{"id":"https://openalex.org/W7217437812","doi":null,"title":"EFFECTS OF ASCORBIC ACID AND SELENIUM SUPPLEMENTATION ON BASAL TESTOSTERONE CORTISOL RATIO IN MALE SPRAGUE DAWLEY RATS: Effects of Ascorbic and Selenium Supplementation","display_name":"EFFECTS OF ASCORBIC ACID AND SELENIUM SUPPLEMENTATION ON BASAL TESTOSTERONE CORTISOL RATIO IN MALE SPRAGUE DAWLEY RATS: Effects of Ascorbic and Selenium Supplementation","publication_year":2009,"publication_date":"2009-03-31","ids":{"openalex":"https://openalex.org/W7217437812"},"language":"en","primary_location":{"id":"pmh:oai:pafmj.org:article/1595","doi":null,"is_oa":true,"landing_page_url":"https://www.pafmj.org/PAFMJ/article/view/1595","pdf_url":"https://www.pafmj.org/PAFMJ/article/download/1595/1370","source":{"id":"https://openalex.org/S2739194844","display_name":"Pakistan Armed Forces Medical Journal","issn_l":"0030-9648","issn":["0030-9648","2411-8842"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319259","host_organization_name":"The Army Press","host_organization_lineage":["https://openalex.org/P4310319259"],"host_organization_lineage_names":["The Army Press"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"0030-9648","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.pafmj.org/PAFMJ/article/download/1595/1370","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061978703","display_name":"Ghulam Mustafa Lodhi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58993843","display_name":"Army Medical College","ror":"https://ror.org/03w0kj141","country_code":"PK","type":"education","lineage":["https://openalex.org/I58993843"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Lodhi, Ghulam Mustafa","raw_affiliation_strings":["Army Medical College Rawalpindi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Army Medical College Rawalpindi","institution_ids":["https://openalex.org/I58993843"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033974428","display_name":"Idrees Farooq Butt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58993843","display_name":"Army Medical College","ror":"https://ror.org/03w0kj141","country_code":"PK","type":"education","lineage":["https://openalex.org/I58993843"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Butt, Idrees Farooq","raw_affiliation_strings":["Army Medical College Rawalpindi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Army Medical College Rawalpindi","institution_ids":["https://openalex.org/I58993843"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101561826","display_name":"Muhammad Mazhar Hussain","orcid":"https://orcid.org/0000-0003-4860-2820","observed_orcids":["https://orcid.org/0000-0003-4860-2820"]},"institutions":[{"id":"https://openalex.org/I58993843","display_name":"Army Medical College","ror":"https://ror.org/03w0kj141","country_code":"PK","type":"education","lineage":["https://openalex.org/I58993843"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Hussain, Muhammad Mazhar","raw_affiliation_strings":["Army Medical College Rawalpindi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Army Medical College Rawalpindi","institution_ids":["https://openalex.org/I58993843"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5155781433","display_name":"Muhammad Aslam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58993843","display_name":"Army Medical College","ror":"https://ror.org/03w0kj141","country_code":"PK","type":"education","lineage":["https://openalex.org/I58993843"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Aslam, Muhammad","raw_affiliation_strings":["Army Medical College Rawalpindi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Army Medical College Rawalpindi","institution_ids":["https://openalex.org/I58993843"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I58993843"],"apc_list":{"value":7000,"currency":"PKR","value_usd":null},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.8320000171661377,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.8320000171661377,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11107","display_name":"Selenium in Biological Systems","score":0.08209999650716782,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":0.0333000011742115,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vitamin-c","display_name":"vitamin C","score":0.9769999980926514},{"id":"https://openalex.org/keywords/selenium","display_name":"selenium","score":0.7200000286102295},{"id":"https://openalex.org/keywords/testosterone","display_name":"testosterone","score":0.6000000238418579},{"id":"https://openalex.org/keywords/cortisol","display_name":"cortisol","score":0.984000027179718},{"id":"https://openalex.org/keywords/testosterone-cortisol-ratio","display_name":"testosterone/cortisol ratio","score":0.7749999761581421},{"id":"https://openalex.org/keywords/antioxidants","display_name":"antioxidants","score":0.597000002861023},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.8539999723434448},{"id":"https://openalex.org/keywords/malondialdehyde","display_name":"malondialdehyde","score":0.9980000257492065},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8209999799728394},{"id":"https://openalex.org/keywords/male-rats","display_name":"male rats","score":0.6110000014305115},{"id":"https://openalex.org/keywords/synergistic-supplementation","display_name":"synergistic supplementation","score":0.5590000152587891}],"concepts":[{"id":"https://openalex.org/C2986274086","wikidata":"https://www.wikidata.org/wiki/Q199678","display_name":"Ascorbic acid","level":2,"score":0.8812999725341797},{"id":"https://openalex.org/C2778401633","wikidata":"https://www.wikidata.org/wiki/Q418661","display_name":"Malondialdehyde","level":3,"score":0.8396000266075134},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.7784000039100647},{"id":"https://openalex.org/C553756173","wikidata":"https://www.wikidata.org/wiki/Q876","display_name":"Selenium","level":2,"score":0.7753999829292297},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7379000186920166},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6899999976158142},{"id":"https://openalex.org/C2780829032","wikidata":"https://www.wikidata.org/wiki/Q898539","display_name":"Lipid peroxidation","level":3,"score":0.6570000052452087},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6510999798774719},{"id":"https://openalex.org/C2778024521","wikidata":"https://www.wikidata.org/wiki/Q55639806","display_name":"Basal (medicine)","level":3,"score":0.635699987411499},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.37139999866485596},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.3086000084877014},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.2946000099182129}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:pafmj.org:article/1595","doi":null,"is_oa":true,"landing_page_url":"https://www.pafmj.org/PAFMJ/article/view/1595","pdf_url":"https://www.pafmj.org/PAFMJ/article/download/1595/1370","source":{"id":"https://openalex.org/S2739194844","display_name":"Pakistan Armed Forces Medical Journal","issn_l":"0030-9648","issn":["0030-9648","2411-8842"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319259","host_organization_name":"The Army Press","host_organization_lineage":["https://openalex.org/P4310319259"],"host_organization_lineage_names":["The Army Press"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"0030-9648","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:pafmj.org:article/1595","doi":null,"is_oa":true,"landing_page_url":"https://www.pafmj.org/PAFMJ/article/view/1595","pdf_url":"https://www.pafmj.org/PAFMJ/article/download/1595/1370","source":{"id":"https://openalex.org/S2739194844","display_name":"Pakistan Armed Forces Medical Journal","issn_l":"0030-9648","issn":["0030-9648","2411-8842"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319259","host_organization_name":"The Army Press","host_organization_lineage":["https://openalex.org/P4310319259"],"host_organization_lineage_names":["The Army Press"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"0030-9648","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322799","display_name":"Higher Education Commission, Pakistan","ror":"https://ror.org/038y3sz68"},{"id":"https://openalex.org/F4320324282","display_name":"National University of Sciences and Technology","ror":"https://ror.org/03w2j5y17"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7217437812.pdf","grobid_xml":"https://content.openalex.org/works/W7217437812.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7169483029","https://openalex.org/W2187798050","https://openalex.org/W6969005315","https://openalex.org/W1993909890","https://openalex.org/W1996853597","https://openalex.org/W2890257132","https://openalex.org/W72353010","https://openalex.org/W2181323333","https://openalex.org/W2137351911","https://openalex.org/W2894000328"],"abstract_inverted_index":{"Objective:":[0],"To":[1],"determine":[2],"the":[3,34],"effects":[4,162],"of":[5,26,36,47,143,163,183],"ascorbic":[6,144,164],"acid":[7,145,165],"and":[8,24,56,74,94,99,103,114,146,166,181],"selenium":[9,147,167],"supplementation":[10,78],"on":[11,110],"basal":[12],"testosterone":[13,98,129,152,184],"cortisol":[14,100,130,153,185],"ratio":[15,131,154,186],"in":[16,33,42,71,128,132,151,158,171,174],"male":[17,59],"Sprague":[18,60],"Dawley":[19,61],"rats.Design:":[20],"Quasi":[21],"experimental":[22],"study.Place":[23],"Duration":[25],"Study:":[27],"The":[28],"study":[29],"was":[30,120,124],"carried":[31],"out":[32],"department":[35],"Physiology,":[37],"Army":[38],"Medical":[39],"College":[40],"Rawalpindi":[41],"collaboration":[43],"with":[44,68,82,135,141,155],"National":[45],"Institute":[46],"Health,":[48],"Islamabad":[49],"during":[50],"October":[51],"2006":[52],"to":[53],"September":[54],"2007.Materials":[55],"Methods:":[57],"Forty":[58],"rats":[62,70,133,139],"were":[63,79,92,108],"divided":[64],"into":[65],"four":[66],"groups":[67],"ten":[69],"each":[72],"group":[73],"above":[75],"mentioned":[76],"antioxidants":[77],"given":[80],"along":[81],"standard":[83],"diet":[84],"for":[85,96],"one":[86],"month.":[87],"After":[88],"this,":[89],"blood":[90],"samples":[91],"taken":[93],"analyzed":[95,109],"serum":[97],"by":[101],"ELISA":[102],"malondialdehyde":[104,159],"levels":[105],"colorimetrically.":[106],"Results":[107],"SPSS":[111],"version":[112],"13":[113],"p":[115],"value":[116],"less":[117],"than":[118],"0.05":[119],"considered":[121],"significant.Results:":[122],"There":[123],"no":[125],"significant":[126,149],"rise":[127,150,182],"supplemented":[134,140],"single":[136],"antioxidant,":[137],"however":[138],"combination":[142],"revealed":[148],"a":[156,172],"fall":[157],"levels.Conclusions:":[160],"Synergistic":[161],"may":[168],"have":[169],"resulted":[170],"decline":[173],"reactive":[175],"oxygen":[176],"species":[177],"induced":[178],"lipid":[179],"peroxidation":[180]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-10-03T00:00:00"}