{"id":"https://openalex.org/W7214020286","doi":"https://doi.org/10.17179/excli2026-9310","title":"Metabolic dysfunction-associated steatotic liver disease: Pathogenesis, complications and pharmacological treatment","display_name":"Metabolic dysfunction-associated steatotic liver disease: Pathogenesis, complications and pharmacological treatment","publication_year":2026,"publication_date":"2026-09-22","ids":{"openalex":"https://openalex.org/W7214020286","doi":"https://doi.org/10.17179/excli2026-9310","pmid":"https://pubmed.ncbi.nlm.nih.gov/42985147","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13731909"},"language":"en","primary_location":{"id":"doi:10.17179/excli2026-9310","doi":"https://doi.org/10.17179/excli2026-9310","is_oa":true,"landing_page_url":"https://doi.org/10.17179/excli2026-9310","pdf_url":null,"source":{"id":"https://openalex.org/S39273986","display_name":"EXCLI journal","issn_l":"1611-2156","issn":["1611-2156"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","ddh","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310313779","host_organization_name":"IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund","host_organization_lineage":["https://openalex.org/P4310313779"],"host_organization_lineage_names":["IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EXCLI Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.17179/excli2026-9310","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5152471557","display_name":"Kyung-Soo Kim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134376","display_name":"CHA University Bundang Medical Center","ror":"https://ror.org/04nbqb988","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210134376","https://openalex.org/I4210148737","https://openalex.org/I4405258985"]},{"id":"https://openalex.org/I4210148737","display_name":"CHA University","ror":"https://ror.org/04yka3j04","country_code":"KR","type":"education","lineage":["https://openalex.org/I4210148737","https://openalex.org/I4405258985"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kyung-Soo Kim","raw_affiliation_strings":["Department of Internal Medicine, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, South Korea"],"raw_orcid":"https://orcid.org/0000-0002-7738-2284","affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, South Korea","institution_ids":["https://openalex.org/I4210134376","https://openalex.org/I4210148737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5152478213","display_name":"Soo Lim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]},{"id":"https://openalex.org/I2803058125","display_name":"Seoul National University Bundang Hospital","ror":"https://ror.org/00cb3km46","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I139264467","https://openalex.org/I2802835388","https://openalex.org/I2803058125"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Soo Lim","raw_affiliation_strings":["Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea","institution_ids":["https://openalex.org/I139264467","https://openalex.org/I2803058125"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5152466451","display_name":"Cheol-Young Park","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210103535","display_name":"Kangbuk Samsung Hospital","ror":"https://ror.org/013e76m06","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I2250650973","https://openalex.org/I2802194831","https://openalex.org/I4210103535"]},{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Cheol-Young Park","raw_affiliation_strings":["Division of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea"],"raw_orcid":"https://orcid.org/0000-0002-9415-9965","affiliations":[{"raw_affiliation_string":"Division of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea","institution_ids":["https://openalex.org/I4210103535","https://openalex.org/I848706"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5152478213"],"corresponding_institution_ids":["https://openalex.org/I139264467","https://openalex.org/I2803058125"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.6536767,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"25","issue":null,"first_page":"1488","last_page":"1512"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/non-alcoholic-fatty-liver-disease","display_name":"non-alcoholic fatty liver disease","score":0.9330000281333923},{"id":"https://openalex.org/keywords/hepatic-de-novo-lipogenesis","display_name":"hepatic de novo lipogenesis","score":0.9269999861717224},{"id":"https://openalex.org/keywords/adipose-tissue-dysfunction","display_name":"adipose tissue dysfunction","score":0.9950000047683716},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.8799999952316284},{"id":"https://openalex.org/keywords/epigenetic-mechanisms","display_name":"epigenetic mechanisms","score":0.9049999713897705},{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.8410000205039978},{"id":"https://openalex.org/keywords/cardiometabolic-disease","display_name":"cardiometabolic disease","score":0.9309999942779541},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9890000224113464},{"id":"https://openalex.org/keywords/weight-loss","display_name":"weight loss","score":0.628000020980835},{"id":"https://openalex.org/keywords/hepatic-steatosis","display_name":"hepatic steatosis","score":0.7200000286102295},{"id":"https://openalex.org/keywords/liver-fibrosis","display_name":"liver fibrosis","score":0.968999981880188},{"id":"https://openalex.org/keywords/resmetirom","display_name":"resmetirom","score":0.9319999814033508},{"id":"https://openalex.org/keywords/semaglutide","display_name":"semaglutide","score":0.996999979019165},{"id":"https://openalex.org/keywords/masld-screening","display_name":"MASLD screening","score":0.699999988079071}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8828999996185303},{"id":"https://openalex.org/C2776175330","wikidata":"https://www.wikidata.org/wiki/Q1365091","display_name":"Steatosis","level":2,"score":0.6898000240325928},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.5913000106811523},{"id":"https://openalex.org/C2779478299","wikidata":"https://www.wikidata.org/wiki/Q2335423","display_name":"Steatohepatitis","level":4,"score":0.5889000296592712},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.5852000117301941},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.5166000127792358},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5058000087738037},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.4521999955177307},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4496000111103058},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.44699999690055847},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.43380001187324524},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.41940000653266907},{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.4165000021457672},{"id":"https://openalex.org/C544821477","wikidata":"https://www.wikidata.org/wiki/Q718113","display_name":"Weight loss","level":3,"score":0.40959998965263367},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.38659998774528503},{"id":"https://openalex.org/C2777075537","wikidata":"https://www.wikidata.org/wiki/Q929737","display_name":"Liver disease","level":2,"score":0.37119999527931213},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.364300012588501},{"id":"https://openalex.org/C141359234","wikidata":"https://www.wikidata.org/wiki/Q2734301","display_name":"Lipogenesis","level":3,"score":0.33489999175071716},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.33239999413490295},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3122999966144562},{"id":"https://openalex.org/C44353895","wikidata":"https://www.wikidata.org/wiki/Q6556772","display_name":"Lipotoxicity","level":4,"score":0.3052999973297119},{"id":"https://openalex.org/C2779091943","wikidata":"https://www.wikidata.org/wiki/Q1079120","display_name":"Hyperlipidemia","level":3,"score":0.2896000146865845},{"id":"https://openalex.org/C2992518758","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Fat accumulation","level":3,"score":0.2842000126838684},{"id":"https://openalex.org/C2991848491","wikidata":"https://www.wikidata.org/wiki/Q2351083","display_name":"Metabolic disease","level":2,"score":0.27900001406669617},{"id":"https://openalex.org/C2909478654","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Atherosclerotic cardiovascular disease","level":3,"score":0.2694999873638153},{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.26109999418258667},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.25529998540878296},{"id":"https://openalex.org/C2776954865","wikidata":"https://www.wikidata.org/wiki/Q1546498","display_name":"Nonalcoholic fatty liver disease","level":4,"score":0.25450000166893005}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.17179/excli2026-9310","doi":"https://doi.org/10.17179/excli2026-9310","is_oa":true,"landing_page_url":"https://doi.org/10.17179/excli2026-9310","pdf_url":null,"source":{"id":"https://openalex.org/S39273986","display_name":"EXCLI journal","issn_l":"1611-2156","issn":["1611-2156"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","ddh","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310313779","host_organization_name":"IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund","host_organization_lineage":["https://openalex.org/P4310313779"],"host_organization_lineage_names":["IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EXCLI Journal","raw_type":"journal-article"},{"id":"pmh:oai:www.excli.de:article/9310","doi":null,"is_oa":true,"landing_page_url":"https://www.excli.de/excli/article/view/9310","pdf_url":"https://www.excli.de/excli/article/download/9310/5849","source":{"id":"https://openalex.org/S39273986","display_name":"EXCLI journal","issn_l":"1611-2156","issn":["1611-2156"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","ddh","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310313779","host_organization_name":"IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund","host_organization_lineage":["https://openalex.org/P4310313779"],"host_organization_lineage_names":["IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"1611-2156","raw_type":"info:eu-repo/semantics/article"},{"id":"pmid:42985147","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42985147","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EXCLI journal","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13731909","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13731909/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EXCLI J","raw_type":"Text"},{"id":"doi:10.17179/excli2026-9310","doi":"https://doi.org/10.17179/excli2026-9310","is_oa":true,"landing_page_url":"https://doi.org/10.17179/excli2026-9310","pdf_url":null,"source":{"id":"https://openalex.org/S7407053513","display_name":"Leibniz-Institut f\u00fcr Arbeitsforschung an der TU Dortmund (IfADo)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.17179/excli2026-9310","doi":"https://doi.org/10.17179/excli2026-9310","is_oa":true,"landing_page_url":"https://doi.org/10.17179/excli2026-9310","pdf_url":null,"source":{"id":"https://openalex.org/S39273986","display_name":"EXCLI journal","issn_l":"1611-2156","issn":["1611-2156"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","ddh","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310313779","host_organization_name":"IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund","host_organization_lineage":["https://openalex.org/P4310313779"],"host_organization_lineage_names":["IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EXCLI Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7214020286.pdf","grobid_xml":"https://content.openalex.org/works/W7214020286.grobid-xml"},"referenced_works_count":159,"referenced_works":["https://openalex.org/W144423133","https://openalex.org/W1856151485","https://openalex.org/W1964572117","https://openalex.org/W1965423912","https://openalex.org/W1967041777","https://openalex.org/W1967972402","https://openalex.org/W1978898901","https://openalex.org/W1980719167","https://openalex.org/W1980770174","https://openalex.org/W1985592156","https://openalex.org/W1997425045","https://openalex.org/W1997865776","https://openalex.org/W2001837599","https://openalex.org/W2008082500","https://openalex.org/W2009559800","https://openalex.org/W2010662354","https://openalex.org/W2029811522","https://openalex.org/W2060870400","https://openalex.org/W2064387090","https://openalex.org/W2068226015","https://openalex.org/W2071867050","https://openalex.org/W2074677264","https://openalex.org/W2079337704","https://openalex.org/W2091106363","https://openalex.org/W2095235238","https://openalex.org/W2096386481","https://openalex.org/W2097270759","https://openalex.org/W2102392334","https://openalex.org/W2111946630","https://openalex.org/W2115862579","https://openalex.org/W2120056458","https://openalex.org/W2124023774","https://openalex.org/W2148537305","https://openalex.org/W2151490108","https://openalex.org/W2151769300","https://openalex.org/W2155259040","https://openalex.org/W2215535790","https://openalex.org/W2222290303","https://openalex.org/W2237475067","https://openalex.org/W2288447626","https://openalex.org/W2334832052","https://openalex.org/W2399261310","https://openalex.org/W2501338590","https://openalex.org/W2529114944","https://openalex.org/W2562181574","https://openalex.org/W2593506275","https://openalex.org/W2734724639","https://openalex.org/W2741982109","https://openalex.org/W2771229928","https://openalex.org/W2790325052","https://openalex.org/W2791409258","https://openalex.org/W2802251199","https://openalex.org/W2810423511","https://openalex.org/W2907987213","https://openalex.org/W2908320623","https://openalex.org/W2913884646","https://openalex.org/W2914711689","https://openalex.org/W2915824064","https://openalex.org/W2936295302","https://openalex.org/W2940783197","https://openalex.org/W2949027215","https://openalex.org/W2963543751","https://openalex.org/W2966600595","https://openalex.org/W2967930270","https://openalex.org/W2978687867","https://openalex.org/W2980651856","https://openalex.org/W2984811115","https://openalex.org/W2992666626","https://openalex.org/W2993862932","https://openalex.org/W3000479870","https://openalex.org/W3003361050","https://openalex.org/W3005953879","https://openalex.org/W3006028518","https://openalex.org/W3012883032","https://openalex.org/W3035157797","https://openalex.org/W3049394606","https://openalex.org/W3084528742","https://openalex.org/W3086788791","https://openalex.org/W3119612691","https://openalex.org/W3154897461","https://openalex.org/W3160163020","https://openalex.org/W3160407865","https://openalex.org/W3164612879","https://openalex.org/W3178703016","https://openalex.org/W3190321126","https://openalex.org/W3195739405","https://openalex.org/W3196916730","https://openalex.org/W3201276384","https://openalex.org/W3201482376","https://openalex.org/W3204693560","https://openalex.org/W3206340295","https://openalex.org/W3206948891","https://openalex.org/W3209760524","https://openalex.org/W4205592486","https://openalex.org/W4280552835","https://openalex.org/W4281295065","https://openalex.org/W4283804489","https://openalex.org/W4287832822","https://openalex.org/W4293018115","https://openalex.org/W4315619045","https://openalex.org/W4315754561","https://openalex.org/W4318923555","https://openalex.org/W4322770791","https://openalex.org/W4367693449","https://openalex.org/W4372331165","https://openalex.org/W4378072505","https://openalex.org/W4381681857","https://openalex.org/W4382930114","https://openalex.org/W4383066372","https://openalex.org/W4383093105","https://openalex.org/W4385237448","https://openalex.org/W4385503492","https://openalex.org/W4385544840","https://openalex.org/W4385879911","https://openalex.org/W4386529182","https://openalex.org/W4386916169","https://openalex.org/W4388103540","https://openalex.org/W4390933442","https://openalex.org/W4391377569","https://openalex.org/W4391592880","https://openalex.org/W4391744602","https://openalex.org/W4391799523","https://openalex.org/W4392799318","https://openalex.org/W4392970898","https://openalex.org/W4396686162","https://openalex.org/W4399395069","https://openalex.org/W4399439504","https://openalex.org/W4399461049","https://openalex.org/W4399500327","https://openalex.org/W4400194169","https://openalex.org/W4400521208","https://openalex.org/W4402248153","https://openalex.org/W4403544061","https://openalex.org/W4404943412","https://openalex.org/W4405356785","https://openalex.org/W4406120337","https://openalex.org/W4409963211","https://openalex.org/W4410098756","https://openalex.org/W4411620315","https://openalex.org/W4412418462","https://openalex.org/W4412583876","https://openalex.org/W4413117974","https://openalex.org/W4413396401","https://openalex.org/W4413434186","https://openalex.org/W4414123068","https://openalex.org/W4414917129","https://openalex.org/W4415566191","https://openalex.org/W4415677280","https://openalex.org/W4415721085","https://openalex.org/W4415825712","https://openalex.org/W4415912252","https://openalex.org/W4415951323","https://openalex.org/W4416083516","https://openalex.org/W4416114828","https://openalex.org/W4416268070","https://openalex.org/W4417121419","https://openalex.org/W4417320155","https://openalex.org/W4417406154","https://openalex.org/W4417454191"],"related_works":["https://openalex.org/W7204863938","https://openalex.org/W4408204932","https://openalex.org/W7117542095","https://openalex.org/W7163126039","https://openalex.org/W7214084102","https://openalex.org/W4405356785","https://openalex.org/W4411015427","https://openalex.org/W7204796971","https://openalex.org/W7204496486","https://openalex.org/W7204765228"],"abstract_inverted_index":{"Metabolic":[0],"dysfunction-associated":[1,105],"steatotic":[2],"liver":[3],"disease":[4,63],"(MASLD)":[5],"is":[6,71],"increasing":[7],"in":[8],"prevalence":[9],"worldwide.":[10],"Pathogenesis":[11],"of":[12,42,51,74,91,103,126],"MASLD":[13,46,81],"has":[14],"been":[15,35],"considerably":[16],"heterogenous.":[17],"Increased":[18],"hepatic":[19,84],"de":[20],"novo":[21],"lipogenesis,":[22],"adipose":[23],"tissue":[24],"dysfunction,":[25],"genetic":[26],"predisposition,":[27],"epigenetic":[28],"mechanism,":[29],"and":[30,40,87,93,96,112,128],"other":[31],"related":[32],"factors":[33],"have":[34],"associated":[36],"with":[37,45,107],"the":[38,72,77,89,101,124,140],"development":[39],"progression":[41,90],"MASLD.":[43],"Patients":[44],"are":[47,98,115],"at":[48],"high":[49],"risk":[50],"not":[52],"only":[53],"adverse":[54],"liver-related":[55],"outcomes,":[56],"including":[57,64],"hepatocellular":[58],"carcinoma,":[59],"but":[60],"also":[61,139],"cardiometabolic":[62],"type":[65],"2":[66],"diabetes":[67],"mellitus.":[68],"Weight":[69],"loss":[70],"cornerstone":[73],"therapy":[75],"among":[76],"various":[78],"treatments":[79],"for":[80,100],"to":[82,109,123,134],"decrease":[83],"fat":[85],"accumulation":[86],"delay":[88],"inflammation":[92],"fibrosis.":[94],"Resmetirom":[95],"semaglutide":[97],"approved":[99],"treatment":[102],"metabolic":[104],"steatohepatitis":[106],"moderate":[108],"advanced":[110],"fibrosis,":[111],"many":[113],"drugs":[114],"under":[116],"investigation.":[117],"Careful":[118],"attention":[119],"should":[120,131],"be":[121,132],"paid":[122],"screening":[125],"MASLD,":[127],"concerted":[129],"efforts":[130],"made":[133],"manage":[135],"it":[136],"appropriately.":[137],"See":[138],"graphical":[141],"abstract(Fig.":[142],"1).":[143]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-09-23T00:00:00"}
