{"id":"https://openalex.org/W7216550265","doi":"https://doi.org/10.3390/jcm15197649","title":"Prospective Comparison of Cognitive MRI-Targeted Biopsy Under Micro-Ultrasound Guidance Versus MRI/Ultrasound Fusion-Guided Transperineal Biopsy for Clinically Significant Prostate Cancer Detection","display_name":"Prospective Comparison of Cognitive MRI-Targeted Biopsy Under Micro-Ultrasound Guidance Versus MRI/Ultrasound Fusion-Guided Transperineal Biopsy for Clinically Significant Prostate Cancer Detection","publication_year":2026,"publication_date":"2026-10-02","ids":{"openalex":"https://openalex.org/W7216550265","doi":"https://doi.org/10.3390/jcm15197649","pmid":"https://pubmed.ncbi.nlm.nih.gov/42882109","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13666145"},"language":"en","primary_location":{"id":"doi:10.3390/jcm15197649","doi":"https://doi.org/10.3390/jcm15197649","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm15197649","pdf_url":null,"source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/jcm15197649","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064727378","display_name":"Agostino Fraia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210111929","display_name":"Azienda Ospedaliera S.Giuseppe Moscati","ror":"https://ror.org/021jxzw96","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210111929"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Agostino Fraia","raw_affiliation_strings":["Department of Urology, San Giuseppe Moscati Hospital, 81031 Aversa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, San Giuseppe Moscati Hospital, 81031 Aversa, Italy","institution_ids":["https://openalex.org/I4210111929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032912720","display_name":"Sara Riolo","orcid":"https://orcid.org/0009-0009-1139-6825","observed_orcids":["https://orcid.org/0009-0009-1139-6825"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Sara Riolo","raw_affiliation_strings":["Department of Urology, La Sapienza University, 00185 Rome, Italy"],"raw_orcid":"https://orcid.org/0009-0009-1139-6825","affiliations":[{"raw_affiliation_string":"Department of Urology, La Sapienza University, 00185 Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010733293","display_name":"Francesco Di Bello","orcid":"https://orcid.org/0000-0002-8585-3701","observed_orcids":["https://orcid.org/0000-0002-8585-3701"]},"institutions":[{"id":"https://openalex.org/I4210143013","display_name":"Puigvert Foundation","ror":"https://ror.org/03qwx2883","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I4210143013"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Francesco Di Bello","raw_affiliation_strings":["Department of Urology, Fundaci\u00f3 Puigvert, 08025 Barcelona, Spain"],"raw_orcid":"https://orcid.org/0000-0002-8585-3701","affiliations":[{"raw_affiliation_string":"Department of Urology, Fundaci\u00f3 Puigvert, 08025 Barcelona, Spain","institution_ids":["https://openalex.org/I4210143013"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5095042570","display_name":"Salvatore Papi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210111929","display_name":"Azienda Ospedaliera S.Giuseppe Moscati","ror":"https://ror.org/021jxzw96","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210111929"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Salvatore Papi","raw_affiliation_strings":["Department of Urology, San Giuseppe Moscati Hospital, 81031 Aversa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, San Giuseppe Moscati Hospital, 81031 Aversa, Italy","institution_ids":["https://openalex.org/I4210111929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5118594567","display_name":"Dario Brunello","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I119439378","display_name":"University of Verona","ror":"https://ror.org/039bp8j42","country_code":"IT","type":"education","lineage":["https://openalex.org/I119439378"]},{"id":"https://openalex.org/I4210094363","display_name":"Azienda Ospedaliera Universitaria Integrata Verona","ror":"https://ror.org/00sm8k518","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094363"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Dario Brunello","raw_affiliation_strings":["Urology Unit, Department of Surgery, Dentistry, Pediatrics and Gynecology, Azienda Ospedaliera Universitaria Integrata, University of Verona, 37126 Verona, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Urology Unit, Department of Surgery, Dentistry, Pediatrics and Gynecology, Azienda Ospedaliera Universitaria Integrata, University of Verona, 37126 Verona, Italy","institution_ids":["https://openalex.org/I119439378","https://openalex.org/I4210094363"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066834792","display_name":"Gianluca Nesi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gianluca Nesi","raw_affiliation_strings":["Department of Urology, La Sapienza University, 00185 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, La Sapienza University, 00185 Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076098733","display_name":"Ivan Di Giulio","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125680","display_name":"Ospedale San Bassiano","ror":"https://ror.org/02xqze381","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210125680"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Ivan Di Giulio","raw_affiliation_strings":["Department of Urology, San Bassiano Hospital, 36061 Bassano del Grappa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, San Bassiano Hospital, 36061 Bassano del Grappa, Italy","institution_ids":["https://openalex.org/I4210125680"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5154987963","display_name":"Giovanni Costa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125680","display_name":"Ospedale San Bassiano","ror":"https://ror.org/02xqze381","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210125680"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giovanni Costa","raw_affiliation_strings":["Department of Urology, San Bassiano Hospital, 36061 Bassano del Grappa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, San Bassiano Hospital, 36061 Bassano del Grappa, Italy","institution_ids":["https://openalex.org/I4210125680"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038622336","display_name":"Roberto Knez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125680","display_name":"Ospedale San Bassiano","ror":"https://ror.org/02xqze381","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210125680"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Roberto Knez","raw_affiliation_strings":["Department of Urology, San Bassiano Hospital, 36061 Bassano del Grappa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, San Bassiano Hospital, 36061 Bassano del Grappa, Italy","institution_ids":["https://openalex.org/I4210125680"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082126873","display_name":"Tommaso Silvestri","orcid":"https://orcid.org/0000-0001-8195-7784","observed_orcids":["https://orcid.org/0000-0001-8195-7784"]},"institutions":[{"id":"https://openalex.org/I4210125680","display_name":"Ospedale San Bassiano","ror":"https://ror.org/02xqze381","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210125680"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Tommaso Silvestri","raw_affiliation_strings":["Department of Urology, San Bassiano Hospital, 36061 Bassano del Grappa, Italy"],"raw_orcid":"https://orcid.org/0000-0001-8195-7784","affiliations":[{"raw_affiliation_string":"Department of Urology, San Bassiano Hospital, 36061 Bassano del Grappa, Italy","institution_ids":["https://openalex.org/I4210125680"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081944305","display_name":"Bernardino DE CONCILIO","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125680","display_name":"Ospedale San Bassiano","ror":"https://ror.org/02xqze381","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210125680"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Bernardino de Concilio","raw_affiliation_strings":["Department of Urology, San Bassiano Hospital, 36061 Bassano del Grappa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, San Bassiano Hospital, 36061 Bassano del Grappa, Italy","institution_ids":["https://openalex.org/I4210125680"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024289541","display_name":"Massimiliano Creta","orcid":"https://orcid.org/0000-0003-2082-3330","observed_orcids":["https://orcid.org/0000-0003-2082-3330"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Massimiliano Creta","raw_affiliation_strings":["Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples \u201cFederico II\u201d, 80131 Naples, Italy"],"raw_orcid":"https://orcid.org/0000-0003-2082-3330","affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples \u201cFederico II\u201d, 80131 Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001056677","display_name":"Raffaele Ranavolo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210111929","display_name":"Azienda Ospedaliera S.Giuseppe Moscati","ror":"https://ror.org/021jxzw96","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210111929"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Raffaele Ranavolo","raw_affiliation_strings":["Department of Urology, San Giuseppe Moscati Hospital, 81031 Aversa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, San Giuseppe Moscati Hospital, 81031 Aversa, Italy","institution_ids":["https://openalex.org/I4210111929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032217427","display_name":"Nicola Longo","orcid":"https://orcid.org/0009-0009-3394-0596","observed_orcids":["https://orcid.org/0009-0009-3394-0596","https://orcid.org/0000-0002-9509-8906"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Nicola Longo","raw_affiliation_strings":["Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples \u201cFederico II\u201d, 80131 Naples, Italy"],"raw_orcid":"https://orcid.org/0009-0009-3394-0596","affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples \u201cFederico II\u201d, 80131 Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090622338","display_name":"Guglielmo Zeccolini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125680","display_name":"Ospedale San Bassiano","ror":"https://ror.org/02xqze381","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210125680"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Guglielmo Zeccolini","raw_affiliation_strings":["Department of Urology, San Bassiano Hospital, 36061 Bassano del Grappa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, San Bassiano Hospital, 36061 Bassano del Grappa, Italy","institution_ids":["https://openalex.org/I4210125680"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103923823","display_name":"Antonio Celia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125680","display_name":"Ospedale San Bassiano","ror":"https://ror.org/02xqze381","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210125680"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonio Celia","raw_affiliation_strings":["Department of Urology, San Bassiano Hospital, 36061 Bassano del Grappa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, San Bassiano Hospital, 36061 Bassano del Grappa, Italy","institution_ids":["https://openalex.org/I4210125680"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5064727378"],"corresponding_institution_ids":["https://openalex.org/I4210111929"],"apc_list":{"value":2600,"currency":"CHF","value_usd":3137},"apc_paid":{"value":2600,"currency":"CHF","value_usd":3137},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.75751342,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"15","issue":"19","first_page":"7649","last_page":"7649"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.8740000128746033},{"id":"https://openalex.org/keywords/mri-ultrasound-fusion-biopsy","display_name":"MRI-ultrasound fusion biopsy","score":0.5860000252723694},{"id":"https://openalex.org/keywords/transperineal-prostate-biopsy","display_name":"transperineal prostate biopsy","score":0.9860000014305115},{"id":"https://openalex.org/keywords/transrectal-ultrasound","display_name":"transrectal ultrasound","score":0.699999988079071},{"id":"https://openalex.org/keywords/multiparametric-mri","display_name":"multiparametric MRI","score":0.824999988079071},{"id":"https://openalex.org/keywords/clinically-significant-prostate-cancer-detection","display_name":"clinically significant prostate cancer detection","score":0.9169999957084656},{"id":"https://openalex.org/keywords/psa-density","display_name":"PSA density","score":0.7799999713897705},{"id":"https://openalex.org/keywords/pi-rads","display_name":"PI-RADS","score":0.4880000054836273},{"id":"https://openalex.org/keywords/biopsy-technique-comparison","display_name":"biopsy technique comparison","score":0.5529999732971191},{"id":"https://openalex.org/keywords/isup-grade-group","display_name":"ISUP grade group","score":0.6169999837875366},{"id":"https://openalex.org/keywords/prostate-cancer-diagnosis","display_name":"prostate cancer diagnosis","score":0.37599998712539673}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9485999941825867},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.7709000110626221},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.7505000233650208},{"id":"https://openalex.org/C2781217009","wikidata":"https://www.wikidata.org/wiki/Q4086927","display_name":"Prostate biopsy","level":4,"score":0.5134000182151794},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.5095999836921692},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.45210000872612},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.4187999963760376},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.38940000534057617},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.37790000438690186},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.3637000024318695},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.34060001373291016},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.3325999975204468},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.33059999346733093},{"id":"https://openalex.org/C2985322473","wikidata":"https://www.wikidata.org/wiki/Q3044843","display_name":"Cancer detection","level":3,"score":0.3255000114440918},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.30390000343322754},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.2946999967098236},{"id":"https://openalex.org/C203092338","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Clinical endpoint","level":3,"score":0.29409998655319214},{"id":"https://openalex.org/C2781406297","wikidata":"https://www.wikidata.org/wiki/Q409450","display_name":"Prostate-specific antigen","level":4,"score":0.2833999991416931},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.2775999903678894},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.2572000026702881},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.25189998745918274}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.3390/jcm15197649","doi":"https://doi.org/10.3390/jcm15197649","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm15197649","pdf_url":null,"source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13666145","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13666145/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13666145/pdf/jcm-15-07649.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Med","raw_type":"Text"},{"id":"pmid:42882109","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42882109","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical medicine","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3390/jcm15197649","doi":"https://doi.org/10.3390/jcm15197649","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm15197649","pdf_url":null,"source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7216550265.pdf","grobid_xml":"https://content.openalex.org/works/W7216550265.grobid-xml"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W2154692607","https://openalex.org/W2340422569","https://openalex.org/W2793905111","https://openalex.org/W2898522880","https://openalex.org/W2901859788","https://openalex.org/W2922071185","https://openalex.org/W3010331388","https://openalex.org/W3016919090","https://openalex.org/W3017257963","https://openalex.org/W3041789325","https://openalex.org/W3183065453","https://openalex.org/W4321253077","https://openalex.org/W4393988897","https://openalex.org/W4394787252","https://openalex.org/W4401476333","https://openalex.org/W4402366211","https://openalex.org/W4402467297","https://openalex.org/W4408763728","https://openalex.org/W4414562768","https://openalex.org/W7172525614"],"related_works":["https://openalex.org/W4280528772","https://openalex.org/W7017783340","https://openalex.org/W4405542118","https://openalex.org/W3182797934","https://openalex.org/W2301519626","https://openalex.org/W4363677723","https://openalex.org/W2929119161","https://openalex.org/W2995898362","https://openalex.org/W4313784211","https://openalex.org/W4200345050"],"abstract_inverted_index":{"Background/Objectives:":[0],"Multiparametric":[1],"magnetic":[2],"resonance":[3],"imaging":[4],"(mpMRI)-targeted":[5],"biopsy":[6,54,59,114,160,168,213,282],"has":[7],"become":[8],"central":[9],"to":[10,179,203],"prostate":[11],"cancer":[12],"(PCa)":[13],"diagnosis.":[14],"While":[15],"cognitive":[16,36,56,166],"and":[17,80,93,125,162],"software-based":[18],"fusion":[19,277],"targeting":[20,263],"have":[21],"already":[22],"been":[23],"compared,":[24],"the":[25,121,158,165,189,244,269],"use":[26],"of":[27,38,142],"high-resolution":[28],"micro-ultrasound":[29,63,266],"as":[30,139,275],"a":[31,68,89,110,279],"real-time":[32,61,265],"guidance":[33,267],"platform":[34],"for":[35],"translation":[37],"MRI-defined":[39,122],"lesions":[40],"remains":[41],"incompletely":[42],"characterized.":[43],"This":[44],"study":[45,72],"prospectively":[46],"compared":[47],"mpMRI-transrectal":[48],"ultrasound":[49],"(TRUS)":[50],"fusion-guided":[51,159],"transperineal":[52],"(TP)":[53],"with":[55,77,88,218,240],"MRI-targeted":[57,167],"TP":[58,113],"under":[60,264],"ExactVu\u00ae":[62],"guidance.":[64],"Methods:":[65],"We":[66],"conducted":[67],"prospective,":[69],"observational,":[70],"comparative":[71],"including":[73],"58":[74],"consecutive":[75],"patients":[76,101],"suspected":[78],"PCa":[79,135,153],"at":[81],"least":[82],"one":[83],"lesion":[84,124],"on":[85],"pre-biopsy":[86],"mpMRI":[87],"Prostate":[90],"Imaging":[91],"Reporting":[92],"Data":[94],"System":[95],"(PI-RADS)":[96],"score":[97],"\u2265":[98,149],"3.":[99],"Twenty-nine":[100],"were":[102],"included":[103],"in":[104,157,164,188,243],"each":[105],"group.":[106],"The":[107,129],"analysis":[108],"used":[109],"standardized":[111,280],"16-core":[112],"set":[115],"comprising":[116],"four":[117],"targeted":[118],"cores":[119],"from":[120],"index":[123],"12":[126],"systematic":[127],"cores.":[128],"primary":[130],"endpoint":[131],"was":[132,155,186,215],"clinically":[133],"significant":[134],"(csPCa)":[136],"detection,":[137],"defined":[138],"International":[140],"Society":[141],"Urological":[143],"Pathology":[144],"(ISUP)":[145],"Grade":[146],"Group":[147],"(GG)":[148],"2.":[150],"Results:":[151],"Overall,":[152],"detection":[154,185,220,242,273],"65.5%":[156],"group":[161,169],"55.2%":[163],"(absolute":[170],"risk":[171,195],"difference,":[172,196],"10.3":[173],"percentage":[174,198],"points;":[175,199],"95%":[176,200,226,254],"CI,":[177,201],"\u221214.1":[178],"33.2;":[180],"p":[181,205,229,257],"=":[182,206,230,258],"0.592).":[183],"csPCa":[184,219,241,272],"identical":[187],"two":[190],"groups":[191],"(37.9%":[192],"each;":[193],"absolute":[194],"0.0":[197],"\u221223.6":[202],"23.6;":[204],"1.000).":[207],"In":[208],"exploratory":[209,245],"multivariable":[210,246],"logistic":[211],"regression,":[212],"technique":[214],"not":[216],"associated":[217],"after":[221],"adjustment":[222],"(adjusted":[223,248],"OR":[224,249],"0.73,":[225],"CI":[227,255],"0.22\u20132.40;":[228],"0.605),":[231],"whereas":[232],"prostate-specific":[233],"antigen":[234],"density":[235],"(PSAD)":[236],"showed":[237,268],"an":[238],"association":[239],"model":[247],"1.96":[250],"per":[251],"0.1-unit":[252],"increase,":[253],"1.04\u20133.71;":[256],"0.039).":[259],"Conclusions:":[260],"Cognitive":[261],"MRI":[262],"same":[270],"observed":[271],"rate":[274],"software":[276],"within":[278],"targeted-plus-systematic":[281],"pathway.":[283],"Wide":[284],"confidence":[285],"intervals":[286],"preclude":[287],"conclusions":[288],"regarding":[289],"equivalence":[290],"or":[291],"non-inferiority.":[292]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-10-03T00:00:00"}