{"id":"https://openalex.org/W7216722305","doi":null,"title":"Charting features and dynamics of residual colorectal tumors surviving EGFR blockade","display_name":"Charting features and dynamics of residual colorectal tumors surviving EGFR blockade","publication_year":null,"publication_date":null,"ids":{"openalex":"https://openalex.org/W7216722305"},"language":"en","primary_location":{"id":"pmh:oai:iris.unito.it:2318/2016993","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2318/2016993","pdf_url":"https://iris.unito.it/bitstream/2318/2016993/2/PhD%20Thesis_Irene%20Catalano.pdf","source":{"id":"https://openalex.org/S4306400637","display_name":"Institutional Research Information System University of Turin (University of Turin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I55143463","host_organization_name":"University of Turin","host_organization_lineage":["https://openalex.org/I55143463"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://iris.unito.it/bitstream/2318/2016993/2/PhD%20Thesis_Irene%20Catalano.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023997731","display_name":"Irene Catalano","orcid":"https://orcid.org/0000-0002-3895-5860","observed_orcids":["https://orcid.org/0000-0002-3895-5860"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"CATALANO, IRENE","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5023997731"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10417","display_name":"Lung Cancer Treatments and Mutations","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.9039999842643738},{"id":"https://openalex.org/keywords/egfr-inhibition","display_name":"EGFR inhibition","score":0.8930000066757202},{"id":"https://openalex.org/keywords/residual-tumor","display_name":"residual tumor","score":0.5950000286102295},{"id":"https://openalex.org/keywords/tumor-dynamics","display_name":"tumor dynamics","score":0.7770000100135803},{"id":"https://openalex.org/keywords/tumor-growth-kinetics","display_name":"tumor growth kinetics","score":0.3400000035762787},{"id":"https://openalex.org/keywords/egfr-inhibitors","display_name":"EGFR inhibitors","score":0.5230000019073486}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6538000106811523},{"id":"https://openalex.org/C2778468042","wikidata":"https://www.wikidata.org/wiki/Q273976","display_name":"Blockade","level":3,"score":0.5634999871253967},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.43050000071525574},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.4092000126838684},{"id":"https://openalex.org/C155512373","wikidata":"https://www.wikidata.org/wiki/Q287450","display_name":"Residual","level":2,"score":0.35580000281333923},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3529999852180481},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.33739998936653137},{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.3019999861717224},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2644999921321869},{"id":"https://openalex.org/C2779438470","wikidata":"https://www.wikidata.org/wiki/Q424401","display_name":"Epidermal growth factor receptor","level":3,"score":0.26269999146461487}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:iris.unito.it:2318/2016993","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2318/2016993","pdf_url":"https://iris.unito.it/bitstream/2318/2016993/2/PhD%20Thesis_Irene%20Catalano.pdf","source":{"id":"https://openalex.org/S4306400637","display_name":"Institutional Research Information System University of Turin (University of Turin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I55143463","host_organization_name":"University of Turin","host_organization_lineage":["https://openalex.org/I55143463"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"}],"best_oa_location":{"id":"pmh:oai:iris.unito.it:2318/2016993","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2318/2016993","pdf_url":"https://iris.unito.it/bitstream/2318/2016993/2/PhD%20Thesis_Irene%20Catalano.pdf","source":{"id":"https://openalex.org/S4306400637","display_name":"Institutional Research Information System University of Turin (University of Turin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I55143463","host_organization_name":"University of Turin","host_organization_lineage":["https://openalex.org/I55143463"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7216722305.pdf","grobid_xml":"https://content.openalex.org/works/W7216722305.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3046925633","https://openalex.org/W2577591608","https://openalex.org/W2891464997","https://openalex.org/W2902728680","https://openalex.org/W7167652314","https://openalex.org/W2962240118","https://openalex.org/W2314661437","https://openalex.org/W1914351667","https://openalex.org/W4252166005","https://openalex.org/W4391035959"],"abstract_inverted_index":{"Residual":[0],"colorectal":[1],"tumors":[2],"after":[3,19],"EGFR":[4],"blockade":[5],"are":[6],"made":[7],"of":[8],"slowly":[9],"cycling":[10],"cells":[11],"that":[12],"regain":[13],"proliferative":[14],"capacities":[15],"and":[16],"drug":[17],"sensitivity":[18],"a":[20],"washout":[21],"period":[22],"....":[23]},"counts_by_year":[],"updated_date":"2026-10-17T09:40:24.721904","created_date":"2026-10-03T00:00:00"}