{"id":"https://openalex.org/W7213865796","doi":"https://doi.org/10.3390/healthcare14183077","title":"Evaluating Acupuncture for Chemotherapy-Induced Peripheral Neuropathic Pain: A Narrative Review of Clinical Evidence and Mechanistic Perspectives","display_name":"Evaluating Acupuncture for Chemotherapy-Induced Peripheral Neuropathic Pain: A Narrative Review of Clinical Evidence and Mechanistic Perspectives","publication_year":2026,"publication_date":"2026-09-18","ids":{"openalex":"https://openalex.org/W7213865796","doi":"https://doi.org/10.3390/healthcare14183077","pmid":"https://pubmed.ncbi.nlm.nih.gov/42793615","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13606048"},"language":"en","primary_location":{"id":"doi:10.3390/healthcare14183077","doi":"https://doi.org/10.3390/healthcare14183077","is_oa":true,"landing_page_url":"https://doi.org/10.3390/healthcare14183077","pdf_url":null,"source":{"id":"https://openalex.org/S4210214101","display_name":"Healthcare","issn_l":"2227-9032","issn":["2227-9032"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Healthcare","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/healthcare14183077","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5134856840","display_name":"Paula Sousa","orcid":"https://orcid.org/0000-0001-9082-8060","observed_orcids":["https://orcid.org/0000-0001-9082-8060"]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]},{"id":"https://openalex.org/I4405263123","display_name":"Instituto de Ci\u00eancias Biom\u00e9dicas Albel Salazar","ror":"https://ror.org/02trb6b02","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213","https://openalex.org/I4405263123"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Paula Sousa","raw_affiliation_strings":["CBSin, Centre of Biosciences in Integrative Health, 4250-105 Porto, Portugal","ICBAS, School of Medicine and Biomedical Sciences, University of Porto, 4050-313 Porto, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CBSin, Centre of Biosciences in Integrative Health, 4250-105 Porto, Portugal","institution_ids":["https://openalex.org/I182534213"]},{"raw_affiliation_string":"ICBAS, School of Medicine and Biomedical Sciences, University of Porto, 4050-313 Porto, Portugal","institution_ids":["https://openalex.org/I182534213","https://openalex.org/I4405263123"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092527137","display_name":"Madalena Deus","orcid":"https://orcid.org/0009-0002-8188-2289","observed_orcids":["https://orcid.org/0009-0002-8188-2289"]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Madalena Deus","raw_affiliation_strings":["CBSin, Centre of Biosciences in Integrative Health, 4250-105 Porto, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CBSin, Centre of Biosciences in Integrative Health, 4250-105 Porto, Portugal","institution_ids":["https://openalex.org/I182534213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102725236","display_name":"Mariana Pedrosa","orcid":"https://orcid.org/0009-0004-2789-6131","observed_orcids":["https://orcid.org/0009-0004-2789-6131"]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Mariana Pedrosa","raw_affiliation_strings":["CBSin, Centre of Biosciences in Integrative Health, 4250-105 Porto, Portugal"],"raw_orcid":"https://orcid.org/0009-0004-2789-6131","affiliations":[{"raw_affiliation_string":"CBSin, Centre of Biosciences in Integrative Health, 4250-105 Porto, Portugal","institution_ids":["https://openalex.org/I182534213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007364143","display_name":"Jorge Magalh\u00e3es Rodrigues","orcid":"https://orcid.org/0000-0001-5892-1855","observed_orcids":["https://orcid.org/0000-0001-5892-1855"]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]},{"id":"https://openalex.org/I4405263123","display_name":"Instituto de Ci\u00eancias Biom\u00e9dicas Albel Salazar","ror":"https://ror.org/02trb6b02","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213","https://openalex.org/I4405263123"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Jorge Magalh\u00e3es Rodrigues","raw_affiliation_strings":["CBSin, Centre of Biosciences in Integrative Health, 4250-105 Porto, Portugal","ICBAS, School of Medicine and Biomedical Sciences, University of Porto, 4050-313 Porto, Portugal"],"raw_orcid":"https://orcid.org/0000-0001-5892-1855","affiliations":[{"raw_affiliation_string":"CBSin, Centre of Biosciences in Integrative Health, 4250-105 Porto, Portugal","institution_ids":["https://openalex.org/I182534213"]},{"raw_affiliation_string":"ICBAS, School of Medicine and Biomedical Sciences, University of Porto, 4050-313 Porto, Portugal","institution_ids":["https://openalex.org/I182534213","https://openalex.org/I4405263123"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002234041","display_name":"Fabr\u00edcio Pereira","orcid":"https://orcid.org/0000-0003-3317-8756","observed_orcids":["https://orcid.org/0000-0003-3317-8756"]},"institutions":[{"id":"https://openalex.org/I66456633","display_name":"Universit\u00e9 de N\u00eemes","ror":"https://ror.org/044t4x544","country_code":"FR","type":"education","lineage":["https://openalex.org/I4405261603","https://openalex.org/I66456633"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Fabricio Pereira","raw_affiliation_strings":["MIPE, Universit\u00e9 de N\u00eemes, 30000 Nimes, France"],"raw_orcid":"https://orcid.org/0000-0003-3317-8756","affiliations":[{"raw_affiliation_string":"MIPE, Universit\u00e9 de N\u00eemes, 30000 Nimes, France","institution_ids":["https://openalex.org/I66456633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077696361","display_name":"Maria Bego\u00f1a Criado","orcid":"https://orcid.org/0000-0003-1750-5614","observed_orcids":["https://orcid.org/0000-0003-1750-5614"]},"institutions":[{"id":"https://openalex.org/I4210096930","display_name":"Cooperativa de Ensino Superior Polit\u00e9cnico e Universit\u00e1rio","ror":"https://ror.org/00w7bj245","country_code":"PT","type":"education","lineage":["https://openalex.org/I4210096930"]},{"id":"https://openalex.org/I4405253545","display_name":"Unidade de Investiga\u00e7\u00e3o em Toxicologia & Uma S\u00f3 Sa\u00fade","ror":"https://ror.org/00t11qq58","country_code":"PT","type":"education","lineage":["https://openalex.org/I4405253545"]}],"countries":["PT"],"is_corresponding":true,"raw_author_name":"Maria Bego\u00f1a Criado","raw_affiliation_strings":["Associate Laboratory i4HB\u2014Institute for Health and Bioeconomy, University Institute of Health Sciences, 4585-116 Gandra, Portugal","UCIBIO\u2014Applied Molecular Biosciences Unit, Toxicologic Pathology Research Laboratory, University Institute of Health Sciences (1H-TOXRUN, IUCS-CESPU), 4585-116 Gandra, Portugal"],"raw_orcid":"https://orcid.org/0000-0003-1750-5614","affiliations":[{"raw_affiliation_string":"Associate Laboratory i4HB\u2014Institute for Health and Bioeconomy, University Institute of Health Sciences, 4585-116 Gandra, Portugal","institution_ids":[]},{"raw_affiliation_string":"UCIBIO\u2014Applied Molecular Biosciences Unit, Toxicologic Pathology Research Laboratory, University Institute of Health Sciences (1H-TOXRUN, IUCS-CESPU), 4585-116 Gandra, Portugal","institution_ids":["https://openalex.org/I4210096930","https://openalex.org/I4405253545"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068123461","display_name":"Jorge Pereira Machado","orcid":"https://orcid.org/0000-0003-4570-5445","observed_orcids":["https://orcid.org/0000-0003-4570-5445"]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]},{"id":"https://openalex.org/I4405263123","display_name":"Instituto de Ci\u00eancias Biom\u00e9dicas Albel Salazar","ror":"https://ror.org/02trb6b02","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213","https://openalex.org/I4405263123"]}],"countries":["PT"],"is_corresponding":true,"raw_author_name":"Jorge Pereira Machado","raw_affiliation_strings":["CBSin, Centre of Biosciences in Integrative Health, 4250-105 Porto, Portugal","ICBAS, School of Medicine and Biomedical Sciences, University of Porto, 4050-313 Porto, Portugal"],"raw_orcid":"https://orcid.org/0000-0003-4570-5445","affiliations":[{"raw_affiliation_string":"CBSin, Centre of Biosciences in Integrative Health, 4250-105 Porto, Portugal","institution_ids":["https://openalex.org/I182534213"]},{"raw_affiliation_string":"ICBAS, School of Medicine and Biomedical Sciences, University of Porto, 4050-313 Porto, Portugal","institution_ids":["https://openalex.org/I182534213","https://openalex.org/I4405263123"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003220013","display_name":"Ant\u00f3nio Moreira","orcid":"https://orcid.org/0000-0001-9532-112X","observed_orcids":["https://orcid.org/0000-0001-9532-112X"]},"institutions":[{"id":"https://openalex.org/I4210114793","display_name":"Universidade Polit\u00e9cnica de Santar\u00e9m","ror":"https://ror.org/02bbx2g30","country_code":"PT","type":"education","lineage":["https://openalex.org/I4210114793"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Ant\u00f3nio Moreira","raw_affiliation_strings":["Research Center in Sports Sciences, Health Sciences and Human Development (CIDESD), Santar\u00e9m Polytechnic University, 2001-904 Santar\u00e9m, Portugal","Sport Sciences School of Rio Maior, Santar\u00e9m Polytechnic University, 2040-413 Rio Maior, Portugal"],"raw_orcid":"https://orcid.org/0000-0001-9532-112X","affiliations":[{"raw_affiliation_string":"Research Center in Sports Sciences, Health Sciences and Human Development (CIDESD), Santar\u00e9m Polytechnic University, 2001-904 Santar\u00e9m, Portugal","institution_ids":["https://openalex.org/I4210114793"]},{"raw_affiliation_string":"Sport Sciences School of Rio Maior, Santar\u00e9m Polytechnic University, 2040-413 Rio Maior, Portugal","institution_ids":["https://openalex.org/I4210114793"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5068123461","https://openalex.org/A5077696361"],"corresponding_institution_ids":["https://openalex.org/I182534213","https://openalex.org/I4210096930","https://openalex.org/I4405253545","https://openalex.org/I4405263123"],"apc_list":{"value":2700,"currency":"CHF","value_usd":3258},"apc_paid":{"value":2700,"currency":"CHF","value_usd":3258},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.56385405,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":"18","first_page":"3077","last_page":"3077"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11327","display_name":"Acupuncture Treatment Research Studies","score":0.8554999828338623,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11327","display_name":"Acupuncture Treatment Research Studies","score":0.8554999828338623,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11752","display_name":"Cancer Treatment and Pharmacology","score":0.13529999554157257,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11785","display_name":"Nausea and vomiting management","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acupuncture","display_name":"acupuncture","score":0.9990000128746033},{"id":"https://openalex.org/keywords/chemotherapy-induced-peripheral-neuropathy","display_name":"chemotherapy-induced peripheral neuropathy","score":0.8980000019073486},{"id":"https://openalex.org/keywords/neuropathic-pain","display_name":"neuropathic pain","score":0.9269999861717224},{"id":"https://openalex.org/keywords/non-pharmacological-pain-management","display_name":"non-pharmacological pain management","score":0.9160000085830688},{"id":"https://openalex.org/keywords/adjunctive-therapy","display_name":"adjunctive therapy","score":0.7519999742507935},{"id":"https://openalex.org/keywords/pain-prevention","display_name":"pain prevention","score":0.5370000004768372},{"id":"https://openalex.org/keywords/sensory-symptoms","display_name":"sensory symptoms","score":0.8019999861717224},{"id":"https://openalex.org/keywords/acupuncture-mechanism","display_name":"acupuncture mechanism","score":0.6340000033378601},{"id":"https://openalex.org/keywords/treatment-response-variability","display_name":"treatment response variability","score":0.39399999380111694}],"concepts":[{"id":"https://openalex.org/C56837625","wikidata":"https://www.wikidata.org/wiki/Q121713","display_name":"Acupuncture","level":3,"score":0.8693000078201294},{"id":"https://openalex.org/C3020000205","wikidata":"https://www.wikidata.org/wiki/Q2412849","display_name":"Narrative review","level":2,"score":0.8421000242233276},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7843999862670898},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.5582000017166138},{"id":"https://openalex.org/C189708586","wikidata":"https://www.wikidata.org/wiki/Q1504425","display_name":"Systematic review","level":3,"score":0.5102999806404114},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.4916999936103821},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.47440001368522644},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.4699999988079071},{"id":"https://openalex.org/C2777107010","wikidata":"https://www.wikidata.org/wiki/Q2798704","display_name":"Neuropathic pain","level":2,"score":0.4357999861240387},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.40790000557899475},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.3824999928474426},{"id":"https://openalex.org/C148482608","wikidata":"https://www.wikidata.org/wiki/Q17007018","display_name":"Clinical study design","level":3,"score":0.3758000135421753},{"id":"https://openalex.org/C19648533","wikidata":"https://www.wikidata.org/wiki/Q691640","display_name":"Evidence-based medicine","level":3,"score":0.3684000074863434},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.3668000102043152},{"id":"https://openalex.org/C2781118164","wikidata":"https://www.wikidata.org/wiki/Q1088113","display_name":"Chronic pain","level":2,"score":0.3416000008583069},{"id":"https://openalex.org/C199033989","wikidata":"https://www.wikidata.org/wiki/Q1318295","display_name":"Narrative","level":2,"score":0.3391000032424927},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.320499986410141},{"id":"https://openalex.org/C2909026353","wikidata":"https://www.wikidata.org/wiki/Q2712836","display_name":"Quantitative sensory testing","level":3,"score":0.3192000091075897},{"id":"https://openalex.org/C63363279","wikidata":"https://www.wikidata.org/wiki/Q5133848","display_name":"Clinical significance","level":2,"score":0.31369999051094055},{"id":"https://openalex.org/C2779318504","wikidata":"https://www.wikidata.org/wiki/Q1438035","display_name":"Research design","level":2,"score":0.30079999566078186},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.29010000824928284},{"id":"https://openalex.org/C3018162438","wikidata":"https://www.wikidata.org/wiki/Q1304270","display_name":"Adjunctive treatment","level":2,"score":0.28369998931884766},{"id":"https://openalex.org/C502991105","wikidata":"https://www.wikidata.org/wiki/Q5133849","display_name":"Clinical research","level":2,"score":0.2791999876499176},{"id":"https://openalex.org/C3018263421","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Human studies","level":2,"score":0.2572000026702881},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.2565000057220459},{"id":"https://openalex.org/C140608501","wikidata":"https://www.wikidata.org/wiki/Q7318358","display_name":"Review article","level":2,"score":0.2533000111579895}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/healthcare14183077","doi":"https://doi.org/10.3390/healthcare14183077","is_oa":true,"landing_page_url":"https://doi.org/10.3390/healthcare14183077","pdf_url":null,"source":{"id":"https://openalex.org/S4210214101","display_name":"Healthcare","issn_l":"2227-9032","issn":["2227-9032"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Healthcare","raw_type":"journal-article"},{"id":"pmid:42793615","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42793615","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Healthcare (Basel, Switzerland)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13606048","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13606048/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Healthcare (Basel)","raw_type":"Text"},{"id":"pmh:oai:HAL:hal-05848199v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-05848199","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Healthcare, 2026, 14 (18), pp.3077. ⟨10.3390/healthcare14183077⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.3390/healthcare14183077","doi":"https://doi.org/10.3390/healthcare14183077","is_oa":true,"landing_page_url":"https://doi.org/10.3390/healthcare14183077","pdf_url":null,"source":{"id":"https://openalex.org/S4210214101","display_name":"Healthcare","issn_l":"2227-9032","issn":["2227-9032"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Healthcare","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1997341496","https://openalex.org/W2014779151","https://openalex.org/W2071620144","https://openalex.org/W2114458368","https://openalex.org/W2310362320","https://openalex.org/W2541757731","https://openalex.org/W2581716246","https://openalex.org/W2767793280","https://openalex.org/W2803025801","https://openalex.org/W2897978942","https://openalex.org/W2942660786","https://openalex.org/W2979502932","https://openalex.org/W2989594970","https://openalex.org/W2995845719","https://openalex.org/W3011790834","https://openalex.org/W3043680095","https://openalex.org/W3110861798","https://openalex.org/W3135710054","https://openalex.org/W3207388101","https://openalex.org/W4206491089","https://openalex.org/W4295865713","https://openalex.org/W4311404286","https://openalex.org/W4318832908","https://openalex.org/W4386817599","https://openalex.org/W4407058947","https://openalex.org/W4407421638","https://openalex.org/W4409517499","https://openalex.org/W4413318000","https://openalex.org/W4413367161","https://openalex.org/W4414131012"],"related_works":["https://openalex.org/W2942660786","https://openalex.org/W1997341496","https://openalex.org/W3129108913","https://openalex.org/W7118021281","https://openalex.org/W2995845719","https://openalex.org/W7098636629","https://openalex.org/W7212121907","https://openalex.org/W2920981862","https://openalex.org/W2139176220","https://openalex.org/W3099652556"],"abstract_inverted_index":{"BACKGROUND/OBJECTIVES:":[0],"Despite":[1],"the":[2,55,61,71,116,197],"high":[3],"prevalence":[4],"of":[5,60,196,242],"chemotherapy-induced":[6],"peripheral":[7],"neuropathic":[8],"pain":[9,163,210],"(CIPNp),":[10],"its":[11],"management":[12],"remains":[13],"challenging,":[14],"and":[15,27,40,57,76,110,128,151,164,188,191,229,244],"reliable":[16],"preventive":[17],"strategies":[18],"are":[19,233],"still":[20],"lacking.":[21],"Current":[22],"treatment":[23,239],"is":[24,177],"largely":[25],"symptomatic":[26],"often":[28],"provides":[29],"only":[30],"modest":[31],"benefits,":[32],"as":[33,50],"available":[34,62],"pharmacological":[35],"therapies":[36],"have":[37],"shown":[38],"limited":[39,178,192],"inconsistent":[41],"efficacy.":[42],"In":[43],"this":[44],"context,":[45],"acupuncture":[46,81,156,184],"has":[47],"been":[48],"investigated":[49],"a":[51,124,217],"non-pharmacological":[52],"intervention,":[53],"but":[54],"certainty":[56],"clinical":[58,72,101,106],"applicability":[59],"evidence":[63,152],"remain":[64],"unclear.":[65],"This":[66],"critical":[67],"narrative":[68,87,111],"review":[69,88],"examines":[70],"evidence,":[73],"mechanistic":[74,108,199],"plausibility,":[75],"current":[77],"research":[78],"gaps":[79],"concerning":[80],"for":[82,221],"CIPNp.":[83,226],"METHODS:":[84],"A":[85],"non-systematic":[86],"was":[89,137,142],"conducted":[90],"with":[91,160,170,224],"preference":[92],"given":[93],"to":[94,115,123,235],"peer-reviewed":[95],"articles":[96],"published":[97],"in":[98,162,167,174,208],"English,":[99],"including":[100],"trials,":[102],"systematic":[103,126],"reviews,":[104],"meta-analyses,":[105],"guidelines,":[107],"studies,":[109],"reviews":[112],"considered":[113,216],"relevant":[114],"objectives.":[117],"Publications":[118],"were":[119],"not":[120],"selected":[121,222],"according":[122],"predefined":[125],"protocol,":[127],"no":[129],"formal":[130],"quality":[131],"assessment,":[132],"risk-of-bias":[133],"analysis,":[134],"or":[135,205],"meta-analysis":[136],"performed.":[138],"The":[139],"extracted":[140],"information":[141],"organized":[143],"thematically":[144],"rather":[145],"than":[146],"quantitatively.":[147],"RESULTS:":[148],"Clinical":[149],"trials":[150,232],"syntheses":[153],"suggest":[154],"that":[155],"may":[157,214],"be":[158,215],"associated":[159],"reductions":[161],"sensory":[165],"symptoms":[166],"some":[168],"patients":[169,223],"CIPN.":[171],"However,":[172],"confidence":[173],"these":[175],"findings":[176],"by":[179],"small":[180],"samples":[181],"sizes,":[182],"heterogeneous":[183],"protocols,":[185,240],"variable":[186],"comparators":[187],"outcome":[189],"measures,":[190],"long-term":[193],"follow-up.":[194],"Much":[195],"proposed":[198],"rationale":[200],"derives":[201],"from":[202],"animal":[203],"models":[204],"human":[206],"studies":[207],"non-CIPN":[209],"conditions.":[211],"CONCLUSIONS:":[212],"Acupuncture":[213],"monitored":[218],"adjunctive":[219],"option":[220],"persistent":[225],"More":[227],"rigorous":[228],"adequately":[230],"powered":[231],"required":[234],"determine":[236],"efficacy,":[237],"optimal":[238],"durability":[241],"benefit,":[243],"potential":[245],"treatment-response":[246],"modifiers.":[247]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2026-09-22T00:00:00"}