{"id":"https://openalex.org/W7214477159","doi":"https://doi.org/10.13386/j.issn1002-0306.2025100355","title":"Antioxidant Activity and Mechanism of Simulated Digestion Products from Ready-to-Eat Sea Cucumber Body Wall Protein","display_name":"Antioxidant Activity and Mechanism of Simulated Digestion Products from Ready-to-Eat Sea Cucumber Body Wall Protein","publication_year":2026,"publication_date":"2026-10-01","ids":{"openalex":"https://openalex.org/W7214477159","doi":"https://doi.org/10.13386/j.issn1002-0306.2025100355"},"language":"zh","primary_location":{"id":"pmh:oai:doaj.org/article:74033b35307446f4a8059d06e3f37651","doi":"https://doi.org/10.13386/j.issn1002-0306.2025100355","is_oa":false,"landing_page_url":"https://doaj.org/article/74033b35307446f4a8059d06e3f37651","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Shipin gongye ke-ji, Vol 47, Iss 19, Pp 202-215 (2026)","raw_type":"article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["doaj"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5152975770","display_name":"Long LI","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Long LI","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5153005422","display_name":"Zhiyu FU","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhiyu FU","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5152996525","display_name":"Yujun LIU","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yujun LIU","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5152965857","display_name":"Shikuan JIN","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shikuan JIN","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5152993554","display_name":"Yuqi ZHENG","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yuqi ZHENG","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062594420","display_name":"Hanyu Wang","orcid":"https://orcid.org/0009-0009-0697-4256","observed_orcids":["https://orcid.org/0009-0009-0697-4256"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hanyu WANG","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5153008736","display_name":"Zhiyuan SONG","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhiyuan SONG","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5152985424","display_name":"Di YU","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Di YU","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5152961415","display_name":"Hai CHI","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hai CHI","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5152957071","display_name":"Jie ZHENG","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jie ZHENG","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11561","display_name":"Protein Hydrolysis and Bioactive Peptides","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11561","display_name":"Protein Hydrolysis and Bioactive Peptides","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12841","display_name":"Echinoderm biology and ecology","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11390","display_name":"Seaweed-derived Bioactive Compounds","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antioxidant-peptides","display_name":"antioxidant peptides","score":0.8240000009536743},{"id":"https://openalex.org/keywords/in-vitro-digestion","display_name":"in vitro digestion","score":0.8299999833106995},{"id":"https://openalex.org/keywords/gastrointestinal-digestion","display_name":"gastrointestinal digestion","score":0.546999990940094},{"id":"https://openalex.org/keywords/collagen","display_name":"collagen","score":0.5619999766349792},{"id":"https://openalex.org/keywords/degree-of-hydrolysis","display_name":"degree of hydrolysis","score":0.8769999742507935},{"id":"https://openalex.org/keywords/peptide-fractions","display_name":"peptide fractions","score":0.4090000092983246},{"id":"https://openalex.org/keywords/abts-assay","display_name":"ABTS radical scavenging","score":0.7990000247955322},{"id":"https://openalex.org/keywords/ferrous-ion-chelation","display_name":"ferrous ion chelation","score":0.9599999785423279},{"id":"https://openalex.org/keywords/molecular-docking","display_name":"molecular docking","score":0.7990000247955322},{"id":"https://openalex.org/keywords/dietary-antioxidants","display_name":"dietary antioxidants","score":0.6669999957084656},{"id":"https://openalex.org/keywords/essential-amino-acids","display_name":"essential amino acids","score":0.8709999918937683}],"concepts":[{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.8513000011444092},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7739999890327454},{"id":"https://openalex.org/C2776093933","wikidata":"https://www.wikidata.org/wiki/Q127470","display_name":"Sea cucumber","level":2,"score":0.751800000667572},{"id":"https://openalex.org/C2775832776","wikidata":"https://www.wikidata.org/wiki/Q65122087","display_name":"Ferrous","level":2,"score":0.6216999888420105},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.6061999797821045},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.5527999997138977},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.5055000185966492},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.4611000120639801},{"id":"https://openalex.org/C94412978","wikidata":"https://www.wikidata.org/wiki/Q103135","display_name":"Hydrolysis","level":2,"score":0.4514000117778778},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.44940000772476196},{"id":"https://openalex.org/C2781357212","wikidata":"https://www.wikidata.org/wiki/Q5275608","display_name":"Digestion (alchemy)","level":2,"score":0.3752000033855438},{"id":"https://openalex.org/C197404232","wikidata":"https://www.wikidata.org/wiki/Q319827","display_name":"Chelation","level":2,"score":0.3610999882221222},{"id":"https://openalex.org/C58121356","wikidata":"https://www.wikidata.org/wiki/Q182854","display_name":"Molecular mass","level":3,"score":0.3497999906539917},{"id":"https://openalex.org/C125235067","wikidata":"https://www.wikidata.org/wiki/Q128700","display_name":"Cell wall","level":2,"score":0.3262999951839447},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.3118000030517578},{"id":"https://openalex.org/C2993539680","wikidata":"https://www.wikidata.org/wiki/Q902552","display_name":"Antioxidant capacity","level":3,"score":0.29739999771118164},{"id":"https://openalex.org/C116073593","wikidata":"https://www.wikidata.org/wiki/Q864491","display_name":"Biological activity","level":3,"score":0.2842999994754791},{"id":"https://openalex.org/C53270655","wikidata":"https://www.wikidata.org/wiki/Q5381536","display_name":"Enzymatic hydrolysis","level":3,"score":0.25279998779296875},{"id":"https://openalex.org/C62614982","wikidata":"https://www.wikidata.org/wiki/Q904984","display_name":"Protein secondary structure","level":2,"score":0.2526000142097473}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:doaj.org/article:74033b35307446f4a8059d06e3f37651","doi":"https://doi.org/10.13386/j.issn1002-0306.2025100355","is_oa":false,"landing_page_url":"https://doaj.org/article/74033b35307446f4a8059d06e3f37651","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Shipin gongye ke-ji, Vol 47, Iss 19, Pp 202-215 (2026)","raw_type":"article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Life below water","id":"https://metadata.un.org/sdg/14","score":1.0},{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.40450000762939453}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4416102056","https://openalex.org/W2361715027","https://openalex.org/W2990008728","https://openalex.org/W4394768050","https://openalex.org/W7204645108","https://openalex.org/W2083696618","https://openalex.org/W2366467731","https://openalex.org/W7163166029","https://openalex.org/W2410955529","https://openalex.org/W2991087935"],"abstract_inverted_index":{"To":[0],"explore":[1],"the":[2,17,28,41,57,78,103,125,171,177,191],"antioxidant":[3,29,46,100,203,218],"activity":[4,30,114],"of":[5,20,31,43,45,61,68,80,82,127,179],"ready-to-eat":[6,21,62,198],"sea":[7,22,63,199],"cucumber\u2014a":[8],"mainstream":[9],"commercial":[10],"product\u2014following":[11],"digestion,":[12,77,210],"this":[13],"study":[14],"first":[15],"characterized":[16],"nutritional":[18,59],"composition":[19],"cucumber,":[23],"and":[24,115,124,152,187],"focused":[25],"on":[26],"analyzing":[27],"its":[32,202,212],"protein":[33,66,85],"after":[34,205],"in":[35,74,99,206],"vitro":[36,75,207],"simulated":[37,76,208],"oral-gastrointestinal":[38,209],"digestion.":[39],"Finally,":[40],"mechanism":[42],"action":[44],"peptides":[47,154,168],"was":[48,65,71,86,131,143],"explored":[49],"through":[50],"molecular":[51,93],"docking.":[52],"The":[53],"results":[54,164],"showed":[55],"that":[56,166,197],"primary":[58,192],"component":[60],"cucumber":[64,200],"(69.52%),":[67],"which":[69],"67.02%":[70],"collagen.":[72],"Following":[73],"degree":[79],"hydrolysis":[81],"body":[83],"wall":[84],"75.69%.":[87],"Three":[88],"peptide":[89],"fractions":[90,136,147],"within":[91,181],"different":[92],"weight":[94],"(MW)":[95],"exhibited":[96],"concentration-dependent":[97],"increases":[98],"capacity.":[101],"Notably,":[102],"fraction":[104],"with":[105,148,184],"MW":[106,149],"<3":[107,150],"kDa":[108],"displayed":[109],"significantly":[110,132],"higher":[111,133],"ABTS+\u00b7":[112],"scavenging":[113],"ferrous":[116],"ion":[117],"chelating":[118],"capacity":[119,204],"even":[120],"at":[121],"low":[122],"concentrations,":[123],"proportion":[126],"essential":[128],"amino":[129],"acids":[130],"than":[134],"other":[135],"(P<0.05).":[137],"Liquid":[138],"chromatography-tandem":[139],"mass":[140],"spectrometry":[141],"(LC-MS/MS)":[142],"employed":[144],"to":[145],"identify":[146],"kDa,":[151],"36":[153],"were":[155],"selected":[156],"for":[157],"subsequent":[158],"analysis":[159],"following":[160],"screening.":[161],"Molecular":[162],"docking":[163],"indicated":[165],"all":[167],"could":[169],"activate":[170],"Keap1-Nrf2-ARE":[172],"signaling":[173],"pathways":[174],"via":[175],"occupying":[176],"site":[178],"Nrf2":[180],"Keap1's":[182],"pocket,":[183],"hydrogen":[185],"bonding":[186],"hydrophobic":[188],"interaction":[189],"being":[190],"forces.":[193],"These":[194],"findings":[195],"confirm":[196],"maintains":[201],"supporting":[211],"potential":[213],"use":[214],"as":[215],"a":[216],"dietary":[217],"source.":[219]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2026-09-27T00:00:00"}