{"id":"https://openalex.org/W7214784607","doi":"https://doi.org/10.5114/pja.2026.164983","title":"Comparison of subcutaneous (SCIT) and sublingual (SLIT) immunotherapy in allergic rhinitis and allergic asthma","display_name":"Comparison of subcutaneous (SCIT) and sublingual (SLIT) immunotherapy in allergic rhinitis and allergic asthma","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7214784607","doi":"https://doi.org/10.5114/pja.2026.164983"},"language":"en","primary_location":{"id":"doi:10.5114/pja.2026.164983","doi":"https://doi.org/10.5114/pja.2026.164983","is_oa":true,"landing_page_url":"https://doi.org/10.5114/pja.2026.164983","pdf_url":"https://www.termedia.pl/Journal/-123/pdf-58684-10?filename=PJA-Comparison.pdf","source":{"id":"https://openalex.org/S2764848368","display_name":"Alergologia Polska - Polish Journal of Allergology","issn_l":"2353-3854","issn":["2353-3854","2391-6052"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alergologia Polska - Polish Journal of Allergology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.termedia.pl/Journal/-123/pdf-58684-10?filename=PJA-Comparison.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5137508953","display_name":"Adam Perek","orcid":"https://orcid.org/0009-0007-5992-5971","observed_orcids":["https://orcid.org/0009-0007-5992-5971"]},"institutions":[{"id":"https://openalex.org/I4210105037","display_name":"Wojew\u00f3dzki Szpital Specjalistyczny nr 5 im. \u015bw. Barbary w Sosnowcu","ror":"https://ror.org/01bdg0p84","country_code":"PL","type":"healthcare","lineage":["https://openalex.org/I4210105037"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Adam Perek","raw_affiliation_strings":["St. Barbara Provincial Specialist Hospital No. 5 , Sosnowiec , Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St. Barbara Provincial Specialist Hospital No. 5 , Sosnowiec , Poland","institution_ids":["https://openalex.org/I4210105037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5125439296","display_name":"Julia Raszewska","orcid":"https://orcid.org/0009-0001-5828-374X","observed_orcids":["https://orcid.org/0009-0001-5828-374X"]},"institutions":[{"id":"https://openalex.org/I4210105037","display_name":"Wojew\u00f3dzki Szpital Specjalistyczny nr 5 im. \u015bw. Barbary w Sosnowcu","ror":"https://ror.org/01bdg0p84","country_code":"PL","type":"healthcare","lineage":["https://openalex.org/I4210105037"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Julia Raszewska","raw_affiliation_strings":["St. Barbara Provincial Specialist Hospital No. 5 , Sosnowiec , Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St. Barbara Provincial Specialist Hospital No. 5 , Sosnowiec , Poland","institution_ids":["https://openalex.org/I4210105037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5137482215","display_name":"Wiktor Jab\u0142o\u0144ski","orcid":"https://orcid.org/0000-0001-9357-8650","observed_orcids":["https://orcid.org/0000-0001-9357-8650"]},"institutions":[{"id":"https://openalex.org/I4210105037","display_name":"Wojew\u00f3dzki Szpital Specjalistyczny nr 5 im. \u015bw. Barbary w Sosnowcu","ror":"https://ror.org/01bdg0p84","country_code":"PL","type":"healthcare","lineage":["https://openalex.org/I4210105037"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Wiktor Jab\u0142o\u0144ski","raw_affiliation_strings":["St. Barbara Provincial Specialist Hospital No. 5 , Sosnowiec , Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St. Barbara Provincial Specialist Hospital No. 5 , Sosnowiec , Poland","institution_ids":["https://openalex.org/I4210105037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133766243","display_name":"Klaudia Kapelka","orcid":"https://orcid.org/0009-0002-5579-9852","observed_orcids":["https://orcid.org/0009-0002-5579-9852"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Klaudia Kapelka","raw_affiliation_strings":["Blessed Virgin Mary Provincial Specialist Hospital , Czestochowa , Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blessed Virgin Mary Provincial Specialist Hospital , Czestochowa , Poland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5126250406","display_name":"Gabriel Mandera","orcid":"https://orcid.org/0009-0005-4803-8723","observed_orcids":["https://orcid.org/0009-0005-4803-8723"]},"institutions":[{"id":"https://openalex.org/I4210105037","display_name":"Wojew\u00f3dzki Szpital Specjalistyczny nr 5 im. \u015bw. Barbary w Sosnowcu","ror":"https://ror.org/01bdg0p84","country_code":"PL","type":"healthcare","lineage":["https://openalex.org/I4210105037"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Gabriel Mandera","raw_affiliation_strings":["St. Barbara Provincial Specialist Hospital No. 5 , Sosnowiec , Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St. Barbara Provincial Specialist Hospital No. 5 , Sosnowiec , Poland","institution_ids":["https://openalex.org/I4210105037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5137480033","display_name":"Karolina Pyrtek","orcid":"https://orcid.org/0000-0003-3054-8133","observed_orcids":["https://orcid.org/0000-0003-3054-8133"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Karolina Pyrtek","raw_affiliation_strings":["District Hospital , Zawiercie , Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"District Hospital , Zawiercie , Poland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109671415","display_name":"Julia \u015awierczek","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Julia \u015awierczek","raw_affiliation_strings":["KKS Statistics , Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"KKS Statistics , Poland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093651509","display_name":"Weronika Targosz","orcid":"https://orcid.org/0009-0007-6069-2669","observed_orcids":["https://orcid.org/0009-0007-6069-2669"]},"institutions":[{"id":"https://openalex.org/I4210105037","display_name":"Wojew\u00f3dzki Szpital Specjalistyczny nr 5 im. \u015bw. Barbary w Sosnowcu","ror":"https://ror.org/01bdg0p84","country_code":"PL","type":"healthcare","lineage":["https://openalex.org/I4210105037"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Weronika Targosz","raw_affiliation_strings":["Barbara Provincial Specialist Hospital No. 5 , Sosnowiec , Poland,","KKS Statistics , Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Barbara Provincial Specialist Hospital No. 5 , Sosnowiec , Poland,","institution_ids":["https://openalex.org/I4210105037"]},{"raw_affiliation_string":"KKS Statistics , Poland","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5138276543","display_name":"Dawid Soba\u0144ski","orcid":"https://orcid.org/0009-0009-5339-7754","observed_orcids":["https://orcid.org/0009-0009-5339-7754"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dawid Soba\u0144ski","raw_affiliation_strings":["Greater Poland Specialist Centre , Provincial Hospital , Poznan , Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Greater Poland Specialist Centre , Provincial Hospital , Poznan , Poland","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/allergen-immunotherapy","display_name":"allergen immunotherapy","score":0.9179999828338623},{"id":"https://openalex.org/keywords/subcutaneous-immunotherapy","display_name":"subcutaneous immunotherapy","score":0.9909999966621399},{"id":"https://openalex.org/keywords/sublingual-immunotherapy","display_name":"sublingual immunotherapy","score":1.0},{"id":"https://openalex.org/keywords/allergic-rhinitis","display_name":"allergic rhinitis","score":1.0},{"id":"https://openalex.org/keywords/allergic-asthma","display_name":"allergic asthma","score":1.0},{"id":"https://openalex.org/keywords/treatment-adherence","display_name":"medication adherence","score":0.8700000047683716},{"id":"https://openalex.org/keywords/immunotherapy-safety","display_name":"immunotherapy safety","score":0.7919999957084656},{"id":"https://openalex.org/keywords/cost-effectiveness","display_name":"cost-effectiveness","score":0.7879999876022339},{"id":"https://openalex.org/keywords/health-care-costs","display_name":"health care costs","score":0.9490000009536743},{"id":"https://openalex.org/keywords/disease-modifying-effects","display_name":"disease-modifying effects","score":0.6729999780654907}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9186999797821045},{"id":"https://openalex.org/C3020633164","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Allergic asthma","level":3,"score":0.72079998254776},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.6140999794006348},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5458999872207642},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.5205000042915344},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.35929998755455017},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.35010001063346863},{"id":"https://openalex.org/C2780648854","wikidata":"https://www.wikidata.org/wiki/Q2745824","display_name":"Immunopathology","level":2,"score":0.34700000286102295},{"id":"https://openalex.org/C2777037608","wikidata":"https://www.wikidata.org/wiki/Q1641412","display_name":"Sublingual immunotherapy","level":4,"score":0.3361999988555908},{"id":"https://openalex.org/C2910900810","wikidata":"https://www.wikidata.org/wiki/Q5941165","display_name":"Respiratory Hypersensitivity","level":3,"score":0.2784000039100647},{"id":"https://openalex.org/C2779779143","wikidata":"https://www.wikidata.org/wiki/Q3493547","display_name":"Desensitization (medicine)","level":3,"score":0.2624000012874603},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.2549999952316284}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.5114/pja.2026.164983","doi":"https://doi.org/10.5114/pja.2026.164983","is_oa":true,"landing_page_url":"https://doi.org/10.5114/pja.2026.164983","pdf_url":"https://www.termedia.pl/Journal/-123/pdf-58684-10?filename=PJA-Comparison.pdf","source":{"id":"https://openalex.org/S2764848368","display_name":"Alergologia Polska - Polish Journal of Allergology","issn_l":"2353-3854","issn":["2353-3854","2391-6052"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alergologia Polska - Polish Journal of Allergology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.5114/pja.2026.164983","doi":"https://doi.org/10.5114/pja.2026.164983","is_oa":true,"landing_page_url":"https://doi.org/10.5114/pja.2026.164983","pdf_url":"https://www.termedia.pl/Journal/-123/pdf-58684-10?filename=PJA-Comparison.pdf","source":{"id":"https://openalex.org/S2764848368","display_name":"Alergologia Polska - Polish Journal of Allergology","issn_l":"2353-3854","issn":["2353-3854","2391-6052"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alergologia Polska - Polish Journal of Allergology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7214784607.pdf","grobid_xml":"https://content.openalex.org/works/W7214784607.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7127586491","https://openalex.org/W2055235518","https://openalex.org/W3179430810","https://openalex.org/W3209624562","https://openalex.org/W3034408594","https://openalex.org/W2969524759","https://openalex.org/W7221669333","https://openalex.org/W4391363363","https://openalex.org/W1971110885","https://openalex.org/W2328057844"],"abstract_inverted_index":{"Allergic":[0],"rhinitis":[1],"and":[2,18,59,79,92,94,99,108,135,153,180,202,210,229],"allergic":[3,44,106,127],"asthma":[4,122],"are":[5,182],"among":[6],"the":[7,34,40,53,109,164],"most":[8,165],"prevalent":[9],"chronic":[10],"diseases,":[11],"significantly":[12],"impairing":[13],"patients'":[14],"quality":[15],"of":[16,38,43,47,62,72,121,133,139,163,168,214],"life":[17],"generating":[19],"substantial":[20],"healthcare":[21,96,199,230],"costs.Allergen":[22],"immunotherapy":[23],"(AIT),":[24],"administered":[25],"as":[26],"subcutaneous":[27],"(SCIT)":[28],"or":[29],"sublingual":[30],"(SLIT)":[31],"immunotherapy,":[32],"remains":[33,161],"only":[35],"treatment":[36,88,155,187],"capable":[37],"modifying":[39],"natural":[41],"course":[42],"disease.The":[45],"aim":[46],"this":[48],"study":[49],"was":[50,82],"to":[51,196,222],"compare":[52],"clinical":[54,74,170],"efficacy,":[55,142],"safety":[56,151,227],"profile,":[57,226],"adherence,":[58,91],"economic":[60],"aspects":[61],"both":[63,173,178],"AIT":[64,215],"modalities":[65],"based":[66],"on":[67,87],"current":[68],"evidence.A":[69],"narrative":[70],"review":[71],"randomised":[73],"trials,":[75],"meta-analyses,":[76],"observational":[77],"studies,":[78],"pharmacoeconomic":[80],"analyses":[81,175],"conducted,":[83],"with":[84,114,126,185,194,206],"particular":[85],"emphasis":[86],"effectiveness,":[89],"safety,":[90],"direct":[93],"indirect":[95,203],"costs.Both":[97],"SCIT":[98,179],"SLIT":[100,144,181],"demonstrate":[101],"significant":[102],"efficacy":[103],"in":[104,124],"reducing":[105],"symptoms":[107],"need":[110],"for":[111,172],"symptomatic":[112,186],"medication,":[113],"a":[115,130,136,148],"documented":[116],"disease-modifying":[117],"effect,":[118],"including":[119],"reduction":[120],"risk":[123],"patients":[125],"rhinitis.SCIT":[128],"has":[129],"longer":[131],"history":[132],"use":[134],"broader":[137],"body":[138],"evidence":[140],"supporting":[141],"whereas":[143],"is":[145],"characterised":[146],"by":[147],"more":[149],"favourable":[150],"profile":[152],"greater":[154],"convenience.Real-world":[156],"studies":[157],"indicate":[158],"that":[159,177],"adherence":[160],"one":[162],"important":[166],"determinants":[167],"long-term":[169],"effectiveness":[171],"modalities.Pharmacoeconomic":[174],"confirm":[176],"cost-effective":[183],"compared":[184],"alone,":[188],"although":[189],"their":[190],"cost":[191],"structures":[192],"differ":[193],"regard":[195],"medication":[197],"costs,":[198],"resource":[200],"utilisation,":[201],"costs":[204],"associated":[205],"work":[207],"productivity":[208],"loss":[209],"medical":[211],"visits.The":[212],"choice":[213],"modality":[216],"should":[217],"therefore":[218],"be":[219],"individualised":[220],"according":[221],"patient":[223],"characteristics,":[224],"disease":[225],"considerations,":[228],"organisational":[231],"factors.":[232]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-09-30T00:00:00"}