{"id":"https://openalex.org/W7214929772","doi":"https://doi.org/10.1002/rcr2.70774","title":"Environmental Asbestos Exposure as a Possible Pathway to Early\u2010Onset Pleural Mesothelioma: A Case From Afghanistan and Pakistan to London","display_name":"Environmental Asbestos Exposure as a Possible Pathway to Early\u2010Onset Pleural Mesothelioma: A Case From Afghanistan and Pakistan to London","publication_year":2026,"publication_date":"2026-09-30","ids":{"openalex":"https://openalex.org/W7214929772","doi":"https://doi.org/10.1002/rcr2.70774","pmid":"https://pubmed.ncbi.nlm.nih.gov/42823995","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13626864"},"language":"en","primary_location":{"id":"doi:10.1002/rcr2.70774","doi":"https://doi.org/10.1002/rcr2.70774","is_oa":true,"landing_page_url":"https://doi.org/10.1002/rcr2.70774","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/rcr2.70774","source":{"id":"https://openalex.org/S2764822511","display_name":"Respirology Case Reports","issn_l":"2051-3380","issn":["2051-3380"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respirology Case Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/rcr2.70774","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064577290","display_name":"Sophie Mounouchos","orcid":"https://orcid.org/0009-0006-0774-0716","observed_orcids":["https://orcid.org/0009-0006-0774-0716"]},"institutions":[{"id":"https://openalex.org/I4210112187","display_name":"Homerton University Hospital NHS Foundation Trust","ror":"https://ror.org/01zpp3d44","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210112187"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sophie Mounouchos","raw_affiliation_strings":["Homerton NHS Healthcare Trust  London UK"],"raw_orcid":"https://orcid.org/0009-0006-0774-0716","affiliations":[{"raw_affiliation_string":"Homerton NHS Healthcare Trust  London UK","institution_ids":["https://openalex.org/I4210112187"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5153596359","display_name":"Asmita Aggarwal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Asmita Aggarwal","raw_affiliation_strings":["University College London, Respiratory Medicine  London UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University College London, Respiratory Medicine  London UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091153225","display_name":"Asaad Ahmed Nafees","orcid":"https://orcid.org/0000-0001-8174-1625","observed_orcids":["https://orcid.org/0000-0001-8174-1625"]},"institutions":[{"id":"https://openalex.org/I118185606","display_name":"Aga Khan University","ror":"https://ror.org/03gd0dm95","country_code":"PK","type":"education","lineage":["https://openalex.org/I118185606","https://openalex.org/I4210114929"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Asaad Ahmed Nafees","raw_affiliation_strings":["Department of Community Health Sciences Aga Khan University  Karachi Pakistan"],"raw_orcid":"https://orcid.org/0000-0001-8174-1625","affiliations":[{"raw_affiliation_string":"Department of Community Health Sciences Aga Khan University  Karachi Pakistan","institution_ids":["https://openalex.org/I118185606"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021991283","display_name":"Emma J. Johnson","orcid":"https://orcid.org/0000-0003-1940-2280","observed_orcids":["https://orcid.org/0000-0003-1940-2280"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Emma Johnson","raw_affiliation_strings":["Imperial College London  London UK"],"raw_orcid":"https://orcid.org/0000-0003-1940-2280","affiliations":[{"raw_affiliation_string":"Imperial College London  London UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052981042","display_name":"Paul Cullinan","orcid":"https://orcid.org/0000-0002-9314-6468","observed_orcids":["https://orcid.org/0000-0002-9314-6468"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paul Cullinan","raw_affiliation_strings":["London Centre for Work and Health  London UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"London Centre for Work and Health  London UK","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5153616057","display_name":"Carl Reynolds","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210112187","display_name":"Homerton University Hospital NHS Foundation Trust","ror":"https://ror.org/01zpp3d44","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210112187"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Carl Reynolds","raw_affiliation_strings":["Homerton NHS Healthcare Trust  London UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Homerton NHS Healthcare Trust  London UK","institution_ids":["https://openalex.org/I4210112187"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5153616057"],"corresponding_institution_ids":["https://openalex.org/I4210112187"],"apc_list":{"value":1130,"currency":"USD","value_usd":1130},"apc_paid":{"value":1130,"currency":"USD","value_usd":1130},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":"10","first_page":"e70774","last_page":"e70774"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11026","display_name":"Occupational and environmental lung diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11026","display_name":"Occupational and environmental lung diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14168","display_name":"Occupational Health and Global Justice","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3306","display_name":"Health"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10870","display_name":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/malignant-pleural-mesothelioma","display_name":"malignant pleural mesothelioma","score":0.9900000095367432},{"id":"https://openalex.org/keywords/environmental-asbestos-exposure","display_name":"environmental asbestos exposure","score":0.9800000190734863},{"id":"https://openalex.org/keywords/childhood-migration","display_name":"childhood migration","score":0.4180000126361847},{"id":"https://openalex.org/keywords/pleural-effusion","display_name":"pleural effusion","score":0.699999988079071},{"id":"https://openalex.org/keywords/epithelioid-mesothelioma","display_name":"epithelioid mesothelioma","score":0.9279999732971191},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.6729999780654907},{"id":"https://openalex.org/keywords/afghanistan","display_name":"Afghanistan","score":0.574999988079071},{"id":"https://openalex.org/keywords/pakistan","display_name":"Pakistan","score":0.9900000095367432}],"concepts":[{"id":"https://openalex.org/C510490043","wikidata":"https://www.wikidata.org/wiki/Q104085","display_name":"Asbestos","level":2,"score":0.9484999775886536},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.890500009059906},{"id":"https://openalex.org/C2777407522","wikidata":"https://www.wikidata.org/wiki/Q1077603","display_name":"Mesothelioma","level":2,"score":0.7196000218391418},{"id":"https://openalex.org/C2776762749","wikidata":"https://www.wikidata.org/wiki/Q664174","display_name":"Asbestosis","level":3,"score":0.6064000129699707},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.557699978351593},{"id":"https://openalex.org/C2908765410","wikidata":"https://www.wikidata.org/wiki/Q10634401","display_name":"Pleural thickening","level":3,"score":0.5169000029563904},{"id":"https://openalex.org/C2987845665","wikidata":"https://www.wikidata.org/wiki/Q17072363","display_name":"Occupational exposure","level":2,"score":0.47780001163482666},{"id":"https://openalex.org/C2779634585","wikidata":"https://www.wikidata.org/wiki/Q1334541","display_name":"Pleural effusion","level":2,"score":0.4595000147819519},{"id":"https://openalex.org/C544855455","wikidata":"https://www.wikidata.org/wiki/Q1070952","display_name":"Histopathology","level":2,"score":0.44510000944137573},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.362199991941452},{"id":"https://openalex.org/C2776517811","wikidata":"https://www.wikidata.org/wiki/Q7204732","display_name":"Pleural disease","level":4,"score":0.3231000006198883},{"id":"https://openalex.org/C3020547009","wikidata":"https://www.wikidata.org/wiki/Q1070952","display_name":"Histopathological examination","level":2,"score":0.3107999861240387},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.2865000069141388},{"id":"https://openalex.org/C3020807102","wikidata":"https://www.wikidata.org/wiki/Q5060555","display_name":"Farm workers","level":3,"score":0.2531000077724457}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1002/rcr2.70774","doi":"https://doi.org/10.1002/rcr2.70774","is_oa":true,"landing_page_url":"https://doi.org/10.1002/rcr2.70774","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/rcr2.70774","source":{"id":"https://openalex.org/S2764822511","display_name":"Respirology Case Reports","issn_l":"2051-3380","issn":["2051-3380"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respirology Case Reports","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13626864","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13626864/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13626864/pdf/RCR2-14-e70774.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respirol Case Rep","raw_type":"Text"},{"id":"pmid:42823995","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42823995","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respirology case reports","raw_type":"Journal Article"},{"id":"pmh:oai:ecommons.aku.edu:pakistan_fhs_mc_chs_chs-2339","doi":null,"is_oa":false,"landing_page_url":"https://ecommons.aku.edu/pakistan_fhs_mc_chs_chs/1340","pdf_url":null,"source":{"id":"https://openalex.org/S4377196301","display_name":"eCommons - AKU (Aga Khan University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I118185606","host_organization_name":"Aga Khan University","host_organization_lineage":["https://openalex.org/I118185606"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Community Health Sciences","raw_type":"article"},{"id":"pmh:oai:doaj.org/article:23c4365b5d5348d59178280ad7b0e402","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/23c4365b5d5348d59178280ad7b0e402","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Respirology Case Reports, Vol 14, Iss 10, Pp n/a-n/a (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1002/rcr2.70774","doi":"https://doi.org/10.1002/rcr2.70774","is_oa":true,"landing_page_url":"https://doi.org/10.1002/rcr2.70774","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/rcr2.70774","source":{"id":"https://openalex.org/S2764822511","display_name":"Respirology Case Reports","issn_l":"2051-3380","issn":["2051-3380"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respirology Case Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7214929772.pdf","grobid_xml":"https://content.openalex.org/works/W7214929772.grobid-xml"},"referenced_works_count":8,"referenced_works":["https://openalex.org/W2007541023","https://openalex.org/W2054353986","https://openalex.org/W2171104276","https://openalex.org/W2620736592","https://openalex.org/W2759403827","https://openalex.org/W2806103948","https://openalex.org/W2905918618","https://openalex.org/W3201306276"],"related_works":["https://openalex.org/W1970826258","https://openalex.org/W1575821952","https://openalex.org/W2767048405","https://openalex.org/W2016754333","https://openalex.org/W3199380111","https://openalex.org/W1993190017","https://openalex.org/W2415311867","https://openalex.org/W2534564653","https://openalex.org/W7219167627","https://openalex.org/W2905918618"],"abstract_inverted_index":{"Malignant":[0],"pleural":[1,52],"mesothelioma":[2],"(MPM)":[3],"is":[4,30],"strongly":[5],"associated":[6],"with":[7,24,44,67,76,113,128],"occupational":[8,82],"asbestos":[9,97,116,133],"exposure":[10,26],"and":[11,27,48,71,89],"typically":[12],"presents":[13],"decades":[14],"after":[15],"exposure,":[16,83,117],"in":[17,42,74,86,119],"older":[18],"men.":[19],"The":[20],"association":[21],"of":[22,37,63,95,103,109,126],"MPM":[23,129],"environmental":[25,96,104,115],"genetic":[28],"susceptibility":[29],"less":[31],"recognised.":[32],"We":[33],"report":[34],"a":[35,38,49,107],"case":[36],"40-year-old":[39],"man":[40],"presenting":[41],"London":[43],"dyspnoea,":[45],"weight":[46],"loss":[47],"persistent":[50],"right-sided":[51],"effusion":[53],"following":[54],"hospitalisation":[55],"for":[56],"pneumonia.":[57],"Imaging":[58],"showed":[59],"circumferential":[60],"nodular":[61],"thickening":[62],"the":[64],"right":[65],"pleura":[66],"lymph":[68],"node":[69],"involvement,":[70],"histopathology":[72],"was":[73],"keeping":[75],"epithelioid-type":[77],"MPM.":[78],"With":[79],"no":[80],"known":[81],"childhood":[84],"residences":[85],"Kabul,":[87],"Afghanistan":[88],"Peshawar,":[90],"Pakistan,":[91],"where":[92],"high":[93,114],"levels":[94],"are":[98],"documented,":[99],"represent":[100],"plausible":[101],"sources":[102],"exposure.":[105,134],"As":[106],"result":[108],"migration":[110],"from":[111],"regions":[112],"clinicians":[118],"high-income":[120],"countries":[121],"may":[122],"encounter":[123],"increasing":[124],"numbers":[125],"patients":[127],"due":[130],"to":[131],"non-occupational":[132]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-10-01T00:00:00"}