{"id":"https://openalex.org/W7215486305","doi":null,"title":"Management of hypoxic-ischemic encephalopathy - current issues for the paediatrician","display_name":"Management of hypoxic-ischemic encephalopathy - current issues for the paediatrician","publication_year":2023,"publication_date":"2023-01-17","ids":{"openalex":"https://openalex.org/W7215486305"},"language":"en","primary_location":{"id":"pmh:oai:ojs2.belgjpaediatrics.com:article/17","doi":null,"is_oa":true,"landing_page_url":"https://www.belgjpaediatrics.com/index.php/bjp/article/view/17/201","pdf_url":"https://www.belgjpaediatrics.com/index.php/bjp/article/download/17/201/115","source":{"id":"https://openalex.org/S7407066516","display_name":"Belgian Journal of Paediatrics","issn_l":"2466-8907","issn":["2466-8907","2566-1558"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2466-8907","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.belgjpaediatrics.com/index.php/bjp/article/download/17/201/115","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014271690","display_name":"Barbara De Bisschop","orcid":"https://orcid.org/0000-0003-1672-5770","observed_orcids":["https://orcid.org/0000-0003-1672-5770"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"de Bisschop, Barbara","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5154267967","display_name":"Celine Perceval","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Perceval, Celine","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5151634885","display_name":"Marie-Julie Debuf","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Debuf, Marie-Julie","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5128754512","display_name":"Anne Smits","orcid":"https://orcid.org/0000-0002-0710-6698","observed_orcids":["https://orcid.org/0000-0002-0710-6698"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Smits, Anne","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022930226","display_name":"Liesbeth Thewissen","orcid":"https://orcid.org/0000-0002-0991-3776","observed_orcids":["https://orcid.org/0000-0002-0991-3776"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thewissen, Liesbeth","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5005743653","display_name":"Melanie Janssens","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Janssens, Melanie","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11861","display_name":"Thermal Regulation in Medicine","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11060","display_name":"Infant Development and Preterm Care","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypoxic-ischemic-encephalopathy","display_name":"hypoxic-ischemic encephalopathy","score":1.0},{"id":"https://openalex.org/keywords/perinatal-asphyxia","display_name":"perinatal asphyxia","score":1.0},{"id":"https://openalex.org/keywords/therapeutic-hypothermia","display_name":"therapeutic hypothermia","score":0.996999979019165},{"id":"https://openalex.org/keywords/neonatal-neuroprotection","display_name":"neonatal neuroprotection","score":0.7590000033378601},{"id":"https://openalex.org/keywords/neurodevelopmental-outcomes","display_name":"neurodevelopmental outcomes","score":0.734000027179718},{"id":"https://openalex.org/keywords/neuromonitoring","display_name":"neuromonitoring","score":0.75},{"id":"https://openalex.org/keywords/neuroimaging","display_name":"neuroimaging","score":0.7459999918937683},{"id":"https://openalex.org/keywords/outcome-measurement","display_name":"outcome measurement","score":0.6970000267028809},{"id":"https://openalex.org/keywords/early-intervention","display_name":"early intervention","score":0.6380000114440918},{"id":"https://openalex.org/keywords/pathophysiology","display_name":"pathophysiology","score":0.5989999771118164}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8837000131607056},{"id":"https://openalex.org/C2778621155","wikidata":"https://www.wikidata.org/wiki/Q576349","display_name":"Encephalopathy","level":2,"score":0.7620999813079834},{"id":"https://openalex.org/C2780164069","wikidata":"https://www.wikidata.org/wiki/Q2694437","display_name":"Perinatal asphyxia","level":3,"score":0.7196999788284302},{"id":"https://openalex.org/C2777390192","wikidata":"https://www.wikidata.org/wiki/Q1036696","display_name":"Hypothermia","level":2,"score":0.6107000112533569},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5677000284194946},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.5618000030517578},{"id":"https://openalex.org/C2779914510","wikidata":"https://www.wikidata.org/wiki/Q193840","display_name":"Asphyxia","level":2,"score":0.5153999924659729},{"id":"https://openalex.org/C2778080812","wikidata":"https://www.wikidata.org/wiki/Q5832339","display_name":"Neonatal encephalopathy","level":3,"score":0.46869999170303345},{"id":"https://openalex.org/C2780665704","wikidata":"https://www.wikidata.org/wiki/Q959298","display_name":"Intervention (counseling)","level":2,"score":0.45750001072883606},{"id":"https://openalex.org/C2909832856","wikidata":"https://www.wikidata.org/wiki/Q2249526","display_name":"Hypoxic Ischemic Encephalopathy","level":3,"score":0.4465000033378601},{"id":"https://openalex.org/C3020606620","wikidata":"https://www.wikidata.org/wiki/Q179661","display_name":"Treatment modality","level":2,"score":0.42170000076293945},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.3571000099182129},{"id":"https://openalex.org/C187316915","wikidata":"https://www.wikidata.org/wiki/Q92307203","display_name":"Case fatality rate","level":3,"score":0.29179999232292175},{"id":"https://openalex.org/C2909855758","wikidata":"https://www.wikidata.org/wiki/Q2694437","display_name":"Asphyxia Neonatorum","level":3,"score":0.25920000672340393},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.25870001316070557}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:ojs2.belgjpaediatrics.com:article/17","doi":null,"is_oa":true,"landing_page_url":"https://www.belgjpaediatrics.com/index.php/bjp/article/view/17/201","pdf_url":"https://www.belgjpaediatrics.com/index.php/bjp/article/download/17/201/115","source":{"id":"https://openalex.org/S7407066516","display_name":"Belgian Journal of Paediatrics","issn_l":"2466-8907","issn":["2466-8907","2566-1558"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2466-8907","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:ojs2.belgjpaediatrics.com:article/17","doi":null,"is_oa":true,"landing_page_url":"https://www.belgjpaediatrics.com/index.php/bjp/article/view/17/201","pdf_url":"https://www.belgjpaediatrics.com/index.php/bjp/article/download/17/201/115","source":{"id":"https://openalex.org/S7407066516","display_name":"Belgian Journal of Paediatrics","issn_l":"2466-8907","issn":["2466-8907","2566-1558"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2466-8907","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7215486305.pdf"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4309964264","https://openalex.org/W3215637014","https://openalex.org/W2181910807","https://openalex.org/W2742396310","https://openalex.org/W4322771962","https://openalex.org/W2907498291","https://openalex.org/W2530924370","https://openalex.org/W3096465155","https://openalex.org/W2884194761","https://openalex.org/W2036581922"],"abstract_inverted_index":{"Perinatal":[0,25],"asphyxia":[1,26],"(PA)":[2],"is":[3,19,102],"defined":[4],"as":[5],"the":[6,12,47,55,69,80,105,110,120],"deprivation":[7],"of":[8,14,40,51,82,93,99],"oxygen":[9],"occurring":[10],"around":[11],"time":[13],"birth.":[15],"Hypoxic-ischemic":[16],"encephalopathy":[17,21],"(HIE)":[18],"an":[20],"due":[22],"to":[23,67,103],"PA.":[24],"and":[27,35,72,84,89,95,114,116,125],"HIE":[28,62],"are":[29],"still":[30],"associated":[31],"with":[32,130],"high":[33,131],"morbidity":[34],"mortality":[36,70],"rates.":[37],"The":[38,97],"use":[39],"therapeutic":[41],"hypothermia":[42],"(TH)":[43],"commencing":[44],"preferably":[45],"within":[46],"first":[48],"6":[49],"hours":[50],"life":[52],"\u2013":[53,63],"currently":[54],"only":[56],"scientifically":[57],"validated":[58],"treatment":[59],"modality":[60],"for":[61,112,122,128,133],"has":[64],"been":[65],"proven":[66],"reduce":[68],"rate":[71],"disability.":[73],"We":[74],"discuss":[75],"pathophysiology,":[76],"diagnosis,":[77],"neuroimaging,":[78],"treatment,":[79],"impact":[81],"PA":[83,94],"TH":[85,115],"on":[86],"pharmacology,":[87],"follow-up,":[88],"some":[90],"remaining":[91],"questions":[92],"HIE.":[96],"purpose":[98],"this":[100],"article":[101],"guide":[104],"general":[106],"pediatrician":[107],"in":[108],"selecting":[109],"patients":[111],"neuromonitoring":[113],"inform":[117],"them":[118],"about":[119],"tools":[121],"outcome":[123],"assessment":[124],"early":[126],"intervention":[127],"those":[129],"risk":[132],"impaired":[134],"neurodevelopmental":[135],"outcome.":[136]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2026-10-02T00:00:00"}