{"id":"https://openalex.org/W7214635258","doi":"https://doi.org/10.1007/s10103-026-05096-9","title":"Photobiomodulation modulates peripheral and central expression of inflammation-related genes following carrageenan-induced inflammation in rats","display_name":"Photobiomodulation modulates peripheral and central expression of inflammation-related genes following carrageenan-induced inflammation in rats","publication_year":2026,"publication_date":"2026-11-10","ids":{"openalex":"https://openalex.org/W7214635258","doi":"https://doi.org/10.1007/s10103-026-05096-9","pmid":"https://pubmed.ncbi.nlm.nih.gov/43004005"},"language":"en","primary_location":{"id":"doi:10.1007/s10103-026-05096-9","doi":"https://doi.org/10.1007/s10103-026-05096-9","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10103-026-05096-9","pdf_url":"https://link.springer.com/content/pdf/10.1007/s10103-026-05096-9.pdf","source":{"id":"https://openalex.org/S124030303","display_name":"Lasers in Medical Science","issn_l":"0268-8921","issn":["0268-8921","1435-604X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lasers in Medical Science","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s10103-026-05096-9.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051212177","display_name":"Carlos Alberto-Silva","orcid":"https://orcid.org/0000-0003-4519-8930","observed_orcids":["https://orcid.org/0000-0003-4519-8930"]},"institutions":[{"id":"https://openalex.org/I71715416","display_name":"Universidade Federal do ABC","ror":"https://ror.org/028kg9j04","country_code":"BR","type":"education","lineage":["https://openalex.org/I71715416"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Carlos Alberto-Silva","raw_affiliation_strings":["Natural and Humanities Sciences Center, Experimental Morphophysiology Laboratory, Universidade Federal do ABC, Santo Andr\u00e9, Brazil. carlos.asilva@ufabc.edu.br"],"raw_orcid":"https://orcid.org/0000-0003-4519-8930","affiliations":[{"raw_affiliation_string":"Natural and Humanities Sciences Center, Experimental Morphophysiology Laboratory, Universidade Federal do ABC, Santo Andr\u00e9, Brazil. carlos.asilva@ufabc.edu.br","institution_ids":["https://openalex.org/I71715416"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106576753","display_name":"Giulia Nicolle J\u00e1come Cartaxo","orcid":"https://orcid.org/0009-0004-5365-4953","observed_orcids":["https://orcid.org/0009-0004-5365-4953"]},"institutions":[{"id":"https://openalex.org/I122523194","display_name":"Universidade do Vale do Para\u00edba","ror":"https://ror.org/02gt27w49","country_code":"BR","type":"education","lineage":["https://openalex.org/I122523194"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Giulia Nicolle J\u00e1come Cartaxo","raw_affiliation_strings":["Instituto de Pesquisa e Desenvolvimento - IP&D, Universidade do Vale do Para\u00edba, S\u00e3o Jos\u00e9 dos Campos, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Pesquisa e Desenvolvimento - IP&D, Universidade do Vale do Para\u00edba, S\u00e3o Jos\u00e9 dos Campos, Brazil","institution_ids":["https://openalex.org/I122523194"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111138593","display_name":"Regiane dos Santos Feliciano","orcid":"https://orcid.org/0000-0002-0500-791X","observed_orcids":["https://orcid.org/0000-0002-0500-791X"]},"institutions":[{"id":"https://openalex.org/I3017888287","display_name":"Universidade Nove de Julho","ror":"https://ror.org/005mpbw70","country_code":"BR","type":"education","lineage":["https://openalex.org/I3017888287"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Regiane dos Santos Feliciano","raw_affiliation_strings":["Postgraduate Program in Biophotonics applied to Health Sciences, Universidade Nove de Julho, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Postgraduate Program in Biophotonics applied to Health Sciences, Universidade Nove de Julho, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I3017888287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021842845","display_name":"Bruna Calixto de Jesus","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3017888287","display_name":"Universidade Nove de Julho","ror":"https://ror.org/005mpbw70","country_code":"BR","type":"education","lineage":["https://openalex.org/I3017888287"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Bruna Calixto de Jesus","raw_affiliation_strings":["Postgraduate Program in Biophotonics applied to Health Sciences, Universidade Nove de Julho, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Postgraduate Program in Biophotonics applied to Health Sciences, Universidade Nove de Julho, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I3017888287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066178178","display_name":"J. F. Silva","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3017888287","display_name":"Universidade Nove de Julho","ror":"https://ror.org/005mpbw70","country_code":"BR","type":"education","lineage":["https://openalex.org/I3017888287"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Jos\u00e9 Ant\u00f4nio Silva-Junior","raw_affiliation_strings":["Postgraduate Program in Biophotonics applied to Health Sciences, Universidade Nove de Julho, S\u00e3o Paulo, Brazil. josejr@uni9.pro.br"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Postgraduate Program in Biophotonics applied to Health Sciences, Universidade Nove de Julho, S\u00e3o Paulo, Brazil. josejr@uni9.pro.br","institution_ids":["https://openalex.org/I3017888287"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5153340817","display_name":"Maricilia Silva Costa","orcid":"https://orcid.org/0000-0002-0141-7241","observed_orcids":["https://orcid.org/0000-0002-0141-7241"]},"institutions":[{"id":"https://openalex.org/I122523194","display_name":"Universidade do Vale do Para\u00edba","ror":"https://ror.org/02gt27w49","country_code":"BR","type":"education","lineage":["https://openalex.org/I122523194"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Maricilia Silva Costa","raw_affiliation_strings":["Instituto de Pesquisa e Desenvolvimento - IP&D, Universidade do Vale do Para\u00edba, S\u00e3o Jos\u00e9 dos Campos, Brazil. mscosta@univap.br"],"raw_orcid":"https://orcid.org/0000-0002-0141-7241","affiliations":[{"raw_affiliation_string":"Instituto de Pesquisa e Desenvolvimento - IP&D, Universidade do Vale do Para\u00edba, S\u00e3o Jos\u00e9 dos Campos, Brazil. mscosta@univap.br","institution_ids":["https://openalex.org/I122523194"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5051212177","https://openalex.org/A5066178178","https://openalex.org/A5153340817"],"corresponding_institution_ids":["https://openalex.org/I122523194","https://openalex.org/I3017888287","https://openalex.org/I71715416"],"apc_list":{"value":3590,"currency":"USD","value_usd":3590},"apc_paid":{"value":3590,"currency":"USD","value_usd":3590},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"41","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11566","display_name":"Laser Applications in Dentistry and Medicine","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11566","display_name":"Laser Applications in Dentistry and Medicine","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13044","display_name":"Biofield Effects and Biophysics","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/low-level-laser-therapy","display_name":"low-level laser therapy","score":0.9990000128746033},{"id":"https://openalex.org/keywords/carrageenan-induced-inflammation","display_name":"carrageenan-induced inflammation","score":0.8849999904632568},{"id":"https://openalex.org/keywords/peripheral-inflammation","display_name":"peripheral inflammation","score":0.8090000152587891},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.8450000286102295},{"id":"https://openalex.org/keywords/il-10","display_name":"IL-10","score":1.0},{"id":"https://openalex.org/keywords/prostacyclin-receptor","display_name":"prostacyclin receptor","score":0.8999999761581421},{"id":"https://openalex.org/keywords/kinin-b1-receptor","display_name":"kinin B1 receptor","score":0.8429999947547913},{"id":"https://openalex.org/keywords/kinin-b2-receptor","display_name":"kinin B2 receptor","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cytokine-gene-expression","display_name":"cytokine gene expression","score":0.7749999761581421},{"id":"https://openalex.org/keywords/nociception","display_name":"nociception","score":0.8830000162124634},{"id":"https://openalex.org/keywords/gene-expression-in-brain","display_name":"brain gene expression","score":0.5320000052452087},{"id":"https://openalex.org/keywords/660-nm-red-light","display_name":"660 nm red light","score":0.7429999709129333}],"concepts":[{"id":"https://openalex.org/C2776246183","wikidata":"https://www.wikidata.org/wiki/Q421924","display_name":"Kinin","level":4,"score":0.7908999919891357},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.7796000242233276},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.7605999708175659},{"id":"https://openalex.org/C46762472","wikidata":"https://www.wikidata.org/wiki/Q178648","display_name":"Peripheral","level":2,"score":0.6297000050544739},{"id":"https://openalex.org/C2993002077","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Receptor expression","level":3,"score":0.5785999894142151},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5375999808311462},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.5288000106811523},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5130000114440918},{"id":"https://openalex.org/C2781128415","wikidata":"https://www.wikidata.org/wiki/Q412050","display_name":"Prostacyclin","level":2,"score":0.40959998965263367},{"id":"https://openalex.org/C2781227287","wikidata":"https://www.wikidata.org/wiki/Q421991","display_name":"Carrageenan","level":2,"score":0.40790000557899475},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40610000491142273},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3492000102996826},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3325999975204468},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.33000001311302185},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.3271999955177307},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.29100000858306885},{"id":"https://openalex.org/C16613235","wikidata":"https://www.wikidata.org/wiki/Q285982","display_name":"Endogeny","level":2,"score":0.2797999978065491},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.25600001215934753}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D002351","descriptor_name":"Carrageenan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015850","descriptor_name":"Interleukin-6","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015850","descriptor_name":"Interleukin-6","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016753","descriptor_name":"Interleukin-10","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016753","descriptor_name":"Interleukin-10","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D028022","descriptor_name":"Low-Level Light Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D043782","descriptor_name":"Receptor, Bradykinin B2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D043783","descriptor_name":"Receptor, Bradykinin B1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D044006","descriptor_name":"Receptors, Epoprostenol","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D044006","descriptor_name":"Receptors, Epoprostenol","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/s10103-026-05096-9","doi":"https://doi.org/10.1007/s10103-026-05096-9","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10103-026-05096-9","pdf_url":"https://link.springer.com/content/pdf/10.1007/s10103-026-05096-9.pdf","source":{"id":"https://openalex.org/S124030303","display_name":"Lasers in Medical Science","issn_l":"0268-8921","issn":["0268-8921","1435-604X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lasers in Medical Science","raw_type":"journal-article"},{"id":"doi:10.21203/rs.3.rs-10910451/v1","doi":"https://doi.org/10.21203/rs.3.rs-10910451/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-10910451/v1","pdf_url":"https://www.researchsquare.com/article/rs-10910451/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},{"id":"pmid:43004005","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/43004005","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lasers in medical science","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1007/s10103-026-05096-9","doi":"https://doi.org/10.1007/s10103-026-05096-9","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10103-026-05096-9","pdf_url":"https://link.springer.com/content/pdf/10.1007/s10103-026-05096-9.pdf","source":{"id":"https://openalex.org/S124030303","display_name":"Lasers in Medical Science","issn_l":"0268-8921","issn":["0268-8921","1435-604X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lasers in Medical Science","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320997","display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","ror":"https://ror.org/02ddkpn78"},{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7214635258.pdf","grobid_xml":"https://content.openalex.org/works/W7214635258.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W1603278131","https://openalex.org/W2001196878","https://openalex.org/W2006518183","https://openalex.org/W2011871032","https://openalex.org/W2013164267","https://openalex.org/W2045488826","https://openalex.org/W2046983269","https://openalex.org/W2047142489","https://openalex.org/W2052720377","https://openalex.org/W2059885690","https://openalex.org/W2086179163","https://openalex.org/W2089771213","https://openalex.org/W2090510390","https://openalex.org/W2093843456","https://openalex.org/W2114202917","https://openalex.org/W2304401380","https://openalex.org/W2530439068","https://openalex.org/W2768877461","https://openalex.org/W2971390047","https://openalex.org/W4210526044","https://openalex.org/W4224300758","https://openalex.org/W4283030273","https://openalex.org/W4402246646","https://openalex.org/W4403016607","https://openalex.org/W4404866609","https://openalex.org/W4411198480","https://openalex.org/W4412519421","https://openalex.org/W4412543783"],"related_works":["https://openalex.org/W4411198480","https://openalex.org/W2761126525","https://openalex.org/W4311453611","https://openalex.org/W4362672521","https://openalex.org/W3189096922","https://openalex.org/W4392856882","https://openalex.org/W2530439068","https://openalex.org/W4415449512","https://openalex.org/W4410945913","https://openalex.org/W2810711642"],"abstract_inverted_index":{"Peripheral":[0],"inflammation":[1,44,221],"can":[2],"induce":[3],"molecular":[4],"changes":[5,226],"in":[6,32,37,45,98,129,185,190,227,233],"central":[7,40,242],"nervous":[8],"system":[9],"through":[10],"immune-brain":[11],"communication.":[12],"This":[13],"study":[14],"investigated":[15],"whether":[16],"photobiomodulation":[17],"(PBM)":[18],"modulates":[19],"the":[20,117,136,149,170,186,194],"temporal":[21],"mRNA":[22,80,107],"expression":[23,81,108,140,161,178,183,197,215,232,252,277],"of":[24,82,270],"pro-":[25],"and":[26,29,34,39,56,79,88,91,100,104,120,132,153,175,229,241,249,273],"anti-inflammatory":[27],"cytokines":[28],"receptors":[30,93],"involved":[31],"prostacyclin":[33,85],"kinin":[35,89,250,274],"signaling":[36],"peripheral":[38,220,240],"tissues":[41],"following":[42,207,278],"carrageenan-induced":[43],"rats.":[46],"Male":[47],"Wistar":[48],"rats":[49],"received":[50],"subplantar":[51,99,131],"carrageenan":[52,68,208],"injections":[53],"(1":[54],"mg/paw)":[55],"were":[57,71,121],"treated":[58],"or":[59,76],"not":[60],"with":[61],"PBM":[62,124,172,211,237],"(660":[63],"nm)":[64],"1":[65],"h":[66,115,147,202,206],"after":[67],"administration.":[69],"Animals":[70],"euthanized":[72],"at":[73,113,125,145,166,179,200,204,216,253],"1,":[74],"3,":[75],"6":[77,114,167,180,205,217],"h,":[78],"IL-6,":[83,247],"IL-10,":[84],"receptor":[86,106,139,160,177,251],"(IP),":[87],"B1":[90,138,174],"B2":[92,159,176],"was":[94,154,198,222],"quantified":[95],"by":[96,123,156,224,245,267],"qRT-PCR":[97],"brain":[101,133,234],"tissues.":[102,134],"IL-6":[103],"IP":[105],"showed":[109,141,162],"their":[110],"highest":[111,143],"levels":[112],"among":[116,148],"carrageenan-treated":[118],"groups":[119],"reduced":[122,155,173],"this":[126],"time":[127,150,255],"point":[128],"both":[130],"In":[135,169,193],"paw,":[137,187],"its":[142,163],"level":[144],"3":[146,201],"points":[151,256],"evaluated":[152],"PBM,":[157],"whereas":[158,210],"greatest":[164],"increase":[165],"h.":[168,181,218],"brain,":[171,195],"IL-10":[182,196,214,260],"increased":[184],"remaining":[188],"elevated":[189,213,259],"PBM-treated":[191],"animals.":[192],"higher":[199],"than":[203],"administration,":[209],"maintained":[212],"Carrageenan-induced":[219],"accompanied":[223],"time-dependent":[225],"inflammation-":[228],"nociception-related":[230],"gene":[231,276],"tissue.":[235],"Localized":[236],"modulated":[238],"these":[239],"transcriptional":[243],"responses":[244],"reducing":[246],"IP,":[248],"specific":[254],"while":[257],"maintaining":[258],"expression.":[261],"These":[262],"findings":[263],"extend":[264],"previous":[265],"observations":[266],"showing":[268],"modulation":[269],"cytokine,":[271],"prostacyclin,":[272],"signaling-related":[275],"localized":[279],"PBM.":[280]},"counts_by_year":[],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2026-09-29T00:00:00"}