{"id":"https://openalex.org/W7214618161","doi":"https://doi.org/10.64898/2026.09.26.26364042","title":"Pre-treatment EEG microstates and response to antipsychotic drugs in first episode psychosis","display_name":"Pre-treatment EEG microstates and response to antipsychotic drugs in first episode psychosis","publication_year":2026,"publication_date":"2026-09-28","ids":{"openalex":"https://openalex.org/W7214618161","doi":"https://doi.org/10.64898/2026.09.26.26364042","pmid":"https://pubmed.ncbi.nlm.nih.gov/42856625","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13648746"},"language":"en","primary_location":{"id":"doi:10.64898/2026.09.26.26364042","doi":"https://doi.org/10.64898/2026.09.26.26364042","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.26.26364042","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/28/2026.09.26.26364042.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/28/2026.09.26.26364042.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048257476","display_name":"Jos\u00e9 M. Rubio","orcid":"https://orcid.org/0000-0002-0056-4135","observed_orcids":["https://orcid.org/0000-0002-0056-4135"]},"institutions":[{"id":"https://openalex.org/I1327576362","display_name":"Feinstein Institute for Medical Research","ror":"https://ror.org/05dnene97","country_code":"US","type":"facility","lineage":["https://openalex.org/I1302444339","https://openalex.org/I1327576362"]},{"id":"https://openalex.org/I4210106353","display_name":"Donald & Barbara Zucker School of Medicine at Hofstra/Northwell","ror":"https://ror.org/01ff5td15","country_code":"US","type":"education","lineage":["https://openalex.org/I1302444339","https://openalex.org/I139290212","https://openalex.org/I4210106353"]},{"id":"https://openalex.org/I4210166545","display_name":"Zucker Hillside Hospital","ror":"https://ror.org/05vh9vp33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1302444339","https://openalex.org/I4210166545"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jose M Rubio","raw_affiliation_strings":["Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Hempstead, NY, USA","Feinstein Institutes for Medical Research, Institute of Behavioral Science, Manhasset, NY, USA","The Zucker Hillside Hospital, Glen Oaks, NY, USA"],"raw_orcid":"https://orcid.org/0000-0002-0056-4135","affiliations":[{"raw_affiliation_string":"Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Hempstead, NY, USA","institution_ids":["https://openalex.org/I4210106353"]},{"raw_affiliation_string":"Feinstein Institutes for Medical Research, Institute of Behavioral Science, Manhasset, NY, USA","institution_ids":["https://openalex.org/I1327576362"]},{"raw_affiliation_string":"The Zucker Hillside Hospital, Glen Oaks, NY, USA","institution_ids":["https://openalex.org/I4210166545"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5153345618","display_name":"Michael Murphy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801148111","display_name":"McLean Hospital","ror":"https://ror.org/01kta7d96","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801148111"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Murphy","raw_affiliation_strings":["Harvard Medical School, Boston, MA, USA","McLean Hospital, Belmont, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"McLean Hospital, Belmont, MA, USA","institution_ids":["https://openalex.org/I2801148111"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071951352","display_name":"Wadim Vodovozov","orcid":"https://orcid.org/0000-0002-8932-3935","observed_orcids":["https://orcid.org/0000-0002-8932-3935"]},"institutions":[{"id":"https://openalex.org/I1327576362","display_name":"Feinstein Institute for Medical Research","ror":"https://ror.org/05dnene97","country_code":"US","type":"facility","lineage":["https://openalex.org/I1302444339","https://openalex.org/I1327576362"]},{"id":"https://openalex.org/I4210106353","display_name":"Donald & Barbara Zucker School of Medicine at Hofstra/Northwell","ror":"https://ror.org/01ff5td15","country_code":"US","type":"education","lineage":["https://openalex.org/I1302444339","https://openalex.org/I139290212","https://openalex.org/I4210106353"]},{"id":"https://openalex.org/I4210166545","display_name":"Zucker Hillside Hospital","ror":"https://ror.org/05vh9vp33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1302444339","https://openalex.org/I4210166545"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wadim Vodovozov","raw_affiliation_strings":["Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Hempstead, NY, USA","Feinstein Institutes for Medical Research, Institute of Behavioral Science, Manhasset, NY, USA","The Zucker Hillside Hospital, Glen Oaks, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Hempstead, NY, USA","institution_ids":["https://openalex.org/I4210106353"]},{"raw_affiliation_string":"Feinstein Institutes for Medical Research, Institute of Behavioral Science, Manhasset, NY, USA","institution_ids":["https://openalex.org/I1327576362"]},{"raw_affiliation_string":"The Zucker Hillside Hospital, Glen Oaks, NY, USA","institution_ids":["https://openalex.org/I4210166545"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102967348","display_name":"Ricardo Carrion","orcid":"https://orcid.org/0000-0001-7046-7683","observed_orcids":["https://orcid.org/0000-0001-7046-7683"]},"institutions":[{"id":"https://openalex.org/I1327576362","display_name":"Feinstein Institute for Medical Research","ror":"https://ror.org/05dnene97","country_code":"US","type":"facility","lineage":["https://openalex.org/I1302444339","https://openalex.org/I1327576362"]},{"id":"https://openalex.org/I4210106353","display_name":"Donald & Barbara Zucker School of Medicine at Hofstra/Northwell","ror":"https://ror.org/01ff5td15","country_code":"US","type":"education","lineage":["https://openalex.org/I1302444339","https://openalex.org/I139290212","https://openalex.org/I4210106353"]},{"id":"https://openalex.org/I4210166545","display_name":"Zucker Hillside Hospital","ror":"https://ror.org/05vh9vp33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1302444339","https://openalex.org/I4210166545"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ricardo Carrion","raw_affiliation_strings":["Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Hempstead, NY, USA","Feinstein Institutes for Medical Research, Institute of Behavioral Science, Manhasset, NY, USA","The Zucker Hillside Hospital, Glen Oaks, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Hempstead, NY, USA","institution_ids":["https://openalex.org/I4210106353"]},{"raw_affiliation_string":"Feinstein Institutes for Medical Research, Institute of Behavioral Science, Manhasset, NY, USA","institution_ids":["https://openalex.org/I1327576362"]},{"raw_affiliation_string":"The Zucker Hillside Hospital, Glen Oaks, NY, USA","institution_ids":["https://openalex.org/I4210166545"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009515693","display_name":"Todd Lencz","orcid":"https://orcid.org/0000-0001-8586-338X","observed_orcids":["https://orcid.org/0000-0001-8586-338X"]},"institutions":[{"id":"https://openalex.org/I1327576362","display_name":"Feinstein Institute for Medical Research","ror":"https://ror.org/05dnene97","country_code":"US","type":"facility","lineage":["https://openalex.org/I1302444339","https://openalex.org/I1327576362"]},{"id":"https://openalex.org/I4210106353","display_name":"Donald & Barbara Zucker School of Medicine at Hofstra/Northwell","ror":"https://ror.org/01ff5td15","country_code":"US","type":"education","lineage":["https://openalex.org/I1302444339","https://openalex.org/I139290212","https://openalex.org/I4210106353"]},{"id":"https://openalex.org/I4210166545","display_name":"Zucker Hillside Hospital","ror":"https://ror.org/05vh9vp33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1302444339","https://openalex.org/I4210166545"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Todd Lencz","raw_affiliation_strings":["Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Hempstead, NY, USA","Feinstein Institutes for Medical Research, Institute of Behavioral Science, Manhasset, NY, USA","The Zucker Hillside Hospital, Glen Oaks, NY, USA"],"raw_orcid":"https://orcid.org/0000-0001-8586-338X","affiliations":[{"raw_affiliation_string":"Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Hempstead, NY, USA","institution_ids":["https://openalex.org/I4210106353"]},{"raw_affiliation_string":"Feinstein Institutes for Medical Research, Institute of Behavioral Science, Manhasset, NY, USA","institution_ids":["https://openalex.org/I1327576362"]},{"raw_affiliation_string":"The Zucker Hillside Hospital, Glen Oaks, NY, USA","institution_ids":["https://openalex.org/I4210166545"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082430912","display_name":"M\u00e1t\u00e9 Baradits","orcid":"https://orcid.org/0000-0003-1131-4550","observed_orcids":["https://orcid.org/0000-0003-1131-4550"]},"institutions":[{"id":"https://openalex.org/I1327576362","display_name":"Feinstein Institute for Medical Research","ror":"https://ror.org/05dnene97","country_code":"US","type":"facility","lineage":["https://openalex.org/I1302444339","https://openalex.org/I1327576362"]},{"id":"https://openalex.org/I4210106353","display_name":"Donald & Barbara Zucker School of Medicine at Hofstra/Northwell","ror":"https://ror.org/01ff5td15","country_code":"US","type":"education","lineage":["https://openalex.org/I1302444339","https://openalex.org/I139290212","https://openalex.org/I4210106353"]},{"id":"https://openalex.org/I4210166545","display_name":"Zucker Hillside Hospital","ror":"https://ror.org/05vh9vp33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1302444339","https://openalex.org/I4210166545"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mate Baradits","raw_affiliation_strings":["Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Hempstead, NY, USA","Feinstein Institutes for Medical Research, Institute of Behavioral Science, Manhasset, NY, USA","The Zucker Hillside Hospital, Glen Oaks, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Hempstead, NY, USA","institution_ids":["https://openalex.org/I4210106353"]},{"raw_affiliation_string":"Feinstein Institutes for Medical Research, Institute of Behavioral Science, Manhasset, NY, USA","institution_ids":["https://openalex.org/I1327576362"]},{"raw_affiliation_string":"The Zucker Hillside Hospital, Glen Oaks, NY, USA","institution_ids":["https://openalex.org/I4210166545"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5153302746","display_name":"Dost Ongur","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801148111","display_name":"McLean Hospital","ror":"https://ror.org/01kta7d96","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801148111"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dost Ongur","raw_affiliation_strings":["Harvard Medical School, Boston, MA, USA","McLean Hospital, Belmont, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"McLean Hospital, Belmont, MA, USA","institution_ids":["https://openalex.org/I2801148111"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061506125","display_name":"Mehrdad Sadri","orcid":"https://orcid.org/0009-0001-4920-4827","observed_orcids":["https://orcid.org/0009-0001-4920-4827"]},"institutions":[{"id":"https://openalex.org/I1327576362","display_name":"Feinstein Institute for Medical Research","ror":"https://ror.org/05dnene97","country_code":"US","type":"facility","lineage":["https://openalex.org/I1302444339","https://openalex.org/I1327576362"]},{"id":"https://openalex.org/I4210106353","display_name":"Donald & Barbara Zucker School of Medicine at Hofstra/Northwell","ror":"https://ror.org/01ff5td15","country_code":"US","type":"education","lineage":["https://openalex.org/I1302444339","https://openalex.org/I139290212","https://openalex.org/I4210106353"]},{"id":"https://openalex.org/I4210166545","display_name":"Zucker Hillside Hospital","ror":"https://ror.org/05vh9vp33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1302444339","https://openalex.org/I4210166545"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mehrdad Sadri","raw_affiliation_strings":["Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Hempstead, NY, USA","Feinstein Institutes for Medical Research, Institute of Behavioral Science, Manhasset, NY, USA","The Zucker Hillside Hospital, Glen Oaks, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Hempstead, NY, USA","institution_ids":["https://openalex.org/I4210106353"]},{"raw_affiliation_string":"Feinstein Institutes for Medical Research, Institute of Behavioral Science, Manhasset, NY, USA","institution_ids":["https://openalex.org/I1327576362"]},{"raw_affiliation_string":"The Zucker Hillside Hospital, Glen Oaks, NY, USA","institution_ids":["https://openalex.org/I4210166545"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5134584349","display_name":"John M. Kane","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1327576362","display_name":"Feinstein Institute for Medical Research","ror":"https://ror.org/05dnene97","country_code":"US","type":"facility","lineage":["https://openalex.org/I1302444339","https://openalex.org/I1327576362"]},{"id":"https://openalex.org/I4210106353","display_name":"Donald & Barbara Zucker School of Medicine at Hofstra/Northwell","ror":"https://ror.org/01ff5td15","country_code":"US","type":"education","lineage":["https://openalex.org/I1302444339","https://openalex.org/I139290212","https://openalex.org/I4210106353"]},{"id":"https://openalex.org/I4210166545","display_name":"Zucker Hillside Hospital","ror":"https://ror.org/05vh9vp33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1302444339","https://openalex.org/I4210166545"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John M Kane","raw_affiliation_strings":["Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Hempstead, NY, USA","Feinstein Institutes for Medical Research, Institute of Behavioral Science, Manhasset, NY, USA","The Zucker Hillside Hospital, Glen Oaks, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Hempstead, NY, USA","institution_ids":["https://openalex.org/I4210106353"]},{"raw_affiliation_string":"Feinstein Institutes for Medical Research, Institute of Behavioral Science, Manhasset, NY, USA","institution_ids":["https://openalex.org/I1327576362"]},{"raw_affiliation_string":"The Zucker Hillside Hospital, Glen Oaks, NY, USA","institution_ids":["https://openalex.org/I4210166545"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5134616347","display_name":"Anil K. Malhotra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1327576362","display_name":"Feinstein Institute for Medical Research","ror":"https://ror.org/05dnene97","country_code":"US","type":"facility","lineage":["https://openalex.org/I1302444339","https://openalex.org/I1327576362"]},{"id":"https://openalex.org/I4210106353","display_name":"Donald & Barbara Zucker School of Medicine at Hofstra/Northwell","ror":"https://ror.org/01ff5td15","country_code":"US","type":"education","lineage":["https://openalex.org/I1302444339","https://openalex.org/I139290212","https://openalex.org/I4210106353"]},{"id":"https://openalex.org/I4210166545","display_name":"Zucker Hillside Hospital","ror":"https://ror.org/05vh9vp33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1302444339","https://openalex.org/I4210166545"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anil K Malhotra","raw_affiliation_strings":["Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Hempstead, NY, USA","Feinstein Institutes for Medical Research, Institute of Behavioral Science, Manhasset, NY, USA","The Zucker Hillside Hospital, Glen Oaks, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Hempstead, NY, USA","institution_ids":["https://openalex.org/I4210106353"]},{"raw_affiliation_string":"Feinstein Institutes for Medical Research, Institute of Behavioral Science, Manhasset, NY, USA","institution_ids":["https://openalex.org/I1327576362"]},{"raw_affiliation_string":"The Zucker Hillside Hospital, Glen Oaks, NY, USA","institution_ids":["https://openalex.org/I4210166545"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5048257476"],"corresponding_institution_ids":["https://openalex.org/I1327576362","https://openalex.org/I4210106353","https://openalex.org/I4210166545"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/first-episode-psychosis","display_name":"first-episode psychosis","score":0.8510000109672546},{"id":"https://openalex.org/keywords/eeg-microstates","display_name":"EEG microstates","score":0.8980000019073486},{"id":"https://openalex.org/keywords/antipsychotic-treatment-response","display_name":"antipsychotic treatment response","score":0.9359999895095825},{"id":"https://openalex.org/keywords/predictive-biomarkers","display_name":"predictive biomarkers","score":0.8970000147819519},{"id":"https://openalex.org/keywords/resting-state-eeg","display_name":"resting-state EEG","score":0.7919999957084656},{"id":"https://openalex.org/keywords/treatment-resistant-psychosis","display_name":"treatment-resistant psychosis","score":0.5440000295639038},{"id":"https://openalex.org/keywords/k-means-clustering","display_name":"K-means clustering","score":0.6399999856948853}],"concepts":[{"id":"https://openalex.org/C45424060","wikidata":"https://www.wikidata.org/wiki/Q244381","display_name":"Ministate","level":3,"score":0.8755000233650208},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.635200023651123},{"id":"https://openalex.org/C44725695","wikidata":"https://www.wikidata.org/wiki/Q288156","display_name":"Normative","level":2,"score":0.5322999954223633},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.46720001101493835},{"id":"https://openalex.org/C2779727114","wikidata":"https://www.wikidata.org/wiki/Q170082","display_name":"Psychosis","level":2,"score":0.4668999910354614},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.38429999351501465},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.3822000026702881},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.38109999895095825},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.37040001153945923},{"id":"https://openalex.org/C2780494398","wikidata":"https://www.wikidata.org/wiki/Q208144","display_name":"Antipsychotic","level":3,"score":0.36239999532699585},{"id":"https://openalex.org/C3019878999","wikidata":"https://www.wikidata.org/wiki/Q208144","display_name":"Antipsychotic drug","level":4,"score":0.33469998836517334},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.3125},{"id":"https://openalex.org/C73269764","wikidata":"https://www.wikidata.org/wiki/Q954529","display_name":"Poisson regression","level":3,"score":0.28610000014305115},{"id":"https://openalex.org/C2778375690","wikidata":"https://www.wikidata.org/wiki/Q7814214","display_name":"Tolerability","level":3,"score":0.2685999870300293},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.2565999925136566},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.2556999921798706},{"id":"https://openalex.org/C2779226451","wikidata":"https://www.wikidata.org/wiki/Q903809","display_name":"Functional magnetic resonance imaging","level":2,"score":0.25290000438690186},{"id":"https://openalex.org/C191795146","wikidata":"https://www.wikidata.org/wiki/Q3878446","display_name":"Norm (philosophy)","level":2,"score":0.2526000142097473}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.64898/2026.09.26.26364042","doi":"https://doi.org/10.64898/2026.09.26.26364042","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.26.26364042","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/28/2026.09.26.26364042.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},{"id":"pmid:42856625","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42856625","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"medRxiv : the preprint server for health sciences","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13648746","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13648746/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"medRxiv","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.64898/2026.09.26.26364042","doi":"https://doi.org/10.64898/2026.09.26.26364042","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.26.26364042","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/28/2026.09.26.26364042.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7214618161.pdf","grobid_xml":"https://content.openalex.org/works/W7214618161.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4362734294","https://openalex.org/W4407082048","https://openalex.org/W4317749959","https://openalex.org/W3107641605","https://openalex.org/W7164091991","https://openalex.org/W4389509965","https://openalex.org/W4401920448","https://openalex.org/W4417152319","https://openalex.org/W4413015121","https://openalex.org/W7161556873"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"and":[2,43,129],"Hypothesis":[3],"First-line":[4],"antipsychotics":[5],"are":[6],"ineffective":[7],"in":[8,34,56,107,150,186,215,229,250],"\u223c40%":[9],"of":[10,62,67,82,114,119,163,173,247],"people":[11],"with":[12,194,244],"first":[13,78],"episode":[14],"psychosis":[15],"(FEP).":[16],"Electroencephalogram":[17],"(EEG)-based":[18],"predictive":[19],"biomarkers":[20],"could":[21],"be":[22],"a":[23,90,116,222],"scalable":[24],"solution":[25,128],"to":[26,103,131,167,203],"reduce":[27],"trial-and-error.":[28],"Study":[29,152],"Design":[30],"We":[31],"acquired":[32],"EEG":[33,69,208,234],"56":[35],"minimally":[36],"treated":[37],"FEP":[38,95,216,230],"individuals":[39],"before":[40],"treatment":[41,105,179,248],"initiation,":[42],"34":[44],"matched":[45],"healthy":[46,206],"controls":[47],"(HC).":[48],"Treatment":[49],"response":[50,106,149,180,228,249],"was":[51,101,122],"defined":[52],"as":[53,89],">50%":[54],"improvement":[55],"BPRS":[57],"scores":[58,137],"by":[59],"12":[60],"weeks":[61],"treatment.":[63],"Modified":[64],"k-means":[65],"clustering":[66],"resting-state":[68],"yielded":[70],"six":[71],"microstates":[72,155],"including":[73],"canonical":[74],"topographies":[75],"(A-D).":[76],"The":[77],"principal":[79],"component":[80],"(PC1)":[81],"microstate":[83,127,164,235],"properties":[84],"derived":[85,138,217],"from":[86,139,198,221,238],"HCs":[87,120],"served":[88],"normative":[91,142,224],"reference":[92],"onto":[93],"which":[94],"patients":[96],"were":[97,144],"projected.":[98],"Baseline":[99,175],"PC1":[100,136,170,176,197,214,219],"used":[102,146],"predict":[104],"adjusted":[108],"regression":[109],"analyses.":[110],"To":[111],"test":[112],"stability":[113],"results,":[115],"second":[117,205,223],"dataset":[118,143,209,225],"(n=92)":[121,210],"fitted":[123],"using":[124,218],"the":[125,204,239],"same":[126],"compared":[130,166],"our":[132,199],"native":[133],"HC":[134,200],"dataset.":[135],"this":[140],"independent":[141],"also":[145,226],"for":[147],"predicting":[148],"FEP.":[151,251],"Results":[153],"Individual":[154],"replicated":[156],"established":[157],"patient-control":[158],"differences":[159],"(e.g.,":[160],"higher":[161],"presence":[162],"C":[165],"D,":[168],"p<0.001).":[169],"explained":[171],"34.8%":[172],"variance.":[174],"predicted":[177,227],"subsequent":[178],"(adjusted":[181],"OR=0.63,":[182],"p<0.001),":[183],"yielding":[184],"AUC=72.3%":[185],"leave-one-out":[187],"cross-validation":[188],"(p":[189],"perm":[190],"<0.001)":[191],"when":[192],"combined":[193],"clinical":[195],"information.":[196],"transported":[201],"well":[202],"control":[207],"(r=0.9,p<0.001;":[211],"r=0.89,p<0.001":[212],").":[213],"weights":[220],"(OR=0.70,":[231],"p=0.03).":[232],"Conclusions":[233],"architecture":[236],"differing":[237],"expected":[240],"norm":[241],"is":[242],"associated":[243],"lower":[245],"odds":[246]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-09-29T00:00:00"}