{"id":"https://openalex.org/W7214003604","doi":"https://doi.org/10.4269/ajtmh.26-0091","title":"Genetic Relatedness of Cambodian Plasmodium falciparum Isolates Was Associated with Geography and Occupation","display_name":"Genetic Relatedness of Cambodian Plasmodium falciparum Isolates Was Associated with Geography and Occupation","publication_year":2026,"publication_date":"2026-09-22","ids":{"openalex":"https://openalex.org/W7214003604","doi":"https://doi.org/10.4269/ajtmh.26-0091","pmid":"https://pubmed.ncbi.nlm.nih.gov/41674609","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12889777"},"language":"en","primary_location":{"id":"doi:10.4269/ajtmh.26-0091","doi":"https://doi.org/10.4269/ajtmh.26-0091","is_oa":false,"landing_page_url":"https://doi.org/10.4269/ajtmh.26-0091","pdf_url":null,"source":{"id":"https://openalex.org/S100045985","display_name":"American Journal of Tropical Medicine and Hygiene","issn_l":"0002-9637","issn":["0002-9637","1476-1645"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315658","host_organization_name":"American Society of Tropical Medicine and Hygiene","host_organization_lineage":["https://openalex.org/P4310315658"],"host_organization_lineage_names":["American Society of Tropical Medicine and Hygiene"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Tropical Medicine and Hygiene","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.medrxiv.org/content/medrxiv/early/2026/02/06/2026.01.29.26344731.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5159322554","display_name":"Emma Rowley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emma Rowley","raw_affiliation_strings":["Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA;","institution_ids":["https://openalex.org/I126744593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5125443070","display_name":"Bing Guo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bing Guo","raw_affiliation_strings":["Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA;","Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA;","institution_ids":["https://openalex.org/I126744593"]},{"raw_affiliation_string":"Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA;","institution_ids":["https://openalex.org/I126744593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086466760","display_name":"Mariusz Wojnarski","orcid":"https://orcid.org/0000-0001-6710-6385","observed_orcids":["https://orcid.org/0000-0001-6710-6385"]},"institutions":[{"id":"https://openalex.org/I4210112607","display_name":"Armed Forces Research Institute of Medical Science","ror":"https://ror.org/023swxh49","country_code":"TH","type":"nonprofit","lineage":["https://openalex.org/I2801080794","https://openalex.org/I4210112607","https://openalex.org/I4387156032"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Mariusz Wojnarski","raw_affiliation_strings":["Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;","institution_ids":["https://openalex.org/I4210112607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041986910","display_name":"Michele Spring","orcid":"https://orcid.org/0000-0002-2921-9677","observed_orcids":["https://orcid.org/0000-0002-2921-9677"]},"institutions":[{"id":"https://openalex.org/I4210112607","display_name":"Armed Forces Research Institute of Medical Science","ror":"https://ror.org/023swxh49","country_code":"TH","type":"nonprofit","lineage":["https://openalex.org/I2801080794","https://openalex.org/I4210112607","https://openalex.org/I4387156032"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Michele D. Spring","raw_affiliation_strings":["Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;","institution_ids":["https://openalex.org/I4210112607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050474167","display_name":"Sabaithip Sriwichai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210112607","display_name":"Armed Forces Research Institute of Medical Science","ror":"https://ror.org/023swxh49","country_code":"TH","type":"nonprofit","lineage":["https://openalex.org/I2801080794","https://openalex.org/I4210112607","https://openalex.org/I4387156032"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Sabaithip Sriwichai","raw_affiliation_strings":["Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;","institution_ids":["https://openalex.org/I4210112607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021636488","display_name":"Brian A. Vesely","orcid":"https://orcid.org/0009-0009-5708-5782","observed_orcids":["https://orcid.org/0009-0009-5708-5782"]},"institutions":[{"id":"https://openalex.org/I4210112607","display_name":"Armed Forces Research Institute of Medical Science","ror":"https://ror.org/023swxh49","country_code":"TH","type":"nonprofit","lineage":["https://openalex.org/I2801080794","https://openalex.org/I4210112607","https://openalex.org/I4387156032"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Brian A. Vesely","raw_affiliation_strings":["Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;","institution_ids":["https://openalex.org/I4210112607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123816676","display_name":"Joana Silva","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joana C. Silva","raw_affiliation_strings":["Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA;","institution_ids":["https://openalex.org/I126744593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109094608","display_name":"Norman C. Waters","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210112607","display_name":"Armed Forces Research Institute of Medical Science","ror":"https://ror.org/023swxh49","country_code":"TH","type":"nonprofit","lineage":["https://openalex.org/I2801080794","https://openalex.org/I4210112607","https://openalex.org/I4387156032"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Norman C. Waters","raw_affiliation_strings":["Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;","institution_ids":["https://openalex.org/I4210112607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040049599","display_name":"Sasikanya Thaloengsok","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210112607","display_name":"Armed Forces Research Institute of Medical Science","ror":"https://ror.org/023swxh49","country_code":"TH","type":"nonprofit","lineage":["https://openalex.org/I2801080794","https://openalex.org/I4210112607","https://openalex.org/I4387156032"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Sasikanya Thaloengsok","raw_affiliation_strings":["Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;","institution_ids":["https://openalex.org/I4210112607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002207161","display_name":"Piyaporn Saingam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210112607","display_name":"Armed Forces Research Institute of Medical Science","ror":"https://ror.org/023swxh49","country_code":"TH","type":"nonprofit","lineage":["https://openalex.org/I2801080794","https://openalex.org/I4210112607","https://openalex.org/I4387156032"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Piyaporn Sai-ngam","raw_affiliation_strings":["Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;","institution_ids":["https://openalex.org/I4210112607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089210177","display_name":"Chaiyaporn Chaisatit","orcid":"https://orcid.org/0009-0002-5033-0182","observed_orcids":["https://orcid.org/0009-0002-5033-0182"]},"institutions":[{"id":"https://openalex.org/I4210112607","display_name":"Armed Forces Research Institute of Medical Science","ror":"https://ror.org/023swxh49","country_code":"TH","type":"nonprofit","lineage":["https://openalex.org/I2801080794","https://openalex.org/I4210112607","https://openalex.org/I4387156032"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Chaiyaporn Chaisatit","raw_affiliation_strings":["Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;","institution_ids":["https://openalex.org/I4210112607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043685477","display_name":"Paphavee Lertsethtakarn","orcid":"https://orcid.org/0000-0003-2993-9794","observed_orcids":["https://orcid.org/0000-0003-2993-9794"]},"institutions":[{"id":"https://openalex.org/I4210112607","display_name":"Armed Forces Research Institute of Medical Science","ror":"https://ror.org/023swxh49","country_code":"TH","type":"nonprofit","lineage":["https://openalex.org/I2801080794","https://openalex.org/I4210112607","https://openalex.org/I4387156032"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Paphavee Lertsethtakarn","raw_affiliation_strings":["Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;","institution_ids":["https://openalex.org/I4210112607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086769089","display_name":"Somethy Sok","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Somethy Sok","raw_affiliation_strings":["Royal Cambodian Armed Forces, Phnom Penh, Cambodia;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Royal Cambodian Armed Forces, Phnom Penh, Cambodia;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002648701","display_name":"Satharath Prom","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Prom Satharath","raw_affiliation_strings":["Royal Cambodian Armed Forces, Phnom Penh, Cambodia;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Royal Cambodian Armed Forces, Phnom Penh, Cambodia;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089946703","display_name":"Sidhartha Chaudhury","orcid":"https://orcid.org/0000-0001-9513-6688","observed_orcids":["https://orcid.org/0000-0001-9513-6688"]},"institutions":[{"id":"https://openalex.org/I4210112607","display_name":"Armed Forces Research Institute of Medical Science","ror":"https://ror.org/023swxh49","country_code":"TH","type":"nonprofit","lineage":["https://openalex.org/I2801080794","https://openalex.org/I4210112607","https://openalex.org/I4387156032"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Sidhartha Chaudhury","raw_affiliation_strings":["Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Walter-Reed Army Institute of Research Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;","institution_ids":["https://openalex.org/I4210112607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013688884","display_name":"Chanthap Lon","orcid":"https://orcid.org/0000-0003-4901-5003","observed_orcids":["https://orcid.org/0000-0003-4901-5003"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chanthap Lon","raw_affiliation_strings":["International Center of Excellence in Research, National Institute of Allergy and Infectious Disease, National Institutes of Health, Phnom Penh, Cambodia;","Laboratory of Malaria and Vector Research, National Institutes of Health, Bethesda, Maryland, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Center of Excellence in Research, National Institute of Allergy and Infectious Disease, National Institutes of Health, Phnom Penh, Cambodia;","institution_ids":[]},{"raw_affiliation_string":"Laboratory of Malaria and Vector Research, National Institutes of Health, Bethesda, Maryland, USA;","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063685504","display_name":"Dysoley Lek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799511387","display_name":"Cambodia National Malaria Center","ror":"https://ror.org/03bznzd25","country_code":"KH","type":"government","lineage":["https://openalex.org/I2799511387"]}],"countries":["KH"],"is_corresponding":false,"raw_author_name":"Dysoley Lek","raw_affiliation_strings":["National Center for Parasitology, Entomology, and Malaria Control, Village Trapangsvay, Sanakat Phnom Penh, Cambodia;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Center for Parasitology, Entomology, and Malaria Control, Village Trapangsvay, Sanakat Phnom Penh, Cambodia;","institution_ids":["https://openalex.org/I2799511387"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067163783","display_name":"David Saunders","orcid":"https://orcid.org/0000-0003-0946-1164","observed_orcids":["https://orcid.org/0000-0003-0946-1164"]},"institutions":[{"id":"https://openalex.org/I2801122164","display_name":"United States Army Medical Research Institute of Infectious Diseases","ror":"https://ror.org/01pveve47","country_code":"US","type":"facility","lineage":["https://openalex.org/I106965489","https://openalex.org/I1304082316","https://openalex.org/I1330347796","https://openalex.org/I2801122164","https://openalex.org/I2802581893"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Saunders","raw_affiliation_strings":["US Army Medical Research Institute of Infectious Diseases, Ft. Detrick, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"US Army Medical Research Institute of Infectious Diseases, Ft. Detrick, Maryland, USA","institution_ids":["https://openalex.org/I2801122164"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103172233","display_name":"Timothy D. O\u2019Connor","orcid":"https://orcid.org/0000-0002-0276-1896","observed_orcids":["https://orcid.org/0000-0002-0276-1896","https://orcid.org/0000-0001-5413-6526"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy D. O\u2019Connor","raw_affiliation_strings":["Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA;","institution_ids":["https://openalex.org/I126744593"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011546643","display_name":"Shannon Takala\u2010Harrison","orcid":"https://orcid.org/0000-0003-4674-8500","observed_orcids":["https://orcid.org/0000-0003-4674-8500"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shannon Takala-Harrison","raw_affiliation_strings":["Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA;","institution_ids":["https://openalex.org/I126744593"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":5.0263,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.95978229,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"115","issue":"5","first_page":"1027","last_page":"1035"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10012","display_name":"Genetic diversity and population structure","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12178","display_name":"Bird parasitology and diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/plasmodium-falciparum","display_name":"Plasmodium falciparum","score":0.9990000128746033},{"id":"https://openalex.org/keywords/genetic-relationships","display_name":"genetic relatedness","score":0.7559999823570251},{"id":"https://openalex.org/keywords/identity-by-descent","display_name":"identity by descent","score":0.8410000205039978},{"id":"https://openalex.org/keywords/malaria-transmission","display_name":"malaria transmission","score":0.6779999732971191},{"id":"https://openalex.org/keywords/malaria-elimination","display_name":"malaria elimination","score":0.6420000195503235},{"id":"https://openalex.org/keywords/drug-resistance","display_name":"drug resistance","score":0.4690000116825104},{"id":"https://openalex.org/keywords/k13-mutations","display_name":"K13 mutations","score":0.8999999761581421},{"id":"https://openalex.org/keywords/occupation","display_name":"occupation","score":0.593999981880188},{"id":"https://openalex.org/keywords/farmers","display_name":"farmers","score":0.6629999876022339},{"id":"https://openalex.org/keywords/military-personnel","display_name":"military personnel","score":0.9929999709129333},{"id":"https://openalex.org/keywords/regional-variation","display_name":"regional variation","score":0.4819999933242798},{"id":"https://openalex.org/keywords/micro-epidemiology","display_name":"micro-epidemiology","score":0.8339999914169312},{"id":"https://openalex.org/keywords/cambodia","display_name":"Cambodia","score":0.43799999356269836}],"concepts":[{"id":"https://openalex.org/C2778371730","wikidata":"https://www.wikidata.org/wiki/Q311383","display_name":"Plasmodium falciparum","level":3,"score":0.7455999851226807},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7261000275611877},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5422000288963318},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.47380000352859497},{"id":"https://openalex.org/C24432333","wikidata":"https://www.wikidata.org/wiki/Q2068526","display_name":"Whole genome sequencing","level":4,"score":0.40400001406669617},{"id":"https://openalex.org/C143095724","wikidata":"https://www.wikidata.org/wiki/Q515895","display_name":"Odds","level":3,"score":0.38839998841285706},{"id":"https://openalex.org/C97669555","wikidata":"https://www.wikidata.org/wiki/Q4118435","display_name":"Molecular epidemiology","level":4,"score":0.38679999113082886},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.3578999936580658},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.3336000144481659},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.3330000042915344},{"id":"https://openalex.org/C177860879","wikidata":"https://www.wikidata.org/wiki/Q5532897","display_name":"Genetic epidemiology","level":3,"score":0.329800009727478},{"id":"https://openalex.org/C193252679","wikidata":"https://www.wikidata.org/wiki/Q242125","display_name":"Phylogenetic tree","level":3,"score":0.3294000029563904},{"id":"https://openalex.org/C164866538","wikidata":"https://www.wikidata.org/wiki/Q367351","display_name":"Cluster (spacecraft)","level":2,"score":0.31769999861717224},{"id":"https://openalex.org/C761482","wikidata":"https://www.wikidata.org/wiki/Q118093","display_name":"Transmission (telecommunications)","level":2,"score":0.31700000166893005},{"id":"https://openalex.org/C138592617","wikidata":"https://www.wikidata.org/wiki/Q748695","display_name":"Genetic distance","level":4,"score":0.2939999997615814},{"id":"https://openalex.org/C2776817793","wikidata":"https://www.wikidata.org/wiki/Q6553369","display_name":"Lineage (genetic)","level":3,"score":0.29170000553131104},{"id":"https://openalex.org/C68873052","wikidata":"https://www.wikidata.org/wiki/Q349856","display_name":"Genetic variation","level":3,"score":0.288100004196167},{"id":"https://openalex.org/C184898388","wikidata":"https://www.wikidata.org/wiki/Q1435712","display_name":"Pairwise comparison","level":2,"score":0.266400009393692},{"id":"https://openalex.org/C90132467","wikidata":"https://www.wikidata.org/wiki/Q171184","display_name":"Phylogenetics","level":3,"score":0.26030001044273376},{"id":"https://openalex.org/C64618202","wikidata":"https://www.wikidata.org/wiki/Q3733697","display_name":"Genetic heterogeneity","level":4,"score":0.2590999901294708},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.25519999861717224},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.25099998712539673}],"mesh":[],"locations_count":7,"locations":[{"id":"doi:10.4269/ajtmh.26-0091","doi":"https://doi.org/10.4269/ajtmh.26-0091","is_oa":false,"landing_page_url":"https://doi.org/10.4269/ajtmh.26-0091","pdf_url":null,"source":{"id":"https://openalex.org/S100045985","display_name":"American Journal of Tropical Medicine and Hygiene","issn_l":"0002-9637","issn":["0002-9637","1476-1645"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315658","host_organization_name":"American Society of Tropical Medicine and Hygiene","host_organization_lineage":["https://openalex.org/P4310315658"],"host_organization_lineage_names":["American Society of Tropical Medicine and Hygiene"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Tropical Medicine and Hygiene","raw_type":"journal-article"},{"id":"doi:10.64898/2026.01.29.26344731","doi":"https://doi.org/10.64898/2026.01.29.26344731","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.01.29.26344731","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/02/06/2026.01.29.26344731.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},{"id":"pmid:41674609","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41674609","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"medRxiv : the preprint server for health sciences","raw_type":"Journal Article"},{"id":"pmid:42772274","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42772274","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of tropical medicine and hygiene","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12889777","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12889777/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"medRxiv","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:13615265","doi":null,"is_oa":true,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42772274/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Trop Med Hyg","raw_type":"Text"},{"id":"pmh:oai:europepmc.org:11697225","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12889777","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.64898/2026.01.29.26344731","doi":"https://doi.org/10.64898/2026.01.29.26344731","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.01.29.26344731","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/02/06/2026.01.29.26344731.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8999999761581421}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2660210567","display_name":"Genomic and geospatial analyses of malaria parasite migration to inform elimination","funder_award_id":"5r01ai145852-05","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000306425","display_name":null,"funder_award_id":"1R01AI145852","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000898698","display_name":"Genomic surveillance for artemisinin resistance in Africa: moving beyond a candidate gene approach","funder_award_id":"1r01ai183599-01a1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7214003604.pdf","grobid_xml":"https://content.openalex.org/works/W7214003604.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W2000623019","https://openalex.org/W2017171726","https://openalex.org/W2044824227","https://openalex.org/W2081078606","https://openalex.org/W2110423774","https://openalex.org/W2124209874","https://openalex.org/W2124634096","https://openalex.org/W2148874079","https://openalex.org/W2162928486","https://openalex.org/W2164998314","https://openalex.org/W2467259677","https://openalex.org/W2577537660","https://openalex.org/W2584480708","https://openalex.org/W2754251247","https://openalex.org/W2765137312","https://openalex.org/W2766160192","https://openalex.org/W2766207587","https://openalex.org/W2789297352","https://openalex.org/W2803023244","https://openalex.org/W2886706562","https://openalex.org/W2896118189","https://openalex.org/W2924530200","https://openalex.org/W2938020510","https://openalex.org/W2949771812","https://openalex.org/W2951407752","https://openalex.org/W2951479370","https://openalex.org/W2952113787","https://openalex.org/W2959086676","https://openalex.org/W2963818102","https://openalex.org/W2968619018","https://openalex.org/W2972252655","https://openalex.org/W2986984498","https://openalex.org/W3103691166","https://openalex.org/W3127977203","https://openalex.org/W3129677181","https://openalex.org/W3131055609","https://openalex.org/W4200218612","https://openalex.org/W4225611682","https://openalex.org/W4312060003","https://openalex.org/W4382022940","https://openalex.org/W4391719339","https://openalex.org/W4392984232","https://openalex.org/W4397014312","https://openalex.org/W4399601891","https://openalex.org/W4407849632","https://openalex.org/W4417260247","https://openalex.org/W6931415398"],"related_works":["https://openalex.org/W7128232435","https://openalex.org/W3016206838","https://openalex.org/W2410795767","https://openalex.org/W2766207587","https://openalex.org/W3100046433","https://openalex.org/W6958578014","https://openalex.org/W4312060003","https://openalex.org/W2963818102","https://openalex.org/W4402742251","https://openalex.org/W2735848561"],"abstract_inverted_index":{"Background:":[0],"elimination,":[1],"but":[2],"targeted":[3],"interventions":[4,222],"are":[5],"needed":[6],"to":[7,74,211,223],"prevent":[8],"resurgence.":[9],"Identity-by-descent":[10],"(IBD)-based":[11],"methods":[12],"offer":[13],"insight":[14],"into":[15],"parasite":[16],"relatedness":[17,58,95,164,193,203,206],"and":[18,27,33,59,67,81,147,152,185,219],"transmission":[19,217],"dynamics.":[20],"Methods:":[21],"isolates":[22,36,97,109],"collected":[23],"from":[24,98,102,110,156,169],"military":[25],"personnel":[26],"farmers":[28,170],"in":[29,192,201],"Cambodia":[30],"between":[31,52,57,194],"2014":[32],"2016.":[34],"All":[35],"underwent":[37],"whole":[38],"genome":[39,49,120],"sequencing.":[40],"Relatedness":[41],"was":[42,72,90],"defined":[43],"as":[44],"the":[45,48,197],"proportion":[46],"of":[47,77,118,126,162,181,187,199],"shared":[50,115],"IBD":[51,88,121,175],"isolates.":[53],"We":[54],"evaluated":[55],"associations":[56],"epidemiologic":[60],"factors,":[61],"including":[62],"occupation,":[63,141],"location,":[64],"time,":[65],"age,":[66],"sex.":[68],"Infomap":[69],"community":[70],"detection":[71],"used":[73],"identify":[75],"clusters":[76,135],"highly":[78],"related":[79,134],"parasites":[80],"their":[82,119],"association":[83],"with":[84,93,112,140],"covariates.":[85],"Results:":[86],"Mean":[87],"sharing":[89,176],"high":[91,163],"(40%),":[92],"greater":[94],"among":[96,207],"Oddar":[99,107],"Meanchey":[100],"than":[101,122,167],"Kratie":[103],"province":[104],"(p<2.2e-16).":[105],"Within":[106],"Meanchey,":[108],"individuals":[111],"different":[113],"occupations":[114],"7.2%":[116],"less":[117],"farmer":[123,212],"pairs":[124,158,168,209,213],"(probability":[125],"direction":[127],"(pd)=99.9),":[128],"after":[129],"adjusting":[130],"for":[131],"age.":[132],"Highly":[133],"(>90%":[136,165],"IBD)":[137,166],"were":[138],"associated":[139],"K13":[142],"mutation":[143,149],"(C580Y":[144],"vs.":[145],"R539T),":[146],"PfCRT":[148],"(p=0.0025,":[150],"0.0001,":[151,153],"respectively).":[154],"Isolates":[155],"mixed-occupation":[157,208],"had":[159],"lower":[160],"odds":[161],"(pd=0.958).":[171],"Conclusions:":[172],"High":[173],"overall":[174],"may":[177],"reflect":[178],"a":[179],"combination":[180],"recent":[182],"elimination":[183],"efforts":[184],"expansion":[186],"drug-resistant":[188],"lineages.":[189],"Substantial":[190],"differences":[191],"provinces":[195],"underscore":[196],"role":[198],"geography":[200],"shaping":[202],"patterns.":[204],"Lower":[205],"compared":[210],"suggests":[214],"potential":[215],"occupation-specific":[216],"sources":[218],"supports":[220],"tailoring":[221],"local":[224],"micro-epidemiologic":[225],"factors.":[226]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-09-23T00:00:00"}