{"id":"https://openalex.org/W7213787193","doi":"https://doi.org/10.64898/2026.09.17.26363351","title":"A longitudinal study of age-related traits and cognitive function: The Collaborative Amish Aging and Memory Project (CAAMP)","display_name":"A longitudinal study of age-related traits and cognitive function: The Collaborative Amish Aging and Memory Project (CAAMP)","publication_year":2026,"publication_date":"2026-09-20","ids":{"openalex":"https://openalex.org/W7213787193","doi":"https://doi.org/10.64898/2026.09.17.26363351","pmid":"https://pubmed.ncbi.nlm.nih.gov/42779909","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13596672"},"language":"en","primary_location":{"id":"doi:10.64898/2026.09.17.26363351","doi":"https://doi.org/10.64898/2026.09.17.26363351","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.17.26363351","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/20/2026.09.17.26363351.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/20/2026.09.17.26363351.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5152283750","display_name":"Dana Z. Jian","orcid":"https://orcid.org/0009-0006-8002-162X","observed_orcids":["https://orcid.org/0009-0006-8002-162X"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Dana Z. Jian","raw_affiliation_strings":["Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA"],"raw_orcid":"https://orcid.org/0009-0006-8002-162X","affiliations":[{"raw_affiliation_string":"Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066783581","display_name":"Rene\u00e9 A. Laux","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Renee A. Laux","raw_affiliation_strings":["Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071977840","display_name":"Yeunjoo E. Song","orcid":"https://orcid.org/0000-0002-7452-3731","observed_orcids":["https://orcid.org/0000-0002-7452-3731"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yeunjoo E. Song","raw_affiliation_strings":["Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111846941","display_name":"Audrey Lynn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Audrey Lynn","raw_affiliation_strings":["Cleveland Institute for Computational Biology, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA","Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cleveland Institute for Computational Biology, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]},{"raw_affiliation_string":"Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007357271","display_name":"Kristy L. S. Miskimen","orcid":"https://orcid.org/0000-0003-0376-9053","observed_orcids":["https://orcid.org/0000-0003-0376-9053"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kristy Miskimen","raw_affiliation_strings":["Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115699400","display_name":"Alex V. Gulyayev","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alex Gulyayev","raw_affiliation_strings":["John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089289757","display_name":"Sarada L. Fuzzell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarada L. Fuzzell","raw_affiliation_strings":["Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047337415","display_name":"Sherri D. Hochstetler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sherri D. Hochstetler","raw_affiliation_strings":["Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5145687980","display_name":"Dawn Miller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dawn Miller","raw_affiliation_strings":["Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063277498","display_name":"Penelope L. Miron","orcid":"https://orcid.org/0009-0003-2631-5182","observed_orcids":["https://orcid.org/0009-0003-2631-5182"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Penelope Miron","raw_affiliation_strings":["Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071820702","display_name":"Laura J. Caywood","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laura J. Caywood","raw_affiliation_strings":["John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034664934","display_name":"Jason E. Clouse","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jason E. Clouse","raw_affiliation_strings":["John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038676225","display_name":"Sharlene D. Herington","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sharlene D. Herington","raw_affiliation_strings":["John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062996292","display_name":"Michael B. Prough","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael B. Prough","raw_affiliation_strings":["John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109439277","display_name":"Larry Deon Adams","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Larry D. Adams","raw_affiliation_strings":["John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040839835","display_name":"Yining Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yining Liu","raw_affiliation_strings":["Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121161851","display_name":"Noel C. Moore","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Noel C. Moore","raw_affiliation_strings":["Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001834580","display_name":"Daniel A. Dorfsman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]},{"id":"https://openalex.org/I4210131692","display_name":"Dr. John T. Macdonald Foundation","ror":"https://ror.org/02vawgn43","country_code":"US","type":"other","lineage":["https://openalex.org/I4210131692"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel A. Dorfsman","raw_affiliation_strings":["Dr. John T. Macdonald Foundation of Human Genetics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dr. John T. Macdonald Foundation of Human Genetics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","institution_ids":["https://openalex.org/I145608581","https://openalex.org/I4210131692"]},{"raw_affiliation_string":"John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138972547","display_name":"Paula Ogrocki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108791","display_name":"University Hospitals Cleveland Medical Center","ror":"https://ror.org/01gc0wp38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210108791"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paula Ogrocki","raw_affiliation_strings":["Department of Neurology, Case Western Reserve University School of Medicine, 10900 Euclid Ave, Cleveland, OH 44106, USA","University Hospitals Cleveland Medical Center, 11100 Euclid Ave, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Case Western Reserve University School of Medicine, 10900 Euclid Ave, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]},{"raw_affiliation_string":"University Hospitals Cleveland Medical Center, 11100 Euclid Ave, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I4210108791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062686238","display_name":"Alan Jay Lerner","orcid":"https://orcid.org/0000-0001-9447-6154","observed_orcids":["https://orcid.org/0000-0001-9447-6154"]},"institutions":[{"id":"https://openalex.org/I4210108791","display_name":"University Hospitals Cleveland Medical Center","ror":"https://ror.org/01gc0wp38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210108791"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alan J. Lerner","raw_affiliation_strings":["Department of Neurology, Case Western Reserve University School of Medicine, 10900 Euclid Ave, Cleveland, OH 44106, USA","University Hospitals Cleveland Medical Center, 11100 Euclid Ave, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Case Western Reserve University School of Medicine, 10900 Euclid Ave, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]},{"raw_affiliation_string":"University Hospitals Cleveland Medical Center, 11100 Euclid Ave, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I4210108791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039717261","display_name":"Jeffery M. Vance","orcid":"https://orcid.org/0000-0003-3815-8199","observed_orcids":["https://orcid.org/0000-0003-3815-8199"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]},{"id":"https://openalex.org/I4210131692","display_name":"Dr. John T. Macdonald Foundation","ror":"https://ror.org/02vawgn43","country_code":"US","type":"other","lineage":["https://openalex.org/I4210131692"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffery M. Vance","raw_affiliation_strings":["Dr. John T. Macdonald Foundation of Human Genetics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dr. John T. Macdonald Foundation of Human Genetics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","institution_ids":["https://openalex.org/I145608581","https://openalex.org/I4210131692"]},{"raw_affiliation_string":"John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039221620","display_name":"Michael L. Cuccaro","orcid":"https://orcid.org/0000-0003-4769-0785","observed_orcids":["https://orcid.org/0000-0003-4769-0785"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]},{"id":"https://openalex.org/I4210131692","display_name":"Dr. John T. Macdonald Foundation","ror":"https://ror.org/02vawgn43","country_code":"US","type":"other","lineage":["https://openalex.org/I4210131692"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael L. Cuccaro","raw_affiliation_strings":["Dr. John T. Macdonald Foundation of Human Genetics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dr. John T. Macdonald Foundation of Human Genetics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","institution_ids":["https://openalex.org/I145608581","https://openalex.org/I4210131692"]},{"raw_affiliation_string":"John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069324665","display_name":"Margaret Ann Pericak\u2010Vance","orcid":"https://orcid.org/0000-0001-7283-8804","observed_orcids":["https://orcid.org/0000-0001-7283-8804","https://orcid.org/0000-0002-3309-1303"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]},{"id":"https://openalex.org/I4210131692","display_name":"Dr. John T. Macdonald Foundation","ror":"https://ror.org/02vawgn43","country_code":"US","type":"other","lineage":["https://openalex.org/I4210131692"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Margaret A. Pericak-Vance","raw_affiliation_strings":["Dr. John T. Macdonald Foundation of Human Genetics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dr. John T. Macdonald Foundation of Human Genetics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","institution_ids":["https://openalex.org/I145608581","https://openalex.org/I4210131692"]},{"raw_affiliation_string":"John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088628502","display_name":"William K. Scott","orcid":"https://orcid.org/0000-0001-9336-6404","observed_orcids":["https://orcid.org/0000-0001-9336-6404"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]},{"id":"https://openalex.org/I4210131692","display_name":"Dr. John T. Macdonald Foundation","ror":"https://ror.org/02vawgn43","country_code":"US","type":"other","lineage":["https://openalex.org/I4210131692"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William K. Scott","raw_affiliation_strings":["Dr. John T. Macdonald Foundation of Human Genetics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA"],"raw_orcid":"https://orcid.org/0000-0001-9336-6404","affiliations":[{"raw_affiliation_string":"Dr. John T. Macdonald Foundation of Human Genetics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","institution_ids":["https://openalex.org/I145608581","https://openalex.org/I4210131692"]},{"raw_affiliation_string":"John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL 33136, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020266650","display_name":"Jonathan L. Haines","orcid":"https://orcid.org/0000-0002-4351-4728","observed_orcids":["https://orcid.org/0000-0002-4351-4728"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan L. Haines","raw_affiliation_strings":["Cleveland Institute for Computational Biology, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA","Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cleveland Institute for Computational Biology, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]},{"raw_affiliation_string":"Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, 2013 Cornell Road, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5152283750"],"corresponding_institution_ids":["https://openalex.org/I58956616"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11265","display_name":"Aging and Gerontology Research","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/3204","display_name":"Developmental and Educational Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amish","display_name":"Amish","score":0.6549999713897705},{"id":"https://openalex.org/keywords/cognitive-function","display_name":"cognitive function","score":0.5910000205039978},{"id":"https://openalex.org/keywords/alzheimer-s-disease-and-related-dementias","display_name":"Alzheimer's disease and related dementias","score":0.8450000286102295},{"id":"https://openalex.org/keywords/successful-aging","display_name":"successful aging","score":0.9620000123977661},{"id":"https://openalex.org/keywords/mild-cognitive-impairment","display_name":"mild cognitive impairment","score":0.871999979019165},{"id":"https://openalex.org/keywords/longitudinal-cohort","display_name":"longitudinal cohort","score":0.656000018119812},{"id":"https://openalex.org/keywords/founder-populations","display_name":"founder populations","score":0.7590000033378601},{"id":"https://openalex.org/keywords/plasma-biomarkers","display_name":"plasma biomarkers","score":0.8510000109672546},{"id":"https://openalex.org/keywords/multigenerational-pedigree","display_name":"multigenerational pedigree","score":0.8529999852180481}],"concepts":[{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.7401000261306763},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5813999772071838},{"id":"https://openalex.org/C2777895361","wikidata":"https://www.wikidata.org/wiki/Q1758614","display_name":"Longitudinal study","level":2,"score":0.5684999823570251},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.5629000067710876},{"id":"https://openalex.org/C2986811735","wikidata":"https://www.wikidata.org/wiki/Q4692577","display_name":"Cognitive aging","level":3,"score":0.5253000259399414},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.5156999826431274},{"id":"https://openalex.org/C2984863031","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Cognitive decline","level":4,"score":0.4966000020503998},{"id":"https://openalex.org/C88576662","wikidata":"https://www.wikidata.org/wiki/Q18646","display_name":"Episodic memory","level":3,"score":0.4878999888896942},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.43529999256134033},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.43389999866485596},{"id":"https://openalex.org/C134290984","wikidata":"https://www.wikidata.org/wiki/Q5141241","display_name":"Cognitive skill","level":3,"score":0.43209999799728394},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.4253000020980835},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.4242999851703644},{"id":"https://openalex.org/C185711340","wikidata":"https://www.wikidata.org/wiki/Q5347381","display_name":"Effects of sleep deprivation on cognitive performance","level":3,"score":0.42260000109672546},{"id":"https://openalex.org/C6057870","wikidata":"https://www.wikidata.org/wiki/Q5141248","display_name":"Cognitive test","level":3,"score":0.4059000015258789},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.33880001306533813},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.32899999618530273},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.3215999901294708},{"id":"https://openalex.org/C79544238","wikidata":"https://www.wikidata.org/wiki/Q423243","display_name":"Activities of daily living","level":2,"score":0.2985000014305115},{"id":"https://openalex.org/C67739388","wikidata":"https://www.wikidata.org/wiki/Q579471","display_name":"Cognitive reserve","level":4,"score":0.2924000024795532},{"id":"https://openalex.org/C142853389","wikidata":"https://www.wikidata.org/wiki/Q744778","display_name":"Association (psychology)","level":2,"score":0.28200000524520874},{"id":"https://openalex.org/C2776035688","wikidata":"https://www.wikidata.org/wiki/Q1606558","display_name":"Affect (linguistics)","level":2,"score":0.26759999990463257},{"id":"https://openalex.org/C2776656118","wikidata":"https://www.wikidata.org/wiki/Q6815713","display_name":"Memory clinic","level":4,"score":0.26249998807907104},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2572999894618988},{"id":"https://openalex.org/C1691868","wikidata":"https://www.wikidata.org/wiki/Q1811049","display_name":"Life course approach","level":2,"score":0.25699999928474426},{"id":"https://openalex.org/C2780673598","wikidata":"https://www.wikidata.org/wiki/Q285223","display_name":"Genetic testing","level":2,"score":0.25200000405311584}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.64898/2026.09.17.26363351","doi":"https://doi.org/10.64898/2026.09.17.26363351","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.17.26363351","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/20/2026.09.17.26363351.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},{"id":"pmid:42779909","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42779909","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"medRxiv : the preprint server for health sciences","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13596672","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13596672/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"medRxiv","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.64898/2026.09.17.26363351","doi":"https://doi.org/10.64898/2026.09.17.26363351","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.17.26363351","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/20/2026.09.17.26363351.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9476000070571899}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G9000860728","display_name":"Protective Genetic Variants for Alzheimer Disease in the Amish - RENEWAL","funder_award_id":"R01AG058066","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G9000916609","display_name":"PIGE: The Program Integrating Genomics and the Environment","funder_award_id":"T32ES036169","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"}],"funders":[{"id":"https://openalex.org/F4320309249","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92"},{"id":"https://openalex.org/F4320310281","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666"},{"id":"https://openalex.org/F4320310622","display_name":"School of Medicine, Case Western Reserve University","ror":"https://ror.org/051fd9666"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332699","display_name":"Leonard M. Miller School of Medicine","ror":"https://ror.org/02dgjyy92"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337361","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7213787193.pdf","grobid_xml":"https://content.openalex.org/works/W7213787193.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W82159019","https://openalex.org/W1488336305","https://openalex.org/W1767653793","https://openalex.org/W1974157095","https://openalex.org/W1978695715","https://openalex.org/W1980316292","https://openalex.org/W1982519218","https://openalex.org/W2000404120","https://openalex.org/W2008825052","https://openalex.org/W2027875873","https://openalex.org/W2036362108","https://openalex.org/W2039480559","https://openalex.org/W2042807408","https://openalex.org/W2045528165","https://openalex.org/W2051467750","https://openalex.org/W2090271811","https://openalex.org/W2112519660","https://openalex.org/W2115017507","https://openalex.org/W2122162933","https://openalex.org/W2132831532","https://openalex.org/W2137182575","https://openalex.org/W2153564718","https://openalex.org/W2156220037","https://openalex.org/W2158766477","https://openalex.org/W2168914476","https://openalex.org/W2582524520","https://openalex.org/W2739642009","https://openalex.org/W2801087040","https://openalex.org/W2979383104","https://openalex.org/W3094323304","https://openalex.org/W3102449044","https://openalex.org/W3106890522","https://openalex.org/W3126160703","https://openalex.org/W3181504473","https://openalex.org/W4225246326","https://openalex.org/W4226319029","https://openalex.org/W4249279487","https://openalex.org/W4286005696","https://openalex.org/W4289932812","https://openalex.org/W4319590785","https://openalex.org/W4327681326","https://openalex.org/W4385725226","https://openalex.org/W4405699222","https://openalex.org/W4411078080","https://openalex.org/W4413650714","https://openalex.org/W4415257705","https://openalex.org/W4416052538","https://openalex.org/W7141592407"],"related_works":["https://openalex.org/W4225246326","https://openalex.org/W4210806856","https://openalex.org/W3112424578","https://openalex.org/W2981016459","https://openalex.org/W2016745788","https://openalex.org/W3112018008","https://openalex.org/W3111465702","https://openalex.org/W4210588525","https://openalex.org/W2465902564","https://openalex.org/W2144605224"],"abstract_inverted_index":{"INTRODUCTION:":[0],"The":[1,31,148],"Collaborative":[2],"Amish":[3,26,68],"Aging":[4],"and":[5,21,28,39,46,54,63,72,85,104,139,163,183,187,199,227,244],"Memory":[6],"Project":[7],"(CAAMP)":[8],"is":[9],"an":[10,107],"ongoing":[11],"longitudinal":[12],"study":[13,216],"spanning":[14],"multiple":[15,164],"sites,":[16],"focused":[17],"on":[18],"cognitive":[19,55,119,133,142,155,161,231],"function":[20],"age-related":[22,48,235],"traits":[23,33],"in":[24,70],"Midwestern":[25],"(Ohio":[27],"Indiana)":[29],"communities.":[30],"primary":[32],"of":[34,114,172,197,211,217,240],"interest":[35],"include":[36],"Alzheimer":[37,137,146,204],"Disease":[38],"related":[40],"dementias":[41],"(ADRD),":[42],"successful":[43],"aging":[44],"(SA),":[45],"other":[47,234],"conditions.":[49],"METHODS:":[50],"CAAMP":[51,91,174,192],"integrates":[52],"clinical":[53],"assessments":[56,162],"with":[57,106],"family":[58],"history,":[59],"genealogical,":[60],"genomic,":[61],"biospecimen,":[62],"biomarker":[64,189],"data":[65],"collected":[66],"across":[67],"communities":[69],"Ohio":[71],"Indiana.":[73],"Cognitive":[74],"diagnoses":[75],"are":[76,168],"assigned":[77],"through":[78],"consensus":[79],"adjudication":[80],"using":[81],"clinical,":[82],"cognitive,":[83],"functional,":[84],"informant":[86],"data.":[87],"RESULTS:":[88],"To":[89],"date,":[90],"has":[92],"enrolled":[93],"3,978":[94],"participants":[95],"(mean":[96],"age":[97],"78.6":[98],"(SD":[99],"=":[100],"7.9),":[101],"59.1%":[102],"female,":[103],"83%":[105],"education":[108],"level":[109],"at":[110,157],"the":[111,122,194,208,225],"eighth":[112],"grade),":[113],"whom":[115],"2,928":[116],"have":[117,153],"consensus-adjudicated":[118],"status.":[120],"At":[121],"most":[123],"recent":[124],"assessment,":[125],"66.6%":[126],"were":[127],"cognitively":[128],"unimpaired,":[129],"9.9%":[130],"had":[131,136,141],"mild":[132],"impairment,":[134,143],"8.9%":[135],"disease,":[138],"4.5%":[140],"but":[144],"not":[145,152],"disease.":[147],"remaining":[149],"1,050":[150],"did":[151],"detailed":[154],"evaluations":[156],"their":[158],"enrollment.":[159],"Longitudinal":[160],"biospecimen":[165],"sample":[166],"types":[167],"available":[169],"for":[170],"subsets":[171],"participants.":[173],"further":[175],"includes":[176],"extensive":[177],"multigenerational":[178],"pedigree":[179],"information,":[180],"genome-wide":[181],"genotype":[182],"whole-genome":[184],"sequencing":[185],"data,":[186],"plasma":[188],"measurements.":[190],"DISCUSSION:":[191],"illuminates":[193],"genetic":[195,226],"underpinnings":[196],"cognition":[198],"late":[200],"life":[201],"diseases,":[202],"particularly":[203],"Disease,":[205],"by":[206],"leveraging":[207],"special":[209],"characteristics":[210],"a":[212],"founder":[213],"population.":[214],"Continued":[215],"this":[218],"prospective":[219],"cohort":[220],"provides":[221],"opportunities":[222],"to":[223],"identify":[224],"biological":[228],"factors":[229],"driving":[230],"outcomes":[232],"alongside":[233],"conditions,":[236],"advancing":[237],"our":[238],"understanding":[239],"both":[241],"disease":[242],"risk":[243],"protection.":[245]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-09-21T00:00:00"}