{"id":"https://openalex.org/W7214092397","doi":"https://doi.org/10.3390/antiox15101226","title":"Nanoencapsulation Transforms Curcumin\u2019s Antiparasitic Activity: Reduced Dose and Altered Mechanism in Taenia crassiceps Cysticerci","display_name":"Nanoencapsulation Transforms Curcumin\u2019s Antiparasitic Activity: Reduced Dose and Altered Mechanism in Taenia crassiceps Cysticerci","publication_year":2026,"publication_date":"2026-09-23","ids":{"openalex":"https://openalex.org/W7214092397","doi":"https://doi.org/10.3390/antiox15101226","pmid":"https://pubmed.ncbi.nlm.nih.gov/42939800","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13700812"},"language":"en","primary_location":{"id":"doi:10.3390/antiox15101226","doi":"https://doi.org/10.3390/antiox15101226","is_oa":true,"landing_page_url":"https://doi.org/10.3390/antiox15101226","pdf_url":null,"source":{"id":"https://openalex.org/S2737566431","display_name":"Antioxidants","issn_l":"2076-3921","issn":["2076-3921"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/antiox15101226","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013800465","display_name":"Jos\u00e9 de Jes\u00fas Mart\u00ednez-Gonz\u00e1lez","orcid":"https://orcid.org/0000-0002-4240-739X","observed_orcids":["https://orcid.org/0000-0002-4240-739X"]},"institutions":[{"id":"https://openalex.org/I8961855","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25","country_code":"MX","type":"education","lineage":["https://openalex.org/I8961855"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 de Jes\u00fas Mart\u00ednez-Gonz\u00e1lez","raw_affiliation_strings":["Departamento de Bioqu\u00edmica, Facultad de Medicina, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Mexico City 04510, Mexico"],"raw_orcid":"https://orcid.org/0000-0002-4240-739X","affiliations":[{"raw_affiliation_string":"Departamento de Bioqu\u00edmica, Facultad de Medicina, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Mexico City 04510, Mexico","institution_ids":["https://openalex.org/I8961855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5152536881","display_name":"Lucero Reyes-Garc\u00eda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8961855","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25","country_code":"MX","type":"education","lineage":["https://openalex.org/I8961855"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Lucero Reyes-Garc\u00eda","raw_affiliation_strings":["Departamento de Bioqu\u00edmica, Facultad de Medicina, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Mexico City 04510, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bioqu\u00edmica, Facultad de Medicina, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Mexico City 04510, Mexico","institution_ids":["https://openalex.org/I8961855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017915796","display_name":"Alberto Guevara\u2010Flores","orcid":"https://orcid.org/0000-0003-4429-770X","observed_orcids":["https://orcid.org/0000-0003-4429-770X"]},"institutions":[{"id":"https://openalex.org/I8961855","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25","country_code":"MX","type":"education","lineage":["https://openalex.org/I8961855"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Alberto Guevara-Flores","raw_affiliation_strings":["Departamento de Bioqu\u00edmica, Facultad de Medicina, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Mexico City 04510, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bioqu\u00edmica, Facultad de Medicina, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Mexico City 04510, Mexico","institution_ids":["https://openalex.org/I8961855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068939700","display_name":"Mart\u00edn Escamilla-Del-Arenal","orcid":"https://orcid.org/0009-0008-6218-1210","observed_orcids":["https://orcid.org/0009-0008-6218-1210"]},"institutions":[{"id":"https://openalex.org/I4405270606","display_name":"Mortimer B. Zuckerman Mind Brain Behavior Institute","ror":"https://ror.org/0110mmp98","country_code":"US","type":"facility","lineage":["https://openalex.org/I4405270606"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mart\u00edn Escamilla-del-Arenal","raw_affiliation_strings":["Department of Biochemistry and Molecular Biophysics, Mortimer B. Zuckerman Mind, Brain, and Behavior Institute, Columbia University, Jerome L. Greene Science Center, 3227 Broadway, New York, NY 10027, USA"],"raw_orcid":"https://orcid.org/0009-0008-6218-1210","affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biophysics, Mortimer B. Zuckerman Mind, Brain, and Behavior Institute, Columbia University, Jerome L. Greene Science Center, 3227 Broadway, New York, NY 10027, USA","institution_ids":["https://openalex.org/I4405270606","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023151485","display_name":"Rachel Duffi\u00e9","orcid":"https://orcid.org/0000-0001-8529-1377","observed_orcids":["https://orcid.org/0000-0001-8529-1377"]},"institutions":[{"id":"https://openalex.org/I8961855","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25","country_code":"MX","type":"education","lineage":["https://openalex.org/I8961855"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Rachel Austin Duffi\u00e9","raw_affiliation_strings":["Instituto de Ecolog\u00eda, Universidad Nacional Aut\u00f3noma de M\u00e9xico, 04510 (UNAM), Mexico City 04510, Mexico"],"raw_orcid":"https://orcid.org/0000-0001-8529-1377","affiliations":[{"raw_affiliation_string":"Instituto de Ecolog\u00eda, Universidad Nacional Aut\u00f3noma de M\u00e9xico, 04510 (UNAM), Mexico City 04510, Mexico","institution_ids":["https://openalex.org/I8961855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5095764218","display_name":"Gabriela Nava-Balderas","orcid":"https://orcid.org/0009-0005-6960-7497","observed_orcids":["https://orcid.org/0009-0005-6960-7497"]},"institutions":[{"id":"https://openalex.org/I8961855","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25","country_code":"MX","type":"education","lineage":["https://openalex.org/I8961855"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Gabriela Nava-Balderas","raw_affiliation_strings":["Departamento de Microbiolog\u00eda y Parasitolog\u00eda, Facultad de Medicina, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Mexico City 04510, Mexico"],"raw_orcid":"https://orcid.org/0009-0005-6960-7497","affiliations":[{"raw_affiliation_string":"Departamento de Microbiolog\u00eda y Parasitolog\u00eda, Facultad de Medicina, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Mexico City 04510, Mexico","institution_ids":["https://openalex.org/I8961855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041224036","display_name":"Gerardo Leyva\u2010G\u00f3mez","orcid":"https://orcid.org/0000-0002-7940-1100","observed_orcids":["https://orcid.org/0000-0002-7940-1100"]},"institutions":[{"id":"https://openalex.org/I8961855","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25","country_code":"MX","type":"education","lineage":["https://openalex.org/I8961855"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Gerardo Leyva-G\u00f3mez","raw_affiliation_strings":["Departamento de Farmacia, Facultad de Qu\u00edmica, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Mexico City 04510, Mexico"],"raw_orcid":"https://orcid.org/0000-0002-7940-1100","affiliations":[{"raw_affiliation_string":"Departamento de Farmacia, Facultad de Qu\u00edmica, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Mexico City 04510, Mexico","institution_ids":["https://openalex.org/I8961855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064888752","display_name":"Mar\u00ed\u00ada Luisa Del Prado-Audelo","orcid":"https://orcid.org/0000-0003-4238-2724","observed_orcids":["https://orcid.org/0000-0003-4238-2724"]},"institutions":[{"id":"https://openalex.org/I98461037","display_name":"Tecnol\u00f3gico de Monterrey","ror":"https://ror.org/03ayjn504","country_code":"MX","type":"education","lineage":["https://openalex.org/I98461037"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Mar\u00eda Luisa Del Prado-Audelo","raw_affiliation_strings":["Escuela de Ingenieria y Ciencias, Tecnol\u00f3gico de Monterrey Campus Ciudad de Mexico, C. Puente 222, Mexico City 14380, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Escuela de Ingenieria y Ciencias, Tecnol\u00f3gico de Monterrey Campus Ciudad de Mexico, C. Puente 222, Mexico City 14380, Mexico","institution_ids":["https://openalex.org/I98461037"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023567905","display_name":"Irene Patricia del Arenal Mena","orcid":"https://orcid.org/0000-0001-8174-9985","observed_orcids":["https://orcid.org/0000-0001-8174-9985"]},"institutions":[{"id":"https://openalex.org/I8961855","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25","country_code":"MX","type":"education","lineage":["https://openalex.org/I8961855"]}],"countries":["MX"],"is_corresponding":true,"raw_author_name":"Irene Patricia del Arenal Mena","raw_affiliation_strings":["Departamento de Bioqu\u00edmica, Facultad de Medicina, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Mexico City 04510, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bioqu\u00edmica, Facultad de Medicina, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Mexico City 04510, Mexico","institution_ids":["https://openalex.org/I8961855"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5023567905"],"corresponding_institution_ids":["https://openalex.org/I8961855"],"apc_list":{"value":2900,"currency":"CHF","value_usd":3499},"apc_paid":{"value":2900,"currency":"CHF","value_usd":3499},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.68572993,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"15","issue":"10","first_page":"1226","last_page":"1226"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11154","display_name":"Parasitic infections in humans and animals","score":0.7207000255584717,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11154","display_name":"Parasitic infections in humans and animals","score":0.7207000255584717,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11319","display_name":"Curcumin's Biomedical Applications","score":0.17219999432563782,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11074","display_name":"Helminth infection and control","score":0.04729999974370003,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/curcumin","display_name":"curcumin","score":0.996999979019165},{"id":"https://openalex.org/keywords/nanoencapsulation","display_name":"nanoencapsulation","score":0.8560000061988831},{"id":"https://openalex.org/keywords/taenia-crassiceps","display_name":"Taenia crassiceps","score":0.8149999976158142},{"id":"https://openalex.org/keywords/cysticerci","display_name":"cysticerci","score":0.859000027179718},{"id":"https://openalex.org/keywords/cysticercosis","display_name":"cysticercosis","score":0.9110000133514404},{"id":"https://openalex.org/keywords/anthelmintic-activity","display_name":"anthelmintic activity","score":0.8190000057220459},{"id":"https://openalex.org/keywords/polycaprolactone-nanoparticles","display_name":"polycaprolactone nanoparticles","score":0.902999997138977},{"id":"https://openalex.org/keywords/poloxamer-188","display_name":"poloxamer 188","score":0.9950000047683716},{"id":"https://openalex.org/keywords/redox-metabolism","display_name":"redox metabolism","score":0.7269999980926514},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.800000011920929},{"id":"https://openalex.org/keywords/tegumental-damage","display_name":"tegumental damage","score":0.8640000224113464},{"id":"https://openalex.org/keywords/drug-stability","display_name":"drug stability","score":0.5669999718666077},{"id":"https://openalex.org/keywords/bioavailability","display_name":"bioavailability","score":0.9330000281333923}],"concepts":[{"id":"https://openalex.org/C2775963980","wikidata":"https://www.wikidata.org/wiki/Q287611","display_name":"Taenia crassiceps","level":4,"score":0.939300000667572},{"id":"https://openalex.org/C2778250585","wikidata":"https://www.wikidata.org/wiki/Q312266","display_name":"Curcumin","level":2,"score":0.8447999954223633},{"id":"https://openalex.org/C181389837","wikidata":"https://www.wikidata.org/wiki/Q461809","display_name":"Bioavailability","level":2,"score":0.8310999870300293},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.7235000133514404},{"id":"https://openalex.org/C2781421772","wikidata":"https://www.wikidata.org/wiki/Q581102","display_name":"Antiparasitic","level":2,"score":0.6437000036239624},{"id":"https://openalex.org/C2776908094","wikidata":"https://www.wikidata.org/wiki/Q572294","display_name":"Anthelmintic","level":2,"score":0.6158999800682068},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5598999857902527},{"id":"https://openalex.org/C2779744950","wikidata":"https://www.wikidata.org/wiki/Q424145","display_name":"Praziquantel","level":4,"score":0.5234000086784363},{"id":"https://openalex.org/C2777534236","wikidata":"https://www.wikidata.org/wiki/Q310997","display_name":"Taenia","level":3,"score":0.4643999934196472},{"id":"https://openalex.org/C2911037157","wikidata":"https://www.wikidata.org/wiki/Q581102","display_name":"Antiparasitic agent","level":2,"score":0.438400000333786},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.41929998993873596},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.4165000021457672},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.41370001435279846},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.4106000065803528},{"id":"https://openalex.org/C2776243873","wikidata":"https://www.wikidata.org/wiki/Q421230","display_name":"Auranofin","level":3,"score":0.35600000619888306},{"id":"https://openalex.org/C2776375370","wikidata":"https://www.wikidata.org/wiki/Q5090615","display_name":"Chemosensitizer","level":4,"score":0.31520000100135803},{"id":"https://openalex.org/C116263406","wikidata":"https://www.wikidata.org/wiki/Q3299024","display_name":"Acute toxicity","level":3,"score":0.30550000071525574},{"id":"https://openalex.org/C2777230291","wikidata":"https://www.wikidata.org/wiki/Q33551","display_name":"Curcuma","level":2,"score":0.3050999939441681},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.304500013589859},{"id":"https://openalex.org/C2780497538","wikidata":"https://www.wikidata.org/wiki/Q1192006","display_name":"Detoxification (alternative medicine)","level":3,"score":0.30309998989105225},{"id":"https://openalex.org/C2776120743","wikidata":"https://www.wikidata.org/wiki/Q3271540","display_name":"Mechanism of action","level":3,"score":0.28999999165534973},{"id":"https://openalex.org/C2107291","wikidata":"https://www.wikidata.org/wiki/Q14886885","display_name":"Mediator","level":2,"score":0.257099986076355},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.25690001249313354},{"id":"https://openalex.org/C203522944","wikidata":"https://www.wikidata.org/wiki/Q288322","display_name":"Autophagy","level":3,"score":0.2563999891281128},{"id":"https://openalex.org/C538909803","wikidata":"https://www.wikidata.org/wiki/Q116907","display_name":"Glutathione","level":3,"score":0.25589999556541443},{"id":"https://openalex.org/C2777056448","wikidata":"https://www.wikidata.org/wiki/Q285166","display_name":"Oral administration","level":2,"score":0.25290000438690186}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/antiox15101226","doi":"https://doi.org/10.3390/antiox15101226","is_oa":true,"landing_page_url":"https://doi.org/10.3390/antiox15101226","pdf_url":null,"source":{"id":"https://openalex.org/S2737566431","display_name":"Antioxidants","issn_l":"2076-3921","issn":["2076-3921"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13700812","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13700812/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13700812/pdf/antioxidants-15-01226.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants (Basel)","raw_type":"Text"},{"id":"pmid:42939800","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42939800","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants (Basel, Switzerland)","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:071e8169a8fd4c6397e80f2e24cce343","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/071e8169a8fd4c6397e80f2e24cce343","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Antioxidants, Vol 15, Iss 10, p 1226 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/antiox15101226","doi":"https://doi.org/10.3390/antiox15101226","is_oa":true,"landing_page_url":"https://doi.org/10.3390/antiox15101226","pdf_url":null,"source":{"id":"https://openalex.org/S2737566431","display_name":"Antioxidants","issn_l":"2076-3921","issn":["2076-3921"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320318902","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/02hdnbe80"},{"id":"https://openalex.org/F4320323401","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25"},{"id":"https://openalex.org/F4320335100","display_name":"Direcci\u00f3n General de Asuntos del Personal Acad\u00e9mico, Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7214092397.pdf","grobid_xml":"https://content.openalex.org/works/W7214092397.grobid-xml"},"referenced_works_count":53,"referenced_works":["https://openalex.org/W375601794","https://openalex.org/W1441929733","https://openalex.org/W1967691688","https://openalex.org/W1970174702","https://openalex.org/W1987712541","https://openalex.org/W1999440327","https://openalex.org/W2000497093","https://openalex.org/W2005360917","https://openalex.org/W2009115862","https://openalex.org/W2028291647","https://openalex.org/W2031423487","https://openalex.org/W2034762704","https://openalex.org/W2050773334","https://openalex.org/W2073323067","https://openalex.org/W2074380771","https://openalex.org/W2078736001","https://openalex.org/W2092576475","https://openalex.org/W2097933346","https://openalex.org/W2123205017","https://openalex.org/W2141451721","https://openalex.org/W2164297850","https://openalex.org/W2303295096","https://openalex.org/W2318366705","https://openalex.org/W2412912439","https://openalex.org/W2554209253","https://openalex.org/W2761934905","https://openalex.org/W2766906926","https://openalex.org/W2768768130","https://openalex.org/W2790086843","https://openalex.org/W2884385526","https://openalex.org/W2895911641","https://openalex.org/W2947644676","https://openalex.org/W3006698110","https://openalex.org/W3011530534","https://openalex.org/W3021034392","https://openalex.org/W3023473962","https://openalex.org/W3029796528","https://openalex.org/W3136742285","https://openalex.org/W3181034112","https://openalex.org/W4220985947","https://openalex.org/W4223600679","https://openalex.org/W4229582703","https://openalex.org/W4283652784","https://openalex.org/W4293473299","https://openalex.org/W4362458301","https://openalex.org/W4384343056","https://openalex.org/W4394964565","https://openalex.org/W4403500786","https://openalex.org/W4404052531","https://openalex.org/W4407630022","https://openalex.org/W4408319360","https://openalex.org/W4412008346","https://openalex.org/W4413094723"],"related_works":["https://openalex.org/W4283652784","https://openalex.org/W4406081308","https://openalex.org/W2751699552","https://openalex.org/W2157156553","https://openalex.org/W3088103764","https://openalex.org/W2071258560","https://openalex.org/W4389553696","https://openalex.org/W7165125380","https://openalex.org/W4353050757","https://openalex.org/W2009115862"],"abstract_inverted_index":{"cysticerci,":[0],"due":[1],"to":[2,5,42,81],"its":[3,19,23],"ability":[4],"interfere":[6],"with":[7,70,89,118],"the":[8,35,95,109],"parasite's":[9],"redox":[10],"metabolism.":[11],"Free":[12],"curcumin":[13,44,60],"is":[14,87],"highly":[15],"unstable,":[16],"which":[17],"limits":[18],"bioavailability":[20,136],"and":[21,65,100,114,137],"reduces":[22],"efficacy":[24,140],"as":[25,125],"an":[26,62],"anthelmintic":[27],"drug.":[28],"To":[29],"overcome":[30],"these":[31,112],"constraints,":[32],"we":[33],"evaluated":[34],"use":[36],"of":[37,94,111,129,152],"Polycaprolactone-Pluronic\u00a9-F68":[38],"nanoparticles":[39],"(PCL/F68":[40],"NPs)":[41],"improve":[43],"stability":[45],"for":[46,150],"in":[47,61,108],"vitro":[48],"administration":[49],"against":[50],"cysticerci.":[51],"Our":[52],"results":[53],"indicate":[54],"that":[55,142],"PCL/F68":[56],"NPs":[57,104,144],"effectively":[58],"protect":[59],"aqueous":[63],"medium,":[64],"after":[66],"120":[67],"h":[68],"incubation":[69],"10":[71],"\u00b5M":[72],"curcumin-loaded":[73,103],"NPs,":[74],"cysticerci":[75,106],"mortality":[76,107],"was":[77],"100%.":[78],"In":[79],"contrast":[80],"free":[82],"curcumin,":[83],"whose":[84],"cysticidal":[85],"activity":[86],"associated":[88,117],"increased":[90,135],"ROS":[91],"production,":[92],"disruption":[93],"parasitic":[96],"thioredoxin":[97],"antioxidant":[98],"system,":[99],"tegumental":[101],"damage,":[102],"induced":[105],"absence":[110],"effects":[113],"were":[115],"instead":[116],"profound":[119],"nucleolar":[120,123],"alterations,":[121],"implicating":[122],"dysfunction":[124],"a":[126,146],"potential":[127],"mediator":[128],"parasite":[130],"death.":[131],"The":[132],"reduced":[133],"dose,":[134],"enhanced":[138],"antiparasitic":[139],"suggest":[141],"PCL/F68-CUR":[143],"offer":[145],"promising":[147],"therapeutic":[148],"strategy":[149],"treatment":[151],"cysticercosis.":[153]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-09-24T00:00:00"}