{"id":"https://openalex.org/W7215609232","doi":null,"title":"Cytotoxic correlation with BACCOR biopharmaceutical mass spectrometry in the biocorrosive process of endodontic files","display_name":"Cytotoxic correlation with BACCOR biopharmaceutical mass spectrometry in the biocorrosive process of endodontic files","publication_year":2022,"publication_date":"2022-10-10","ids":{"openalex":"https://openalex.org/W7215609232"},"language":"pt","primary_location":{"id":"pmh:oai:ojs.granrio.emnuvens.com.br:article/7325","doi":null,"is_oa":true,"landing_page_url":"https://publicacoes.unigranrio.edu.br/amp/article/view/7325","pdf_url":"https://publicacoes.unigranrio.edu.br/amp/article/download/7325/3688","source":{"id":"https://openalex.org/S4306501433","display_name":"Almanaque Multidisciplinar de Pesquisa","issn_l":"2359-6651","issn":["2359-6651"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2359-6651","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://publicacoes.unigranrio.edu.br/amp/article/download/7325/3688","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004138048","display_name":"Fabiano Luiz Heggendorn","orcid":"https://orcid.org/0000-0002-2687-0165","observed_orcids":["https://orcid.org/0000-0002-2687-0165"]},"institutions":[{"id":"https://openalex.org/I3019930557","display_name":"Universidade Unigranrio","ror":"https://ror.org/001fypf81","country_code":"BR","type":"education","lineage":["https://openalex.org/I3019930557"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Heggendorn, Fabiano Luiz","raw_affiliation_strings":["UNIGRANRIO\r\nPost Graduate Program in Dentistry (PPGO), Grande Rio University (UNIGRANRIO). Prof. Jos\u00e9 de Souza Herdy, 1.160 C- Duque de Caxias / Rio de Janeiro, Brazil - Zip Code: 25071-202"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UNIGRANRIO\r\nPost Graduate Program in Dentistry (PPGO), Grande Rio University (UNIGRANRIO). Prof. Jos\u00e9 de Souza Herdy, 1.160 C- Duque de Caxias / Rio de Janeiro, Brazil - Zip Code: 25071-202","institution_ids":["https://openalex.org/I3019930557"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047997739","display_name":"G. C. Silva","orcid":"https://orcid.org/0000-0002-9702-269X","observed_orcids":["https://orcid.org/0000-0002-9702-269X"]},"institutions":[{"id":"https://openalex.org/I122140584","display_name":"Universidade Federal do Rio de Janeiro","ror":"https://ror.org/03490as77","country_code":"BR","type":"education","lineage":["https://openalex.org/I122140584"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"da Silva, Gabriela Cristina Carvalho","raw_affiliation_strings":["Federal University of Rio de Janeiro School of Pharmacy, Pharmaceutical Bioassays Laboratory, Health Sciences Center, CCS, Bloco K, R050, University City, Zip Code: 21941-599, Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal University of Rio de Janeiro School of Pharmacy, Pharmaceutical Bioassays Laboratory, Health Sciences Center, CCS, Bloco K, R050, University City, Zip Code: 21941-599, Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I122140584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106657385","display_name":"Lucio Souza Gon\u00e7alves","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210131693","display_name":"Est\u00e1cio (Brazil)","ror":"https://ror.org/02vej5573","country_code":"BR","type":"company","lineage":["https://openalex.org/I4210131693"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Gon\u00e7alves, L\u00facio Souza","raw_affiliation_strings":["Faculty of Dentistry, Est\u00e1cio de S\u00e1 University - Rio de Janeiro, Av. Alfredo Baltazar da Silveira, 580, Zip Code: 22790-710, Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Dentistry, Est\u00e1cio de S\u00e1 University - Rio de Janeiro, Av. Alfredo Baltazar da Silveira, 580, Zip Code: 22790-710, Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I4210131693"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068261265","display_name":"Walter Barreiro Cravo","orcid":"https://orcid.org/0000-0001-6599-2563","observed_orcids":["https://orcid.org/0000-0001-6599-2563"]},"institutions":[{"id":"https://openalex.org/I4210107052","display_name":"Instituto Nacional de Tecnologia","ror":"https://ror.org/012ang229","country_code":"BR","type":"government","lineage":["https://openalex.org/I4210107052","https://openalex.org/I4210151455"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Cravo Junior, Walter Barreiro","raw_affiliation_strings":["Biocorrosion and Biodegradation Laboratory, National Institute of Technology, Av. Venezuela, 82, 6th floor, Pra\u00e7a Mau\u00e1, Zip Code: 200 81-312, Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biocorrosion and Biodegradation Laboratory, National Institute of Technology, Av. Venezuela, 82, 6th floor, Pra\u00e7a Mau\u00e1, Zip Code: 200 81-312, Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I4210107052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020104491","display_name":"M\u00e1rcia Teresa Soares Lutterbach","orcid":"https://orcid.org/0000-0002-4906-4975","observed_orcids":["https://orcid.org/0000-0002-4906-4975"]},"institutions":[{"id":"https://openalex.org/I4210107052","display_name":"Instituto Nacional de Tecnologia","ror":"https://ror.org/012ang229","country_code":"BR","type":"government","lineage":["https://openalex.org/I4210107052","https://openalex.org/I4210151455"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Lutterbach, Marcia Teresa Soares","raw_affiliation_strings":["Biocorrosion and Biodegradation Laboratory, National Institute of Technology, Av. Venezuela, 82, 6th floor, Pra\u00e7a Mau\u00e1, Zip Code: 200 81-312, Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biocorrosion and Biodegradation Laboratory, National Institute of Technology, Av. Venezuela, 82, 6th floor, Pra\u00e7a Mau\u00e1, Zip Code: 200 81-312, Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I4210107052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018439368","display_name":"Sabrina de Castro Brasil","orcid":"https://orcid.org/0000-0002-1412-7200","observed_orcids":["https://orcid.org/0000-0002-1412-7200"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brasil, Sabrina de Castro","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5069656714","display_name":"Viviane de Oliveira Freitas Lione","orcid":"https://orcid.org/0000-0003-4225-698X","observed_orcids":["https://orcid.org/0000-0003-4225-698X"]},"institutions":[{"id":"https://openalex.org/I122140584","display_name":"Universidade Federal do Rio de Janeiro","ror":"https://ror.org/03490as77","country_code":"BR","type":"education","lineage":["https://openalex.org/I122140584"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Lione, Viviane Oliveira Freitas","raw_affiliation_strings":["School of Pharmacy, Federal University of Rio de Janeiro, Laboratory of Pharmaceutical Bioassays, Health Sciences Center, CCS, Block K, Room 050 University City, Zip Code: 21941-599, Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, Federal University of Rio de Janeiro, Laboratory of Pharmaceutical Bioassays, Health Sciences Center, CCS, Block K, Room 050 University City, Zip Code: 21941-599, Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I122140584"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10536","display_name":"Endodontics and Root Canal Treatments","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10536","display_name":"Endodontics and Root Canal Treatments","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12744","display_name":"Medical Device Sterilization and Disinfection","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10310","display_name":"Corrosion Behavior and Inhibition","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/endodontic-files","display_name":"endodontic files","score":0.7879999876022339},{"id":"https://openalex.org/keywords/microbiologically-influenced-corrosion","display_name":"microbiologically influenced corrosion","score":0.9409999847412109},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.8289999961853027},{"id":"https://openalex.org/keywords/desulfovibrio-desulfuricans","display_name":"Desulfovibrio desulfuricans","score":0.972000002861023},{"id":"https://openalex.org/keywords/desulfovibrio-fairfieldensis","display_name":"Desulfovibrio fairfieldensis","score":0.996999979019165},{"id":"https://openalex.org/keywords/sulfate-reducing-bacteria","display_name":"sulfate-reducing bacteria","score":0.9959999918937683},{"id":"https://openalex.org/keywords/root-canal","display_name":"root canal","score":0.4449999928474426},{"id":"https://openalex.org/keywords/l929-fibroblasts","display_name":"L929 fibroblasts","score":0.7149999737739563},{"id":"https://openalex.org/keywords/vero-cells","display_name":"Vero cells","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cell-viability","display_name":"cell viability","score":0.5699999928474426},{"id":"https://openalex.org/keywords/culture-medium","display_name":"culture media","score":0.41999998688697815},{"id":"https://openalex.org/keywords/biomaterial-safety","display_name":"biomaterial safety","score":0.41200000047683716}],"concepts":[{"id":"https://openalex.org/C53227056","wikidata":"https://www.wikidata.org/wiki/Q189152","display_name":"Viability assay","level":3,"score":0.7738999724388123},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.7512999773025513},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5848000049591064},{"id":"https://openalex.org/C2778022156","wikidata":"https://www.wikidata.org/wiki/Q576145","display_name":"Strain (injury)","level":2,"score":0.5299999713897705},{"id":"https://openalex.org/C89138240","wikidata":"https://www.wikidata.org/wiki/Q3066564","display_name":"Vero cell","level":3,"score":0.5253999829292297},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.520799994468689},{"id":"https://openalex.org/C2780783641","wikidata":"https://www.wikidata.org/wiki/Q738686","display_name":"MTT assay","level":3,"score":0.504800021648407},{"id":"https://openalex.org/C57409179","wikidata":"https://www.wikidata.org/wiki/Q1218293","display_name":"Lysis","level":2,"score":0.49639999866485596},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4867999851703644},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.4812999963760376},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.46639999747276306},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.42289999127388},{"id":"https://openalex.org/C162356407","wikidata":"https://www.wikidata.org/wiki/Q180809","display_name":"Mass spectrometry","level":2,"score":0.392300009727478},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.37059998512268066},{"id":"https://openalex.org/C2781047461","wikidata":"https://www.wikidata.org/wiki/Q679692","display_name":"Biopharmaceutical","level":2,"score":0.35370001196861267},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.34380000829696655},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.3393999934196472},{"id":"https://openalex.org/C180032290","wikidata":"https://www.wikidata.org/wiki/Q1664296","display_name":"Inoculation","level":2,"score":0.33160001039505005},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.29109999537467957},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.2694999873638153},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.26080000400543213},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.25920000672340393}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:ojs.granrio.emnuvens.com.br:article/7325","doi":null,"is_oa":true,"landing_page_url":"https://publicacoes.unigranrio.edu.br/amp/article/view/7325","pdf_url":"https://publicacoes.unigranrio.edu.br/amp/article/download/7325/3688","source":{"id":"https://openalex.org/S4306501433","display_name":"Almanaque Multidisciplinar de Pesquisa","issn_l":"2359-6651","issn":["2359-6651"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2359-6651","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:ojs.granrio.emnuvens.com.br:article/7325","doi":null,"is_oa":true,"landing_page_url":"https://publicacoes.unigranrio.edu.br/amp/article/view/7325","pdf_url":"https://publicacoes.unigranrio.edu.br/amp/article/download/7325/3688","source":{"id":"https://openalex.org/S4306501433","display_name":"Almanaque Multidisciplinar de Pesquisa","issn_l":"2359-6651","issn":["2359-6651"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2359-6651","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7215609232.pdf","grobid_xml":"https://content.openalex.org/works/W7215609232.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4288034281","https://openalex.org/W2523812896","https://openalex.org/W2411818084","https://openalex.org/W3095834756","https://openalex.org/W2801069632","https://openalex.org/W4205889034","https://openalex.org/W4297347791","https://openalex.org/W4409503423","https://openalex.org/W4401595899","https://openalex.org/W4392809253"],"abstract_inverted_index":{"This":[0],"study":[1],"evaluated":[2],"the":[3,9,16,31,57,67,132,155,163,168,186,194],"biopharmaceutical":[4],"BACCOR,":[5],"developed":[6],"to":[7,154,210],"promote":[8],"biocorrosion":[10,34],"of":[11,21,33,35,61,69,118,162,171,185,222],"fractured":[12],"endodontic":[13],"files":[14],"inside":[15],"root":[17],"canal.":[18],"The":[19,52,159,175],"cytotoxicity":[20,93],"cell":[22,87,136,150,160,169,183,215],"extracts":[23,137],"was":[24,165],"evaluate":[25],"from":[26,138,179],"supernatants":[27,147,164],"and":[28,42,45,65,85,124,140,182,199,205],"pellets,":[29],"without":[30,109,127],"occurrence":[32],"two":[36],"species":[37,71],"Desulfovibrio":[38,46],"desulfuricans,":[39],"oral":[40],"strain":[41,64],"environmental":[43],"strain,":[44],"fairfieldensis":[47],"in":[48,73,77,193],"different":[49],"culture":[50,102],"media.":[51],"results":[53,192],"were":[54,89,96,143],"correlated":[55],"with":[56,66,196,206,213],"most":[58],"probable":[59],"number":[60],"each":[62],"bacterial":[63],"analysis":[68],"chemical":[70],"obtained":[72],"energy":[74],"dispersive":[75],"spectrometry":[76],"RX":[78],"under":[79],"a":[80,226],"scanning":[81],"electron":[82],"microscope.":[83],"L929":[84],"Vero":[86],"lines":[88],"used":[90],"for":[91],"MTT":[92],"tests.":[94],"Strains":[95],"inoculated":[97],"into":[98],"modified":[99],"Postgate":[100,107,113,125],"E":[101,108],"medium":[103],"(MCP-E":[104,111],"mod),":[105],"Modified":[106],"Agar-agar":[110,119,128],"s/Ag),":[112],"C":[114,126],"at":[115],"4":[116],"g./l.":[117],"(MCP-C":[120,129],"4.0":[121],"g/l":[122],"Ag)":[123],"s/Ag).":[130],"After":[131],"42-day":[133],"cultivation":[134],"periods":[135],"Supernatant":[139],"Cell":[141],"Pellet":[142],"prepared.":[144],"All":[145],"MCP-C":[146],"showed":[148,190],"lower":[149,166],"viability":[151,161,170,214],"when":[152],"compared":[153],"others":[156],"using":[157],"MCP-E.":[158],"than":[167],"their":[172],"respective":[173],"pellets.":[174],"test":[176],"compounds":[177],"originated":[178],"metabolic":[180],"products":[181],"lysates":[184],"Sulfate-reducing":[187],"Bacteria":[188],"strains":[189],"better":[191],"groups":[195],"MCP-E":[197],"s/Ag":[198],"MCPE-mod,":[200],"being":[201],"classified":[202],"as":[203,225],"non-cytotoxic":[204],"moderate":[207],"cytotoxicity,":[208],"according":[209],"ISO":[211],"categorization,":[212],"over":[216],"50%,":[217],"which":[218],"makes":[219],"this":[220],"type":[221],"inoculum":[223],"acceptable":[224],"biomaterial.":[227]},"counts_by_year":[],"updated_date":"2026-10-15T10:00:46.086208","created_date":"2026-10-02T00:00:00"}