{"id":"https://openalex.org/W7215174377","doi":null,"title":"Preparation, Characterization and Evaluation of Biological Activity and Study of Molecular Docking of Some New Thiazolidine Derivatives","display_name":"Preparation, Characterization and Evaluation of Biological Activity and Study of Molecular Docking of Some New Thiazolidine Derivatives","publication_year":2024,"publication_date":"2024-03-27","ids":{"openalex":"https://openalex.org/W7215174377"},"language":"en","primary_location":{"id":"pmh:oai:journal.univerpublishing.org:article/3198","doi":null,"is_oa":true,"landing_page_url":"https://journal.univerpublishing.org/index.php/woscience/article/view/3198","pdf_url":"https://journal.univerpublishing.org/index.php/woscience/article/download/3198/2702","source":{"id":"https://openalex.org/S7407066651","display_name":"World of Science: Journal on Modern Research Methodologies","issn_l":"2835-3072","issn":["2835-3072"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2835-3072","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://journal.univerpublishing.org/index.php/woscience/article/download/3198/2702","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107589879","display_name":"Abdul Wahed Abdul Sattar Talluh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I72539421","display_name":"University of Tikrit","ror":"https://ror.org/01zfzax10","country_code":"IQ","type":"education","lineage":["https://openalex.org/I72539421"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Talluh, Abdul Wahed Abdul Sattar","raw_affiliation_strings":["Tikrit University, College of Basic Education, Shirqat, Tikrit, Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tikrit University, College of Basic Education, Shirqat, Tikrit, Iraq","institution_ids":["https://openalex.org/I72539421"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5116075688","display_name":"Jamil Nadhem Saleh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405257924","display_name":"Ministry of Education","ror":"https://ror.org/05tqgjy81","country_code":"IQ","type":"government","lineage":["https://openalex.org/I4405257924"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Saleh, Jamil Nadhem","raw_affiliation_strings":["Salah Al-Din Education Directorate, Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Salah Al-Din Education Directorate, Iraq","institution_ids":["https://openalex.org/I4405257924"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109791654","display_name":"Mohammed Jwher Saleh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405257924","display_name":"Ministry of Education","ror":"https://ror.org/05tqgjy81","country_code":"IQ","type":"government","lineage":["https://openalex.org/I4405257924"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Saleh, Mohammed Jwher","raw_affiliation_strings":["Salah Al-Din Education Directorate, Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Salah Al-Din Education Directorate, Iraq","institution_ids":["https://openalex.org/I4405257924"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10274","display_name":"Heterocyclic Compound Synthesis and Bioactivity","score":0.5145999789237976,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10274","display_name":"Heterocyclic Compound Synthesis and Bioactivity","score":0.5145999789237976,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14099","display_name":"Synthesis and Characterization of Heterocyclic Compounds","score":0.2969000041484833,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13160","display_name":"Synthesis and Biological Evaluation","score":0.07569999992847443,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thiazolidine-derivatives","display_name":"thiazolidine derivatives","score":0.9950000047683716},{"id":"https://openalex.org/keywords/hydrazones","display_name":"hydrazones","score":0.7910000085830688},{"id":"https://openalex.org/keywords/thioglycolic-acid","display_name":"thioglycolic acid","score":0.9629999995231628},{"id":"https://openalex.org/keywords/zinc-chloride-catalysis","display_name":"zinc chloride catalysis","score":0.8339999914169312},{"id":"https://openalex.org/keywords/pentacyclic-heterocycles","display_name":"pentacyclic heterocycles","score":0.8019999861717224},{"id":"https://openalex.org/keywords/antibacterial-activity","display_name":"antibacterial activity","score":0.8320000171661377},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.9990000128746033},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":1.0},{"id":"https://openalex.org/keywords/molecular-docking","display_name":"molecular docking","score":0.9559999704360962},{"id":"https://openalex.org/keywords/structure-activity-relationship","display_name":"structure-activity relationship","score":0.7310000061988831}],"concepts":[{"id":"https://openalex.org/C2776590680","wikidata":"https://www.wikidata.org/wiki/Q413761","display_name":"Thiazolidine","level":2,"score":0.8766000270843506},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8583999872207642},{"id":"https://openalex.org/C116073593","wikidata":"https://www.wikidata.org/wiki/Q864491","display_name":"Biological activity","level":3,"score":0.579200029373169},{"id":"https://openalex.org/C2779002150","wikidata":"https://www.wikidata.org/wiki/Q414738","display_name":"Thioglycolic acid","level":2,"score":0.5460000038146973},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.4902999997138977},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.4758000075817108},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.46700000762939453},{"id":"https://openalex.org/C2780104969","wikidata":"https://www.wikidata.org/wiki/Q4774530","display_name":"Antibacterial activity","level":3,"score":0.4569000005722046},{"id":"https://openalex.org/C2779448499","wikidata":"https://www.wikidata.org/wiki/Q1227206","display_name":"Oxadiazole","level":2,"score":0.45570001006126404},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.4271000027656555},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.37770000100135803},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.3553999960422516},{"id":"https://openalex.org/C2780349576","wikidata":"https://www.wikidata.org/wiki/Q416007","display_name":"Hydrazone","level":2,"score":0.3490000069141388},{"id":"https://openalex.org/C103319777","wikidata":"https://www.wikidata.org/wiki/Q1979695","display_name":"Proton NMR","level":2,"score":0.3330000042915344},{"id":"https://openalex.org/C2778695967","wikidata":"https://www.wikidata.org/wiki/Q44791900","display_name":"Chloride","level":2,"score":0.3197999894618988},{"id":"https://openalex.org/C178910836","wikidata":"https://www.wikidata.org/wiki/Q2196961","display_name":"Molecular model","level":2,"score":0.30550000071525574},{"id":"https://openalex.org/C14961307","wikidata":"https://www.wikidata.org/wiki/Q5377176","display_name":"Energy minimization","level":2,"score":0.30329999327659607},{"id":"https://openalex.org/C2777604212","wikidata":"https://www.wikidata.org/wiki/Q407944","display_name":"Imide","level":2,"score":0.2874999940395355},{"id":"https://openalex.org/C153642686","wikidata":"https://www.wikidata.org/wiki/Q70906","display_name":"Infrared spectroscopy","level":2,"score":0.2827000021934509},{"id":"https://openalex.org/C3019249092","wikidata":"https://www.wikidata.org/wiki/Q274493","display_name":"Antibacterial agent","level":3,"score":0.27889999747276306},{"id":"https://openalex.org/C41183919","wikidata":"https://www.wikidata.org/wiki/Q423026","display_name":"Active site","level":3,"score":0.2655999958515167},{"id":"https://openalex.org/C2776428424","wikidata":"https://www.wikidata.org/wiki/Q2602701","display_name":"Schiff base","level":2,"score":0.2651999890804291},{"id":"https://openalex.org/C41685203","wikidata":"https://www.wikidata.org/wiki/Q1974042","display_name":"Docking (animal)","level":2,"score":0.2635999917984009},{"id":"https://openalex.org/C66974803","wikidata":"https://www.wikidata.org/wiki/Q10359898","display_name":"Nuclear magnetic resonance spectroscopy","level":2,"score":0.26260000467300415}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:journal.univerpublishing.org:article/3198","doi":null,"is_oa":true,"landing_page_url":"https://journal.univerpublishing.org/index.php/woscience/article/view/3198","pdf_url":"https://journal.univerpublishing.org/index.php/woscience/article/download/3198/2702","source":{"id":"https://openalex.org/S7407066651","display_name":"World of Science: Journal on Modern Research Methodologies","issn_l":"2835-3072","issn":["2835-3072"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2835-3072","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:journal.univerpublishing.org:article/3198","doi":null,"is_oa":true,"landing_page_url":"https://journal.univerpublishing.org/index.php/woscience/article/view/3198","pdf_url":"https://journal.univerpublishing.org/index.php/woscience/article/download/3198/2702","source":{"id":"https://openalex.org/S7407066651","display_name":"World of Science: Journal on Modern Research Methodologies","issn_l":"2835-3072","issn":["2835-3072"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2835-3072","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7215174377.pdf","grobid_xml":"https://content.openalex.org/works/W7215174377.grobid-xml"},"referenced_works_count":7,"referenced_works":["https://openalex.org/W3197020035","https://openalex.org/W3217623343","https://openalex.org/W4210685260","https://openalex.org/W4282913408","https://openalex.org/W4293084539","https://openalex.org/W4297564197","https://openalex.org/W4307941926"],"related_works":["https://openalex.org/W7172453212","https://openalex.org/W7215485292","https://openalex.org/W4308446656","https://openalex.org/W4386652165","https://openalex.org/W4220891371","https://openalex.org/W4388966287","https://openalex.org/W4396520839","https://openalex.org/W2999920615","https://openalex.org/W2596228039","https://openalex.org/W3127212180"],"abstract_inverted_index":{"In":[0],"this":[1],"work,":[2],"equal":[3],"moles":[4],"of":[5,76,94,107],"hydrazone":[6],"base":[7],"derivatives":[8,17],"and":[9,24,37,39,50,55,83],"thioglycolic":[10],"acid":[11],"react":[12],"to":[13,61],"form":[14,106],"pentacyclic":[15],"thiazolidine":[16],"with":[18],"zinc":[19],"chloride":[20],"as":[21,27],"a":[22,28],"catalyst":[23],"using":[25,115],"dioxane":[26],"solvent.":[29],"Proton":[30],"nuclear":[31],"magnetic":[32],"resonance":[33],"spectroscopy,":[34,36],"infrared":[35],"physical":[38],"spectroscopic":[40],"techniques":[41],"have":[42],"confirmed":[43],"the":[44,48,63,74],"complex":[45],"structures.":[46],"Furthermore,":[47],"purity":[49],"melting":[51],"points":[52],"were":[53,101],"determined,":[54],"thin-layer":[56],"chromatography":[57],"(TLC)":[58],"was":[59,113],"used":[60],"track":[62],"reaction":[64],"development.":[65],"The":[66,103],"researchers":[67],"examined":[68],"how":[69],"several":[70],"chemicals":[71],"produced":[72],"affected":[73],"development":[75],"two":[77],"bacterial":[78],"isolates:":[79],"Escherichia":[80],"coli,":[81],"gram-negative,":[82],"Staphylococcus":[84],"aureus,":[85],"gram-positive.":[86],"Using":[87],"MOE":[88],"software":[89],"(2009),":[90],"molecular":[91],"docking":[92],"probes":[93],"compounds":[95],"(AB20,":[96],"AB21)":[97],"against":[98],"E.":[99],"coli":[100],"performed.":[102],"most":[104],"stable":[105],"these":[108],"molecules":[109],"(lowest":[110],"energy":[111,117],"barrier)":[112],"achieved":[114],"an":[116],"minimization":[118],"procedure.":[119]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2026-10-02T00:00:00"}