{"id":"https://openalex.org/W7214955150","doi":"https://doi.org/10.4240/wjgs.124318","title":"Comparative efficacy of bowel preparation strategies in colorectal surgery: A network meta-analysis of randomized controlled trials","display_name":"Comparative efficacy of bowel preparation strategies in colorectal surgery: A network meta-analysis of randomized controlled trials","publication_year":2026,"publication_date":"2026-09-30","ids":{"openalex":"https://openalex.org/W7214955150","doi":"https://doi.org/10.4240/wjgs.124318"},"language":"en","primary_location":{"id":"doi:10.4240/wjgs.124318","doi":"https://doi.org/10.4240/wjgs.124318","is_oa":true,"landing_page_url":"https://doi.org/10.4240/wjgs.124318","pdf_url":"https://www.f6publishing.com/Forms/Main/DownloadFile.aspx?type=m&typeid=2&id=124318&filepath=8E31D0401EB18CD6271A9142AB7E05E351B0026048D472EF9EC020197AA4C56DC210E9244E7BBEA7","source":{"id":"https://openalex.org/S91520407","display_name":"World Journal of Gastrointestinal Surgery","issn_l":"1948-9366","issn":["1948-9366"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315735","host_organization_name":"Baishideng Publishing Group","host_organization_lineage":["https://openalex.org/P4310315735"],"host_organization_lineage_names":["Baishideng Publishing Group"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Gastrointestinal Surgery","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.f6publishing.com/Forms/Main/DownloadFile.aspx?type=m&typeid=2&id=124318&filepath=8E31D0401EB18CD6271A9142AB7E05E351B0026048D472EF9EC020197AA4C56DC210E9244E7BBEA7","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055232728","display_name":"Maha AbuZarifa","orcid":"https://orcid.org/0000-0003-3637-6221","observed_orcids":["https://orcid.org/0000-0003-3637-6221"]},"institutions":[{"id":"https://openalex.org/I21215505","display_name":"Al-Quds University","ror":"https://ror.org/04hym7e04","country_code":"PS","type":"education","lineage":["https://openalex.org/I21215505"]}],"countries":["PS"],"is_corresponding":false,"raw_author_name":"Maha AbuZarifa","raw_affiliation_strings":["Faculty of Medicine , Al-Quds University , Gaza P850 , Palestine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine , Al-Quds University , Gaza P850 , Palestine","institution_ids":["https://openalex.org/I21215505"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5118174559","display_name":"Mesan Hijazy","orcid":"https://orcid.org/0009-0006-3887-0011","observed_orcids":["https://orcid.org/0009-0006-3887-0011"]},"institutions":[{"id":"https://openalex.org/I21215505","display_name":"Al-Quds University","ror":"https://ror.org/04hym7e04","country_code":"PS","type":"education","lineage":["https://openalex.org/I21215505"]}],"countries":["PS"],"is_corresponding":false,"raw_author_name":"Mesan Hijazy","raw_affiliation_strings":["Faculty of Medicine , Al-Quds University , Gaza P850 , Palestine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine , Al-Quds University , Gaza P850 , Palestine","institution_ids":["https://openalex.org/I21215505"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076161524","display_name":"Asmaa Zakria Alnajjar","orcid":"https://orcid.org/0000-0002-1254-4289","observed_orcids":["https://orcid.org/0000-0002-1254-4289"]},"institutions":[{"id":"https://openalex.org/I21215505","display_name":"Al-Quds University","ror":"https://ror.org/04hym7e04","country_code":"PS","type":"education","lineage":["https://openalex.org/I21215505"]}],"countries":["PS"],"is_corresponding":false,"raw_author_name":"Asmaa Zakria Alnajjar","raw_affiliation_strings":["Faculty of Medicine , Al-Quds University , Gaza P850 , Palestine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine , Al-Quds University , Gaza P850 , Palestine","institution_ids":["https://openalex.org/I21215505"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119264894","display_name":"Omar Khaled Abdelsalam","orcid":"https://orcid.org/0009-0005-1609-1036","observed_orcids":["https://orcid.org/0009-0005-1609-1036"]},"institutions":[{"id":"https://openalex.org/I21215505","display_name":"Al-Quds University","ror":"https://ror.org/04hym7e04","country_code":"PS","type":"education","lineage":["https://openalex.org/I21215505"]}],"countries":["PS"],"is_corresponding":false,"raw_author_name":"Omar Khaled Abdelsalam","raw_affiliation_strings":["Faculty of Medicine , Al-Quds University , Gaza P850 , Palestine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine , Al-Quds University , Gaza P850 , Palestine","institution_ids":["https://openalex.org/I21215505"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5125988876","display_name":"Abdalrahman Ajjur","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I21215505","display_name":"Al-Quds University","ror":"https://ror.org/04hym7e04","country_code":"PS","type":"education","lineage":["https://openalex.org/I21215505"]}],"countries":["PS"],"is_corresponding":false,"raw_author_name":"Abdalrahman Ajjur","raw_affiliation_strings":["Faculty of Medicine , Al-Quds University , Gaza P850 , Palestine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine , Al-Quds University , Gaza P850 , Palestine","institution_ids":["https://openalex.org/I21215505"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073037129","display_name":"Mariam A Abu Salah","orcid":"https://orcid.org/0009-0006-1007-5550","observed_orcids":["https://orcid.org/0009-0006-1007-5550"]},"institutions":[{"id":"https://openalex.org/I21215505","display_name":"Al-Quds University","ror":"https://ror.org/04hym7e04","country_code":"PS","type":"education","lineage":["https://openalex.org/I21215505"]}],"countries":["PS"],"is_corresponding":false,"raw_author_name":"Mariam A Abusalah","raw_affiliation_strings":["Faculty of Medicine , Al-Quds University , Gaza P850 , Palestine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine , Al-Quds University , Gaza P850 , Palestine","institution_ids":["https://openalex.org/I21215505"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5153650341","display_name":"Abdallah AbuJlambo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I21215505","display_name":"Al-Quds University","ror":"https://ror.org/04hym7e04","country_code":"PS","type":"education","lineage":["https://openalex.org/I21215505"]}],"countries":["PS"],"is_corresponding":false,"raw_author_name":"Abdallah AbuJlambo","raw_affiliation_strings":["Faculty of Medicine , Al-Quds University , Gaza P850 , Palestine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine , Al-Quds University , Gaza P850 , Palestine","institution_ids":["https://openalex.org/I21215505"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5117690190","display_name":"Mohammed B. AbuZarifa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I21215505","display_name":"Al-Quds University","ror":"https://ror.org/04hym7e04","country_code":"PS","type":"education","lineage":["https://openalex.org/I21215505"]}],"countries":["PS"],"is_corresponding":false,"raw_author_name":"Mohammed B AbuZarifa","raw_affiliation_strings":["Faculty of Medicine , Al-Quds University , Gaza P850 , Palestine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine , Al-Quds University , Gaza P850 , Palestine","institution_ids":["https://openalex.org/I21215505"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5153670519","display_name":"Ola AbuZarifa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I21215505","display_name":"Al-Quds University","ror":"https://ror.org/04hym7e04","country_code":"PS","type":"education","lineage":["https://openalex.org/I21215505"]}],"countries":["PS"],"is_corresponding":false,"raw_author_name":"Ola AbuZarifa","raw_affiliation_strings":["Faculty of Medicine , Al-Quds University , Gaza P850 , Palestine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine , Al-Quds University , Gaza P850 , Palestine","institution_ids":["https://openalex.org/I21215505"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5153640783","display_name":"Hazem Ayesh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hazem Ayesh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11080","display_name":"Surgical site infection prevention","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11080","display_name":"Surgical site infection prevention","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12020","display_name":"Enhanced Recovery After Surgery","score":0.020400000736117363,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bowel-preparation","display_name":"bowel preparation","score":0.9779999852180481},{"id":"https://openalex.org/keywords/colorectal-surgery","display_name":"colorectal surgery","score":0.949999988079071},{"id":"https://openalex.org/keywords/mechanical-bowel-preparation","display_name":"mechanical bowel preparation","score":0.968999981880188},{"id":"https://openalex.org/keywords/oral-antibiotics","display_name":"oral antibiotics","score":0.9660000205039978},{"id":"https://openalex.org/keywords/surgical-site-infection","display_name":"surgical site infection","score":0.9670000076293945},{"id":"https://openalex.org/keywords/anastomotic-leakage","display_name":"anastomotic leakage","score":0.8920000195503235},{"id":"https://openalex.org/keywords/postoperative-ileus","display_name":"postoperative ileus","score":0.9890000224113464},{"id":"https://openalex.org/keywords/clavien-dindo-classification","display_name":"Clavien-Dindo classification","score":0.8180000185966492},{"id":"https://openalex.org/keywords/postoperative-complications","display_name":"postoperative complications","score":0.8679999709129333},{"id":"https://openalex.org/keywords/infection-control","display_name":"infection control","score":0.42399999499320984}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9405999779701233},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.7271000146865845},{"id":"https://openalex.org/C3019222653","wikidata":"https://www.wikidata.org/wiki/Q194517","display_name":"Bowel preparation","level":5,"score":0.5911999940872192},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5705000162124634},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46129998564720154},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.37290000915527344},{"id":"https://openalex.org/C204243189","wikidata":"https://www.wikidata.org/wiki/Q1363085","display_name":"Randomization","level":3,"score":0.34200000762939453},{"id":"https://openalex.org/C2778260677","wikidata":"https://www.wikidata.org/wiki/Q917447","display_name":"Inflammatory bowel disease","level":3,"score":0.301800012588501},{"id":"https://openalex.org/C2778435480","wikidata":"https://www.wikidata.org/wiki/Q840387","display_name":"Colonoscopy","level":4,"score":0.29010000824928284},{"id":"https://openalex.org/C523026621","wikidata":"https://www.wikidata.org/wiki/Q1413084","display_name":"Colorectal surgery","level":3,"score":0.28679999709129333},{"id":"https://openalex.org/C202953159","wikidata":"https://www.wikidata.org/wiki/Q382695","display_name":"Intention-to-treat analysis","level":3,"score":0.28060001134872437},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.27160000801086426}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.4240/wjgs.124318","doi":"https://doi.org/10.4240/wjgs.124318","is_oa":true,"landing_page_url":"https://doi.org/10.4240/wjgs.124318","pdf_url":"https://www.f6publishing.com/Forms/Main/DownloadFile.aspx?type=m&typeid=2&id=124318&filepath=8E31D0401EB18CD6271A9142AB7E05E351B0026048D472EF9EC020197AA4C56DC210E9244E7BBEA7","source":{"id":"https://openalex.org/S91520407","display_name":"World Journal of Gastrointestinal Surgery","issn_l":"1948-9366","issn":["1948-9366"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315735","host_organization_name":"Baishideng Publishing Group","host_organization_lineage":["https://openalex.org/P4310315735"],"host_organization_lineage_names":["Baishideng Publishing Group"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Gastrointestinal Surgery","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.4240/wjgs.124318","doi":"https://doi.org/10.4240/wjgs.124318","is_oa":true,"landing_page_url":"https://doi.org/10.4240/wjgs.124318","pdf_url":"https://www.f6publishing.com/Forms/Main/DownloadFile.aspx?type=m&typeid=2&id=124318&filepath=8E31D0401EB18CD6271A9142AB7E05E351B0026048D472EF9EC020197AA4C56DC210E9244E7BBEA7","source":{"id":"https://openalex.org/S91520407","display_name":"World Journal of Gastrointestinal Surgery","issn_l":"1948-9366","issn":["1948-9366"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315735","host_organization_name":"Baishideng Publishing Group","host_organization_lineage":["https://openalex.org/P4310315735"],"host_organization_lineage_names":["Baishideng Publishing Group"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Gastrointestinal Surgery","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7214955150.pdf","grobid_xml":"https://content.openalex.org/works/W7214955150.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W1525587965","https://openalex.org/W1952011450","https://openalex.org/W2010699829","https://openalex.org/W2012720534","https://openalex.org/W2013483939","https://openalex.org/W2070768273","https://openalex.org/W2079556948","https://openalex.org/W2091808438","https://openalex.org/W2111999709","https://openalex.org/W2118200595","https://openalex.org/W2147166052","https://openalex.org/W2147663830","https://openalex.org/W2274035750","https://openalex.org/W2559501430","https://openalex.org/W2766647512","https://openalex.org/W2771390534","https://openalex.org/W2801524727","https://openalex.org/W2898036058","https://openalex.org/W2904014522","https://openalex.org/W2907424462","https://openalex.org/W2970684805","https://openalex.org/W2990261978","https://openalex.org/W3015163167","https://openalex.org/W3118615836","https://openalex.org/W4211229530","https://openalex.org/W4236300497","https://openalex.org/W4254922884","https://openalex.org/W4313816769","https://openalex.org/W4362604464","https://openalex.org/W4378782600","https://openalex.org/W4378952867","https://openalex.org/W4390104570","https://openalex.org/W4391947155","https://openalex.org/W4392986189","https://openalex.org/W4396873264","https://openalex.org/W4402210287","https://openalex.org/W4412427792"],"related_works":["https://openalex.org/W4283386117","https://openalex.org/W2898036058","https://openalex.org/W4245412626","https://openalex.org/W4378902648","https://openalex.org/W3205431047","https://openalex.org/W4412727371","https://openalex.org/W4281670798","https://openalex.org/W3135616783","https://openalex.org/W2766647512","https://openalex.org/W4378782600"],"abstract_inverted_index":{"BACKGROUND":[0],"Colorectal":[1],"surgeries":[2],"are":[3,9],"commonly":[4],"performed":[5],"procedures,":[6],"yet":[7],"they":[8,194],"associated":[10],"with":[11,83,93,154,167,229],"a":[12,84,155,168,178,235,246],"considerable":[13],"risk":[14,157,170],"of":[15,48,71,146,158,171,208,249],"complications":[16,56],"such":[17],"as":[18,215],"surgical":[19,250],"site":[20],"infections":[21],"(SSIs)":[22],"and":[23,32,44,73,98,122,132,148,164,193,210],"anastomotic":[24,128],"leaks.Preoperative":[25],"approaches,":[26],"including":[27],"mechanical":[28],"bowel":[29,50],"preparation":[30,51],"(MBP)":[31],"oral":[33],"antibiotics":[34],"(OAB),":[35],"aim":[36],"to":[37,76,89,111,189,245],"reduce":[38],"these":[39],"risks.AIM":[40],"To":[41],"comprehensively":[42],"evaluate":[43,112],"compare":[45],"the":[46,113,116,144,182,190,197,206,216],"efficacy":[47],"various":[49],"approaches":[52],"in":[53,66,105,115,227],"reducing":[54],"postoperative":[55,130,222],"following":[57],"colorectal":[58],"surgery.METHODS":[59],"A":[60],"thorough":[61],"literature":[62],"search":[63],"was":[64,87,109],"conducted":[65,138],"PubMed,":[67],"Cochrane":[68],"Library,":[69],"Web":[70],"Science,":[72],"Scopus":[74],"up":[75],"April":[77],"28,":[78],"2025.A":[79],"frequentist":[80],"network":[81],"meta-analysis":[82],"random-effects":[85],"model":[86],"used":[88,110],"calculate":[90],"relative":[91,156,169],"risks":[92],"95%":[94],"confidence":[95,114],"intervals":[96],"(CIs),":[97],"interventions":[99],"were":[100],"ranked":[101],"using":[102],"P":[103,199],"scores.Confidence":[104],"Network":[106],"Meta-Analysis":[107],"assessment":[108],"evidence.Primary":[117],"outcomes":[118,126],"included":[119],"incisional":[120,152],"SSI":[121,153,166],"organ":[123],"space":[124],"SSI.Secondary":[125],"encompassed":[127],"leakage,":[129],"ileus,":[131],"Clavien-Dindo":[133],"I-II":[134],"complications.":[135],"RESULTSOur":[136],"analysis,":[137],"on":[139],"38":[140],"studies,":[141],"showed":[142,187],"that":[143,240],"combination":[145,207],"MBP":[147,209],"OAB":[149,211],"considerably":[150],"reduced":[151],"0.53":[159],"(95%CI:":[160,173],"0.29-0.99,P":[161],"=":[162,175],"0.04)":[163],"organ-space":[165],"0.62":[172],"0.39-0.99,P":[174],"0.04),":[176],"demonstrating":[177],"statistically":[179],"significant":[180],"effect.In":[181],"secondary":[183],"outcomes,":[184],"OAB-containing":[185],"regimens":[186],"superiority":[188],"other":[191],"treatments,":[192],"also":[195,233],"had":[196],"highest":[198],"score.":[200],"CONCLUSION":[201],"4":[202],"/":[203],"30Even":[204],"though":[205],"is":[212],"strongly":[213],"supported":[214],"preferred":[217],"strategy":[218],"for":[219,237],"preventing":[220],"infectious":[221],"complications.These":[223],"findings":[224],"not":[225],"only":[226],"line":[228],"current":[230],"recommendations":[231],"but":[232],"provide":[234],"foundation":[236],"additional":[238],"research":[239],"will":[241],"investigate":[242],"their":[243],"relevance":[244],"larger":[247],"variety":[248],"procedures.":[251]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-10-01T00:00:00"}