{"id":"https://openalex.org/W7216427728","doi":"https://doi.org/10.3389/fcvm.2026.1919383","title":"Thrombus burden-stratified catheter-directed thrombolysis combined with percutaneous transluminal angioplasty for acute arteriovenous graft thrombosis in hemodialysis patients: a comparison of single-session versus extended infusion protocols","display_name":"Thrombus burden-stratified catheter-directed thrombolysis combined with percutaneous transluminal angioplasty for acute arteriovenous graft thrombosis in hemodialysis patients: a comparison of single-session versus extended infusion protocols","publication_year":2026,"publication_date":"2026-10-02","ids":{"openalex":"https://openalex.org/W7216427728","doi":"https://doi.org/10.3389/fcvm.2026.1919383","pmid":"https://pubmed.ncbi.nlm.nih.gov/42890168","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13672488"},"language":"en","primary_location":{"id":"doi:10.3389/fcvm.2026.1919383","doi":"https://doi.org/10.3389/fcvm.2026.1919383","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fcvm.2026.1919383","pdf_url":"https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2026.1919383/pdf","source":{"id":"https://openalex.org/S2595413687","display_name":"Frontiers in Cardiovascular Medicine","issn_l":"2297-055X","issn":["2297-055X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cardiovascular Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2026.1919383/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100427368","display_name":"Bin Chen","orcid":"https://orcid.org/0000-0002-6869-1843","observed_orcids":["https://orcid.org/0000-0002-6869-1843","https://orcid.org/0009-0003-8133-7747"]},"institutions":[{"id":"https://openalex.org/I4210128921","display_name":"The First Affiliated Hospital, Sun Yat-sen University","ror":"https://ror.org/037p24858","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128921"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bin Chen","raw_affiliation_strings":["Department of Interventional Radiology, Hui Ya Hospital of The First Affiliated Hospital of Sun Yat-Sen University","Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-Sen University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Interventional Radiology, Hui Ya Hospital of The First Affiliated Hospital of Sun Yat-Sen University","institution_ids":["https://openalex.org/I4210128921"]},{"raw_affiliation_string":"Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-Sen University","institution_ids":["https://openalex.org/I4210128921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5144329960","display_name":"Keyu Tang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210128921","display_name":"The First Affiliated Hospital, Sun Yat-sen University","ror":"https://ror.org/037p24858","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128921"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Keyu Tang","raw_affiliation_strings":["Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-Sen University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-Sen University","institution_ids":["https://openalex.org/I4210128921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5155279274","display_name":"Xiaoyuan Lin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210128921","display_name":"The First Affiliated Hospital, Sun Yat-sen University","ror":"https://ror.org/037p24858","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128921"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoyuan Lin","raw_affiliation_strings":["Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-Sen University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-Sen University","institution_ids":["https://openalex.org/I4210128921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5144314818","display_name":"Guiyuan Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210128921","display_name":"The First Affiliated Hospital, Sun Yat-sen University","ror":"https://ror.org/037p24858","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128921"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guiyuan Zhang","raw_affiliation_strings":["Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-Sen University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-Sen University","institution_ids":["https://openalex.org/I4210128921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068926815","display_name":"Run Lin","orcid":"https://orcid.org/0000-0003-3692-5753","observed_orcids":["https://orcid.org/0000-0003-3692-5753"]},"institutions":[{"id":"https://openalex.org/I4210128921","display_name":"The First Affiliated Hospital, Sun Yat-sen University","ror":"https://ror.org/037p24858","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128921"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Run Lin","raw_affiliation_strings":["Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-Sen University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-Sen University","institution_ids":["https://openalex.org/I4210128921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5154391860","display_name":"Haitao Dai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210128921","display_name":"The First Affiliated Hospital, Sun Yat-sen University","ror":"https://ror.org/037p24858","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128921"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haitao Dai","raw_affiliation_strings":["Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-Sen University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-Sen University","institution_ids":["https://openalex.org/I4210128921"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5155929257","display_name":"Yonghui Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210128921","display_name":"The First Affiliated Hospital, Sun Yat-sen University","ror":"https://ror.org/037p24858","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128921"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yonghui Huang","raw_affiliation_strings":["Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-Sen University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-Sen University","institution_ids":["https://openalex.org/I4210128921"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5155929257"],"corresponding_institution_ids":["https://openalex.org/I4210128921"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.73230604,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"13","issue":null,"first_page":"1919383","last_page":"1919383"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10641","display_name":"Central Venous Catheters and Hemodialysis","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10641","display_name":"Central Venous Catheters and Hemodialysis","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12067","display_name":"Renal and Vascular Pathologies","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10926","display_name":"Peripheral Artery Disease Management","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/arteriovenous-graft-thrombosis","display_name":"arteriovenous graft thrombosis","score":0.9599999785423279},{"id":"https://openalex.org/keywords/catheter-directed-thrombolysis","display_name":"catheter-directed thrombolysis","score":0.9649999737739563},{"id":"https://openalex.org/keywords/percutaneous-transluminal-angioplasty","display_name":"percutaneous transluminal angioplasty","score":0.9700000286102295},{"id":"https://openalex.org/keywords/thrombus-burden","display_name":"thrombus burden","score":0.8600000143051147},{"id":"https://openalex.org/keywords/hemodialysis-vascular-access","display_name":"hemodialysis vascular access","score":0.8659999966621399},{"id":"https://openalex.org/keywords/graft-patency","display_name":"graft patency","score":0.8109999895095825},{"id":"https://openalex.org/keywords/septic-shock","display_name":"septic shock","score":0.5299999713897705},{"id":"https://openalex.org/keywords/shared-frailty-model","display_name":"shared frailty model","score":0.6259999871253967}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9532999992370605},{"id":"https://openalex.org/C2781362458","wikidata":"https://www.wikidata.org/wiki/Q1588755","display_name":"Thrombus","level":2,"score":0.7577999830245972},{"id":"https://openalex.org/C2778063415","wikidata":"https://www.wikidata.org/wiki/Q391744","display_name":"Hemodialysis","level":2,"score":0.7077999711036682},{"id":"https://openalex.org/C2779581417","wikidata":"https://www.wikidata.org/wiki/Q1931577","display_name":"Thrombolysis","level":3,"score":0.6615999937057495},{"id":"https://openalex.org/C2780868729","wikidata":"https://www.wikidata.org/wiki/Q261327","display_name":"Thrombosis","level":2,"score":0.5388000011444092},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5314000248908997},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.5307999849319458},{"id":"https://openalex.org/C203092338","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Clinical endpoint","level":3,"score":0.49390000104904175},{"id":"https://openalex.org/C2780813298","wikidata":"https://www.wikidata.org/wiki/Q2071287","display_name":"Percutaneous","level":2,"score":0.45500001311302185},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3937999904155731},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.38960000872612},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.387800008058548},{"id":"https://openalex.org/C2776268601","wikidata":"https://www.wikidata.org/wiki/Q968808","display_name":"Occlusion","level":2,"score":0.3772999942302704},{"id":"https://openalex.org/C38180746","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate analysis","level":2,"score":0.35510000586509705},{"id":"https://openalex.org/C2780011451","wikidata":"https://www.wikidata.org/wiki/Q2751330","display_name":"Venous thrombosis","level":3,"score":0.35120001435279846},{"id":"https://openalex.org/C2780326628","wikidata":"https://www.wikidata.org/wiki/Q539795","display_name":"Angioplasty","level":2,"score":0.33739998936653137},{"id":"https://openalex.org/C3019775111","wikidata":"https://www.wikidata.org/wiki/Q391744","display_name":"Hemodialysis access","level":4,"score":0.3287999927997589},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.31200000643730164},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.3100000023841858},{"id":"https://openalex.org/C2777202286","wikidata":"https://www.wikidata.org/wiki/Q9609","display_name":"Vein","level":2,"score":0.2946999967098236},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.2906999886035919},{"id":"https://openalex.org/C8443397","wikidata":"https://www.wikidata.org/wiki/Q15177","display_name":"Anastomosis","level":2,"score":0.28760001063346863},{"id":"https://openalex.org/C2780643987","wikidata":"https://www.wikidata.org/wiki/Q468414","display_name":"Angiography","level":2,"score":0.2720000147819519},{"id":"https://openalex.org/C141341695","wikidata":"https://www.wikidata.org/wiki/Q2368661","display_name":"Surrogate endpoint","level":2,"score":0.26660001277923584},{"id":"https://openalex.org/C2777339539","wikidata":"https://www.wikidata.org/wiki/Q6993039","display_name":"Neointima","level":4,"score":0.258899986743927},{"id":"https://openalex.org/C2909817843","wikidata":"https://www.wikidata.org/wiki/Q575222","display_name":"Fibrinolytic agent","level":3,"score":0.2551000118255615}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fcvm.2026.1919383","doi":"https://doi.org/10.3389/fcvm.2026.1919383","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fcvm.2026.1919383","pdf_url":"https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2026.1919383/pdf","source":{"id":"https://openalex.org/S2595413687","display_name":"Frontiers in Cardiovascular Medicine","issn_l":"2297-055X","issn":["2297-055X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cardiovascular Medicine","raw_type":"journal-article"},{"id":"pmid:42890168","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42890168","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in cardiovascular medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13672488","doi":null,"is_oa":true,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42890168/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Cardiovasc Med","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:9d5fdb66293a4bcabc981fc1ba59e26c","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/9d5fdb66293a4bcabc981fc1ba59e26c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Cardiovascular Medicine, Vol 13 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fcvm.2026.1919383","doi":"https://doi.org/10.3389/fcvm.2026.1919383","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fcvm.2026.1919383","pdf_url":"https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2026.1919383/pdf","source":{"id":"https://openalex.org/S2595413687","display_name":"Frontiers in Cardiovascular Medicine","issn_l":"2297-055X","issn":["2297-055X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cardiovascular Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7216427728.pdf","grobid_xml":"https://content.openalex.org/works/W7216427728.grobid-xml"},"referenced_works_count":16,"referenced_works":["https://openalex.org/W1982735089","https://openalex.org/W2062304091","https://openalex.org/W2557814748","https://openalex.org/W2585979311","https://openalex.org/W2795534120","https://openalex.org/W2925236160","https://openalex.org/W3012497879","https://openalex.org/W3062066963","https://openalex.org/W4205233326","https://openalex.org/W4213079909","https://openalex.org/W4249574760","https://openalex.org/W4313626701","https://openalex.org/W4365457134","https://openalex.org/W4385898721","https://openalex.org/W4389036004","https://openalex.org/W4410232249"],"related_works":["https://openalex.org/W4403687233","https://openalex.org/W3005745059","https://openalex.org/W4408162087","https://openalex.org/W7149700504","https://openalex.org/W2947996558","https://openalex.org/W3042442063","https://openalex.org/W4407249858","https://openalex.org/W2014956686","https://openalex.org/W4413308811","https://openalex.org/W4225323902"],"abstract_inverted_index":{"Purpose":[0],"To":[1],"compare":[2],"single":[3],"session":[4],"(SS)":[5],"versus":[6],"extended":[7],"infusion":[8,287],"(EI)":[9],"catheter-directed":[10],"thrombolysis":[11],"(CDT)":[12],"combined":[13],"with":[14,20,35,88,102,225,331],"PTA":[15],"for":[16,153],"acute":[17,36],"AVG":[18,37,52],"thrombosis,":[19],"allocation":[21],"based":[22],"on":[23,80],"thrombus":[24,84,94,108],"burden":[25,85,95,109],"and":[26,43,64,83,128,134,145,204,242],"lesion":[27,309],"morphology.":[28],"Methods":[29],"This":[30],"study":[31],"included":[32,122],"hemodialysis":[33],"patients":[34,47,87,164],"thrombosis":[38],"treated":[39],"between":[40],"April":[41],"2020":[42],"September":[44],"2023.":[45],"All":[46],"underwent":[48],"angiographic":[49],"classification":[50,82],"of":[51,159,193],"stenosis/occlusion":[53],"into":[54],"two":[55],"morphological":[56],"types:":[57],"Type":[58,65,89,103,194,234],"I":[59,90],"(isolated":[60],"venous":[61,77],"anastomotic":[62],"stenosis/occlusion)":[63],"II":[66,104,195,235],"(complex,":[67],"multi-segment":[68],"occlusion":[69],"involving":[70],"the":[71,201,208,268,313],"arterial":[72],"anastomosis,":[73],"graft":[74,219,324],"lumen,":[75],"and/or":[76],"anastomosis).":[78],"Based":[79],"this":[81],"assessment,":[86],"lesions":[91,105,196],"or":[92,106,308],"low":[93],"received":[96,110],"SS-CDT":[97,180,202],"+":[98,112],"PTA,":[99],"while":[100,233],"those":[101],"high":[107],"EI-CDT":[111,184,209,269,292],"PTA.":[113],"The":[114,191],"primary":[115,118,176,333],"endpoint":[116],"was":[117,178,197,223,252,288,328],"patency.":[119,130],"Secondary":[120],"endpoints":[121],"technical":[123],"success":[124,251],"rate,":[125],"procedure-related":[126],"complications,":[127],"secondary":[129],"Kaplan\u2013Meier":[131],"survival":[132],"analysis":[133,148],"multivariate":[135,216],"Cox":[136,217],"proportional":[137],"hazards":[138],"regression":[139],"were":[140,149,165,273,300],"performed.":[141],"A":[142,157],"shared-frailty":[143],"model":[144],"patient-level":[146],"sensitivity":[147],"used":[150],"to":[151,295],"account":[152],"within-patient":[154],"clustering.":[155],"Results":[156],"total":[158],"105":[160],"procedures":[161,293],"in":[162,200,207,254,267,290],"89":[163],"analyzed":[166],"(SS-CDT,":[167],"n":[168,172],"=":[169,173,189,213,231,240,248,338],"73;":[170],"EI-CDT,":[171],"32).":[174],"Median":[175],"patency":[177,227,334],"comparable:":[179],"183":[181,185],"days":[182,186],"vs.":[183,280],"(log-rank":[187],"p":[188,212,230,239,247,283,337],"0.867).":[190],"proportion":[192],"80.8%":[198],"(59/73)":[199],"group":[203,210],"90.6%":[205],"(29/32)":[206],"(":[211],"0.261).":[214],"On":[215],"regression,":[218],"age":[220,325],">24":[221,326],"months":[222,327],"associated":[224,330],"improved":[226,332],"(HR":[228,237,245,335],"0.59,":[229,336],"0.023),":[232,339],"morphology":[236],"0.80,":[238],"0.428)":[241],"CDT":[243,305],"protocol":[244,306],"0.91,":[246],"0.79).":[249],"Technical":[250],"100%":[253],"both":[255],"groups":[256],"(excluding":[257],"7":[258],"crossover":[259],"procedures).":[260],"One":[261],"major":[262],"complication":[263],"(septic":[264],"shock)":[265],"occurred":[266],"group.":[270],"Minor":[271],"complications":[272],"comparable,":[274],"except":[275],"puncture-site":[276],"bleeding":[277],"(EI-CDT:":[278],"18.8%":[279],"SS-CDT:":[281],"0%,":[282],"<":[284],"0.001).":[285],"Urokinase":[286],"interrupted":[289],"2":[291],"due":[294],"bleeding.":[296],"Conclusions":[297],"Patency":[298],"outcomes":[299,319],"not":[301],"significantly":[302],"influenced":[303],"by":[304],"duration":[307],"morphology,":[310],"suggesting":[311],"that":[312],"stratified":[314],"treatment":[315,351],"approach":[316],"effectively":[317],"equalized":[318],"across":[320],"clinical":[321],"contexts;":[322],"notably,":[323],"independently":[329],"a":[340,349],"finding":[341],"most":[342],"plausibly":[343],"reflecting":[344],"survivor-graft":[345],"bias":[346],"rather":[347],"than":[348],"true":[350],"effect.":[352]},"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2026-10-03T00:00:00"}