{"id":"https://openalex.org/W7214518631","doi":"https://doi.org/10.64898/2026.09.24.26363942","title":"Adult Patient Perspectives on Psychiatric Polygenic Risk Scores","display_name":"Adult Patient Perspectives on Psychiatric Polygenic Risk Scores","publication_year":2026,"publication_date":"2026-09-27","ids":{"openalex":"https://openalex.org/W7214518631","doi":"https://doi.org/10.64898/2026.09.24.26363942","pmid":"https://pubmed.ncbi.nlm.nih.gov/42818454","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13622423"},"language":"en","primary_location":{"id":"doi:10.64898/2026.09.24.26363942","doi":"https://doi.org/10.64898/2026.09.24.26363942","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.24.26363942","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/27/2026.09.24.26363942.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/27/2026.09.24.26363942.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047319335","display_name":"Craig Waldence McFarland","orcid":"https://orcid.org/0009-0004-9063-7984","observed_orcids":["https://orcid.org/0009-0004-9063-7984"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Craig W. McFarland","raw_affiliation_strings":["Department of Neurosurgery, Massachusetts General Hospital, Somerville, Massachusetts, USA"],"raw_orcid":"https://orcid.org/0009-0004-9063-7984","affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Massachusetts General Hospital, Somerville, Massachusetts, USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015283486","display_name":"Amanda R. Merner","orcid":"https://orcid.org/0000-0001-6450-170X","observed_orcids":["https://orcid.org/0000-0001-6450-170X"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amanda R. Merner","raw_affiliation_strings":["Department of Neurosurgery, Massachusetts General Hospital, Somerville, Massachusetts, USA"],"raw_orcid":"https://orcid.org/0000-0001-6450-170X","affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Massachusetts General Hospital, Somerville, Massachusetts, USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100086961","display_name":"Page M. Trotter","orcid":"https://orcid.org/0000-0003-0307-5465","observed_orcids":["https://orcid.org/0000-0003-0307-5465"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Page M. Trotter","raw_affiliation_strings":["Center for Medical Ethics & Health Policy at Baylor College of Medicine, Houston, Texas, USA"],"raw_orcid":"https://orcid.org/0000-0003-0307-5465","affiliations":[{"raw_affiliation_string":"Center for Medical Ethics & Health Policy at Baylor College of Medicine, Houston, Texas, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113548907","display_name":"Abigail C. Martinez","orcid":"https://orcid.org/0009-0000-2178-7285","observed_orcids":["https://orcid.org/0009-0000-2178-7285"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Abigail C. Martinez","raw_affiliation_strings":["Center for Medical Ethics & Health Policy at Baylor College of Medicine, Houston, Texas, USA"],"raw_orcid":"https://orcid.org/0009-0000-2178-7285","affiliations":[{"raw_affiliation_string":"Center for Medical Ethics & Health Policy at Baylor College of Medicine, Houston, Texas, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100086962","display_name":"Lauren A. Ginn","orcid":"https://orcid.org/0009-0001-5548-9275","observed_orcids":["https://orcid.org/0009-0001-5548-9275"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I74775410","display_name":"Rice University","ror":"https://ror.org/008zs3103","country_code":"US","type":"education","lineage":["https://openalex.org/I74775410"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lauren A. Ginn","raw_affiliation_strings":["Center for Medical Ethics & Health Policy at Baylor College of Medicine, Houston, Texas, USA","Department of Biosciences, Rice University, Houston, Texas, USA"],"raw_orcid":"https://orcid.org/0009-0001-5548-9275","affiliations":[{"raw_affiliation_string":"Center for Medical Ethics & Health Policy at Baylor College of Medicine, Houston, Texas, USA","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"Department of Biosciences, Rice University, Houston, Texas, USA","institution_ids":["https://openalex.org/I74775410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119468070","display_name":"Jonathan Frumovitz","orcid":"https://orcid.org/0009-0007-4488-2534","observed_orcids":["https://orcid.org/0009-0007-4488-2534"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan Frumovitz","raw_affiliation_strings":["Center for Medical Ethics & Health Policy at Baylor College of Medicine, Houston, Texas, USA"],"raw_orcid":"https://orcid.org/0009-0007-4488-2534","affiliations":[{"raw_affiliation_string":"Center for Medical Ethics & Health Policy at Baylor College of Medicine, Houston, Texas, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071956762","display_name":"Daphne M. Ayton","orcid":"https://orcid.org/0000-0002-3822-7310","observed_orcids":["https://orcid.org/0000-0002-3822-7310"]},"institutions":[{"id":"https://openalex.org/I181233156","display_name":"University of Oregon","ror":"https://ror.org/0293rh119","country_code":"US","type":"education","lineage":["https://openalex.org/I181233156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daphne M. Ayton","raw_affiliation_strings":["Department of Psychology, University of Oregon, Oregon, USA"],"raw_orcid":"https://orcid.org/0000-0002-3822-7310","affiliations":[{"raw_affiliation_string":"Department of Psychology, University of Oregon, Oregon, USA","institution_ids":["https://openalex.org/I181233156"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027892391","display_name":"Takahiro Soda","orcid":"https://orcid.org/0000-0001-6268-2965","observed_orcids":["https://orcid.org/0000-0001-6268-2965"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Takahiro Soda","raw_affiliation_strings":["Center for Autism and Neurodevelopment, University of Florida, Gainesville, Florida, USA","Department of Psychiatry & Behavioral Sciences, Baylor College of Medicine Houston, Texas, USA"],"raw_orcid":"https://orcid.org/0000-0001-6268-2965","affiliations":[{"raw_affiliation_string":"Center for Autism and Neurodevelopment, University of Florida, Gainesville, Florida, USA","institution_ids":["https://openalex.org/I33213144"]},{"raw_affiliation_string":"Department of Psychiatry & Behavioral Sciences, Baylor College of Medicine Houston, Texas, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089897759","display_name":"Eric A. Storch","orcid":"https://orcid.org/0000-0002-7631-3703","observed_orcids":["https://orcid.org/0000-0002-7631-3703"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric A. Storch","raw_affiliation_strings":["Department of Psychiatry & Behavioral Sciences, Baylor College of Medicine Houston, Texas, USA"],"raw_orcid":"https://orcid.org/0000-0002-7631-3703","affiliations":[{"raw_affiliation_string":"Department of Psychiatry & Behavioral Sciences, Baylor College of Medicine Houston, Texas, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044108220","display_name":"Stacey Pereira","orcid":"https://orcid.org/0000-0001-6541-3904","observed_orcids":["https://orcid.org/0000-0001-6541-3904"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stacey Pereira","raw_affiliation_strings":["Center for Medical Ethics & Health Policy at Baylor College of Medicine, Houston, Texas, USA"],"raw_orcid":"https://orcid.org/0000-0001-6541-3904","affiliations":[{"raw_affiliation_string":"Center for Medical Ethics & Health Policy at Baylor College of Medicine, Houston, Texas, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024724548","display_name":"Gabriel L\u00e1zaro\u2010Mu\u00f1oz","orcid":"https://orcid.org/0000-0003-1933-9453","observed_orcids":["https://orcid.org/0000-0003-1933-9453"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Gabriel L\u00e1zaro-Mu\u00f1oz","raw_affiliation_strings":["Department of Neurosurgery, Massachusetts General Hospital, Somerville, Massachusetts, USA","Department of Psychiatry, Mass General Hospital, Boston, MA, USA","Harvard Medical School, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0003-1933-9453","affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Massachusetts General Hospital, Somerville, Massachusetts, USA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Department of Psychiatry, Mass General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5024724548"],"corresponding_institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.4253000020980835,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.4253000020980835,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10582","display_name":"Ethics in Clinical Research","score":0.14149999618530273,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11953","display_name":"Neuroethics, Human Enhancement, Biomedical Innovations","score":0.09780000150203705,"subfield":{"id":"https://openalex.org/subfields/1211","display_name":"Philosophy"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polygenic-risk-score","display_name":"polygenic risk score","score":0.8690000176429749},{"id":"https://openalex.org/keywords/mental-disorders","display_name":"mental illness","score":0.9879999756813049},{"id":"https://openalex.org/keywords/patient-perspectives","display_name":"patient perspectives","score":0.859000027179718},{"id":"https://openalex.org/keywords/genetic-testing","display_name":"genetic testing","score":0.9039999842643738},{"id":"https://openalex.org/keywords/genetic-privacy","display_name":"genetic privacy","score":0.48399999737739563},{"id":"https://openalex.org/keywords/stigma","display_name":"stigma","score":0.7459999918937683},{"id":"https://openalex.org/keywords/genetic-discrimination","display_name":"genetic discrimination","score":0.7689999938011169},{"id":"https://openalex.org/keywords/eugenics","display_name":"eugenics","score":0.9739999771118164},{"id":"https://openalex.org/keywords/self-fulfilling-prophecy","display_name":"self-fulfilling prophecy","score":0.8809999823570251},{"id":"https://openalex.org/keywords/child-mental-health","display_name":"child mental health","score":0.4569999873638153}],"concepts":[{"id":"https://openalex.org/C2993137441","wikidata":"https://www.wikidata.org/wiki/Q28135712","display_name":"Polygenic risk score","level":5,"score":0.7967000007629395},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.6754000186920166},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.508899986743927},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.4505000114440918},{"id":"https://openalex.org/C2994403141","wikidata":"https://www.wikidata.org/wiki/Q2976573","display_name":"Psychiatric diagnosis","level":3,"score":0.40639999508857727},{"id":"https://openalex.org/C84201533","wikidata":"https://www.wikidata.org/wiki/Q7256235","display_name":"Psychiatric genetics","level":3,"score":0.3921000063419342},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3813999891281128},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.3215999901294708},{"id":"https://openalex.org/C507311573","wikidata":"https://www.wikidata.org/wiki/Q3510807","display_name":"Psychiatric assessment","level":2,"score":0.3192000091075897},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.3140999972820282},{"id":"https://openalex.org/C12174686","wikidata":"https://www.wikidata.org/wiki/Q1058438","display_name":"Risk assessment","level":2,"score":0.31189998984336853},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.25029999017715454}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.64898/2026.09.24.26363942","doi":"https://doi.org/10.64898/2026.09.24.26363942","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.24.26363942","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/27/2026.09.24.26363942.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},{"id":"pmid:42818454","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42818454","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"medRxiv : the preprint server for health sciences","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13622423","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13622423/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"medRxiv","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.64898/2026.09.24.26363942","doi":"https://doi.org/10.64898/2026.09.24.26363942","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.24.26363942","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/27/2026.09.24.26363942.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5375980098","display_name":"Polygenic Risk Scores in Child and Adolescent Psychiatry: Ethical, Clinical, and Legal Implications","funder_award_id":"R01MH128676","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320309371","display_name":"International OCD Foundation","ror":"https://ror.org/04f3cbh67"},{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7214518631.pdf","grobid_xml":"https://content.openalex.org/works/W7214518631.grobid-xml"},"referenced_works_count":74,"referenced_works":["https://openalex.org/W1963733748","https://openalex.org/W1970447732","https://openalex.org/W1973600209","https://openalex.org/W1981722146","https://openalex.org/W1983743419","https://openalex.org/W2005245306","https://openalex.org/W2007909468","https://openalex.org/W2008779646","https://openalex.org/W2015352059","https://openalex.org/W2023478835","https://openalex.org/W2031095820","https://openalex.org/W2054586858","https://openalex.org/W2060910731","https://openalex.org/W2065403824","https://openalex.org/W2069426489","https://openalex.org/W2075037646","https://openalex.org/W2078635907","https://openalex.org/W2114244610","https://openalex.org/W2129881910","https://openalex.org/W2133674686","https://openalex.org/W2138223431","https://openalex.org/W2139095930","https://openalex.org/W2139204020","https://openalex.org/W2153625321","https://openalex.org/W2163536478","https://openalex.org/W2266871031","https://openalex.org/W2312378080","https://openalex.org/W2322288693","https://openalex.org/W2479559945","https://openalex.org/W2517276995","https://openalex.org/W2614015444","https://openalex.org/W2744940768","https://openalex.org/W2768019144","https://openalex.org/W2796471193","https://openalex.org/W2799351018","https://openalex.org/W2803332630","https://openalex.org/W2884439130","https://openalex.org/W2911487850","https://openalex.org/W2947752575","https://openalex.org/W2950375827","https://openalex.org/W2983765585","https://openalex.org/W3024240210","https://openalex.org/W3028329270","https://openalex.org/W3033040041","https://openalex.org/W3042501831","https://openalex.org/W3089846215","https://openalex.org/W3092074878","https://openalex.org/W3132810618","https://openalex.org/W3145471299","https://openalex.org/W3153216117","https://openalex.org/W3159902810","https://openalex.org/W3164324796","https://openalex.org/W3184690700","https://openalex.org/W3203790657","https://openalex.org/W3208399199","https://openalex.org/W4205208574","https://openalex.org/W4221067412","https://openalex.org/W4223520055","https://openalex.org/W4284668411","https://openalex.org/W4287147673","https://openalex.org/W4296843460","https://openalex.org/W4297502289","https://openalex.org/W4309728751","https://openalex.org/W4318985788","https://openalex.org/W4319316721","https://openalex.org/W4372342583","https://openalex.org/W4375955469","https://openalex.org/W4381487151","https://openalex.org/W4384664113","https://openalex.org/W4400402175","https://openalex.org/W4401264845","https://openalex.org/W4410465357","https://openalex.org/W4411007894","https://openalex.org/W7130402015"],"related_works":["https://openalex.org/W4400402175","https://openalex.org/W7130402015","https://openalex.org/W4410465357","https://openalex.org/W4284668411","https://openalex.org/W4416960065","https://openalex.org/W4404643348","https://openalex.org/W2906999721","https://openalex.org/W4375955469","https://openalex.org/W6986689599","https://openalex.org/W4286836273"],"abstract_inverted_index":{"Polygenic":[0],"risk":[1,11,125],"scores":[2],"(PRS)":[3],"are":[4,18],"rapidly":[5],"developing,":[6],"enabling":[7],"estimates":[8],"of":[9,81,106,118,126,143],"genetic":[10,78],"for":[12,60,108],"developing":[13],"psychiatric":[14,34,49,58,100,144],"disorders.":[15],"Psychiatric":[16],"PRS":[17,59,94,145],"also":[19],"increasingly":[20],"entering":[21],"consumer":[22,149],"and":[23,62,75,83,102,123,148],"clinical":[24,147],"settings.":[25,150],"Yet,":[26],"little":[27],"is":[28],"known":[29],"about":[30],"how":[31],"adults":[32,47],"with":[33,45,48],"disorders":[35,50],"perceive":[36],"their":[37,53,63,109],"potential":[38],"use.":[39],"Here,":[40],"we":[41],"conducted":[42],"semi-structured":[43],"interviews":[44],"29":[46],"to":[51,77,86,136],"examine":[52],"perspectives":[54],"on":[55,139],"hypothetically":[56],"receiving":[57],"themselves":[61],"current":[64],"or":[65],"future":[66],"children.":[67,110],"Key":[68],"themes":[69],"emerged":[70],"around":[71],"perceived":[72],"utility,":[73],"motivations":[74],"deterrents":[76],"testing,":[79],"interpretation":[80],"PRS,":[82],"anticipated":[84],"responses":[85],"results.":[87],"In":[88],"particular,":[89],"participants":[90],"expressed":[91],"hope":[92],"that":[93],"could":[95],"support":[96],"self-understanding,":[97],"inform":[98,137],"better":[99],"care,":[101],"enable":[103],"earlier":[104],"recognition":[105],"difficulties":[107],"Participants":[111],"however":[112],"raised":[113],"multiple":[114],"concerns,":[115],"including":[116],"those":[117],"privacy,":[119],"stigma,":[120],"discrimination,":[121],"eugenics,":[122],"the":[124,140],"self-fulling":[127],"prophecies.":[128],"Together,":[129],"these":[130],"findings":[131],"offer":[132],"critical":[133],"empirical":[134],"evidence":[135],"guidance":[138],"responsible":[141],"use":[142],"in":[146]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2026-09-28T00:00:00"}
