{"id":"https://openalex.org/W7214082153","doi":"https://doi.org/10.7759/cureus.116775","title":"Rapidly Progressive Peritoneal Carcinomatosis Originating From Mucinous Appendiceal Adenocarcinoma: A Case Report","display_name":"Rapidly Progressive Peritoneal Carcinomatosis Originating From Mucinous Appendiceal Adenocarcinoma: A Case Report","publication_year":2026,"publication_date":"2026-09-23","ids":{"openalex":"https://openalex.org/W7214082153","doi":"https://doi.org/10.7759/cureus.116775","pmid":"https://pubmed.ncbi.nlm.nih.gov/42921477","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13693441"},"language":"en","primary_location":{"id":"doi:10.7759/cureus.116775","doi":"https://doi.org/10.7759/cureus.116775","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.116775","pdf_url":"https://www.cureus.com/articles/528553-rapidly-progressive-peritoneal-carcinomatosis-originating-from-mucinous-appendiceal-adenocarcinoma-a-case-report.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.cureus.com/articles/528553-rapidly-progressive-peritoneal-carcinomatosis-originating-from-mucinous-appendiceal-adenocarcinoma-a-case-report.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5152572992","display_name":"Cole Verble","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335043937","display_name":"UF Health Shands Hospital","ror":"https://ror.org/03kvbr153","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1335043937","https://openalex.org/I2800717037","https://openalex.org/I33213144","https://openalex.org/I61515104"]},{"id":"https://openalex.org/I2800717037","display_name":"University of Florida Health","ror":"https://ror.org/04tk2gy88","country_code":"US","type":"education","lineage":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]},{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]},{"id":"https://openalex.org/I4210150389","display_name":"UF Health Shands Rehab Hospital","ror":"https://ror.org/049wsgv73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800717037","https://openalex.org/I33213144","https://openalex.org/I4210150389","https://openalex.org/I61515104"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Cole Verble","raw_affiliation_strings":["Physical Medicine and Rehabilitation, University of Florida (UF) Health Shands Hospital, Gainesville, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physical Medicine and Rehabilitation, University of Florida (UF) Health Shands Hospital, Gainesville, USA","institution_ids":["https://openalex.org/I1335043937","https://openalex.org/I2800717037","https://openalex.org/I33213144","https://openalex.org/I4210150389"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5152516819","display_name":"Kalyn Powers Verble","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335043937","display_name":"UF Health Shands Hospital","ror":"https://ror.org/03kvbr153","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1335043937","https://openalex.org/I2800717037","https://openalex.org/I33213144","https://openalex.org/I61515104"]},{"id":"https://openalex.org/I2800717037","display_name":"University of Florida Health","ror":"https://ror.org/04tk2gy88","country_code":"US","type":"education","lineage":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]},{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kalyn Powers Verble","raw_affiliation_strings":["Pharmacology and Therapeutics, University of Florida (UF) Health Shands Hospital, Gainesville, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacology and Therapeutics, University of Florida (UF) Health Shands Hospital, Gainesville, USA","institution_ids":["https://openalex.org/I1335043937","https://openalex.org/I2800717037","https://openalex.org/I33213144"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5152572992"],"corresponding_institution_ids":["https://openalex.org/I1335043937","https://openalex.org/I2800717037","https://openalex.org/I33213144","https://openalex.org/I4210150389"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.71953271,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"18","issue":"9","first_page":"e116775","last_page":"e116775"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12064","display_name":"Intraperitoneal and Appendiceal Malignancies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12064","display_name":"Intraperitoneal and Appendiceal Malignancies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11473","display_name":"Appendicitis Diagnosis and Management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/appendiceal-mucocele","display_name":"appendiceal mucocele","score":0.8980000019073486},{"id":"https://openalex.org/keywords/peritoneal-metastases","display_name":"peritoneal carcinomatosis","score":0.9610000252723694},{"id":"https://openalex.org/keywords/pseudomyxoma-peritonei","display_name":"pseudomyxoma peritonei","score":0.9980000257492065},{"id":"https://openalex.org/keywords/rapidly-progressive-disease","display_name":"rapidly progressive disease","score":0.6669999957084656},{"id":"https://openalex.org/keywords/cytoreductive-surgery","display_name":"cytoreductive surgery","score":0.8360000252723694},{"id":"https://openalex.org/keywords/hyperthermic-intraperitoneal-chemotherapy","display_name":"hyperthermic intraperitoneal chemotherapy","score":0.9629999995231628},{"id":"https://openalex.org/keywords/palliative-chemotherapy","display_name":"palliative chemotherapy","score":0.949999988079071},{"id":"https://openalex.org/keywords/early-detection","display_name":"early detection","score":0.7139999866485596},{"id":"https://openalex.org/keywords/young-adults","display_name":"young adults","score":0.5270000100135803},{"id":"https://openalex.org/keywords/appendiceal-neoplasms","display_name":"appendiceal neoplasms","score":0.6010000109672546}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9886000156402588},{"id":"https://openalex.org/C2991818862","wikidata":"https://www.wikidata.org/wiki/Q2071182","display_name":"Peritoneal carcinomatosis","level":4,"score":0.8355000019073486},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.5483999848365784},{"id":"https://openalex.org/C2780898957","wikidata":"https://www.wikidata.org/wiki/Q574694","display_name":"Pseudomyxoma peritonei","level":3,"score":0.3393000066280365},{"id":"https://openalex.org/C2776206344","wikidata":"https://www.wikidata.org/wiki/Q837583","display_name":"Carcinosis","level":5,"score":0.33709999918937683},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.32120001316070557},{"id":"https://openalex.org/C2781182431","wikidata":"https://www.wikidata.org/wiki/Q356033","display_name":"Adenocarcinoma","level":3,"score":0.3089999854564667},{"id":"https://openalex.org/C544519230","wikidata":"https://www.wikidata.org/wiki/Q32566","display_name":"Computed tomography","level":2,"score":0.30889999866485596},{"id":"https://openalex.org/C2908737533","wikidata":"https://www.wikidata.org/wiki/Q9629","display_name":"Peritoneal diseases","level":2,"score":0.2985000014305115},{"id":"https://openalex.org/C2776001837","wikidata":"https://www.wikidata.org/wiki/Q9629","display_name":"Peritoneum","level":2,"score":0.26440000534057617},{"id":"https://openalex.org/C61434518","wikidata":"https://www.wikidata.org/wiki/Q932510","display_name":"General surgery","level":1,"score":0.2632000148296356},{"id":"https://openalex.org/C2779983558","wikidata":"https://www.wikidata.org/wiki/Q9597","display_name":"Abdomen","level":2,"score":0.2531999945640564},{"id":"https://openalex.org/C2776364125","wikidata":"https://www.wikidata.org/wiki/Q9656","display_name":"Appendix","level":2,"score":0.25220000743865967},{"id":"https://openalex.org/C2780801072","wikidata":"https://www.wikidata.org/wiki/Q837512","display_name":"Differential diagnosis","level":2,"score":0.25189998745918274}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.7759/cureus.116775","doi":"https://doi.org/10.7759/cureus.116775","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.116775","pdf_url":"https://www.cureus.com/articles/528553-rapidly-progressive-peritoneal-carcinomatosis-originating-from-mucinous-appendiceal-adenocarcinoma-a-case-report.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13693441","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13693441/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13693441/pdf/cureus-0018-00000116775.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Text"},{"id":"pmid:42921477","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42921477","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Case Reports"}],"best_oa_location":{"id":"doi:10.7759/cureus.116775","doi":"https://doi.org/10.7759/cureus.116775","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.116775","pdf_url":"https://www.cureus.com/articles/528553-rapidly-progressive-peritoneal-carcinomatosis-originating-from-mucinous-appendiceal-adenocarcinoma-a-case-report.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7214082153.pdf","grobid_xml":"https://content.openalex.org/works/W7214082153.grobid-xml"},"referenced_works_count":11,"referenced_works":["https://openalex.org/W17791541","https://openalex.org/W1990395355","https://openalex.org/W2069521761","https://openalex.org/W2228301698","https://openalex.org/W2561960355","https://openalex.org/W2732048514","https://openalex.org/W3197340417","https://openalex.org/W4283122560","https://openalex.org/W4379599690","https://openalex.org/W4391066691","https://openalex.org/W4396633603"],"related_works":["https://openalex.org/W4402909926","https://openalex.org/W2977689054","https://openalex.org/W3093566625","https://openalex.org/W4312284707","https://openalex.org/W2474500273","https://openalex.org/W4311795834","https://openalex.org/W7120095569","https://openalex.org/W4313436383","https://openalex.org/W2438943298","https://openalex.org/W3002720215"],"abstract_inverted_index":{"Malignant":[0],"neoplasms":[1,8],"of":[2,36,172,196,199],"the":[3,63,66,78,87,120,139,159,194,220],"appendix":[4,64],"are":[5,71,230],"rare.":[6],"These":[7],"can":[9,91],"be":[10,166],"further":[11,92],"delineated":[12],"into":[13,94,138],"either":[14],"colonic":[15],"or":[16,182],"cystic":[17,20],"types.":[18],"A":[19,110],"type":[21],"appendiceal":[22,30,40,46],"tumor":[23],"is":[24,43,60,98],"often":[25,53],"referred":[26],"to":[27,33,77,131,143,158,165,178,188,232],"as":[28],"an":[29],"mucocele":[31,47],"due":[32],"its":[34],"production":[35],"jelly-like":[37],"mucus.":[38],"Mucinous":[39],"adenocarcinoma":[41],"(MAA)":[42],"a":[44],"malignant":[45],"associated":[48],"with":[49,73,101,113,136,225],"nonspecific":[50],"symptoms":[51],"and":[52,69,105,145,156],"found":[54,84,130],"incidentally":[55],"when":[56],"other":[57],"abdominal":[58,152],"work-up":[59],"performed.":[61,167,218],"If":[62,83],"ruptures,":[65],"peritoneal":[67,95,140,146,211,226],"cavity":[68,141,153],"organs":[70],"coated":[72],"mucus-producing":[74],"cells,":[75],"leading":[76,142],"complication":[79],"pseudomyxoma":[80],"peritonei":[81],"(PMP).":[82],"late":[85],"in":[86,150,186,206],"disease":[88],"progression,":[89],"it":[90,176],"develop":[93],"carcinomatosis,":[96,227],"which":[97],"typically":[99],"treated":[100],"cytoreductive":[102],"surgery":[103],"(CRS)":[104],"heated":[106],"intraperitoneal":[107],"chemotherapy":[108],"(HIPEC).":[109],"28-year-old":[111],"male":[112],"no":[114],"past":[115],"medical":[116],"history":[117],"arrived":[118],"at":[119],"emergency":[121],"department":[122],"for":[123],"longstanding":[124],"constipation.":[125],"Upon":[126],"workup,":[127],"he":[128],"was":[129,163],"have":[132],"stage":[133],"IV":[134],"MAA":[135],"dissemination":[137],"PMP":[144],"carcinomatosis.":[147],"The":[148],"mucin":[149,184],"his":[151],"had":[154],"proliferated":[155],"solidified":[157],"point":[160],"where":[161],"CRS/HIPEC":[162,215],"unable":[164],"He":[168],"received":[169],"multiple":[170],"rounds":[171],"palliative":[173],"chemotherapy;":[174],"however,":[175],"failed":[177],"shrink":[179],"any":[180],"tumors":[181],"lessen":[183],"burden":[185],"order":[187],"receive":[189,233],"CRS/HIPEC.":[190,234],"This":[191],"case":[192],"demonstrates":[193],"importance":[195],"early":[197],"detection":[198],"MAA.":[200],"It":[201],"also":[202],"illustrates":[203],"that":[204],"even":[205],"healthy":[207],"young":[208],"adults,":[209],"advanced":[210],"carcinomatosis":[212],"may":[213],"impede":[214],"from":[216],"being":[217],"In":[219],"current":[221],"literature,":[222],"most":[223],"patients":[224],"unless":[228],"contraindicated,":[229],"able":[231]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-09-24T00:00:00"}