{"id":"https://openalex.org/W7214596302","doi":"https://doi.org/10.3390/ijms27198631","title":"Effects of Crude Polysaccharides from Lentinula edodes Obtained by Ultrasound-Assisted Water Extraction on Metabolic and Hepatic Parameters in Obese Rats","display_name":"Effects of Crude Polysaccharides from Lentinula edodes Obtained by Ultrasound-Assisted Water Extraction on Metabolic and Hepatic Parameters in Obese Rats","publication_year":2026,"publication_date":"2026-09-26","ids":{"openalex":"https://openalex.org/W7214596302","doi":"https://doi.org/10.3390/ijms27198631","pmid":"https://pubmed.ncbi.nlm.nih.gov/42883879","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13665417"},"language":"en","primary_location":{"id":"doi:10.3390/ijms27198631","doi":"https://doi.org/10.3390/ijms27198631","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms27198631","pdf_url":null,"source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/ijms27198631","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5118885519","display_name":"Nannapat Phosarith","orcid":"https://orcid.org/0009-0000-5825-7851","observed_orcids":["https://orcid.org/0009-0000-5825-7851"]},"institutions":[{"id":"https://openalex.org/I48076826","display_name":"Chiang Mai University","ror":"https://ror.org/05m2fqn25","country_code":"TH","type":"education","lineage":["https://openalex.org/I48076826"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Nannapat Phosarith","raw_affiliation_strings":["Division of Food Science and Technology, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand"],"raw_orcid":"https://orcid.org/0009-0000-5825-7851","affiliations":[{"raw_affiliation_string":"Division of Food Science and Technology, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand","institution_ids":["https://openalex.org/I48076826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000741414","display_name":"Thanyaporn Siriwoharn","orcid":"https://orcid.org/0000-0001-9060-3662","observed_orcids":["https://orcid.org/0000-0001-9060-3662"]},"institutions":[{"id":"https://openalex.org/I48076826","display_name":"Chiang Mai University","ror":"https://ror.org/05m2fqn25","country_code":"TH","type":"education","lineage":["https://openalex.org/I48076826"]}],"countries":["TH"],"is_corresponding":true,"raw_author_name":"Thanyaporn Siriwoharn","raw_affiliation_strings":["Division of Food Science and Technology, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand"],"raw_orcid":"https://orcid.org/0000-0001-9060-3662","affiliations":[{"raw_affiliation_string":"Division of Food Science and Technology, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand","institution_ids":["https://openalex.org/I48076826"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091809550","display_name":"Wachira Jirarattanarangsri","orcid":"https://orcid.org/0000-0001-6059-024X","observed_orcids":["https://orcid.org/0000-0001-6059-024X"]},"institutions":[{"id":"https://openalex.org/I48076826","display_name":"Chiang Mai University","ror":"https://ror.org/05m2fqn25","country_code":"TH","type":"education","lineage":["https://openalex.org/I48076826"]}],"countries":["TH"],"is_corresponding":true,"raw_author_name":"Wachira Jirarattanarangsri","raw_affiliation_strings":["Division of Food Science and Technology, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand"],"raw_orcid":"https://orcid.org/0000-0001-6059-024X","affiliations":[{"raw_affiliation_string":"Division of Food Science and Technology, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand","institution_ids":["https://openalex.org/I48076826"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5000741414","https://openalex.org/A5091809550"],"corresponding_institution_ids":["https://openalex.org/I48076826"],"apc_list":{"value":2900,"currency":"CHF","value_usd":3499},"apc_paid":{"value":2900,"currency":"CHF","value_usd":3499},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.65980813,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"27","issue":"19","first_page":"8631","last_page":"8631"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11085","display_name":"Fungal Biology and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11085","display_name":"Fungal Biology and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12964","display_name":"Diet, Metabolism, and Disease","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lentinula-edodes","display_name":"shiitake mushroom","score":0.9929999709129333},{"id":"https://openalex.org/keywords/shiitake-mushroom-polysaccharides","display_name":"shiitake mushroom polysaccharides","score":0.9380000233650208},{"id":"https://openalex.org/keywords/high-fat-diet","display_name":"high-fat diet","score":0.9829999804496765},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.9800000190734863},{"id":"https://openalex.org/keywords/hepatic-steatosis","display_name":"hepatic steatosis","score":0.8790000081062317},{"id":"https://openalex.org/keywords/liver-enzymes","display_name":"liver enzymes","score":0.5640000104904175},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.5040000081062317},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.9670000076293945},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.6710000038146973},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.8989999890327454},{"id":"https://openalex.org/keywords/functional-food-ingredients","display_name":"functional food ingredients","score":0.8489999771118164},{"id":"https://openalex.org/keywords/metabolic-disorders","display_name":"metabolic disorders","score":0.3610000014305115}],"concepts":[{"id":"https://openalex.org/C2776236347","wikidata":"https://www.wikidata.org/wiki/Q1303903","display_name":"Lentinula","level":3,"score":0.8662999868392944},{"id":"https://openalex.org/C100817775","wikidata":"https://www.wikidata.org/wiki/Q134219","display_name":"Polysaccharide","level":2,"score":0.7710999846458435},{"id":"https://openalex.org/C2776175330","wikidata":"https://www.wikidata.org/wiki/Q1365091","display_name":"Steatosis","level":2,"score":0.7139999866485596},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6053000092506409},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.503000020980835},{"id":"https://openalex.org/C2780589914","wikidata":"https://www.wikidata.org/wiki/Q10675206","display_name":"Ingredient","level":2,"score":0.39559999108314514},{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.3889000117778778},{"id":"https://openalex.org/C2775980262","wikidata":"https://www.wikidata.org/wiki/Q218870","display_name":"Prebiotic","level":2,"score":0.36899998784065247},{"id":"https://openalex.org/C2778395939","wikidata":"https://www.wikidata.org/wiki/Q2160967","display_name":"Water extraction","level":3,"score":0.36149999499320984},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3596999943256378},{"id":"https://openalex.org/C4725764","wikidata":"https://www.wikidata.org/wiki/Q844704","display_name":"Extraction (chemistry)","level":2,"score":0.33709999918937683},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.33169999718666077},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3312999904155731},{"id":"https://openalex.org/C2777507495","wikidata":"https://www.wikidata.org/wiki/Q185317","display_name":"Cecum","level":2,"score":0.3089999854564667},{"id":"https://openalex.org/C192989942","wikidata":"https://www.wikidata.org/wiki/Q68685","display_name":"Metabolic pathway","level":3,"score":0.2962999939918518},{"id":"https://openalex.org/C17857428","wikidata":"https://www.wikidata.org/wiki/Q533025","display_name":"Nutraceutical","level":2,"score":0.2874000072479248},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.2863999903202057},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.28209999203681946},{"id":"https://openalex.org/C147583825","wikidata":"https://www.wikidata.org/wiki/Q620876","display_name":"Body weight","level":2,"score":0.26089999079704285}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007333","descriptor_name":"Insulin Resistance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011134","descriptor_name":"Polysaccharides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011134","descriptor_name":"Polysaccharides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020942","descriptor_name":"Shiitake Mushrooms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059305","descriptor_name":"Diet, High-Fat","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3390/ijms27198631","doi":"https://doi.org/10.3390/ijms27198631","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms27198631","pdf_url":null,"source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13665417","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13665417/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13665417/pdf/ijms-27-08631.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Mol Sci","raw_type":"Text"},{"id":"pmid:42883879","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42883879","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of molecular sciences","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3390/ijms27198631","doi":"https://doi.org/10.3390/ijms27198631","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms27198631","pdf_url":null,"source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8999999761581421,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321529","display_name":"Chiang Mai University","ror":"https://ror.org/05m2fqn25"},{"id":"https://openalex.org/F4320335053","display_name":"Faculty of Agro-Industry, Chiang Mai University","ror":"https://ror.org/05m2fqn25"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7214596302.pdf","grobid_xml":"https://content.openalex.org/works/W7214596302.grobid-xml"},"referenced_works_count":68,"referenced_works":["https://openalex.org/W1852340166","https://openalex.org/W1919048856","https://openalex.org/W1967732008","https://openalex.org/W2021688906","https://openalex.org/W2067740038","https://openalex.org/W2124552642","https://openalex.org/W2143104968","https://openalex.org/W2158594746","https://openalex.org/W2232762837","https://openalex.org/W2290110623","https://openalex.org/W2460367349","https://openalex.org/W2914022070","https://openalex.org/W2921779752","https://openalex.org/W2933653353","https://openalex.org/W2945174380","https://openalex.org/W2971508067","https://openalex.org/W2993862932","https://openalex.org/W2995244387","https://openalex.org/W3002100009","https://openalex.org/W3006097165","https://openalex.org/W3014052247","https://openalex.org/W3018456801","https://openalex.org/W3021320818","https://openalex.org/W3119716895","https://openalex.org/W3164101818","https://openalex.org/W3191234518","https://openalex.org/W3196808915","https://openalex.org/W3216366140","https://openalex.org/W4200215705","https://openalex.org/W4205828228","https://openalex.org/W4206295574","https://openalex.org/W4213012232","https://openalex.org/W4213219431","https://openalex.org/W4213249136","https://openalex.org/W4229046671","https://openalex.org/W4233971050","https://openalex.org/W4280571671","https://openalex.org/W4281648354","https://openalex.org/W4288885871","https://openalex.org/W4290490370","https://openalex.org/W4290999457","https://openalex.org/W4296513766","https://openalex.org/W4311942892","https://openalex.org/W4319657087","https://openalex.org/W4319985762","https://openalex.org/W4321611099","https://openalex.org/W4322743589","https://openalex.org/W4322774851","https://openalex.org/W4361214502","https://openalex.org/W4361295243","https://openalex.org/W4365146108","https://openalex.org/W4366418525","https://openalex.org/W4375955850","https://openalex.org/W4376121720","https://openalex.org/W4385895544","https://openalex.org/W4386368735","https://openalex.org/W4387081360","https://openalex.org/W4391410909","https://openalex.org/W4399857158","https://openalex.org/W4400722579","https://openalex.org/W4401456643","https://openalex.org/W4407852621","https://openalex.org/W4409557445","https://openalex.org/W4411227554","https://openalex.org/W4411436282","https://openalex.org/W4412155027","https://openalex.org/W4413396916","https://openalex.org/W4415585113"],"related_works":["https://openalex.org/W3157285813","https://openalex.org/W4414675425","https://openalex.org/W1939569768","https://openalex.org/W4317911424","https://openalex.org/W2359148450","https://openalex.org/W3202003025","https://openalex.org/W2288996818","https://openalex.org/W2054638674","https://openalex.org/W2470124797","https://openalex.org/W4388573266"],"abstract_inverted_index":{"A":[0],"high-fat":[1,48,78],"diet":[2,79],"is":[3],"associated":[4],"with":[5,103,123,165,201],"metabolic":[6,25,44,68,218],"disorder,":[7],"including":[8],"obesity,":[9],"insulin":[10],"resistance,":[11],"dyslipidemia,":[12],"and":[13,26,72,142,149,158,197],"hypertension.":[14],"Polysaccharides":[15],"derived":[16,35],"from":[17,36,169],"mushrooms":[18],"have":[19],"attracted":[20],"interest":[21],"for":[22,119],"their":[23],"potential":[24,207],"anti-inflammatory":[27],"effects.":[28],"Nevertheless,":[29],"the":[30,37,58,124,130,166,174,182,206],"impact":[31],"of":[32,60,208],"crude":[33],"polysaccharides":[34],"Lentinula":[38],"edodes":[39],"(Berk.)":[40],"Pegler":[41],"(PSC)":[42],"on":[43,67],"conditions":[45],"linked":[46],"to":[47,56,96,177,216],"diets":[49],"remains":[50],"insufficiently":[51],"studied.":[52],"This":[53,203],"study":[54,204],"aimed":[55],"evaluate":[57],"bioactivity":[59],"PSC":[61,106,108,162,183,191,209],"obtained":[62],"using":[63],"ultrasound-water":[64],"extraction":[65],"(UW)":[66],"parameters,":[69],"hepatic":[70,156],"function,":[71],"inflammation":[73],"in":[74,173,181],"rats":[75,83],"fed":[76],"a":[77,190,212],"(HFD).":[80],"Male":[81],"Wistar":[82],"(5":[84],"weeks":[85],"old,":[86],"180\u2013200":[87],"g;":[88],"n":[89],"=":[90],"6":[91],"per":[92],"group)":[93],"were":[94,145],"assigned":[95],"normal-diet":[97],"(ND)":[98],"or":[99,104],"high-fat-diet":[100],"(HFD)":[101],"groups,":[102],"without":[105],"administration.":[107,185],"was":[109],"administered":[110],"by":[111],"oral":[112],"gavage":[113],"at":[114,127],"400":[115],"mg/kg":[116],"body":[117],"weight/day":[118],"4":[120],"weeks.":[121],"Compared":[122],"HFD":[125,175],"group":[126,132,176],"week":[128],"20,":[129],"HFD+PSC":[131],"showed":[133,154],"30.44%":[134],"lower":[135],"body-weight":[136],"gain,":[137],"while":[138],"LDL-C,":[139],"AST,":[140],"ALT,":[141],"IL-6":[143],"levels":[144],"42.31%,":[146],"35.77%,":[147],"55.15%,":[148],"41.78%":[150],"lower.":[151],"Histopathological":[152],"examination":[153],"reduced":[155],"steatosis":[157],"inflammatory":[159,198],"alterations":[160],"following":[161],"extract":[163,184,192,210],"administration,":[164],"NAS":[167],"decreasing":[168],"5.60":[170],"\u00b1":[171,179],"0.51":[172],"2.00":[178],"0.32":[180],"The":[186],"findings":[187],"indicate":[188],"that":[189],"decreased":[193],"various":[194],"metabolic,":[195],"hepatic,":[196],"changes":[199],"correlated":[200],"HFD.":[202],"supports":[205],"as":[211],"mushrooms-derived":[213],"functional":[214],"ingredient":[215],"improve":[217],"function.":[219]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-09-29T00:00:00"}