{"id":"https://openalex.org/W7213626724","doi":"https://doi.org/10.63946/onmt/19288","title":"Molecularly Imprinted Polymer Biofunctionalized Optical Fiber-Tip Quasi-Random Extrinsic Interferometer for Selective Triple-Negative Breast Cancer Cells Detection","display_name":"Molecularly Imprinted Polymer Biofunctionalized Optical Fiber-Tip Quasi-Random Extrinsic Interferometer for Selective Triple-Negative Breast Cancer Cells Detection","publication_year":2026,"publication_date":"2026-09-19","ids":{"openalex":"https://openalex.org/W7213626724","doi":"https://doi.org/10.63946/onmt/19288"},"language":"en","primary_location":{"id":"doi:10.63946/onmt/19288","doi":"https://doi.org/10.63946/onmt/19288","is_oa":false,"landing_page_url":"https://doi.org/10.63946/onmt/19288","pdf_url":null,"source":{"id":"https://openalex.org/S5407052920","display_name":"Oncology Nuclear Medicine and Transplantology","issn_l":"3105-8760","issn":["3105-8760"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncology, Nuclear Medicine and Transplantology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5145759463","display_name":"Bakdaulet Yendibay","orcid":"https://orcid.org/0009-0005-7894-951X","observed_orcids":["https://orcid.org/0009-0005-7894-951X"]},"institutions":[{"id":"https://openalex.org/I60559429","display_name":"Nazarbayev University","ror":"https://ror.org/052bx8q98","country_code":"KZ","type":"education","lineage":["https://openalex.org/I60559429"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"Bakdaulet Yendibay","raw_affiliation_strings":["Department of Chemical and Materials Engineering, School of Engineering, Nazarbayev University, Astana, Kazakhstan","Laboratory of Biosensors and Bioinstruments, Center for Life Sciences, National Laboratory Astana, Astana, Kazakhstan"],"raw_orcid":"https://orcid.org/0009-0005-7894-951X","affiliations":[{"raw_affiliation_string":"Department of Chemical and Materials Engineering, School of Engineering, Nazarbayev University, Astana, Kazakhstan","institution_ids":["https://openalex.org/I60559429"]},{"raw_affiliation_string":"Laboratory of Biosensors and Bioinstruments, Center for Life Sciences, National Laboratory Astana, Astana, Kazakhstan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020345249","display_name":"Akmaral Suleimenova","orcid":"https://orcid.org/0000-0003-2102-4426","observed_orcids":["https://orcid.org/0000-0003-2102-4426","https://orcid.org/0009-0006-2130-7572"]},"institutions":[{"id":"https://openalex.org/I60559429","display_name":"Nazarbayev University","ror":"https://ror.org/052bx8q98","country_code":"KZ","type":"education","lineage":["https://openalex.org/I60559429"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"Akmaral Suleimenova","raw_affiliation_strings":["Department of Chemistry, School of Sciences and Humanities, Nazarbayev University, Astana, Kazakhstan","Nazarbayev University Research Administration, Astana, Kazakhstan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, School of Sciences and Humanities, Nazarbayev University, Astana, Kazakhstan","institution_ids":["https://openalex.org/I60559429"]},{"raw_affiliation_string":"Nazarbayev University Research Administration, Astana, Kazakhstan","institution_ids":["https://openalex.org/I60559429"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121644579","display_name":"Aigerim Omirzakova","orcid":"https://orcid.org/0009-0009-0141-3660","observed_orcids":["https://orcid.org/0009-0009-0141-3660"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aigerim Omirzakova","raw_affiliation_strings":["Laboratory of Biosensors and Bioinstruments, Center for Life Sciences, National Laboratory Astana, Astana, Kazakhstan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biosensors and Bioinstruments, Center for Life Sciences, National Laboratory Astana, Astana, Kazakhstan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026650709","display_name":"Lyazzat Mukhangaliyeva","orcid":"https://orcid.org/0000-0001-6508-1671","observed_orcids":["https://orcid.org/0000-0001-6508-1671"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lyazzat Mukhangaliyeva","raw_affiliation_strings":["Laboratory of Biosensors and Bioinstruments, Center for Life Sciences, National Laboratory Astana, Astana, Kazakhstan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biosensors and Bioinstruments, Center for Life Sciences, National Laboratory Astana, Astana, Kazakhstan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030942263","display_name":"Marzhan Nurlankyzy","orcid":"https://orcid.org/0000-0002-1551-9599","observed_orcids":["https://orcid.org/0000-0002-1551-9599"]},"institutions":[{"id":"https://openalex.org/I60559429","display_name":"Nazarbayev University","ror":"https://ror.org/052bx8q98","country_code":"KZ","type":"education","lineage":["https://openalex.org/I60559429"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"Marzhan Nurlankyzy","raw_affiliation_strings":["Laboratory of Biosensors and Bioinstruments, Center for Life Sciences, National Laboratory Astana, Astana, Kazakhstan","Nazarbayev University Research Administration, Astana, Kazakhstan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biosensors and Bioinstruments, Center for Life Sciences, National Laboratory Astana, Astana, Kazakhstan","institution_ids":[]},{"raw_affiliation_string":"Nazarbayev University Research Administration, Astana, Kazakhstan","institution_ids":["https://openalex.org/I60559429"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5151864560","display_name":"Ramazan Ashirkhan","orcid":"https://orcid.org/0009-0005-1121-0454","observed_orcids":["https://orcid.org/0009-0005-1121-0454"]},"institutions":[{"id":"https://openalex.org/I60559429","display_name":"Nazarbayev University","ror":"https://ror.org/052bx8q98","country_code":"KZ","type":"education","lineage":["https://openalex.org/I60559429"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"Ramazan Ashirkhan","raw_affiliation_strings":["Department of Electrical and Computer Engineering, School of Engineering and Digital Sciences, Nazarbayev University, Astana, Kazakhstan","Laboratory of Biosensors and Bioinstruments, Center for Life Sciences, National Laboratory Astana, Astana, Kazakhstan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, School of Engineering and Digital Sciences, Nazarbayev University, Astana, Kazakhstan","institution_ids":["https://openalex.org/I60559429"]},{"raw_affiliation_string":"Laboratory of Biosensors and Bioinstruments, Center for Life Sciences, National Laboratory Astana, Astana, Kazakhstan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114375572","display_name":"Wilfried Blanc","orcid":"https://orcid.org/0000-0002-7512-3916","observed_orcids":["https://orcid.org/0000-0002-7512-3916"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I201841394","display_name":"Universit\u00e9 C\u00f4te d'Azur","ror":"https://ror.org/019tgvf94","country_code":"FR","type":"education","lineage":["https://openalex.org/I201841394"]},{"id":"https://openalex.org/I4210149294","display_name":"Institut de Physique de Nice","ror":"https://ror.org/042cesy50","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I201841394","https://openalex.org/I4210149294"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Wilfried Blanc","raw_affiliation_strings":["INPHYNI, CNRS, Universit\u00e9 C\u00f4te d\u2019Azur, Nice, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INPHYNI, CNRS, Universit\u00e9 C\u00f4te d\u2019Azur, Nice, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I201841394","https://openalex.org/I4210149294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032369315","display_name":"Daniele Tosi","orcid":"https://orcid.org/0000-0002-6500-4964","observed_orcids":["https://orcid.org/0000-0002-6500-4964"]},"institutions":[{"id":"https://openalex.org/I60559429","display_name":"Nazarbayev University","ror":"https://ror.org/052bx8q98","country_code":"KZ","type":"education","lineage":["https://openalex.org/I60559429"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"Daniele Tosi","raw_affiliation_strings":["Department of Electrical and Computer Engineering, School of Engineering and Digital Sciences, Nazarbayev University, Astana, Kazakhstan","Laboratory of Biosensors and Bioinstruments, Center for Life Sciences, National Laboratory Astana, Astana, Kazakhstan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, School of Engineering and Digital Sciences, Nazarbayev University, Astana, Kazakhstan","institution_ids":["https://openalex.org/I60559429"]},{"raw_affiliation_string":"Laboratory of Biosensors and Bioinstruments, Center for Life Sciences, National Laboratory Astana, Astana, Kazakhstan","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025666277","display_name":"Zhannat Ashikbayeva","orcid":"https://orcid.org/0000-0001-9057-5876","observed_orcids":["https://orcid.org/0000-0001-9057-5876"]},"institutions":[{"id":"https://openalex.org/I60559429","display_name":"Nazarbayev University","ror":"https://ror.org/052bx8q98","country_code":"KZ","type":"education","lineage":["https://openalex.org/I60559429"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"Zhannat Ashikbayeva","raw_affiliation_strings":["Department of Chemistry, School of Sciences and Humanities, Nazarbayev University, Astana, Kazakhstan","Laboratory of Biosensors and Bioinstruments, Center for Life Sciences, National Laboratory Astana, Astana, Kazakhstan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, School of Sciences and Humanities, Nazarbayev University, Astana, Kazakhstan","institution_ids":["https://openalex.org/I60559429"]},{"raw_affiliation_string":"Laboratory of Biosensors and Bioinstruments, Center for Life Sciences, National Laboratory Astana, Astana, Kazakhstan","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"2","issue":"3, Suppl. 1","first_page":"onmt_A6","last_page":"onmt_A6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10180","display_name":"Analytical chemistry methods development","score":0.8389000296592712,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10180","display_name":"Analytical chemistry methods development","score":0.8389000296592712,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10205","display_name":"Advanced Fiber Optic Sensors","score":0.066600002348423,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.01759999990463257,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/molecularly-imprinted-polymers","display_name":"molecularly imprinted polymers","score":0.9409999847412109},{"id":"https://openalex.org/keywords/polydopamine","display_name":"polydopamine","score":0.9539999961853027},{"id":"https://openalex.org/keywords/triple-negative-breast-cancer","display_name":"triple-negative breast cancer","score":0.8949999809265137},{"id":"https://openalex.org/keywords/tumor-cell-detection","display_name":"cancer cell detection","score":0.890999972820282},{"id":"https://openalex.org/keywords/optical-fiber-tip","display_name":"optical fiber tip","score":0.4909999966621399},{"id":"https://openalex.org/keywords/fiber-optic-biosensor","display_name":"optical fiber biosensor","score":0.7390000224113464},{"id":"https://openalex.org/keywords/label-free-detection","display_name":"label-free detection","score":0.7879999876022339},{"id":"https://openalex.org/keywords/hcc1806","display_name":"HCC1806","score":0.8420000076293945},{"id":"https://openalex.org/keywords/mda-mb-231-cells","display_name":"MDA-MB-231 cells","score":0.9580000042915344}],"concepts":[{"id":"https://openalex.org/C162602672","wikidata":"https://www.wikidata.org/wiki/Q2695129","display_name":"Molecularly imprinted polymer","level":4,"score":0.7979999780654907},{"id":"https://openalex.org/C2777230088","wikidata":"https://www.wikidata.org/wiki/Q864426","display_name":"Biocompatibility","level":2,"score":0.765500009059906},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5609999895095825},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.5570999979972839},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.5228999853134155},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5009999871253967},{"id":"https://openalex.org/C44228677","wikidata":"https://www.wikidata.org/wiki/Q181898","display_name":"Polymerization","level":3,"score":0.46299999952316284},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.46160000562667847},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.44369998574256897},{"id":"https://openalex.org/C39442485","wikidata":"https://www.wikidata.org/wiki/Q608768","display_name":"Molecular imprinting","level":4,"score":0.4153999984264374},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.41179999709129333},{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.3953999876976013},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3831000030040741},{"id":"https://openalex.org/C194232370","wikidata":"https://www.wikidata.org/wiki/Q162","display_name":"Optical fiber","level":2,"score":0.38029998540878296},{"id":"https://openalex.org/C2994423619","wikidata":"https://www.wikidata.org/wiki/Q9103","display_name":"Human breast","level":4,"score":0.3630000054836273},{"id":"https://openalex.org/C118792377","wikidata":"https://www.wikidata.org/wiki/Q108584245","display_name":"Selectivity","level":3,"score":0.34880000352859497},{"id":"https://openalex.org/C119128265","wikidata":"https://www.wikidata.org/wiki/Q900165","display_name":"Detection limit","level":2,"score":0.34389999508857727},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3005000054836273},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.27379998564720154},{"id":"https://openalex.org/C145018004","wikidata":"https://www.wikidata.org/wiki/Q4985944","display_name":"Buffer (optical fiber)","level":2,"score":0.273499995470047},{"id":"https://openalex.org/C61238886","wikidata":"https://www.wikidata.org/wiki/Q5121689","display_name":"Circulating tumor cell","level":4,"score":0.27309998869895935},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.27129998803138733},{"id":"https://openalex.org/C2985322473","wikidata":"https://www.wikidata.org/wiki/Q3044843","display_name":"Cancer detection","level":3,"score":0.2667999863624573}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.63946/onmt/19288","doi":"https://doi.org/10.63946/onmt/19288","is_oa":false,"landing_page_url":"https://doi.org/10.63946/onmt/19288","pdf_url":null,"source":{"id":"https://openalex.org/S5407052920","display_name":"Oncology Nuclear Medicine and Transplantology","issn_l":"3105-8760","issn":["3105-8760"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncology, Nuclear Medicine and Transplantology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6240000128746033,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7213667392","https://openalex.org/W7198199022","https://openalex.org/W4313490696","https://openalex.org/W4401705059","https://openalex.org/W7221552440","https://openalex.org/W2996773935","https://openalex.org/W4387631792","https://openalex.org/W2068694244","https://openalex.org/W4417054947","https://openalex.org/W3126491513"],"abstract_inverted_index":{"Introduction:":[0],"The":[1,51,187],"study":[2],"of":[3,11,30,54,62,115,162],"triple-negative":[4],"breast":[5],"cancer":[6,35,142],"cells":[7],"detection":[8,37,146,213],"is":[9,38,57],"one":[10],"the":[12,31,48,60,87,90,120,148,176,211],"important":[13],"research":[14],"fields":[15],"in":[16,113],"modern":[17],"biomedical":[18],"engineering,":[19],"due":[20],"to":[21],"its":[22],"aggressive":[23],"behavior":[24],"and":[25,72,98,140,157,175,185,196,202],"limited":[26],"targeting":[27],"options.":[28],"One":[29],"promising":[32],"methods":[33],"for":[34,199,207],"cell":[36,77,143,173],"using":[39,168],"Molecularly":[40],"Imprinted":[41],"Polymers":[42],"(MIPs)":[43],"with":[44,69,132,138],"polydopamine":[45],"(PDA)":[46],"as":[47,64],"primary":[49],"polymer.":[50],"main":[52],"idea":[53],"this":[55,81],"combination":[56],"based":[58],"on":[59,86],"properties":[61],"dopamine,":[63],"it":[65],"shows":[66,92,192],"good":[67],"compatibility":[68],"cells,":[70],"biomimicry,":[71],"biodegradability.":[73],"By":[74],"creating":[75],"specific":[76],"recognition":[78],"cavities":[79],"within":[80],"PDA-based":[82],"MIP":[83],"layer":[84],"directly":[85],"fiber":[88,190],"surface,":[89],"platform":[91],"high":[93],"selectivity":[94],"level":[95],"performance.":[96],"Methods":[97],"Materials:":[99],"Using":[100],"bulk":[101],"imprinting":[102],"strategy,":[103],"dopamine":[104],"was":[105,112,178],"polymerized":[106],"under":[107],"alkaline":[108],"conditions,":[109],"where":[110],"pH":[111],"range":[114],"8.0-9.0.":[116],"For":[117],"control":[118],"group,":[119],"non-imprinted":[121],"polymers":[122],"(NIPs)":[123],"were":[124,136,151,165],"prepared":[125],"by":[126,167],"mixing":[127],"phosphate":[128],"buffer":[129],"solution":[130],"(PBS)":[131],"PDA,":[133],"while":[134],"MIPs":[135],"functionalized":[137],"HCC1806":[139],"MDA-MB231":[141],"lines.":[144],"During":[145],"process,":[147],"response":[149],"groups":[150,164],"divided":[152],"into":[153],"two":[154],"categories:":[155],"target":[156],"cross":[158],"groups.":[159],"Optical":[160],"responses":[161],"these":[163],"determined":[166],"fiber-optic":[169],"interrogator":[170],"at":[171],"different":[172],"concentrations":[174],"morphology":[177],"evaluated":[179],"via":[180],"scanning":[181],"electron":[182],"microscopy.":[183],"Results":[184],"Conclusion:":[186],"provided":[188],"optical":[189],"technology":[191,201],"great":[193,205],"detection,":[194],"stability,":[195],"biocompatibility":[197],"levels":[198],"novel":[200],"has":[203],"a":[204],"potential":[206],"further":[208],"development":[209],"towards":[210],"label-free":[212],"platforms\u2019":[214],"integration.":[215]},"counts_by_year":[],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2026-09-20T00:00:00"}