{"id":"https://openalex.org/W7213880274","doi":"https://doi.org/10.3389/fneur.2026.1931533","title":"Hypothalamic subregional volume in relation to VSS-C total symptom burden in women with migraine: an exploratory cross-sectional MRI study","display_name":"Hypothalamic subregional volume in relation to VSS-C total symptom burden in women with migraine: an exploratory cross-sectional MRI study","publication_year":2026,"publication_date":"2026-09-21","ids":{"openalex":"https://openalex.org/W7213880274","doi":"https://doi.org/10.3389/fneur.2026.1931533","pmid":"https://pubmed.ncbi.nlm.nih.gov/42834909","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13634837"},"language":"en","primary_location":{"id":"doi:10.3389/fneur.2026.1931533","doi":"https://doi.org/10.3389/fneur.2026.1931533","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fneur.2026.1931533","pdf_url":"https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2026.1931533/pdf","source":{"id":"https://openalex.org/S96975567","display_name":"Frontiers in Neurology","issn_l":"1664-2295","issn":["1664-2295"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neurology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2026.1931533/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5136907171","display_name":"Linyi Che","orcid":"https://orcid.org/0009-0006-2549-8943","observed_orcids":["https://orcid.org/0009-0006-2549-8943"]},"institutions":[{"id":"https://openalex.org/I4210129459","display_name":"The Affiliated Yongchuan Hospital of Chongqing Medical University","ror":"https://ror.org/033vnzz93","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210129459"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Linyi Che","raw_affiliation_strings":["Department of Neurology, The First Affiliated Hospital of Chongqing Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, The First Affiliated Hospital of Chongqing Medical University","institution_ids":["https://openalex.org/I4210129459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5136972394","display_name":"Wanqun Hu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210149928","display_name":"Chongqing Jiulongpo People's Hospital","ror":"https://ror.org/057skcn66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210149928"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wanqun Hu","raw_affiliation_strings":["Department of Neurology, Chongqing Jiulongpo District Science City People's Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Chongqing Jiulongpo District Science City People's Hospital","institution_ids":["https://openalex.org/I4210149928"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024785057","display_name":"Xiaoping Fan","orcid":"https://orcid.org/0000-0003-0172-4070","observed_orcids":["https://orcid.org/0000-0003-0172-4070"]},"institutions":[{"id":"https://openalex.org/I4210129459","display_name":"The Affiliated Yongchuan Hospital of Chongqing Medical University","ror":"https://ror.org/033vnzz93","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210129459"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoping Fan","raw_affiliation_strings":["Phase I Clinical Research Center, The First Affiliated Hospital of Chongqing Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Phase I Clinical Research Center, The First Affiliated Hospital of Chongqing Medical University","institution_ids":["https://openalex.org/I4210129459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101260462","display_name":"Qinlian Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210129459","display_name":"The Affiliated Yongchuan Hospital of Chongqing Medical University","ror":"https://ror.org/033vnzz93","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210129459"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qinlian Huang","raw_affiliation_strings":["Department of Neurology, The First Affiliated Hospital of Chongqing Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, The First Affiliated Hospital of Chongqing Medical University","institution_ids":["https://openalex.org/I4210129459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5157242367","display_name":"Ruonan Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210129459","display_name":"The Affiliated Yongchuan Hospital of Chongqing Medical University","ror":"https://ror.org/033vnzz93","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210129459"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruonan Zhang","raw_affiliation_strings":["Department of Neurology, The First Affiliated Hospital of Chongqing Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, The First Affiliated Hospital of Chongqing Medical University","institution_ids":["https://openalex.org/I4210129459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5136931611","display_name":"Yuhui Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210129459","display_name":"The Affiliated Yongchuan Hospital of Chongqing Medical University","ror":"https://ror.org/033vnzz93","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210129459"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuhui Xu","raw_affiliation_strings":["Department of Neurology, The First Affiliated Hospital of Chongqing Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, The First Affiliated Hospital of Chongqing Medical University","institution_ids":["https://openalex.org/I4210129459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147393706","display_name":"Liang Dong","orcid":"https://orcid.org/0009-0003-2234-9457","observed_orcids":["https://orcid.org/0009-0003-2234-9457"]},"institutions":[{"id":"https://openalex.org/I4210129459","display_name":"The Affiliated Yongchuan Hospital of Chongqing Medical University","ror":"https://ror.org/033vnzz93","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210129459"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Liang Dong","raw_affiliation_strings":["Department of Neurology, The First Affiliated Hospital of Chongqing Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, The First Affiliated Hospital of Chongqing Medical University","institution_ids":["https://openalex.org/I4210129459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5152365335","display_name":"Li Jiang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210129459","display_name":"The Affiliated Yongchuan Hospital of Chongqing Medical University","ror":"https://ror.org/033vnzz93","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210129459"]},{"id":"https://openalex.org/I4210160019","display_name":"Chongqing Municipal Health Commission","ror":"https://ror.org/04ce5fg13","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210157972","https://openalex.org/I4210160019"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Li Jiang","raw_affiliation_strings":["Department of Rehabilitation Medicine, Key Laboratory of Physical Medicine and Precision Rehabilitation of Chongqing Municipal Health Commission, The First Affiliated Hospital of Chongqing Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rehabilitation Medicine, Key Laboratory of Physical Medicine and Precision Rehabilitation of Chongqing Municipal Health Commission, The First Affiliated Hospital of Chongqing Medical University","institution_ids":["https://openalex.org/I4210129459","https://openalex.org/I4210160019"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086081945","display_name":"Jiying Zhou","orcid":"https://orcid.org/0000-0003-3923-4683","observed_orcids":["https://orcid.org/0000-0003-3923-4683","https://orcid.org/0000-0001-6302-8332","https://orcid.org/0000-0002-0670-3589"]},"institutions":[{"id":"https://openalex.org/I4210129459","display_name":"The Affiliated Yongchuan Hospital of Chongqing Medical University","ror":"https://ror.org/033vnzz93","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210129459"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jiying Zhou","raw_affiliation_strings":["Department of Neurology, The First Affiliated Hospital of Chongqing Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, The First Affiliated Hospital of Chongqing Medical University","institution_ids":["https://openalex.org/I4210129459"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5086081945","https://openalex.org/A5147393706","https://openalex.org/A5152365335"],"corresponding_institution_ids":["https://openalex.org/I4210129459","https://openalex.org/I4210160019"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"17","issue":null,"first_page":"1931533","last_page":"1931533"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10498","display_name":"Migraine and Headache Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10498","display_name":"Migraine and Headache Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10542","display_name":"Vestibular and auditory disorders","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13397","display_name":"Hallucinations in medical conditions","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/migraine","display_name":"migraine","score":0.953000009059906},{"id":"https://openalex.org/keywords/hypothalamus","display_name":"hypothalamus","score":0.8529999852180481},{"id":"https://openalex.org/keywords/vertigo","display_name":"vertigo","score":0.7039999961853027},{"id":"https://openalex.org/keywords/dizziness","display_name":"dizziness","score":0.9279999732971191},{"id":"https://openalex.org/keywords/autonomic-symptoms","display_name":"autonomic symptoms","score":0.8730000257492065},{"id":"https://openalex.org/keywords/anxiety","display_name":"anxiety","score":0.8119999766349792},{"id":"https://openalex.org/keywords/symptom-burden","display_name":"symptom burden","score":0.7450000047683716},{"id":"https://openalex.org/keywords/women","display_name":"women","score":0.6100000143051147},{"id":"https://openalex.org/keywords/brain-structure","display_name":"brain structure","score":0.382999986410141},{"id":"https://openalex.org/keywords/vestibular-symptoms","display_name":"vestibular symptoms","score":0.6380000114440918}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7595000267028809},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.6351000070571899},{"id":"https://openalex.org/C119060515","wikidata":"https://www.wikidata.org/wiki/Q1916617","display_name":"Interquartile range","level":2,"score":0.46299999952316284},{"id":"https://openalex.org/C2779889316","wikidata":"https://www.wikidata.org/wiki/Q642836","display_name":"Neuroradiology","level":3,"score":0.4399999976158142},{"id":"https://openalex.org/C2778541695","wikidata":"https://www.wikidata.org/wiki/Q133823","display_name":"Migraine","level":2,"score":0.426800012588501},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.41179999709129333},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.40639999508857727},{"id":"https://openalex.org/C3018260909","wikidata":"https://www.wikidata.org/wiki/Q1322871","display_name":"Exploratory analysis","level":2,"score":0.38359999656677246},{"id":"https://openalex.org/C65835030","wikidata":"https://www.wikidata.org/wiki/Q1030681","display_name":"Brain size","level":3,"score":0.37439998984336853},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.3368000090122223},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.33410000801086426},{"id":"https://openalex.org/C77350462","wikidata":"https://www.wikidata.org/wiki/Q1125472","display_name":"Confounding","level":2,"score":0.33169999718666077},{"id":"https://openalex.org/C183905921","wikidata":"https://www.wikidata.org/wiki/Q1038757","display_name":"Multiple comparisons problem","level":2,"score":0.2784000039100647},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.2750000059604645},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.2741999924182892},{"id":"https://openalex.org/C20556612","wikidata":"https://www.wikidata.org/wiki/Q4469374","display_name":"Volume (thermodynamics)","level":2,"score":0.2651999890804291},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.26179999113082886},{"id":"https://openalex.org/C2780084366","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demographics","level":2,"score":0.2524999976158142},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.2515999972820282}],"mesh":[{"descriptor_ui":"D000096042","descriptor_name":"Symptom Burden","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004244","descriptor_name":"Dizziness","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D004244","descriptor_name":"Dizziness","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D004244","descriptor_name":"Dizziness","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007031","descriptor_name":"Hypothalamus","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D007031","descriptor_name":"Hypothalamus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008881","descriptor_name":"Migraine Disorders","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D008881","descriptor_name":"Migraine Disorders","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D008881","descriptor_name":"Migraine Disorders","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008881","descriptor_name":"Migraine Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D014717","descriptor_name":"Vertigo","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D014717","descriptor_name":"Vertigo","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D014717","descriptor_name":"Vertigo","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.3389/fneur.2026.1931533","doi":"https://doi.org/10.3389/fneur.2026.1931533","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fneur.2026.1931533","pdf_url":"https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2026.1931533/pdf","source":{"id":"https://openalex.org/S96975567","display_name":"Frontiers in Neurology","issn_l":"1664-2295","issn":["1664-2295"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neurology","raw_type":"journal-article"},{"id":"pmid:42834909","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42834909","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in neurology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13634837","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13634837/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Neurol","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:916a526cac884f2ba600607cfb73a277","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/916a526cac884f2ba600607cfb73a277","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Neurology, Vol 17 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fneur.2026.1931533","doi":"https://doi.org/10.3389/fneur.2026.1931533","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fneur.2026.1931533","pdf_url":"https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2026.1931533/pdf","source":{"id":"https://openalex.org/S96975567","display_name":"Frontiers in Neurology","issn_l":"1664-2295","issn":["1664-2295"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neurology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3889887555","display_name":null,"funder_award_id":"82202804","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7213880274.pdf","grobid_xml":"https://content.openalex.org/works/W7213880274.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W2029306017","https://openalex.org/W2046485521","https://openalex.org/W2059796825","https://openalex.org/W2074671051","https://openalex.org/W2128762423","https://openalex.org/W2343343747","https://openalex.org/W2410833637","https://openalex.org/W2512672638","https://openalex.org/W2801085490","https://openalex.org/W2968016611","https://openalex.org/W2970903952","https://openalex.org/W2986192478","https://openalex.org/W3002311230","https://openalex.org/W3080123676","https://openalex.org/W3200023722","https://openalex.org/W3207839467","https://openalex.org/W3210278014","https://openalex.org/W3216211358","https://openalex.org/W4200074088","https://openalex.org/W4307983934","https://openalex.org/W4384702015","https://openalex.org/W4390629588","https://openalex.org/W4390795451","https://openalex.org/W4399785218","https://openalex.org/W4408220067","https://openalex.org/W4410277990","https://openalex.org/W4415387372"],"related_works":["https://openalex.org/W7162288582","https://openalex.org/W7202161283","https://openalex.org/W7165562407","https://openalex.org/W4413027363","https://openalex.org/W2968016611","https://openalex.org/W7154193220","https://openalex.org/W7170075828","https://openalex.org/W4412932641","https://openalex.org/W7098623562","https://openalex.org/W2122554266"],"abstract_inverted_index":{"Background":[0],"Dizziness,":[1],"vertigo,":[2],"and":[3,47,60,76,85,95,234],"related":[4],"autonomic":[5],"symptoms":[6],"are":[7],"common":[8],"in":[9,192,217],"migraine,":[10],"but":[11,198],"whether":[12],"their":[13],"combined":[14],"symptom-frequency":[15],"burden":[16,209],"is":[17],"associated":[18,121,211],"with":[19,34,44,122,212,219,230],"hypothalamic":[20,49,118,215],"subregional":[21,225],"structure":[22],"remains":[23],"unclear.":[24],"Methods":[25],"This":[26,221],"exploratory":[27],"cross-sectional":[28],"secondary":[29],"analysis":[30],"included":[31],"39":[32],"women":[33,218],"ICHD-3-defined":[35],"migraine.":[36,220],"All":[37],"source":[38],"T1-weighted":[39],"images":[40],"were":[41,112],"processed":[42],"uniformly":[43],"FreeSurfer":[45],"7.4.1":[46],"automated":[48],"subunit":[50],"segmentation.":[51],"Blinded":[52],"quality":[53],"control":[54],"was":[55,68,103,120,210],"performed":[56],"without":[57],"clinical":[58],"data":[59],"independently":[61],"confirmed":[62],"by":[63],"a":[64,72,193,224],"neuroradiologist.":[65],"The":[66,149],"exposure":[67],"VSS-C":[69,123,170,206],"total":[70,92,124,207],"score,":[71],"composite":[73],"of":[74,183],"vertigo-balance":[75],"autonomic-anxiety":[77],"symptom":[78,208,232],"frequency.":[79],"Models":[80],"for":[81,89,227],"five":[82],"bilateral":[83],"subunits":[84],"whole-hypothalamus":[86],"volume":[87,119,216],"adjusted":[88],"age,":[90],"estimated":[91],"intracranial":[93],"volume,":[94],"baseline":[96],"monthly":[97],"migraine":[98],"days;":[99],"Benjamini-Hochberg":[100],"false-discovery-rate":[101],"correction":[102],"applied":[104],"across":[105],"the":[106,158,167,173,189],"six":[107,155],"outcomes.":[108],"Outcome-specific":[109],"quality-control":[110],"denominators":[111],"37":[113,160],"or":[114,181],"39.":[115],"Results":[116],"Anterior-superior":[117],"score":[125],"(n":[126],"=":[127,130,143,147,164],"39;":[128],"\u03b2":[129],"0.165":[131],"mm":[132,178],"3":[133,179],"per":[134],"point,":[135],"95%":[136],"confidence":[137],"interval":[138],"0.064":[139],"to":[140,157,176],"0.266,":[141],"p":[142,146,163],"0.0021;":[144],"BH-FDR-adjusted":[145],"0.0127).":[148],"association":[150],"remained":[151],"after":[152],"restricting":[153],"all":[154],"outcomes":[156],"same":[159,190],"participants":[161],"(BH-FDR-adjusted":[162],"0.0334).":[165],"Across":[166],"observed":[168],"20-point":[169],"interquartile":[171],"range,":[172],"coefficient":[174],"corresponded":[175],"3.31":[177],",":[180],"8.54%":[182],"mean":[184],"anterior-superior":[185,214],"volume.":[186],"DHI":[187],"identified":[188],"subregion":[191],"separately":[194],"corrected":[195],"supporting":[196],"analysis,":[197],"mutual":[199],"adjustment":[200],"attenuated":[201],"both":[202],"coefficients.":[203],"Conclusion":[204],"Higher":[205],"larger":[213],"result":[222],"identifies":[223],"target":[226],"prospective":[228],"replication":[229],"component-level":[231],"assessment":[233],"formal":[235],"vestibular":[236],"phenotyping.":[237]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2026-09-22T00:00:00"}