{"id":"https://openalex.org/W7214101551","doi":"https://doi.org/10.1002/alz.71840","title":"Kidney function and brain health: cognitive and structural signatures across cohorts","display_name":"Kidney function and brain health: cognitive and structural signatures across cohorts","publication_year":2026,"publication_date":"2026-09-01","ids":{"openalex":"https://openalex.org/W7214101551","doi":"https://doi.org/10.1002/alz.71840","pmid":"https://pubmed.ncbi.nlm.nih.gov/42773880","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13598550"},"language":"en","primary_location":{"id":"doi:10.1002/alz.71840","doi":"https://doi.org/10.1002/alz.71840","is_oa":true,"landing_page_url":"https://doi.org/10.1002/alz.71840","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/alz.71840","source":{"id":"https://openalex.org/S108427512","display_name":"Alzheimer s & Dementia","issn_l":"1552-5260","issn":["1552-5260","1552-5279"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-3","ki-jl-3","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimer's & Dementia","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/alz.71840","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5153008168","display_name":"Min Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210147433","display_name":"Beijing Friendship Hospital","ror":"https://ror.org/053qy4437","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Min Li","raw_affiliation_strings":["Clinical Epidemiology and EBM Unit Beijing Friendship Hospital Capital Medical University  Beijing China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Epidemiology and EBM Unit Beijing Friendship Hospital Capital Medical University  Beijing China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210147433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5139586372","display_name":"Wenbo Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210147433","display_name":"Beijing Friendship Hospital","ror":"https://ror.org/053qy4437","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenbo Yang","raw_affiliation_strings":["Department of Radiology Beijing Friendship Hospital Capital Medical University  Beijing China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology Beijing Friendship Hospital Capital Medical University  Beijing China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210147433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100906814","display_name":"Hui Ying","orcid":"https://orcid.org/0000-0001-9124-9941","observed_orcids":["https://orcid.org/0000-0001-9124-9941"]},"institutions":[{"id":"https://openalex.org/I4210109698","display_name":"Kailuan General Hospital","ror":"https://ror.org/01kwdp645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210109698"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Hui","raw_affiliation_strings":["Department of Radiology Kailuan General Hospital  Tangshan Hebei China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology Kailuan General Hospital  Tangshan Hebei China","institution_ids":["https://openalex.org/I4210109698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122946183","display_name":"Huijing Shi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210109698","display_name":"Kailuan General Hospital","ror":"https://ror.org/01kwdp645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210109698"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huijing Shi","raw_affiliation_strings":["Department of Radiology Kailuan General Hospital  Tangshan Hebei China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology Kailuan General Hospital  Tangshan Hebei China","institution_ids":["https://openalex.org/I4210109698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5152559816","display_name":"Yuntao Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210109698","display_name":"Kailuan General Hospital","ror":"https://ror.org/01kwdp645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210109698"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuntao Wu","raw_affiliation_strings":["Department of Radiology Kailuan General Hospital  Tangshan Hebei China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology Kailuan General Hospital  Tangshan Hebei China","institution_ids":["https://openalex.org/I4210109698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5139628103","display_name":"Li Yu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210147433","display_name":"Beijing Friendship Hospital","ror":"https://ror.org/053qy4437","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li Yu","raw_affiliation_strings":["Department of Radiology Beijing Friendship Hospital Capital Medical University  Beijing China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology Beijing Friendship Hospital Capital Medical University  Beijing China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210147433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100944944","display_name":"Lijun Song","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210147433","display_name":"Beijing Friendship Hospital","ror":"https://ror.org/053qy4437","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lijun Song","raw_affiliation_strings":["Department of Radiology Beijing Friendship Hospital Capital Medical University  Beijing China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology Beijing Friendship Hospital Capital Medical University  Beijing China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210147433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5152556531","display_name":"Yanfang Tan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210147433","display_name":"Beijing Friendship Hospital","ror":"https://ror.org/053qy4437","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanfang Tan","raw_affiliation_strings":["Clinical Epidemiology and EBM Unit Beijing Friendship Hospital Capital Medical University  Beijing China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Epidemiology and EBM Unit Beijing Friendship Hospital Capital Medical University  Beijing China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210147433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5146548552","display_name":"Xintian Ren","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210147433","display_name":"Beijing Friendship Hospital","ror":"https://ror.org/053qy4437","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xintian Ren","raw_affiliation_strings":["Clinical Epidemiology and EBM Unit Beijing Friendship Hospital Capital Medical University  Beijing China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Epidemiology and EBM Unit Beijing Friendship Hospital Capital Medical University  Beijing China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210147433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122884060","display_name":"Xiaoyan Bai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210147433","display_name":"Beijing Friendship Hospital","ror":"https://ror.org/053qy4437","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoyan Bai","raw_affiliation_strings":["Department of Radiology Beijing Friendship Hospital Capital Medical University  Beijing China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology Beijing Friendship Hospital Capital Medical University  Beijing China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210147433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101455455","display_name":"Xiaoshuai Li","orcid":"https://orcid.org/0000-0002-2913-9343","observed_orcids":["https://orcid.org/0000-0002-2913-9343","https://orcid.org/0000-0001-5592-0697"]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210147433","display_name":"Beijing Friendship Hospital","ror":"https://ror.org/053qy4437","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoshuai Li","raw_affiliation_strings":["Department of Radiology Beijing Friendship Hospital Capital Medical University  Beijing China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology Beijing Friendship Hospital Capital Medical University  Beijing China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210147433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045874160","display_name":"Zhenghan Yang","orcid":"https://orcid.org/0000-0003-3986-1732","observed_orcids":["https://orcid.org/0000-0003-3986-1732"]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210147433","display_name":"Beijing Friendship Hospital","ror":"https://ror.org/053qy4437","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhenghan Yang","raw_affiliation_strings":["Department of Radiology Beijing Friendship Hospital Capital Medical University  Beijing China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology Beijing Friendship Hospital Capital Medical University  Beijing China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210147433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101154942","display_name":"Weikang Guo","orcid":"https://orcid.org/0000-0002-5411-2337","observed_orcids":["https://orcid.org/0000-0002-5411-2337"]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210147433","display_name":"Beijing Friendship Hospital","ror":"https://ror.org/053qy4437","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weikang Guo","raw_affiliation_strings":["Department of Nephrology Beijing Friendship Hospital Capital Medical University  Beijing China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology Beijing Friendship Hospital Capital Medical University  Beijing China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210147433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5136498287","display_name":"Shouling Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210109698","display_name":"Kailuan General Hospital","ror":"https://ror.org/01kwdp645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210109698"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shouling Wu","raw_affiliation_strings":["Department of Cardiology Kailuan General Hospital  Tangshan Hebei China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology Kailuan General Hospital  Tangshan Hebei China","institution_ids":["https://openalex.org/I4210109698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122975993","display_name":"Jing Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210153550","display_name":"Beijing Tsinghua Chang Gung Hospital","ror":"https://ror.org/050nfgr37","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153550"]},{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Li","raw_affiliation_strings":["Department of Radiology School of Clinical Medicine Beijing Tsinghua Changgung Hospital Tsinghua University  Beijing China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology School of Clinical Medicine Beijing Tsinghua Changgung Hospital Tsinghua University  Beijing China","institution_ids":["https://openalex.org/I4210153550","https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5134461125","display_name":"Zhenchang Wang","orcid":"https://orcid.org/0000-0001-8190-6469","observed_orcids":["https://orcid.org/0000-0001-8190-6469"]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210147433","display_name":"Beijing Friendship Hospital","ror":"https://ror.org/053qy4437","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147433"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhenchang Wang","raw_affiliation_strings":["Beijing Key Laboratory of Innovation and Transformation of Specialized CT/MR Imaging Equipment  Beijing China","Department of Radiology Beijing Friendship Hospital Capital Medical University  Beijing China","Precision and Intelligence Medical Imaging Lab Beijing Friendship Hospital Capital Medical University  Beijing China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory of Innovation and Transformation of Specialized CT/MR Imaging Equipment  Beijing China","institution_ids":[]},{"raw_affiliation_string":"Department of Radiology Beijing Friendship Hospital Capital Medical University  Beijing China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210147433"]},{"raw_affiliation_string":"Precision and Intelligence Medical Imaging Lab Beijing Friendship Hospital Capital Medical University  Beijing China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210147433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024638516","display_name":"Han Lv","orcid":"https://orcid.org/0000-0001-9559-4777","observed_orcids":["https://orcid.org/0000-0001-9559-4777"]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210147433","display_name":"Beijing Friendship Hospital","ror":"https://ror.org/053qy4437","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147433"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Han Lv","raw_affiliation_strings":["Beijing Key Laboratory of Innovation and Transformation of Specialized CT/MR Imaging Equipment  Beijing China","Department of Radiology Beijing Friendship Hospital Capital Medical University  Beijing China","Precision and Intelligence Medical Imaging Lab Beijing Friendship Hospital Capital Medical University  Beijing China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory of Innovation and Transformation of Specialized CT/MR Imaging Equipment  Beijing China","institution_ids":[]},{"raw_affiliation_string":"Department of Radiology Beijing Friendship Hospital Capital Medical University  Beijing China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210147433"]},{"raw_affiliation_string":"Precision and Intelligence Medical Imaging Lab Beijing Friendship Hospital Capital Medical University  Beijing China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210147433"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100625423","display_name":"Hao Wang","orcid":"https://orcid.org/0000-0002-6884-6323","observed_orcids":["https://orcid.org/0000-0002-6884-6323","https://orcid.org/0009-0001-9542-7212"]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210147433","display_name":"Beijing Friendship Hospital","ror":"https://ror.org/053qy4437","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147433"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hao Wang","raw_affiliation_strings":["Beijing Key Laboratory of Innovation and Transformation of Specialized CT/MR Imaging Equipment  Beijing China","Department of Radiology Beijing Friendship Hospital Capital Medical University  Beijing China","Precision and Intelligence Medical Imaging Lab Beijing Friendship Hospital Capital Medical University  Beijing China"],"raw_orcid":"https://orcid.org/0000-0002-6884-6323","affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory of Innovation and Transformation of Specialized CT/MR Imaging Equipment  Beijing China","institution_ids":[]},{"raw_affiliation_string":"Department of Radiology Beijing Friendship Hospital Capital Medical University  Beijing China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210147433"]},{"raw_affiliation_string":"Precision and Intelligence Medical Imaging Lab Beijing Friendship Hospital Capital Medical University  Beijing China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210147433"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5024638516","https://openalex.org/A5100625423","https://openalex.org/A5134461125"],"corresponding_institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210147433"],"apc_list":{"value":4200,"currency":"USD","value_usd":4200},"apc_paid":{"value":4200,"currency":"USD","value_usd":4200},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.69719413,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"22","issue":"9","first_page":"e71840","last_page":"e71840"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.011599999852478504,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13077","display_name":"Cancer-related cognitive impairment studies","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.9990000128746033},{"id":"https://openalex.org/keywords/estimated-glomerular-filtration-rate","display_name":"estimated glomerular filtration rate","score":0.9660000205039978}],"concepts":[{"id":"https://openalex.org/C2776632958","wikidata":"https://www.wikidata.org/wiki/Q6906262","display_name":"Montreal Cognitive Assessment","level":4,"score":0.7835999727249146},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7134000062942505},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.671500027179718},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.5134999752044678},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.48429998755455017},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.47679999470710754},{"id":"https://openalex.org/C2779632907","wikidata":"https://www.wikidata.org/wiki/Q13444883","display_name":"Brain Structure and Function","level":3,"score":0.44519999623298645},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.42739999294281006},{"id":"https://openalex.org/C2778402161","wikidata":"https://www.wikidata.org/wiki/Q2121931","display_name":"Anterior cingulate cortex","level":3,"score":0.4153999984264374},{"id":"https://openalex.org/C2984863031","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Cognitive decline","level":4,"score":0.4081000089645386},{"id":"https://openalex.org/C146638467","wikidata":"https://www.wikidata.org/wiki/Q10529587","display_name":"Hyperintensity","level":3,"score":0.40070000290870667},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.3986000120639801},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.3343000113964081},{"id":"https://openalex.org/C2781210436","wikidata":"https://www.wikidata.org/wiki/Q1892702","display_name":"Cingulate cortex","level":3,"score":0.31709998846054077},{"id":"https://openalex.org/C185711340","wikidata":"https://www.wikidata.org/wiki/Q5347381","display_name":"Effects of sleep deprivation on cognitive performance","level":3,"score":0.3167000114917755},{"id":"https://openalex.org/C2777348757","wikidata":"https://www.wikidata.org/wiki/Q2346577","display_name":"Cortex (anatomy)","level":2,"score":0.30959999561309814},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.3052999973297119},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.30239999294281006},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.29100000858306885},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.29010000824928284},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.28679999709129333},{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.2867000102996826},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.28220000863075256},{"id":"https://openalex.org/C142052008","wikidata":"https://www.wikidata.org/wiki/Q954027","display_name":"Cross-sectional study","level":2,"score":0.2660999894142151},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.2655999958515167},{"id":"https://openalex.org/C50231774","wikidata":"https://www.wikidata.org/wiki/Q639842","display_name":"Brain mapping","level":2,"score":0.2653999924659729},{"id":"https://openalex.org/C2779226451","wikidata":"https://www.wikidata.org/wiki/Q903809","display_name":"Functional magnetic resonance imaging","level":2,"score":0.2624000012874603},{"id":"https://openalex.org/C2778733324","wikidata":"https://www.wikidata.org/wiki/Q2998088","display_name":"Posterior cingulate","level":3,"score":0.25760000944137573},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.2572000026702881},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.2522999942302704},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.2513999938964844}],"mesh":[{"descriptor_ui":"D000073216","descriptor_name":"Mental Status and Dementia Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000097849","descriptor_name":"UK Biobank","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005919","descriptor_name":"Glomerular Filtration Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1002/alz.71840","doi":"https://doi.org/10.1002/alz.71840","is_oa":true,"landing_page_url":"https://doi.org/10.1002/alz.71840","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/alz.71840","source":{"id":"https://openalex.org/S108427512","display_name":"Alzheimer s & Dementia","issn_l":"1552-5260","issn":["1552-5260","1552-5279"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-3","ki-jl-3","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimer's & Dementia","raw_type":"journal-article"},{"id":"pmid:42773880","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42773880","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimer's & dementia : the journal of the Alzheimer's Association","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13598550","doi":null,"is_oa":true,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42773880/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimers Dement","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1002/alz.71840","doi":"https://doi.org/10.1002/alz.71840","is_oa":true,"landing_page_url":"https://doi.org/10.1002/alz.71840","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/alz.71840","source":{"id":"https://openalex.org/S108427512","display_name":"Alzheimer s & Dementia","issn_l":"1552-5260","issn":["1552-5260","1552-5279"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-3","ki-jl-3","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimer's & Dementia","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G4477775406","display_name":null,"funder_award_id":"52227814","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5587401098","display_name":null,"funder_award_id":"yyqcjh2023\u20107","funder_id":"https://openalex.org/F4320336795","funder_display_name":"Beijing Friendship Hospital, Capital Medical University"},{"id":"https://openalex.org/G9000382886","display_name":null,"funder_award_id":"82572190","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321496","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60"},{"id":"https://openalex.org/F4320336795","display_name":"Beijing Friendship Hospital, Capital Medical University","ror":"https://ror.org/053qy4437"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7214101551.pdf","grobid_xml":"https://content.openalex.org/works/W7214101551.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W2019587683","https://openalex.org/W2041570990","https://openalex.org/W2043356371","https://openalex.org/W2067240723","https://openalex.org/W2082704080","https://openalex.org/W2093935755","https://openalex.org/W2112891119","https://openalex.org/W2114046308","https://openalex.org/W2129130648","https://openalex.org/W2165758561","https://openalex.org/W2405961113","https://openalex.org/W2607804943","https://openalex.org/W2965654579","https://openalex.org/W3015186969","https://openalex.org/W3046275966","https://openalex.org/W3092583017","https://openalex.org/W3095099370","https://openalex.org/W3110978274","https://openalex.org/W3111785559","https://openalex.org/W3158718778","https://openalex.org/W3195973239","https://openalex.org/W3201595862","https://openalex.org/W4206055706","https://openalex.org/W4319956361","https://openalex.org/W4380369505","https://openalex.org/W4385827917","https://openalex.org/W4385988550","https://openalex.org/W4392777592","https://openalex.org/W4404763084","https://openalex.org/W4405122908","https://openalex.org/W4408211661","https://openalex.org/W4409781757","https://openalex.org/W4413257103","https://openalex.org/W4414424372","https://openalex.org/W7129438909","https://openalex.org/W7134049766","https://openalex.org/W7137831306"],"related_works":["https://openalex.org/W4404763084","https://openalex.org/W4397042305","https://openalex.org/W2980323987","https://openalex.org/W2532193479","https://openalex.org/W2152567814","https://openalex.org/W4297370161","https://openalex.org/W4307958530","https://openalex.org/W2592382104","https://openalex.org/W4249942452","https://openalex.org/W4365444304"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Chronic":[1],"kidney":[2],"disease":[3],"(CKD)":[4],"is":[5],"linked":[6],"to":[7,98,116],"cognitive":[8],"decline,":[9],"yet":[10],"the":[11,65],"roles":[12],"of":[13],"estimated":[14],"glomerular":[15],"filtration":[16],"rate":[17],"(eGFR)":[18],"and":[19,45,58,70,129,144,148,158,168],"its":[20],"variability":[21,103,136,161],"remain":[22],"unclear.":[23],"METHODS:":[24],"We":[25],"analyzed":[26],"6847":[27],"adults":[28],"from":[29,49],"two":[30],"population-based":[31],"cohorts":[32],"(the":[33],"Multimodality":[34],"MEdical":[35],"imaging":[36,76],"sTudy":[37],"bAsed":[38],"on":[39],"KaiLuan":[40],"Study":[41],"[META-KLS],":[42],"UK":[43],"Biobank)":[44],"426":[46],"CKD":[47],"patients":[48],"Beijing":[50],"Friendship":[51],"Hospital":[52],"(BFH)-CKD.":[53],"Exposures":[54],"included":[55],"eGFR":[56,83,102,121,157,160],"level":[57],"variability.":[59],"Cognitive":[60,67],"function":[61],"was":[62,84,104,122],"assessed":[63],"using":[64],"Montreal":[66],"Assessment":[68],"(MoCA)":[69],"brain":[71,171],"structure":[72],"by":[73],"magnetic":[74],"resonance":[75],"(MRI).":[77],"RESULTS:":[78],"In":[79,133],"META-KLS,":[80,134],"higher":[81,87,120],"cumulative":[82],"associated":[85,105,123,163],"with":[86,106,124,141,164],"MoCA":[88,108,166],"scores":[89,109,167],"(\u03b2":[90,110],"=":[91,111],"0.350;":[92],"95%":[93,113],"confidence":[94],"interval":[95],"[CI]:":[96],"0.148":[97],"0.552),":[99],"whereas":[100],"greater":[101,135,159],"lower":[107,165],"-0.454;":[112],"CI:":[114],"-0.659":[115],"-0.250).":[117],"Across":[118],"cohorts,":[119],"white":[125],"matter,":[126],"superior":[127],"frontal,":[128],"middle":[130,145],"temporal":[131,146],"volumes.":[132],"showed":[137],"nominal":[138],"inverse":[139],"associations":[140],"inferior":[142],"parietal":[143],"volumes":[147],"reduced":[149],"rostral":[150],"anterior":[151],"cingulate":[152],"cortex":[153],"thickness.":[154],"DISCUSSION:":[155],"Lower":[156],"were":[162],"region-specific":[169],"structural":[170],"alterations.":[172]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2026-09-24T00:00:00"}