{"id":"https://openalex.org/W7214032006","doi":"https://doi.org/10.48550/arxiv.2609.24718","title":"A Federated Artificial Intelligence Framework for Optimizing Pancreatic Cancer Treatment - Strategy Update","display_name":"A Federated Artificial Intelligence Framework for Optimizing Pancreatic Cancer Treatment - Strategy Update","publication_year":2026,"publication_date":"2026-09-21","ids":{"openalex":"https://openalex.org/W7214032006","doi":"https://doi.org/10.48550/arxiv.2609.24718"},"language":"en","primary_location":{"id":"pmh:oai:arXiv.org:2609.24718","doi":null,"is_oa":true,"landing_page_url":"https://arxiv.org/abs/2609.24718","pdf_url":"https://arxiv.org/pdf/2609.24718","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["arxiv","datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://arxiv.org/pdf/2609.24718","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087041634","display_name":"Anne-Christin Hauschild","orcid":"https://orcid.org/0000-0002-7499-4373","observed_orcids":["https://orcid.org/0000-0002-7499-4373"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hauschild, Anne-Christin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5132707314","display_name":"Amirreza Aleyasin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17937529","display_name":"German Cancer Research Center","ror":"https://ror.org/04cdgtt98","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I17937529"]},{"id":"https://openalex.org/I2802619606","display_name":"TUM Klinikum","ror":"https://ror.org/04jc43x05","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802619606","https://openalex.org/I62916508"]},{"id":"https://openalex.org/I4210116730","display_name":"Universit\u00e4tsmedizin G\u00f6ttingen","ror":"https://ror.org/021ft0n22","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210116730"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Aleyasin, Amirreza","raw_affiliation_strings":["University Medical Center G\u00f6ttingen , Department of Medical Informatics , G\u00f6ttingen , Germany;","partnership between DKFZ and University Hospital Klinikum rechts der Isar , Munich , Germany;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Medical Center G\u00f6ttingen , Department of Medical Informatics , G\u00f6ttingen , Germany;","institution_ids":["https://openalex.org/I4210116730"]},{"raw_affiliation_string":"partnership between DKFZ and University Hospital Klinikum rechts der Isar , Munich , Germany;","institution_ids":["https://openalex.org/I17937529","https://openalex.org/I2802619606"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114227155","display_name":"Nils Beyer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Beyer, Nils H.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085351416","display_name":"Lisa Fricke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802619606","display_name":"TUM Klinikum","ror":"https://ror.org/04jc43x05","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802619606","https://openalex.org/I62916508"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Fricke, Lisa","raw_affiliation_strings":["TUM School of Medicine and Health , Department of Clinical Medicine -Clinical Department for Internal Medicine II , University Medical Center , Technical University of Munich , Munich , Germany;","Translational Pancreatic Cancer Research Center , TUM School of Medicine and Health , Department of Clinical Medicine -Clinical Department for Internal Medicine II , TUM University Hospital , Technical University of Munich , Munich , Germany;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"TUM School of Medicine and Health , Department of Clinical Medicine -Clinical Department for Internal Medicine II , University Medical Center , Technical University of Munich , Munich , Germany;","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"Translational Pancreatic Cancer Research Center , TUM School of Medicine and Health , Department of Clinical Medicine -Clinical Department for Internal Medicine II , TUM University Hospital , Technical University of Munich , Munich , Germany;","institution_ids":["https://openalex.org/I2802619606","https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066191670","display_name":"Jonas H\u00fcgel","orcid":"https://orcid.org/0000-0002-4183-1287","observed_orcids":["https://orcid.org/0000-0002-4183-1287"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H\u00fcgel, Jonas","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102779021","display_name":"Maryam Moradpour","orcid":"https://orcid.org/0009-0001-0906-5842","observed_orcids":["https://orcid.org/0009-0001-0906-5842"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Moradpour, Maryam","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029279801","display_name":"Anh-Tien Nguyen","orcid":"https://orcid.org/0000-0001-8445-2191","observed_orcids":["https://orcid.org/0000-0001-8445-2191"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nguyen, Anh-Tien","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010225287","display_name":"Youngjun Park","orcid":"https://orcid.org/0000-0002-9963-7014","observed_orcids":["https://orcid.org/0000-0002-9963-7014"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Park, Youngjun","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087146329","display_name":"Sophia Rheinl\u00e4nder","orcid":"https://orcid.org/0000-0002-5406-4427","observed_orcids":["https://orcid.org/0000-0002-5406-4427"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rheinl\u00e4nder, Sophia","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017944645","display_name":"Tim Bei\u00dfbarth","orcid":"https://orcid.org/0000-0001-6509-2143","observed_orcids":["https://orcid.org/0000-0001-6509-2143"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Beissbarth, Tim","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045288328","display_name":"Elisabeth He\u00dfmann","orcid":"https://orcid.org/0000-0002-9462-1291","observed_orcids":["https://orcid.org/0000-0002-9462-1291"]},"institutions":[{"id":"https://openalex.org/I4210116730","display_name":"Universit\u00e4tsmedizin G\u00f6ttingen","ror":"https://ror.org/021ft0n22","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210116730"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hessmann, Elisabeth","raw_affiliation_strings":["University Medical Center G\u00f6ttingen , Clinical Research Group 5002 (CRU5002) , G\u00f6ttingen , Germany;","University Medical Center G\u00f6ttingen , Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology , G\u00f6ttingen , Germany;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Medical Center G\u00f6ttingen , Clinical Research Group 5002 (CRU5002) , G\u00f6ttingen , Germany;","institution_ids":["https://openalex.org/I4210116730"]},{"raw_affiliation_string":"University Medical Center G\u00f6ttingen , Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology , G\u00f6ttingen , Germany;","institution_ids":["https://openalex.org/I4210116730"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5153529969","display_name":"Martin Middeke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161103922","display_name":"Philipps University of Marburg","ror":"https://ror.org/01rdrb571","country_code":"DE","type":"education","lineage":["https://openalex.org/I161103922"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Middeke, Martin","raw_affiliation_strings":["Philipps-University Marburg , Comprehensive Cancer Center , Marburg , Germany;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Philipps-University Marburg , Comprehensive Cancer Center , Marburg , Germany;","institution_ids":["https://openalex.org/I161103922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061882954","display_name":"Matthias Lauth","orcid":"https://orcid.org/0000-0001-5922-5384","observed_orcids":["https://orcid.org/0000-0001-5922-5384"]},"institutions":[{"id":"https://openalex.org/I161103922","display_name":"Philipps University of Marburg","ror":"https://ror.org/01rdrb571","country_code":"DE","type":"education","lineage":["https://openalex.org/I161103922"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Lauth, Matthias","raw_affiliation_strings":["Philipps-University Marburg , Clinic for Gastroenterology, Endocrinology and Metabolism , Marburg , Germany;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Philipps-University Marburg , Clinic for Gastroenterology, Endocrinology and Metabolism , Marburg , Germany;","institution_ids":["https://openalex.org/I161103922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073445337","display_name":"Maximilian Reichert","orcid":"https://orcid.org/0000-0002-8611-5639","observed_orcids":["https://orcid.org/0000-0002-8611-5639","https://orcid.org/0000-0003-0111-2445"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Reichert, Maximilian","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5013507281","display_name":"Ulrich Sax","orcid":"https://orcid.org/0000-0002-8188-3495","observed_orcids":["https://orcid.org/0000-0002-8188-3495"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sax, Ulrich","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10764","display_name":"Privacy-Preserving Technologies in Data","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10764","display_name":"Privacy-Preserving Technologies in Data","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/federated-learning","display_name":"federated learning","score":0.9950000047683716},{"id":"https://openalex.org/keywords/pancreatic-cancer","display_name":"pancreatic cancer","score":0.9919999837875366},{"id":"https://openalex.org/keywords/treatment-optimization","display_name":"treatment optimization","score":0.3889999985694885},{"id":"https://openalex.org/keywords/cancer-subtyping","display_name":"cancer subtyping","score":0.7070000171661377},{"id":"https://openalex.org/keywords/data-privacy","display_name":"data privacy","score":0.5920000076293945},{"id":"https://openalex.org/keywords/gdpr-compliance","display_name":"GDPR compliance","score":0.8920000195503235},{"id":"https://openalex.org/keywords/overlapping-features","display_name":"overlapping features","score":0.5170000195503235},{"id":"https://openalex.org/keywords/docker-containers","display_name":"Docker containers","score":0.5529999732971191},{"id":"https://openalex.org/keywords/ethical-approval","display_name":"research ethics approval","score":0.7620000243186951},{"id":"https://openalex.org/keywords/multimodal-data","display_name":"multimodal data","score":0.6330000162124634}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7152000069618225},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.4787999987602234},{"id":"https://openalex.org/C61423126","wikidata":"https://www.wikidata.org/wiki/Q187432","display_name":"Scripting language","level":2,"score":0.4652000069618225},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.45239999890327454},{"id":"https://openalex.org/C2779965156","wikidata":"https://www.wikidata.org/wiki/Q5227350","display_name":"Data sharing","level":3,"score":0.43689998984336853},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.41269999742507935},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.40799999237060547},{"id":"https://openalex.org/C2780210213","wikidata":"https://www.wikidata.org/wiki/Q212961","display_name":"Pancreatic cancer","level":3,"score":0.3865000009536743},{"id":"https://openalex.org/C184356942","wikidata":"https://www.wikidata.org/wiki/Q830382","display_name":"Best practice","level":2,"score":0.37439998984336853},{"id":"https://openalex.org/C2164484","wikidata":"https://www.wikidata.org/wiki/Q5170150","display_name":"Core (optical fiber)","level":2,"score":0.35420000553131104},{"id":"https://openalex.org/C58489278","wikidata":"https://www.wikidata.org/wiki/Q1172284","display_name":"Data set","level":2,"score":0.3528999984264374},{"id":"https://openalex.org/C93518851","wikidata":"https://www.wikidata.org/wiki/Q180160","display_name":"Metadata","level":2,"score":0.3434000015258789},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.32910001277923584},{"id":"https://openalex.org/C2779530757","wikidata":"https://www.wikidata.org/wiki/Q1207505","display_name":"Quality (philosophy)","level":2,"score":0.3222000002861023},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.3197999894618988},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3158999979496002},{"id":"https://openalex.org/C2780440489","wikidata":"https://www.wikidata.org/wiki/Q5227278","display_name":"Data-driven","level":2,"score":0.3102000057697296},{"id":"https://openalex.org/C72634772","wikidata":"https://www.wikidata.org/wiki/Q386824","display_name":"Data integration","level":2,"score":0.30820000171661377},{"id":"https://openalex.org/C20162079","wikidata":"https://www.wikidata.org/wiki/Q1151406","display_name":"Case-based reasoning","level":2,"score":0.30090001225471497},{"id":"https://openalex.org/C165064840","wikidata":"https://www.wikidata.org/wiki/Q1321061","display_name":"Matching (statistics)","level":2,"score":0.29280000925064087},{"id":"https://openalex.org/C774472","wikidata":"https://www.wikidata.org/wiki/Q6760393","display_name":"Margin (machine learning)","level":2,"score":0.28850001096725464},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.28679999709129333},{"id":"https://openalex.org/C3019816032","wikidata":"https://www.wikidata.org/wiki/Q2575340","display_name":"Cancer treatment","level":3,"score":0.2851000130176544},{"id":"https://openalex.org/C24756922","wikidata":"https://www.wikidata.org/wiki/Q1757694","display_name":"Data quality","level":3,"score":0.2702000141143799},{"id":"https://openalex.org/C123201435","wikidata":"https://www.wikidata.org/wiki/Q456632","display_name":"Information privacy","level":2,"score":0.26969999074935913},{"id":"https://openalex.org/C22467394","wikidata":"https://www.wikidata.org/wiki/Q849359","display_name":"Multidisciplinary approach","level":2,"score":0.26600000262260437},{"id":"https://openalex.org/C2776604539","wikidata":"https://www.wikidata.org/wiki/Q6423395","display_name":"Knowledge sharing","level":2,"score":0.26409998536109924},{"id":"https://openalex.org/C71745522","wikidata":"https://www.wikidata.org/wiki/Q2476929","display_name":"Confidentiality","level":2,"score":0.25949999690055847}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:arXiv.org:2609.24718","doi":null,"is_oa":true,"landing_page_url":"https://arxiv.org/abs/2609.24718","pdf_url":"https://arxiv.org/pdf/2609.24718","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"doi:10.48550/arxiv.2609.24718","doi":"https://doi.org/10.48550/arxiv.2609.24718","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.2609.24718","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Preprint"}],"best_oa_location":{"id":"pmh:oai:arXiv.org:2609.24718","doi":null,"is_oa":true,"landing_page_url":"https://arxiv.org/abs/2609.24718","pdf_url":"https://arxiv.org/pdf/2609.24718","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"sustainable_development_goals":[{"score":0.8999999761581421,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3293522367","display_name":null,"funder_award_id":"KFO-5002","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G3865379469","display_name":null,"funder_award_id":"01VSF20014","funder_id":"https://openalex.org/F4320328691","funder_display_name":"Gemeinsame Bundesausschuss"},{"id":"https://openalex.org/G4473214921","display_name":"KFO 5002: Charakterisierung und Targeting der Genomdynamik f\u00fcr eine Subtypspezifische Therapie des Pankreaskarzinoms","funder_award_id":"426671079","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G5529525317","display_name":null,"funder_award_id":"01KD2208A","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G5830758852","display_name":null,"funder_award_id":"KFO325","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G7655486867","display_name":"NFDI4Health \u2013 Nationale Forschungsdateninfrastruktur f\u00fcr personenbezogene Gesundheitsdaten","funder_award_id":"442326535","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G7816388438","display_name":null,"funder_award_id":"01KD2414A","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G8969968981","display_name":"KFO 325: Klinische Relevanz von TumorStroma Interaktionen im Pankreaskarzinom","funder_award_id":"329116008","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320328691","display_name":"Gemeinsame Bundesausschuss","ror":"https://ror.org/008c2qm47"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7214032006.pdf","grobid_xml":"https://content.openalex.org/works/W7214032006.grobid-xml"},"referenced_works_count":9,"referenced_works":["https://openalex.org/W2128349406","https://openalex.org/W2218465138","https://openalex.org/W2606335860","https://openalex.org/W3172444156","https://openalex.org/W4282045368","https://openalex.org/W4317952770","https://openalex.org/W4399378978","https://openalex.org/W4402279211","https://openalex.org/W6927352016"],"related_works":["https://openalex.org/W7146938136","https://openalex.org/W7154590238","https://openalex.org/W7204998348","https://openalex.org/W4411150076","https://openalex.org/W7125198599","https://openalex.org/W4387849960","https://openalex.org/W4384826876","https://openalex.org/W4408514167","https://openalex.org/W7113550047","https://openalex.org/W4403914197"],"abstract_inverted_index":{"While":[0],"a":[1,38,55,132,140,159,181],"centralized":[2],"approach":[3,41,255],"involving":[4],"patient":[5],"consent":[6],"to":[7,36,42,74,119,173,201,272],"collect":[8],"and":[9,20,44,67,70,78,84,102,121,129,143,204,243],"analyze":[10],"data":[11,18,124,191,226,265],"centrally":[12,141],"would":[13],"theoretically":[14],"offer":[15],"the":[16,51,61,64,100,107,114,123,151,174,187,209,235,257],"best":[17],"quality":[19],"predictive":[21],"performance,":[22],"it":[23],"is":[24,195],"not":[25],"always":[26],"feasible":[27],"in":[28,88,98,131,137,180,208,256],"practice.":[29],"Federated":[30],"Learning":[31],"(FL)":[32],"architectures":[33,242],"have":[34,118,248],"shown":[35],"be":[37,206,268],"very":[39],"promising":[40],"use":[43],"access":[45],"distributed":[46],"disease":[47],"related":[48,72],"resources":[49],"within":[50],"GDPR":[52],"boundaries.":[53],"In":[54],"previous":[56],"case":[57,139],"report,":[58],"we":[59,117,222],"described":[60],"preconditions":[62],"at":[63],"participating":[65,115],"sites":[66,274],"necessary":[68],"administrative":[69],"process":[71],"steps":[73],"prepare":[75],"data,":[76],"people":[77],"infrastructure":[79],"for":[80,198,234,239,245],"improving":[81],"subtype":[82],"identification":[83],"assessing":[85],"treatment":[86],"options":[87],"pancreatic":[89],"cancer.":[90],"We":[91,157],"update":[92],"this":[93,254],"report":[94],"sharing":[95],"our":[96,138],"experience":[97],"tackling":[99],"challenges":[101],"show":[103],"preliminary":[104],"results":[105],"of":[106],"actual":[108],"federated":[109],"learning":[110],"AI":[111],"pipelines.":[112],"At":[113],"sites,":[116],"identify":[120],"annotate":[122],"being":[125],"accessible":[126],"after":[127],"extraction":[128],"transformation":[130],"local":[133,155,166,175],"FL":[134,152,162,210,213],"hub":[135],"-":[136],"developed":[142,161],"distributively":[144],"deployed":[145],"Docker":[146],"container.":[147],"This":[148],"container":[149],"comprises":[150],"scripts":[153],"generating":[154],"models.":[156],"apply":[158],"newly":[160],"algorithm":[163],"considering":[164],"all":[165],"features,":[167],"including":[168,230,262],"partial":[169],"overlapping":[170,219],"features":[171,220],"specific":[172],"sites.":[176],"Theoretically,":[177],"an":[178],"annotation":[179],"cancer":[182,202],"setting":[183],"should":[184,267],"succeed":[185],"using":[186],"German":[188],"oncology":[189],"core":[190],"set":[192],"(oBDS),":[193],"which":[194],"already":[196],"utilized":[197],"mandatory":[199],"reporting":[200],"registries,":[203],"can":[205],"sustained":[207],"setting.":[211],"The":[212],"algorithms":[214],"deal":[215],"robustly":[216],"with":[217,224],"partially":[218],"as":[221],"showed":[223],"public":[225],"sets.":[227],"Major":[228],"roadblocks":[229],"straightening":[231],"operational":[232],"concepts":[233],"infrastructures,":[236],"ethics":[237],"approval":[238],"such":[240],"novel":[241],"support":[244],"every":[246],"site":[247],"been":[249],"addressed.":[250],"However,":[251],"scaling":[252],"up":[253],"future":[258],"faces":[259],"hurdles;":[260],"while":[261],"broader":[263],"multi-modal":[264],"sets":[266],"feasible,":[269],"large-scale":[270],"deployment":[271],"more":[273],"remains":[275],"challenging.":[276]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2026-09-23T00:00:00"}