{"id":"https://openalex.org/W7213974506","doi":"https://doi.org/10.64898/2026.09.20.752968","title":"Human body-site-stratified fungal genomic catalogs enhancing human mycobiome analysis","display_name":"Human body-site-stratified fungal genomic catalogs enhancing human mycobiome analysis","publication_year":2026,"publication_date":"2026-09-21","ids":{"openalex":"https://openalex.org/W7213974506","doi":"https://doi.org/10.64898/2026.09.20.752968"},"language":"en","primary_location":{"id":"doi:10.64898/2026.09.20.752968","doi":"https://doi.org/10.64898/2026.09.20.752968","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.20.752968","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/09/21/2026.09.20.752968.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2026/09/21/2026.09.20.752968.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5152432391","display_name":"Sehun Ahn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sehun Ahn","raw_affiliation_strings":["Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea","institution_ids":["https://openalex.org/I193775966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013830080","display_name":"Jungyeon Kim","orcid":"https://orcid.org/0000-0003-1193-0919","observed_orcids":["https://orcid.org/0000-0003-1193-0919","https://orcid.org/0009-0002-3453-6834"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jungyeon Kim","raw_affiliation_strings":["Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea","institution_ids":["https://openalex.org/I193775966"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035867403","display_name":"Insuk Lee","orcid":"https://orcid.org/0000-0003-3146-6180","observed_orcids":["https://orcid.org/0000-0003-3146-6180"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Insuk Lee","raw_affiliation_strings":["DECODEBIOME Co., Ltd. Incheon 21983, Republic of Korea","Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0003-3146-6180","affiliations":[{"raw_affiliation_string":"DECODEBIOME Co., Ltd. Incheon 21983, Republic of Korea","institution_ids":[]},{"raw_affiliation_string":"Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea","institution_ids":["https://openalex.org/I193775966"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5035867403"],"corresponding_institution_ids":["https://openalex.org/I193775966"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.5932999849319458,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.5932999849319458,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.07540000230073929,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.058800000697374344,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fungal-taxonomy","display_name":"fungal taxonomy","score":0.6880000233650208},{"id":"https://openalex.org/keywords/gut-mycobiome","display_name":"gut mycobiome","score":0.9639999866485596},{"id":"https://openalex.org/keywords/oral-mycobiome","display_name":"oral mycobiome","score":0.9750000238418579},{"id":"https://openalex.org/keywords/skin-mycobiome","display_name":"skin mycobiome","score":0.9919999837875366}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5978999733924866},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5303000211715698},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.527899980545044},{"id":"https://openalex.org/C187191949","wikidata":"https://www.wikidata.org/wiki/Q1138496","display_name":"Profiling (computer programming)","level":2,"score":0.44519999623298645},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.35910001397132874},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.31189998984336853},{"id":"https://openalex.org/C19843653","wikidata":"https://www.wikidata.org/wiki/Q213907","display_name":"Model organism","level":3,"score":0.29989999532699585},{"id":"https://openalex.org/C81669768","wikidata":"https://www.wikidata.org/wiki/Q2359161","display_name":"Precision and recall","level":2,"score":0.288100004196167},{"id":"https://openalex.org/C197077220","wikidata":"https://www.wikidata.org/wiki/Q720988","display_name":"Human genome","level":4,"score":0.2842000126838684},{"id":"https://openalex.org/C64502627","wikidata":"https://www.wikidata.org/wiki/Q170065","display_name":"Pathogenicity","level":2,"score":0.27619999647140503},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.27129998803138733},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2696000039577484},{"id":"https://openalex.org/C2986629439","wikidata":"https://www.wikidata.org/wiki/Q9635","display_name":"Oral cavity","level":2,"score":0.26930001378059387},{"id":"https://openalex.org/C24527192","wikidata":"https://www.wikidata.org/wiki/Q17149729","display_name":"Human pathogen","level":3,"score":0.2662000060081482},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.2549999952316284}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.09.20.752968","doi":"https://doi.org/10.64898/2026.09.20.752968","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.20.752968","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/09/21/2026.09.20.752968.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.64898/2026.09.20.752968","doi":"https://doi.org/10.64898/2026.09.20.752968","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.20.752968","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/09/21/2026.09.20.752968.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1371859516","display_name":null,"funder_award_id":"RS-2025-18362970","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G5334485699","display_name":null,"funder_award_id":"RS-2025\u201318362970","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"}],"funders":[{"id":"https://openalex.org/F4320320671","display_name":"National Research Foundation","ror":"https://ror.org/05s0g1g46"},{"id":"https://openalex.org/F4320322120","display_name":"National Research Foundation of Korea","ror":"https://ror.org/013aysd81"},{"id":"https://openalex.org/F4320328359","display_name":"Ministry of Science and ICT, South Korea","ror":"https://ror.org/01wpjm123"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7213974506.pdf","grobid_xml":"https://content.openalex.org/works/W7213974506.grobid-xml"},"referenced_works_count":22,"referenced_works":["https://openalex.org/W1005007408","https://openalex.org/W2074335138","https://openalex.org/W2108234281","https://openalex.org/W2113552312","https://openalex.org/W2131271579","https://openalex.org/W2170486072","https://openalex.org/W2170551349","https://openalex.org/W2345658906","https://openalex.org/W2919677651","https://openalex.org/W2950883119","https://openalex.org/W2953263404","https://openalex.org/W2990618091","https://openalex.org/W3083864964","https://openalex.org/W3133550758","https://openalex.org/W4200432348","https://openalex.org/W4220999759","https://openalex.org/W4285011536","https://openalex.org/W4389738223","https://openalex.org/W4399884443","https://openalex.org/W4408170833","https://openalex.org/W4415664752","https://openalex.org/W4416983863"],"related_works":["https://openalex.org/W4417117336","https://openalex.org/W2950027438","https://openalex.org/W4285011536","https://openalex.org/W6946309873","https://openalex.org/W6939841586","https://openalex.org/W4401511568","https://openalex.org/W4398167276","https://openalex.org/W6902228420","https://openalex.org/W2121774335","https://openalex.org/W3012861870"],"abstract_inverted_index":{"Abstract":[0],"Current":[1],"human":[2],"mycobiome":[3],"profiling":[4],"relies":[5],"largely":[6],"on":[7],"marker-based":[8],"methods":[9],"with":[10],"limited":[11],"sensitivity,":[12],"whereas":[13],"genome-based":[14],"approaches":[15],"require":[16],"computationally":[17],"intensive":[18],"alignment":[19],"against":[20],"broad":[21],"fungal":[22,30],"references.":[23],"Here,":[24],"we":[25,51],"present":[26],"MycobiomeDB,":[27],"a":[28],"unified":[29],"genome":[31],"catalog,":[32],"and":[33,43,59],"derive":[34],"body-site-specific":[35],"catalogs":[36],"for":[37],"the":[38],"gut,":[39],"oral":[40],"cavity,":[41],"skin,":[42],"vagina":[44],"through":[45],"metagenome-guided":[46],"stratification.":[47],"Using":[48],"these":[49],"catalogs,":[50],"developed":[52],"site-specific":[53],"MycoProfilers":[54],"that":[55],"improved":[56],"taxonomic":[57],"recall":[58],"better":[60],"distinguished":[61],"disease-associated":[62],"mycobiomes":[63],"from":[64],"healthy":[65],"controls":[66],"than":[67],"existing":[68],"methods.":[69]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-09-22T00:00:00"}