{"id":"https://openalex.org/W7216625994","doi":null,"title":"Antidiabetic potentiality of aqueous leaf extract of Leucas zeylanica in alloxan-induced diabetic rats","display_name":"Antidiabetic potentiality of aqueous leaf extract of Leucas zeylanica in alloxan-induced diabetic rats","publication_year":2016,"publication_date":"2016-10-05","ids":{"openalex":"https://openalex.org/W7216625994"},"language":"en","primary_location":{"id":"pmh:oai:ojs2.jipbs.com:article/198","doi":null,"is_oa":true,"landing_page_url":"https://jipbs.com/index.php/journal/article/view/198","pdf_url":"https://jipbs.com/index.php/journal/article/download/198/173","source":{"id":"https://openalex.org/S4387283359","display_name":"Journal of Innovations in Pharmaceutical and Biological Sciences","issn_l":"2349-2759","issn":["2349-2759","2395-1095"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2395-1095","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://jipbs.com/index.php/journal/article/download/198/173","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041196363","display_name":"Mycal Dutta","orcid":"https://orcid.org/0000-0001-5779-0523","observed_orcids":["https://orcid.org/0000-0001-5779-0523","https://orcid.org/0009-0008-0373-4153"]},"institutions":[{"id":"https://openalex.org/I3132920206","display_name":"BGC Trust University Bangladesh","ror":"https://ror.org/05s2ecw65","country_code":"BD","type":"education","lineage":["https://openalex.org/I3132920206"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Mycal Dutta","raw_affiliation_strings":["Assistant Professor, Department of Pharmacy, BGC Trust University Bangladesh, BGC Biddyanagar, Chandanaish, Chittagong, Bangladesh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Assistant Professor, Department of Pharmacy, BGC Trust University Bangladesh, BGC Biddyanagar, Chandanaish, Chittagong, Bangladesh","institution_ids":["https://openalex.org/I3132920206"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111005006","display_name":"Md. Waseque Mia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I133190216","display_name":"Shahjalal University of Science and Technology","ror":"https://ror.org/05hm0vv72","country_code":"BD","type":"education","lineage":["https://openalex.org/I133190216"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Md. Waseque Mia","raw_affiliation_strings":["Lecturer, Department of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, Bangladesh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lecturer, Department of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, Bangladesh","institution_ids":["https://openalex.org/I133190216"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103029956","display_name":"Md. Zia Uddin","orcid":"https://orcid.org/0000-0002-0606-0966","observed_orcids":["https://orcid.org/0000-0002-0606-0966"]},"institutions":[{"id":"https://openalex.org/I3132920206","display_name":"BGC Trust University Bangladesh","ror":"https://ror.org/05s2ecw65","country_code":"BD","type":"education","lineage":["https://openalex.org/I3132920206"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Md. Zia Uddin","raw_affiliation_strings":["Assistant Professor, Department of Pharmacy, BGC Trust University Bangladesh, BGC Biddyanagar, Chandanaish, Chittagong, Bangladesh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Assistant Professor, Department of Pharmacy, BGC Trust University Bangladesh, BGC Biddyanagar, Chandanaish, Chittagong, Bangladesh","institution_ids":["https://openalex.org/I3132920206"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053820283","display_name":"Sumaya Sultana","orcid":"https://orcid.org/0009-0000-4004-6503","observed_orcids":["https://orcid.org/0009-0000-4004-6503","https://orcid.org/0009-0004-1706-8535"]},"institutions":[{"id":"https://openalex.org/I3132920206","display_name":"BGC Trust University Bangladesh","ror":"https://ror.org/05s2ecw65","country_code":"BD","type":"education","lineage":["https://openalex.org/I3132920206"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Sumaya Sultana","raw_affiliation_strings":["Research Fellow, Department of Pharmacy, BGC Trust University Bangladesh, BGC Biddyanagar, Chandanaish, Chittagong, Bangladesh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Fellow, Department of Pharmacy, BGC Trust University Bangladesh, BGC Biddyanagar, Chandanaish, Chittagong, Bangladesh","institution_ids":["https://openalex.org/I3132920206"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5154869615","display_name":"Nabila Tazneen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3132920206","display_name":"BGC Trust University Bangladesh","ror":"https://ror.org/05s2ecw65","country_code":"BD","type":"education","lineage":["https://openalex.org/I3132920206"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Nabila Tazneen","raw_affiliation_strings":["Research Fellow, Department of Pharmacy, BGC Trust University Bangladesh, BGC Biddyanagar, Chandanaish, Chittagong, Bangladesh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Fellow, Department of Pharmacy, BGC Trust University Bangladesh, BGC Biddyanagar, Chandanaish, Chittagong, Bangladesh","institution_ids":["https://openalex.org/I3132920206"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5154056101","display_name":"Sushmoy Barua","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3132920206","display_name":"BGC Trust University Bangladesh","ror":"https://ror.org/05s2ecw65","country_code":"BD","type":"education","lineage":["https://openalex.org/I3132920206"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Sushmoy Barua","raw_affiliation_strings":["Research Fellow, Department of Pharmacy, BGC Trust University Bangladesh, BGC Biddyanagar, Chandanaish, Chittagong, Bangladesh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Fellow, Department of Pharmacy, BGC Trust University Bangladesh, BGC Biddyanagar, Chandanaish, Chittagong, Bangladesh","institution_ids":["https://openalex.org/I3132920206"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/leucas-zeylanica","display_name":"Leucas zeylanica","score":1.0},{"id":"https://openalex.org/keywords/antidiabetic-activity","display_name":"antidiabetic activity","score":0.9290000200271606},{"id":"https://openalex.org/keywords/aqueous-leaf-extract","display_name":"aqueous leaf extract","score":0.8960000276565552},{"id":"https://openalex.org/keywords/alloxan-induced-diabetes","display_name":"alloxan-induced diabetes","score":0.9980000257492065},{"id":"https://openalex.org/keywords/blood-glucose-reduction","display_name":"blood glucose reduction","score":0.8650000095367432},{"id":"https://openalex.org/keywords/glibenclamide","display_name":"glibenclamide","score":0.8500000238418579},{"id":"https://openalex.org/keywords/serum-insulin","display_name":"serum insulin","score":0.890999972820282},{"id":"https://openalex.org/keywords/liver-glycogen","display_name":"liver glycogen","score":0.9779999852180481},{"id":"https://openalex.org/keywords/body-weight","display_name":"body weight","score":0.765999972820282},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.703000009059906}],"concepts":[{"id":"https://openalex.org/C2779768347","wikidata":"https://www.wikidata.org/wiki/Q420626","display_name":"Glibenclamide","level":3,"score":0.8019999861717224},{"id":"https://openalex.org/C2993907526","wikidata":"https://www.wikidata.org/wiki/Q1259977","display_name":"Aqueous extract","level":2,"score":0.6559000015258789},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6380000114440918},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6080999970436096},{"id":"https://openalex.org/C2780545260","wikidata":"https://www.wikidata.org/wiki/Q5643307","display_name":"Leucas","level":2,"score":0.5947999954223633},{"id":"https://openalex.org/C2781005915","wikidata":"https://www.wikidata.org/wiki/Q417701","display_name":"Alloxan","level":3,"score":0.559499979019165},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.49459999799728394},{"id":"https://openalex.org/C147583825","wikidata":"https://www.wikidata.org/wiki/Q620876","display_name":"Body weight","level":2,"score":0.46480000019073486},{"id":"https://openalex.org/C2780485761","wikidata":"https://www.wikidata.org/wiki/Q275157","display_name":"Blood sugar","level":3,"score":0.4242999851703644},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.3846000134944916},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34769999980926514},{"id":"https://openalex.org/C2777499176","wikidata":"https://www.wikidata.org/wiki/Q174936","display_name":"Glycogen","level":2,"score":0.34360000491142273},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.33469998836517334},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.31310001015663147},{"id":"https://openalex.org/C160492267","wikidata":"https://www.wikidata.org/wiki/Q319616","display_name":"Pharmacognosy","level":4,"score":0.26100000739097595},{"id":"https://openalex.org/C2779158651","wikidata":"https://www.wikidata.org/wiki/Q188840","display_name":"Medicinal plants","level":2,"score":0.25279998779296875}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:ojs2.jipbs.com:article/198","doi":null,"is_oa":true,"landing_page_url":"https://jipbs.com/index.php/journal/article/view/198","pdf_url":"https://jipbs.com/index.php/journal/article/download/198/173","source":{"id":"https://openalex.org/S4387283359","display_name":"Journal of Innovations in Pharmaceutical and Biological Sciences","issn_l":"2349-2759","issn":["2349-2759","2395-1095"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2395-1095","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:ojs2.jipbs.com:article/198","doi":null,"is_oa":true,"landing_page_url":"https://jipbs.com/index.php/journal/article/view/198","pdf_url":"https://jipbs.com/index.php/journal/article/download/198/173","source":{"id":"https://openalex.org/S4387283359","display_name":"Journal of Innovations in Pharmaceutical and Biological Sciences","issn_l":"2349-2759","issn":["2349-2759","2395-1095"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2395-1095","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320316426","display_name":"University of Chittagong","ror":"https://ror.org/01173vs27"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7216625994.pdf","grobid_xml":"https://content.openalex.org/works/W7216625994.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2945719743","https://openalex.org/W105448296","https://openalex.org/W1540913338","https://openalex.org/W2803254788","https://openalex.org/W3216235730","https://openalex.org/W2809714814","https://openalex.org/W7164842761","https://openalex.org/W2094633324","https://openalex.org/W2548519934","https://openalex.org/W4401333929"],"abstract_inverted_index":{"The":[0],"study":[1],"was":[2,133],"designed":[3],"to":[4,46,107],"evaluate":[5],"the":[6,12,20,26,53,59,74,86,90,104,108,127],"blood":[7,76],"glucose":[8,77],"lowering":[9],"effect":[10],"of":[11,15,39,55],"aqueous":[13],"extract":[14,36,66,105],"Leucas":[16,40,64,140],"zeylanica":[17,41,65,141],"leaf":[18],"using":[19],"alloxan-induced":[21,60],"diabetic":[22,29,50,61,109,114,143],"rats":[23,51,110],"and":[24,31,42,48,98,116],"compared":[25,112],"activity":[27],"with":[28,89,113],"control":[30,115],"antidiabetic":[32],"drug":[33],"(Glibenclamide).":[34],"Leaf":[35],"(50":[37,67],"mg/kg)":[38,68],"Glibenclamide":[43],"were":[44,82,111,124],"administered":[45],"normal":[47,117],"experimental":[49],"for":[52],"duration":[54],"10":[56],"days.":[57],"In":[58,92],"rat":[62],"model,":[63],"significantly":[69,135],"(P":[70,121,136],"<":[71,122,137],"0.05)":[72,123,138],"lowered":[73],"fasting":[75],"level.":[78],"Serum":[79],"insulin":[80],"levels":[81,101],"not":[83],"stimulated":[84],"in":[85,95,103,126,139],"animals":[87],"treated":[88,106,142],"extract.":[91],"addition,":[93],"changes":[94],"body":[96,131],"weight":[97,132],"liver":[99],"glycogen":[100],"assessed":[102],"rats.":[118],"Significant":[119],"results":[120],"observed":[125],"estimated":[128],"parameters.":[129],"Surprisingly,":[130],"increased":[134],"group.":[144]},"counts_by_year":[],"updated_date":"2026-10-05T09:50:58.205359","created_date":"2026-10-03T00:00:00"}