex.org/W2027273540","https://openalex.org/W2032841932","https://openalex.org/W2124624517","https://openalex.org/W2136928735","https://openalex.org/W2564621871","https://openalex.org/W2611314696","https://openalex.org/W2802906787","https://openalex.org/W2891635818","https://openalex.org/W2911731064","https://openalex.org/W2913334744","https://openalex.org/W2963270505","https://openalex.org/W4205424910","https://openalex.org/W4255877789"],"related_works":["https://openalex.org/W7061118839","https://openalex.org/W2125588187","https://openalex.org/W3097262223","https://openalex.org/W2223405311","https://openalex.org/W2395430252","https://openalex.org/W2370090347","https://openalex.org/W2181407261","https://openalex.org/W2004017865","https://openalex.org/W4307867940","https://openalex.org/W2989760965"],"abstract_inverted_index":{"Introducci\u00f3n:":[0],"Existe":[1],"un":[2,84],"incremento":[3],"de":[4,27,29,33,42,46,58,66,76,83,87,91,107,111,126,138,168,173,186,201,217,226,229,244,247],"los":[5,43,89,174,202,227],"valores":[6],"del":[7,102,192],"p\u00e9ptido":[8],"natriur\u00e9tico":[9],"tipo":[10],"B":[11],"(PNB)":[12],"y":[13,32,93,116,134,213,220],"su":[14],"precursor":[15],"el":[16,74,81,117,120,131,161,165,221],"NH2":[17],"-terminal":[18],"proPNB":[19],"(NT-proPNB)":[20],"en":[21,48,69,73,80,171,184,199,207,232],"pacientes":[22,49,70,203,233],"cirr\u00f3ticos,":[23],"se":[24,53,95,123,188],"consideran":[25],"marcadores":[26],"gravedad":[28],"la":[30,40,56,112,135,154,169,190,210,218,245],"cirrosis":[31,51,113,155,219,235],"disfunci\u00f3n":[34,182],"cardiaca":[35],"subcl\u00ednica.":[36],"Objetivos:":[37],"Determinar":[38],"si":[39],"elevaci\u00f3n":[41,225],"niveles":[44,228],"plasm\u00e1ticos":[45],"NT-proPNB":[47,230],"con":[50,55,160,181,204,234],"hep\u00e1tica":[52],"relaciona":[54],"presencia":[57,246],"miocardiopat\u00eda":[59,211,248],"cirr\u00f3tica.":[60,249],"M\u00e9todos:":[61],"Se":[62],"realiz\u00f3":[63],"estudio":[64,103],"descriptivo,":[65],"corte":[67],"transversal,":[68],"cirr\u00f3ticos":[71],"atendidos":[72],"Centro":[75],"Investigaciones":[77],"M\u00e9dico":[78],"Quir\u00fargicas,":[79],"per\u00edodo":[82],"a\u00f1o.":[85],"Despu\u00e9s":[86],"aplicar":[88],"criterios":[90,105],"inclusi\u00f3n":[92],"exclusi\u00f3n":[94],"investigaron":[96],"60":[97],"casos.":[98],"Las":[99],"variables":[100,129],"principales":[101],"fueron:":[104],"diagn\u00f3sticos":[106],"miocardiopat\u00eda,":[108,179],"estadio":[109,166,215],"cl\u00ednico":[110],"por":[114],"Child-Pugh":[115],"MELD.":[118,222],"Para":[119],"procesamiento":[121],"estad\u00edstico":[122],"utilizaron":[124],"medidas":[125],"resumen":[127],"para":[128],"cualitativas,":[130],"chi":[132],"cuadrado":[133],"probabilidad":[136],"exacta":[137],"Fisher,":[139],"denotando":[140],"las":[141],"diferencias":[142],"como":[143],"significativas":[144],"cuando":[145],"p<":[146],"0,05.":[147],"Resultados:":[148],"La":[149,224],"etiolog\u00eda":[150],"m\u00e1s":[151],"frecuente":[152],"fue":[153,197],"alcoh\u00f3lica":[156],"(37%).":[157],"En":[158],"relaci\u00f3n":[159,205],"Child":[162],"Pugh":[163],"predomin\u00f3":[164],"descompensado":[167,216],"enfermedad":[170,238],"66.7%":[172],"pacientes,":[175],"38":[176],"(63,3%)":[177],"presentaron":[178],"todos":[180],"diast\u00f3lica,":[183],"34":[185],"ellos":[187],"asoci\u00f3":[189],"prolongaci\u00f3n":[191],"Qtc.":[193],"El":[194],"NT-pro":[195],"PNB":[196],"patol\u00f3gico":[198],"75%":[200],"significativa":[206],"cuanto":[208],"a":[209],"cirr\u00f3tica":[212],"al":[214],"Conclusiones:":[223],"plasm\u00e1tico":[231],"hep\u00e1tica,":[236],"sin":[237],"card\u00edaca":[239],"conocida,":[240],"pudiera":[241],"ser":[242],"indicativa":[243]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2026-10-05T00:00:00"}