{"id":"https://openalex.org/W7214298271","doi":"https://doi.org/10.64898/2026.09.21.749940","title":"A Community-Driven Single-Cell PBMC Reference Integrating Landmark Datasets Spanning Health and Disease","display_name":"A Community-Driven Single-Cell PBMC Reference Integrating Landmark Datasets Spanning Health and Disease","publication_year":2026,"publication_date":"2026-09-25","ids":{"openalex":"https://openalex.org/W7214298271","doi":"https://doi.org/10.64898/2026.09.21.749940"},"language":"en","primary_location":{"id":"doi:10.64898/2026.09.21.749940","doi":"https://doi.org/10.64898/2026.09.21.749940","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.21.749940","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/09/25/2026.09.21.749940.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2026/09/25/2026.09.21.749940.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000849812","display_name":"Ana-Maria Cujba","orcid":"https://orcid.org/0000-0003-3917-6751","observed_orcids":["https://orcid.org/0000-0003-3917-6751"]},"institutions":[{"id":"https://openalex.org/I21196054","display_name":"Wellcome/MRC Cambridge Stem Cell Institute","ror":"https://ror.org/05nz0zp31","country_code":"GB","type":"facility","lineage":["https://openalex.org/I21196054","https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I87048295","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ana-Maria Cujba","raw_affiliation_strings":["Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK"],"raw_orcid":"https://orcid.org/0000-0003-3917-6751","affiliations":[{"raw_affiliation_string":"Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I21196054","https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081241929","display_name":"Sergio Aguilar-Fern\u00e1ndez","orcid":"https://orcid.org/0000-0002-8869-1066","observed_orcids":["https://orcid.org/0000-0002-8869-1066"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sergio Aguilar-Fernandez","raw_affiliation_strings":["Broad Institute of MIT and Harvard, Cambridge, MA, USA","Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","Harvard Medical School, Boston, MA, USA","Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-8869-1066","affiliations":[{"raw_affiliation_string":"Broad Institute of MIT and Harvard, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265"]},{"raw_affiliation_string":"Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5143771554","display_name":"Adrien Antoinette","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adrien Antoinette","raw_affiliation_strings":["Broad Institute of MIT and Harvard, Cambridge, MA, USA","Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","Harvard Medical School, Boston, MA, USA","Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Broad Institute of MIT and Harvard, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265"]},{"raw_affiliation_string":"Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122342296","display_name":"Wamia Said","orcid":"https://orcid.org/0009-0006-5513-7372","observed_orcids":["https://orcid.org/0009-0006-5513-7372"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wamia Said","raw_affiliation_strings":["Broad Institute of MIT and Harvard, Cambridge, MA, USA","Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Broad Institute of MIT and Harvard, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265"]},{"raw_affiliation_string":"Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082173864","display_name":"Michaela M\u00fcller","orcid":"https://orcid.org/0000-0002-1401-1785","observed_orcids":["https://orcid.org/0000-0002-1401-1785"]},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Munich","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]},{"id":"https://openalex.org/I4405263983","display_name":"Institute of Computational Biology","ror":"https://ror.org/00kg2yq63","country_code":"DE","type":"education","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672","https://openalex.org/I4405263983"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Michaela F. Mueller","raw_affiliation_strings":["Institute of Computational Biology, Helmholtz Munich, Neuherberg/Munich, Germany","TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany; School of Computation, Information and Technology, Technical University of Munich, Munich, Germany"],"raw_orcid":"https://orcid.org/0000-0002-1401-1785","affiliations":[{"raw_affiliation_string":"Institute of Computational Biology, Helmholtz Munich, Neuherberg/Munich, Germany","institution_ids":["https://openalex.org/I3018134672","https://openalex.org/I4405263983"]},{"raw_affiliation_string":"TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany; School of Computation, Information and Technology, Technical University of Munich, Munich, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013925437","display_name":"Kian Hong Kock","orcid":"https://orcid.org/0000-0001-5760-8111","observed_orcids":["https://orcid.org/0000-0001-5760-8111"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I66068411","display_name":"Genome Institute of Singapore","ror":"https://ror.org/05k8wg936","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I66068411"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Kian Hong Kock","raw_affiliation_strings":["Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Republic of Singapore"],"raw_orcid":"https://orcid.org/0000-0001-5760-8111","affiliations":[{"raw_affiliation_string":"Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Republic of Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I66068411"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079329619","display_name":"Jacquelyn Nestor","orcid":"https://orcid.org/0000-0002-7787-5476","observed_orcids":["https://orcid.org/0000-0002-7787-5476"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jacquelyn Nestor","raw_affiliation_strings":["Broad Institute of MIT and Harvard, Cambridge, MA, USA","Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","Harvard Medical School, Boston, MA, USA","Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-7787-5476","affiliations":[{"raw_affiliation_string":"Broad Institute of MIT and Harvard, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265"]},{"raw_affiliation_string":"Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093085827","display_name":"Radhika Sonthalia","orcid":"https://orcid.org/0009-0007-0992-871X","observed_orcids":["https://orcid.org/0009-0007-0992-871X"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I66068411","display_name":"Genome Institute of Singapore","ror":"https://ror.org/05k8wg936","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I66068411"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Radhika Sonthalia","raw_affiliation_strings":["Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Republic of Singapore"],"raw_orcid":"https://orcid.org/0009-0007-0992-871X","affiliations":[{"raw_affiliation_string":"Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Republic of Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I66068411"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093085826","display_name":"Eliora Violain Buyamin","orcid":"https://orcid.org/0009-0003-4557-8420","observed_orcids":["https://orcid.org/0009-0003-4557-8420"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I2802476451","display_name":"Wellcome Sanger Institute","ror":"https://ror.org/05cy4wa09","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2802476451","https://openalex.org/I87048295"]},{"id":"https://openalex.org/I66068411","display_name":"Genome Institute of Singapore","ror":"https://ror.org/05k8wg936","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I66068411"]}],"countries":["GB","SG"],"is_corresponding":false,"raw_author_name":"Eliora V. Buyamin","raw_affiliation_strings":["Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Republic of Singapore","Wellcome Sanger Institute, Cambridge, UK"],"raw_orcid":"https://orcid.org/0009-0003-4557-8420","affiliations":[{"raw_affiliation_string":"Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Republic of Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I66068411"]},{"raw_affiliation_string":"Wellcome Sanger Institute, Cambridge, UK","institution_ids":["https://openalex.org/I2802476451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5137276588","display_name":"Pragya Rawat","orcid":"https://orcid.org/0009-0004-2649-5117","observed_orcids":["https://orcid.org/0009-0004-2649-5117"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pragya Rawat","raw_affiliation_strings":["Broad Institute of MIT and Harvard, Cambridge, MA, USA","Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0009-0004-2649-5117","affiliations":[{"raw_affiliation_string":"Broad Institute of MIT and Harvard, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265"]},{"raw_affiliation_string":"Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051727694","display_name":"Alexander V. Predeus","orcid":"https://orcid.org/0000-0002-2750-1599","observed_orcids":["https://orcid.org/0000-0002-2750-1599"]},"institutions":[{"id":"https://openalex.org/I2802476451","display_name":"Wellcome Sanger Institute","ror":"https://ror.org/05cy4wa09","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2802476451","https://openalex.org/I87048295"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alexander Predeus","raw_affiliation_strings":["Wellcome Sanger Institute, Cambridge, UK"],"raw_orcid":"https://orcid.org/0000-0002-2750-1599","affiliations":[{"raw_affiliation_string":"Wellcome Sanger Institute, Cambridge, UK","institution_ids":["https://openalex.org/I2802476451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032423737","display_name":"Lorenz Kretschmer","orcid":"https://orcid.org/0000-0003-0987-8429","observed_orcids":["https://orcid.org/0000-0003-0987-8429"]},"institutions":[{"id":"https://openalex.org/I21196054","display_name":"Wellcome/MRC Cambridge Stem Cell Institute","ror":"https://ror.org/05nz0zp31","country_code":"GB","type":"facility","lineage":["https://openalex.org/I21196054","https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I87048295","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Lorenz Kretschmer","raw_affiliation_strings":["Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK"],"raw_orcid":"https://orcid.org/0000-0003-0987-8429","affiliations":[{"raw_affiliation_string":"Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I21196054","https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060485924","display_name":"Lijiang Fei","orcid":"https://orcid.org/0000-0002-2066-7297","observed_orcids":["https://orcid.org/0000-0002-2066-7297"]},"institutions":[{"id":"https://openalex.org/I21196054","display_name":"Wellcome/MRC Cambridge Stem Cell Institute","ror":"https://ror.org/05nz0zp31","country_code":"GB","type":"facility","lineage":["https://openalex.org/I21196054","https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I87048295","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Lijiang Fei","raw_affiliation_strings":["Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK"],"raw_orcid":"https://orcid.org/0000-0002-2066-7297","affiliations":[{"raw_affiliation_string":"Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I21196054","https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006194206","display_name":"Kamil Slowikowski","orcid":"https://orcid.org/0000-0002-2843-6370","observed_orcids":["https://orcid.org/0000-0002-2843-6370"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kamil Slowikowski","raw_affiliation_strings":["Broad Institute of MIT and Harvard, Cambridge, MA, USA","Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","Harvard Medical School, Boston, MA, USA","Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-2843-6370","affiliations":[{"raw_affiliation_string":"Broad Institute of MIT and Harvard, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265"]},{"raw_affiliation_string":"Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Pritha Sen","orcid":"https://orcid.org/0000-0002-9102-4045","observed_orcids":["https://orcid.org/0000-0002-9102-4045"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT","US"],"is_corresponding":false,"raw_author_name":"Pritha Sen","raw_affiliation_strings":["Broad Institute of MIT and Harvard, Cambridge, MA, USA","Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","Harvard Medical School, Boston, MA, USA","Sapienza University of Rome, Rome, Italy"],"raw_orcid":"https://orcid.org/0000-0002-9102-4045","affiliations":[{"raw_affiliation_string":"Broad Institute of MIT and Harvard, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265"]},{"raw_affiliation_string":"Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Sapienza University of Rome, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076153420","display_name":"Christopher V. Cosgriff","orcid":"https://orcid.org/0000-0003-1980-241X","observed_orcids":["https://orcid.org/0000-0003-1980-241X"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher V. Cosgriff","raw_affiliation_strings":["Broad Institute of MIT and Harvard, Cambridge, MA, USA","Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","Harvard Medical School, Boston, MA, USA","Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Broad Institute of MIT and Harvard, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265"]},{"raw_affiliation_string":"Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5152908481","display_name":"MGH COVID-19 Collection & Processing Team","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"MGH COVID-19 Collection & Processing Team","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5136973976","display_name":"Olli Dufva","orcid":"https://orcid.org/0000-0002-8084-0282","observed_orcids":["https://orcid.org/0000-0002-8084-0282"]},"institutions":[{"id":"https://openalex.org/I21196054","display_name":"Wellcome/MRC Cambridge Stem Cell Institute","ror":"https://ror.org/05nz0zp31","country_code":"GB","type":"facility","lineage":["https://openalex.org/I21196054","https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I87048295","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I2802476451","display_name":"Wellcome Sanger Institute","ror":"https://ror.org/05cy4wa09","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2802476451","https://openalex.org/I87048295"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Olli Dufva","raw_affiliation_strings":["Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK","Wellcome Sanger Institute, Cambridge, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I21196054","https://openalex.org/I241749"]},{"raw_affiliation_string":"Wellcome Sanger Institute, Cambridge, UK","institution_ids":["https://openalex.org/I2802476451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5152820371","display_name":"Mohamad Askari","orcid":"https://orcid.org/0009-0007-3795-8959","observed_orcids":["https://orcid.org/0009-0007-3795-8959"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Mohamad Askari","raw_affiliation_strings":["Sapienza University of Rome, Rome, Italy"],"raw_orcid":"https://orcid.org/0009-0007-3795-8959","affiliations":[{"raw_affiliation_string":"Sapienza University of Rome, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079993874","display_name":"Kyle Kimler","orcid":"https://orcid.org/0000-0003-4735-9064","observed_orcids":["https://orcid.org/0000-0003-4735-9064"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kyle Kimler","raw_affiliation_strings":["Broad Institute of MIT and Harvard, Cambridge, MA, USA","Cell Discovery Network, Boston Children\u2019s Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0003-4735-9064","affiliations":[{"raw_affiliation_string":"Broad Institute of MIT and Harvard, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265"]},{"raw_affiliation_string":"Cell Discovery Network, Boston Children\u2019s Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I1288882113"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024525909","display_name":"Mary Futey","orcid":"https://orcid.org/0009-0005-7163-2747","observed_orcids":["https://orcid.org/0009-0005-7163-2747"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary Futey","raw_affiliation_strings":["Broad Institute of MIT and Harvard, Cambridge, MA, USA","Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0009-0005-7163-2747","affiliations":[{"raw_affiliation_string":"Broad Institute of MIT and Harvard, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265"]},{"raw_affiliation_string":"Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063346622","display_name":"Ida Zucchi","orcid":"https://orcid.org/0000-0002-4900-7575","observed_orcids":["https://orcid.org/0000-0002-4900-7575"]},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ida Zucchi","raw_affiliation_strings":["European Bioinformatics Institute (EMBL-EBI), Cambridge, UK"],"raw_orcid":"https://orcid.org/0000-0002-4900-7575","affiliations":[{"raw_affiliation_string":"European Bioinformatics Institute (EMBL-EBI), Cambridge, UK","institution_ids":["https://openalex.org/I1303153112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103017848","display_name":"Arsenios Chatzigeorgiou","orcid":"https://orcid.org/0000-0002-0608-0553","observed_orcids":["https://orcid.org/0000-0002-0608-0553"]},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Arsenios Chatzigeorgiou","raw_affiliation_strings":["European Bioinformatics Institute (EMBL-EBI), Cambridge, UK"],"raw_orcid":"https://orcid.org/0000-0002-0608-0553","affiliations":[{"raw_affiliation_string":"European Bioinformatics Institute (EMBL-EBI), Cambridge, UK","institution_ids":["https://openalex.org/I1303153112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044692181","display_name":"Parisa Nejad","orcid":"https://orcid.org/0000-0002-3163-0115","observed_orcids":["https://orcid.org/0000-0002-3163-0115"]},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Parisa Nejad","raw_affiliation_strings":["UC Santa Cruz Genomics Institute, Santa Cruz, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UC Santa Cruz Genomics Institute, Santa Cruz, CA, USA","institution_ids":["https://openalex.org/I185103710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5152950791","display_name":"Liying Jin","orcid":"https://orcid.org/0009-0001-4442-7298","observed_orcids":["https://orcid.org/0009-0001-4442-7298"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4405264228","display_name":"Kennedy Institute of Rheumatology","ror":"https://ror.org/01ahsqc77","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149","https://openalex.org/I4405264228"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Liying Jin","raw_affiliation_strings":["Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK"],"raw_orcid":"https://orcid.org/0009-0001-4442-7298","affiliations":[{"raw_affiliation_string":"Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I40120149","https://openalex.org/I4405264228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049550272","display_name":"Blake Bowen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136750679","display_name":"Garvan Institute of Medical Research","ror":"https://ror.org/01b3dvp57","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I136750679","https://openalex.org/I4210087284"]},{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Blake Bowen","raw_affiliation_strings":["Cellular Genomics Futures Institute, University of New South Wales, Sydney, Australia","Garvan Institute for Medical Research, Darlinghurst, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cellular Genomics Futures Institute, University of New South Wales, Sydney, Australia","institution_ids":["https://openalex.org/I31746571"]},{"raw_affiliation_string":"Garvan Institute for Medical Research, Darlinghurst, Australia","institution_ids":["https://openalex.org/I136750679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045591497","display_name":"Andrian Yang","orcid":"https://orcid.org/0000-0002-8327-8096","observed_orcids":["https://orcid.org/0000-0002-8327-8096"]},"institutions":[{"id":"https://openalex.org/I21196054","display_name":"Wellcome/MRC Cambridge Stem Cell Institute","ror":"https://ror.org/05nz0zp31","country_code":"GB","type":"facility","lineage":["https://openalex.org/I21196054","https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I87048295","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrian Yang","raw_affiliation_strings":["Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK"],"raw_orcid":"https://orcid.org/0000-0002-8327-8096","affiliations":[{"raw_affiliation_string":"Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I21196054","https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035630262","display_name":"Rik G.H. Lindeboom","orcid":"https://orcid.org/0000-0002-3660-504X","observed_orcids":["https://orcid.org/0000-0002-3660-504X"]},"institutions":[{"id":"https://openalex.org/I2898336195","display_name":"The Netherlands Cancer Institute","ror":"https://ror.org/03xqtf034","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2898336195"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Rik G. H. Lindeboom","raw_affiliation_strings":["The Netherlands Cancer Institute, Amsterdam, The Netherlands"],"raw_orcid":"https://orcid.org/0000-0002-3660-504X","affiliations":[{"raw_affiliation_string":"The Netherlands Cancer Institute, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2898336195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062744561","display_name":"Rachelly Normand","orcid":"https://orcid.org/0000-0002-5628-5450","observed_orcids":["https://orcid.org/0000-0002-5628-5450"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rachelly Normand","raw_affiliation_strings":["Broad Institute of MIT and Harvard, Cambridge, MA, USA","Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","Harvard Medical School, Boston, MA, USA","Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-5628-5450","affiliations":[{"raw_affiliation_string":"Broad Institute of MIT and Harvard, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265"]},{"raw_affiliation_string":"Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104427286","display_name":"Stathis Megas","orcid":"https://orcid.org/0000-0002-2038-3040","observed_orcids":["https://orcid.org/0000-0002-2038-3040"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Stathis Megas","raw_affiliation_strings":["Medical University of Vienna, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051765798","display_name":"Yoshinari Ando","orcid":"https://orcid.org/0000-0002-8128-6201","observed_orcids":["https://orcid.org/0000-0002-8128-6201"]},"institutions":[{"id":"https://openalex.org/I4210150921","display_name":"RIKEN Center for Integrative Medical Sciences","ror":"https://ror.org/04mb6s476","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210110652","https://openalex.org/I4210150921"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshinari Ando","raw_affiliation_strings":["RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan"],"raw_orcid":"https://orcid.org/0000-0002-8128-6201","affiliations":[{"raw_affiliation_string":"RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan","institution_ids":["https://openalex.org/I4210150921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103062829","display_name":"A Chatterjee","orcid":"https://orcid.org/0000-0002-0619-0728","observed_orcids":["https://orcid.org/0000-0002-0619-0728"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ankita Chatterjee","raw_affiliation_strings":["John C. Martin Centre for Liver Research and Innovations, Sonarpur, Kolkata, India"],"raw_orcid":"https://orcid.org/0000-0002-0619-0728","affiliations":[{"raw_affiliation_string":"John C. Martin Centre for Liver Research and Innovations, Sonarpur, Kolkata, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101701220","display_name":"Jong-Eun Park","orcid":"https://orcid.org/0000-0002-1687-2423","observed_orcids":["https://orcid.org/0000-0002-1687-2423"]},"institutions":[{"id":"https://openalex.org/I157485424","display_name":"Korea Advanced Institute of Science and Technology","ror":"https://ror.org/05apxxy63","country_code":"KR","type":"education","lineage":["https://openalex.org/I157485424"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jong-Eun Park","raw_affiliation_strings":["Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Republic of Korea","institution_ids":["https://openalex.org/I157485424"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105840935","display_name":"Partha P. Majumder","orcid":"https://orcid.org/0000-0001-7009-7360","observed_orcids":["https://orcid.org/0000-0001-7009-7360"]},"institutions":[{"id":"https://openalex.org/I6498739","display_name":"Indian Statistical Institute","ror":"https://ror.org/00q2w1j53","country_code":"IN","type":"education","lineage":["https://openalex.org/I6498739"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Partha P. Majumder","raw_affiliation_strings":["Indian Statistical Institute, Kolkata, India","John C. Martin Centre for Liver Research and Innovations, Sonarpur, Kolkata, India"],"raw_orcid":"https://orcid.org/0000-0001-7009-7360","affiliations":[{"raw_affiliation_string":"Indian Statistical Institute, Kolkata, India","institution_ids":["https://openalex.org/I6498739"]},{"raw_affiliation_string":"John C. Martin Centre for Liver Research and Innovations, Sonarpur, Kolkata, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010711716","display_name":"Ponpan Matangkasombut","orcid":"https://orcid.org/0000-0003-0101-4386","observed_orcids":["https://orcid.org/0000-0003-0101-4386"]},"institutions":[{"id":"https://openalex.org/I25399158","display_name":"Mahidol University","ror":"https://ror.org/01znkr924","country_code":"TH","type":"education","lineage":["https://openalex.org/I25399158"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Ponpan Matangkasombut","raw_affiliation_strings":["Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand","Single-cell Omics and Systems Biology of Diseases Research Unit, Faculty of Science, Mahidol University, Bangkok, Thailand"],"raw_orcid":"https://orcid.org/0000-0003-0101-4386","affiliations":[{"raw_affiliation_string":"Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand","institution_ids":["https://openalex.org/I25399158"]},{"raw_affiliation_string":"Single-cell Omics and Systems Biology of Diseases Research Unit, Faculty of Science, Mahidol University, Bangkok, Thailand","institution_ids":["https://openalex.org/I25399158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068229903","display_name":"Varodom Charoensawan","orcid":"https://orcid.org/0000-0002-2199-4126","observed_orcids":["https://orcid.org/0000-0002-2199-4126"]},"institutions":[{"id":"https://openalex.org/I1332387789","display_name":"Siriraj Hospital","ror":"https://ror.org/0331zs648","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I1332387789"]},{"id":"https://openalex.org/I25399158","display_name":"Mahidol University","ror":"https://ror.org/01znkr924","country_code":"TH","type":"education","lineage":["https://openalex.org/I25399158"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Varodom Charoensawan","raw_affiliation_strings":["Department of Biochemistry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand","Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok, Thailand","Integrative Computational BioScience (ICBS) center, Mahidol University, Nakhon Pathom, Thailand","Single-cell Omics and Systems Biology of Diseases Research Unit, Faculty of Science, Mahidol University, Bangkok, Thailand","Siriraj Genomics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand"],"raw_orcid":"https://orcid.org/0000-0002-2199-4126","affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand","institution_ids":["https://openalex.org/I1332387789","https://openalex.org/I25399158"]},{"raw_affiliation_string":"Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok, Thailand","institution_ids":["https://openalex.org/I25399158"]},{"raw_affiliation_string":"Integrative Computational BioScience (ICBS) center, Mahidol University, Nakhon Pathom, Thailand","institution_ids":["https://openalex.org/I25399158"]},{"raw_affiliation_string":"Single-cell Omics and Systems Biology of Diseases Research Unit, Faculty of Science, Mahidol University, Bangkok, Thailand","institution_ids":["https://openalex.org/I25399158"]},{"raw_affiliation_string":"Siriraj Genomics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand","institution_ids":["https://openalex.org/I1332387789","https://openalex.org/I25399158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007530779","display_name":"Jay W. Shin","orcid":"https://orcid.org/0000-0003-4037-3533","observed_orcids":["https://orcid.org/0000-0003-4037-3533"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I4210150921","display_name":"RIKEN Center for Integrative Medical Sciences","ror":"https://ror.org/04mb6s476","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210110652","https://openalex.org/I4210150921"]},{"id":"https://openalex.org/I66068411","display_name":"Genome Institute of Singapore","ror":"https://ror.org/05k8wg936","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I66068411"]}],"countries":["JP","SG"],"is_corresponding":false,"raw_author_name":"Jay W. Shin","raw_affiliation_strings":["Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Republic of Singapore","Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Republic of Singapore","Laboratory for Advanced Genomics Circuit, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan"],"raw_orcid":"https://orcid.org/0000-0003-4037-3533","affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Republic of Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Republic of Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I66068411"]},{"raw_affiliation_string":"Laboratory for Advanced Genomics Circuit, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan","institution_ids":["https://openalex.org/I4210150921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003283147","display_name":"Woong\u2010Yang Park","orcid":"https://orcid.org/0000-0003-4234-0380","observed_orcids":["https://orcid.org/0000-0003-4234-0380"]},"institutions":[{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Woong-Yang Park","raw_affiliation_strings":["Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0003-4234-0380","affiliations":[{"raw_affiliation_string":"Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea","institution_ids":["https://openalex.org/I848706"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138126357","display_name":"Asian Immune Diversity Atlas Network","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Asian Immune Diversity Atlas (AIDA) Network","raw_affiliation_strings":["Department of Medicine , Massachusetts General Hospital , Boston , MA , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine , Massachusetts General Hospital , Boston , MA , USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087953869","display_name":"Stephen Nicholas Sansom","orcid":"https://orcid.org/0000-0003-4569-8513","observed_orcids":["https://orcid.org/0000-0003-4569-8513"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4405264228","display_name":"Kennedy Institute of Rheumatology","ror":"https://ror.org/01ahsqc77","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149","https://openalex.org/I4405264228"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stephen Sansom","raw_affiliation_strings":["Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I40120149","https://openalex.org/I4405264228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017318024","display_name":"Berthold G\u00f6ttgens","orcid":"https://orcid.org/0000-0001-6302-5705","observed_orcids":["https://orcid.org/0000-0001-6302-5705"]},"institutions":[{"id":"https://openalex.org/I21196054","display_name":"Wellcome/MRC Cambridge Stem Cell Institute","ror":"https://ror.org/05nz0zp31","country_code":"GB","type":"facility","lineage":["https://openalex.org/I21196054","https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I87048295","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Berthold G\u00f6ttgens","raw_affiliation_strings":["Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK","Department of Haematology, University of Cambridge, Cambridge, UK"],"raw_orcid":"https://orcid.org/0000-0001-6302-5705","affiliations":[{"raw_affiliation_string":"Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I21196054","https://openalex.org/I241749"]},{"raw_affiliation_string":"Department of Haematology, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063458641","display_name":"Joseph E. Powell","orcid":"https://orcid.org/0000-0002-5070-4124","observed_orcids":["https://orcid.org/0000-0002-5070-4124","https://orcid.org/0000-0001-9031-6356"]},"institutions":[{"id":"https://openalex.org/I136750679","display_name":"Garvan Institute of Medical Research","ror":"https://ror.org/01b3dvp57","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I136750679","https://openalex.org/I4210087284"]},{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4405264228","display_name":"Kennedy Institute of Rheumatology","ror":"https://ror.org/01ahsqc77","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149","https://openalex.org/I4405264228"]}],"countries":["AU","GB"],"is_corresponding":false,"raw_author_name":"Joseph E. Powell","raw_affiliation_strings":["Garvan Institute for Medical Research, Darlinghurst, Australia","Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK"],"raw_orcid":"https://orcid.org/0000-0002-5070-4124","affiliations":[{"raw_affiliation_string":"Garvan Institute for Medical Research, Darlinghurst, Australia","institution_ids":["https://openalex.org/I136750679"]},{"raw_affiliation_string":"Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I40120149","https://openalex.org/I4405264228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103221881","display_name":"Lloyd Bod","orcid":"https://orcid.org/0000-0001-8124-0863","observed_orcids":["https://orcid.org/0000-0001-8124-0863","https://orcid.org/0000-0003-3663-2571"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lloyd Bod","raw_affiliation_strings":["Broad Institute of MIT and Harvard, Cambridge, MA, USA","Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","Harvard Medical School, Boston, MA, USA","Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0001-8124-0863","affiliations":[{"raw_affiliation_string":"Broad Institute of MIT and Harvard, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265"]},{"raw_affiliation_string":"Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069693450","display_name":"Holger Heyn","orcid":"https://orcid.org/0000-0002-3276-1889","observed_orcids":["https://orcid.org/0000-0002-3276-1889"]},"institutions":[{"id":"https://openalex.org/I4210142206","display_name":"Centro Nacional de An\u00e1lisis Gen\u00f3mico","ror":"https://ror.org/03mynna02","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210142206"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Holger Heyn","raw_affiliation_strings":["Centro Nacional de An\u00e1lisis Gen\u00f3mico (CNAG), Barcelona, Spain"],"raw_orcid":"https://orcid.org/0000-0002-3276-1889","affiliations":[{"raw_affiliation_string":"Centro Nacional de An\u00e1lisis Gen\u00f3mico (CNAG), Barcelona, Spain","institution_ids":["https://openalex.org/I4210142206"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083128670","display_name":"Fabian Joachim Theis","orcid":"https://orcid.org/0000-0002-2419-1943","observed_orcids":["https://orcid.org/0000-0002-2419-1943"]},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Munich","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]},{"id":"https://openalex.org/I4405263983","display_name":"Institute of Computational Biology","ror":"https://ror.org/00kg2yq63","country_code":"DE","type":"education","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672","https://openalex.org/I4405263983"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Fabian J. Theis","raw_affiliation_strings":["Institute of Computational Biology, Helmholtz Munich, Neuherberg/Munich, Germany","TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany; School of Computation, Information and Technology, Technical University of Munich, Munich, Germany"],"raw_orcid":"https://orcid.org/0000-0002-2419-1943","affiliations":[{"raw_affiliation_string":"Institute of Computational Biology, Helmholtz Munich, Neuherberg/Munich, Germany","institution_ids":["https://openalex.org/I3018134672","https://openalex.org/I4405263983"]},{"raw_affiliation_string":"TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany; School of Computation, Information and Technology, Technical University of Munich, Munich, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028596003","display_name":"Sarah Amalia Teichmann","orcid":"https://orcid.org/0000-0002-6294-6366","observed_orcids":["https://orcid.org/0000-0002-6294-6366"]},"institutions":[{"id":"https://openalex.org/I109736498","display_name":"Canadian Institute for Advanced Research","ror":"https://ror.org/01sdtdd95","country_code":"CA","type":"facility","lineage":["https://openalex.org/I109736498"]},{"id":"https://openalex.org/I21196054","display_name":"Wellcome/MRC Cambridge Stem Cell Institute","ror":"https://ror.org/05nz0zp31","country_code":"GB","type":"facility","lineage":["https://openalex.org/I21196054","https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I87048295","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["CA","GB"],"is_corresponding":false,"raw_author_name":"Sarah A. Teichmann","raw_affiliation_strings":["CIFAR Macmillan Multi-scale Human Programme, CIFAR, Toronto, Canada","Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK","Department of Medicine, University of Cambridge, Cambridge, UK"],"raw_orcid":"https://orcid.org/0000-0002-6294-6366","affiliations":[{"raw_affiliation_string":"CIFAR Macmillan Multi-scale Human Programme, CIFAR, Toronto, Canada","institution_ids":["https://openalex.org/I109736498"]},{"raw_affiliation_string":"Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I21196054","https://openalex.org/I241749"]},{"raw_affiliation_string":"Department of Medicine, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053602492","display_name":"Malte D. Luecken","orcid":"https://orcid.org/0000-0001-7464-7921","observed_orcids":["https://orcid.org/0000-0001-7464-7921"]},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Munich","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]},{"id":"https://openalex.org/I4405263983","display_name":"Institute of Computational Biology","ror":"https://ror.org/00kg2yq63","country_code":"DE","type":"education","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672","https://openalex.org/I4405263983"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Malte D. Luecken","raw_affiliation_strings":["Institute of Computational Biology, Helmholtz Munich, Neuherberg/Munich, Germany","Institute of Lung Health and Immunity, Helmholtz Munich, Member of the German Center for Lung Research (DZL), Munich, Germany","TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany; School of Computation, Information and Technology, Technical University of Munich, Munich, Germany"],"raw_orcid":"https://orcid.org/0000-0001-7464-7921","affiliations":[{"raw_affiliation_string":"Institute of Computational Biology, Helmholtz Munich, Neuherberg/Munich, Germany","institution_ids":["https://openalex.org/I3018134672","https://openalex.org/I4405263983"]},{"raw_affiliation_string":"Institute of Lung Health and Immunity, Helmholtz Munich, Member of the German Center for Lung Research (DZL), Munich, Germany","institution_ids":["https://openalex.org/I3018134672","https://openalex.org/I4210129183"]},{"raw_affiliation_string":"TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany; School of Computation, Information and Technology, Technical University of Munich, Munich, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025943107","display_name":"Shyam Prabhakar","orcid":"https://orcid.org/0000-0002-6409-0661","observed_orcids":["https://orcid.org/0000-0002-6409-0661"]},"institutions":[{"id":"https://openalex.org/I4210137145","display_name":"National Cancer Centre Singapore","ror":"https://ror.org/03bqk3e80","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I4210137145"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE","SG"],"is_corresponding":false,"raw_author_name":"Shyam Prabhakar","raw_affiliation_strings":["Division of Medical Oncology-Research, National Cancer Centre Singapore, Republic of Singapore","TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany; School of Computation, Information and Technology, Technical University of Munich, Munich, Germany"],"raw_orcid":"https://orcid.org/0000-0002-6409-0661","affiliations":[{"raw_affiliation_string":"Division of Medical Oncology-Research, National Cancer Centre Singapore, Republic of Singapore","institution_ids":["https://openalex.org/I4210137145"]},{"raw_affiliation_string":"TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany; School of Computation, Information and Technology, Technical University of Munich, Munich, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047691305","display_name":"Alexandra\u2013Chlo\u00e9 Villani","orcid":"https://orcid.org/0000-0001-7461-0408","observed_orcids":["https://orcid.org/0000-0001-7461-0408"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexandra-Chlo\u00e9 Villani","raw_affiliation_strings":["Broad Institute of MIT and Harvard, Cambridge, MA, USA","Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","Harvard Medical School, Boston, MA, USA","Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0001-7461-0408","affiliations":[{"raw_affiliation_string":"Broad Institute of MIT and Harvard, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265"]},{"raw_affiliation_string":"Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039206291","display_name":"Gary Reynolds","orcid":"https://orcid.org/0000-0002-8142-8708","observed_orcids":["https://orcid.org/0000-0002-8142-8708"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Gary Reynolds","raw_affiliation_strings":["Broad Institute of MIT and Harvard, Cambridge, MA, USA","Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","Harvard Medical School, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-8142-8708","affiliations":[{"raw_affiliation_string":"Broad Institute of MIT and Harvard, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265"]},{"raw_affiliation_string":"Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":14,"institutions_distinct_count":32,"corresponding_author_ids":["https://openalex.org/A5039206291"],"corresponding_institution_ids":["https://openalex.org/I107606265","https://openalex.org/I136199984","https://openalex.org/I4210087915"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/peripheral-blood-mononuclear-cells","display_name":"peripheral blood mononuclear cells","score":0.9829999804496765},{"id":"https://openalex.org/keywords/harp","display_name":"harp","score":0.6380000114440918},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.5699999928474426},{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.9520000219345093},{"id":"https://openalex.org/keywords/prostaglandin-signaling","display_name":"prostaglandin signaling","score":0.9879999756813049},{"id":"https://openalex.org/keywords/immune-related-diseases","display_name":"immune-related diseases","score":0.7070000171661377},{"id":"https://openalex.org/keywords/data-harmonization","display_name":"data harmonization","score":0.5429999828338623}],"concepts":[{"id":"https://openalex.org/C137061746","wikidata":"https://www.wikidata.org/wiki/Q736033","display_name":"Peripheral blood mononuclear cell","level":3,"score":0.6499999761581421},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6305999755859375},{"id":"https://openalex.org/C2776673561","wikidata":"https://www.wikidata.org/wiki/Q655357","display_name":"Atlas (anatomy)","level":2,"score":0.5881999731063843},{"id":"https://openalex.org/C2776030095","wikidata":"https://www.wikidata.org/wiki/Q5628954","display_name":"HARP","level":2,"score":0.5425999760627747},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5108000040054321},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5051000118255615},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.4722000062465668},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4163999855518341},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4146000146865845},{"id":"https://openalex.org/C72634772","wikidata":"https://www.wikidata.org/wiki/Q386824","display_name":"Data integration","level":2,"score":0.3926999866962433},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.351500004529953},{"id":"https://openalex.org/C2780297707","wikidata":"https://www.wikidata.org/wiki/Q4895393","display_name":"Landmark","level":2,"score":0.34209999442100525},{"id":"https://openalex.org/C66782513","wikidata":"https://www.wikidata.org/wiki/Q864601","display_name":"Biomedicine","level":2,"score":0.32749998569488525},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3237000107765198},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.31369999051094055},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.31139999628067017},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.3059000074863434},{"id":"https://openalex.org/C58041806","wikidata":"https://www.wikidata.org/wiki/Q1660484","display_name":"Imputation (statistics)","level":3,"score":0.30480000376701355},{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.2976999878883362},{"id":"https://openalex.org/C189014844","wikidata":"https://www.wikidata.org/wiki/Q189118","display_name":"Cell type","level":3,"score":0.28049999475479126},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2777000069618225},{"id":"https://openalex.org/C7952369","wikidata":"https://www.wikidata.org/wiki/Q844116","display_name":"Phenome","level":4,"score":0.2653999924659729},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.25110000371932983},{"id":"https://openalex.org/C3020653616","wikidata":"https://www.wikidata.org/wiki/Q189146","display_name":"Cell mediated immunity","level":4,"score":0.2500999867916107}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.09.21.749940","doi":"https://doi.org/10.64898/2026.09.21.749940","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.21.749940","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/09/25/2026.09.21.749940.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.64898/2026.09.21.749940","doi":"https://doi.org/10.64898/2026.09.21.749940","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.21.749940","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/09/25/2026.09.21.749940.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.8999999761581421,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1450308333","display_name":null,"funder_award_id":"MOH-000271","funder_id":"https://openalex.org/F4320334737","funder_display_name":"National Medical Research Council"},{"id":"https://openalex.org/G6996855647","display_name":null,"funder_award_id":"CZF2019-002446","funder_id":"https://openalex.org/F4320326621","funder_display_name":"National Healthcare Group"},{"id":"https://openalex.org/G8682988034","display_name":null,"funder_award_id":"MOH-000271-00","funder_id":"https://openalex.org/F4320334737","funder_display_name":"National Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320306192","display_name":"Silicon Valley Community Foundation","ror":"https://ror.org/001ader08"},{"id":"https://openalex.org/F4320308971","display_name":"Rheumatology Research Foundation","ror":"https://ror.org/03sdr0263"},{"id":"https://openalex.org/F4320320283","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10"},{"id":"https://openalex.org/F4320320766","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302"},{"id":"https://openalex.org/F4320326621","display_name":"National Healthcare Group","ror":"https://ror.org/05qkemg93"},{"id":"https://openalex.org/F4320334737","display_name":"National Medical Research Council","ror":"https://ror.org/04x3cxs03"},{"id":"https://openalex.org/F4320335736","display_name":"Lee Kong Chian School of Medicine, Nanyang Technological University","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7214298271.pdf","grobid_xml":"https://content.openalex.org/works/W7214298271.grobid-xml"},"referenced_works_count":86,"referenced_works":["https://openalex.org/W1556334181","https://openalex.org/W1859228485","https://openalex.org/W1965827638","https://openalex.org/W2052204012","https://openalex.org/W2052611179","https://openalex.org/W2107018762","https://openalex.org/W2108488321","https://openalex.org/W2114104545","https://openalex.org/W2129935236","https://openalex.org/W2146512944","https://openalex.org/W2166893697","https://openalex.org/W2313856416","https://openalex.org/W2332292689","https://openalex.org/W2560265676","https://openalex.org/W2602848567","https://openalex.org/W2605810679","https://openalex.org/W2766959028","https://openalex.org/W2774486220","https://openalex.org/W2800392236","https://openalex.org/W2801527818","https://openalex.org/W2901765988","https://openalex.org/W2905317377","https://openalex.org/W2917547201","https://openalex.org/W2948104182","https://openalex.org/W2954542358","https://openalex.org/W2967918238","https://openalex.org/W2980639756","https://openalex.org/W2983248500","https://openalex.org/W2984472267","https://openalex.org/W2995410603","https://openalex.org/W3006033724","https://openalex.org/W3013543068","https://openalex.org/W3013824109","https://openalex.org/W3032533580","https://openalex.org/W3037544553","https://openalex.org/W3041278562","https://openalex.org/W3044388039","https://openalex.org/W3046454618","https://openalex.org/W3047402958","https://openalex.org/W3099316564","https://openalex.org/W3104041940","https://openalex.org/W3121168830","https://openalex.org/W3126460810","https://openalex.org/W3153732845","https://openalex.org/W3164692211","https://openalex.org/W3170939617","https://openalex.org/W3195806951","https://openalex.org/W3196650609","https://openalex.org/W4200289086","https://openalex.org/W4223893712","https://openalex.org/W4223992851","https://openalex.org/W4225598893","https://openalex.org/W4285396235","https://openalex.org/W4296167903","https://openalex.org/W4307780828","https://openalex.org/W4311814266","https://openalex.org/W4312201951","https://openalex.org/W4362466820","https://openalex.org/W4387392783","https://openalex.org/W4387451658","https://openalex.org/W4388628847","https://openalex.org/W4390064086","https://openalex.org/W4390984725","https://openalex.org/W4392004500","https://openalex.org/W4392168151","https://openalex.org/W4399387478","https://openalex.org/W4399914260","https://openalex.org/W4402223675","https://openalex.org/W4402620302","https://openalex.org/W4404566628","https://openalex.org/W4404566941","https://openalex.org/W4404793799","https://openalex.org/W4404860402","https://openalex.org/W4405375104","https://openalex.org/W4406366498","https://openalex.org/W4408413441","https://openalex.org/W4408613341","https://openalex.org/W4411111057","https://openalex.org/W4412759856","https://openalex.org/W4414398462","https://openalex.org/W4415101863","https://openalex.org/W4416446407","https://openalex.org/W4416499443","https://openalex.org/W6912896072","https://openalex.org/W7129006512","https://openalex.org/W7140645910"],"related_works":["https://openalex.org/W4416625093","https://openalex.org/W4313368869","https://openalex.org/W7171553964","https://openalex.org/W4409016263","https://openalex.org/W4400022059","https://openalex.org/W4387451658","https://openalex.org/W7171782490","https://openalex.org/W4383315162","https://openalex.org/W3132570311","https://openalex.org/W4416380854"],"abstract_inverted_index":{"Abstract":[0],"Blood":[1],"provides":[2,175],"an":[3,49],"accessible":[4],"window":[5],"into":[6],"human":[7],"health,":[8],"yet":[9],"the":[10],"absence":[11],"of":[12,52,109,193],"a":[13,136,147,164,176,187],"peripheral":[14],"blood":[15],"mononuclear":[16],"cells":[17],"(PBMCs)":[18],"reference":[19,168,179],"with":[20,117],"standardized":[21],"immune":[22,98],"cell":[23,99,156],"annotations":[24,95,157],"has":[25],"constrained":[26],"comparisons":[27],"between":[28],"single-cell":[29,194],"RNA":[30],"sequencing":[31],"(scRNAseq)":[32],"studies.":[33,173],"Here,":[34],"we":[35,144],"present":[36],"HARP":[37,111,174],"(":[38],"H":[39],"uman":[40],"Cell":[41],"A":[42],"tlas":[43],"R":[44],"eference":[45],"for":[46,96,169,181,189],"P":[47],"BMCs),":[48],"integrated":[50],"atlas":[51,180],"\u223c9":[53],"million":[54,160],"PBMCs":[55],"from":[56],">2,600":[57],"donors":[58],"across":[59,72],"15":[60],"studies":[61],"spanning":[62],"four":[63],"continents,":[64],"encompassing":[65],"diverse":[66,75],"populations,":[67],"neonates":[68],"to":[69,87],"97":[70],"years,":[71],"health":[73],"and":[74,91,120,125,129,134,166,184],"immune-related":[76],"diseases.":[77],"We":[78],"developed":[79],"optimized":[80],"integration":[81,89],"workflows,":[82],"including":[83],"novel":[84,137],"label-free":[85],"metrics":[86],"assess":[88],"quality,":[90],"generated":[92],"community-driven":[93,178],"consensus":[94],"192":[97,155],"subsets,":[100],"identifying":[101],"rare":[102],"populations":[103],"representing":[104],"as":[105,107,186],"few":[106],"0.004%":[108],"PBMCs.":[110],"reveals":[112],"coordinated":[113],"cellular":[114],"modules":[115],"associated":[116],"age,":[118],"sex,":[119],"disease,":[121],"identifies":[122],"female-biased":[123],"interferon":[124],"inflammatory":[126],"gene":[127],"programs":[128],"their":[130],"perturbation":[131],"by":[132],"COVID-19,":[133],"uncovers":[135],"sexual":[138],"dimorphism":[139],"in":[140],"prostaglandin":[141],"signaling.":[142],"Finally,":[143],"introduce":[145],"scTiger,":[146],"hierarchical":[148],"label-transfer":[149],"framework":[150],"that":[151],"accurately":[152],"projects":[153],"these":[154],"onto":[158],"\u223c18":[159],"additional":[161],"PBMCs,":[162],"providing":[163],"robust":[165],"transferable":[167],"harmonizing":[170],"future":[171],"PBMC":[172,182],"high-resolution":[177],"annotation":[183],"analysis,":[185],"basis":[188],"emerging":[190],"clinical":[191],"applications":[192],"genomics.":[195]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-09-26T00:00:00"}
