{"id":"https://openalex.org/W7213550606","doi":"https://doi.org/10.7554/elife.109394.2","title":"Endosome-associated Rab GTPases control distinct aspects of neural circuit assembly","display_name":"Endosome-associated Rab GTPases control distinct aspects of neural circuit assembly","publication_year":2026,"publication_date":"2026-09-18","ids":{"openalex":"https://openalex.org/W7213550606","doi":"https://doi.org/10.7554/elife.109394.2"},"language":"en","primary_location":{"id":"doi:10.7554/elife.109394.2","doi":"https://doi.org/10.7554/elife.109394.2","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.109394.2","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"eLife","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.7554/elife.109394.2","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5146036954","display_name":"Katie X. Dong","orcid":"https://orcid.org/0009-0003-0613-7454","observed_orcids":["https://orcid.org/0009-0003-0613-7454"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katie X Dong","raw_affiliation_strings":["Department of Biology, Howard Hughes Medical Institute, Stanford University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Howard Hughes Medical Institute, Stanford University","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100732244","display_name":"Yanbo Zhang","orcid":"https://orcid.org/0000-0002-2421-157X","observed_orcids":["https://orcid.org/0000-0002-2421-157X","https://orcid.org/0009-0000-1092-8150"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yanbo Zhang","raw_affiliation_strings":["Department of Biology, Howard Hughes Medical Institute, Stanford University"],"raw_orcid":"https://orcid.org/0009-0000-1092-8150","affiliations":[{"raw_affiliation_string":"Department of Biology, Howard Hughes Medical Institute, Stanford University","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084640985","display_name":"Hui Ji","orcid":"https://orcid.org/0000-0001-5432-8157","observed_orcids":["https://orcid.org/0000-0001-5432-8157"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hui Ji","raw_affiliation_strings":["Department of Biology, Howard Hughes Medical Institute, Stanford University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Howard Hughes Medical Institute, Stanford University","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088213051","display_name":"David J. Luginbuhl","orcid":"https://orcid.org/0000-0002-2142-780X","observed_orcids":["https://orcid.org/0000-0002-2142-780X"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David J Luginbuhl","raw_affiliation_strings":["Department of Biology, Howard Hughes Medical Institute, Stanford University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Howard Hughes Medical Institute, Stanford University","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068143983","display_name":"Liqun Luo","orcid":"https://orcid.org/0000-0001-5467-9264","observed_orcids":["https://orcid.org/0000-0001-5467-9264"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Liqun Luo","raw_affiliation_strings":["Department of Biology, Howard Hughes Medical Institute, Stanford University"],"raw_orcid":"https://orcid.org/0000-0001-5467-9264","affiliations":[{"raw_affiliation_string":"Department of Biology, Howard Hughes Medical Institute, Stanford University","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I97018004"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048060413","display_name":"Colleen N. McLaughlin","orcid":"https://orcid.org/0000-0002-7518-8920","observed_orcids":["https://orcid.org/0000-0002-7518-8920"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Colleen N McLaughlin","raw_affiliation_strings":["Department of Biology, Howard Hughes Medical Institute, Stanford University"],"raw_orcid":"https://orcid.org/0000-0002-7518-8920","affiliations":[{"raw_affiliation_string":"Department of Biology, Howard Hughes Medical Institute, Stanford University","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":2500},"apc_paid":{"value":3000,"currency":"USD","value_usd":2500},"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rab-gtpases","display_name":"Rab GTPases","score":0.9380000233650208},{"id":"https://openalex.org/keywords/rab5","display_name":"Rab5","score":0.7590000033378601},{"id":"https://openalex.org/keywords/rab11","display_name":"Rab11","score":1.0},{"id":"https://openalex.org/keywords/endosomes","display_name":"endosomes","score":0.6700000166893005},{"id":"https://openalex.org/keywords/endocytosis","display_name":"endocytosis","score":0.8069999814033508},{"id":"https://openalex.org/keywords/neural-circuit-assembly","display_name":"neural circuit assembly","score":0.7839999794960022},{"id":"https://openalex.org/keywords/receptor-trafficking","display_name":"receptor trafficking","score":0.5460000038146973},{"id":"https://openalex.org/keywords/recycling-endosomes","display_name":"recycling endosomes","score":0.8379999995231628},{"id":"https://openalex.org/keywords/early-endosomes","display_name":"early endosomes","score":0.7260000109672546},{"id":"https://openalex.org/keywords/late-endosomes","display_name":"late endosomes","score":0.9169999957084656},{"id":"https://openalex.org/keywords/lysosomal-degradation","display_name":"lysosomal degradation","score":0.8019999861717224},{"id":"https://openalex.org/keywords/cell-surface-receptors","display_name":"cell surface receptors","score":0.6800000071525574},{"id":"https://openalex.org/keywords/neuronal-development","display_name":"neuronal development","score":0.6570000052452087}],"concepts":[{"id":"https://openalex.org/C156728348","wikidata":"https://www.wikidata.org/wiki/Q416778","display_name":"Rab","level":3,"score":0.947700023651123},{"id":"https://openalex.org/C102747710","wikidata":"https://www.wikidata.org/wiki/Q824237","display_name":"Endosome","level":3,"score":0.8647000193595886},{"id":"https://openalex.org/C79747257","wikidata":"https://www.wikidata.org/wiki/Q189814","display_name":"Endocytic cycle","level":4,"score":0.8396000266075134},{"id":"https://openalex.org/C207332259","wikidata":"https://www.wikidata.org/wiki/Q769143","display_name":"GTPase","level":2,"score":0.7261000275611877},{"id":"https://openalex.org/C28005876","wikidata":"https://www.wikidata.org/wiki/Q189814","display_name":"Endocytosis","level":3,"score":0.7110000252723694},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6805999875068665},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.585099995136261},{"id":"https://openalex.org/C145458877","wikidata":"https://www.wikidata.org/wiki/Q7317044","display_name":"Retromer","level":4,"score":0.4603999853134155},{"id":"https://openalex.org/C2780298669","wikidata":"https://www.wikidata.org/wiki/Q415071","display_name":"Small GTPase","level":3,"score":0.4357999861240387},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3880999982357025},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.3831999897956848},{"id":"https://openalex.org/C191597335","wikidata":"https://www.wikidata.org/wiki/Q4996475","display_name":"Bulk endocytosis","level":5,"score":0.34310001134872437},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.33500000834465027},{"id":"https://openalex.org/C118403218","wikidata":"https://www.wikidata.org/wiki/Q43283","display_name":"Biological neural network","level":2,"score":0.323199987411499},{"id":"https://openalex.org/C69125201","wikidata":"https://www.wikidata.org/wiki/Q2034716","display_name":"Axon guidance","level":3,"score":0.2824000120162964},{"id":"https://openalex.org/C461258","wikidata":"https://www.wikidata.org/wiki/Q1345738","display_name":"Neural development","level":3,"score":0.27799999713897705},{"id":"https://openalex.org/C545706735","wikidata":"https://www.wikidata.org/wiki/Q9404","display_name":"Nervous system","level":2,"score":0.2743000090122223},{"id":"https://openalex.org/C2778794669","wikidata":"https://www.wikidata.org/wiki/Q43054","display_name":"Neuron","level":2,"score":0.27410000562667847},{"id":"https://openalex.org/C127445978","wikidata":"https://www.wikidata.org/wiki/Q187181","display_name":"Synapse","level":2,"score":0.262800008058548},{"id":"https://openalex.org/C57581600","wikidata":"https://www.wikidata.org/wiki/Q2449730","display_name":"Transport protein","level":2,"score":0.251800000667572},{"id":"https://openalex.org/C203635412","wikidata":"https://www.wikidata.org/wiki/Q17007432","display_name":"Compartment (ship)","level":2,"score":0.2517000138759613}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.7554/elife.109394.2","doi":"https://doi.org/10.7554/elife.109394.2","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.109394.2","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"eLife","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.7554/elife.109394.2","doi":"https://doi.org/10.7554/elife.109394.2","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.109394.2","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"eLife","raw_type":"posted-content"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":118,"referenced_works":["https://openalex.org/W1494304190","https://openalex.org/W1499176799","https://openalex.org/W1516244929","https://openalex.org/W1595083713","https://openalex.org/W1606338704","https://openalex.org/W1630481045","https://openalex.org/W1908692741","https://openalex.org/W1967182910","https://openalex.org/W1970550888","https://openalex.org/W1970661950","https://openalex.org/W1971725639","https://openalex.org/W1974223005","https://openalex.org/W1975652746","https://openalex.org/W1980142948","https://openalex.org/W1985383802","https://openalex.org/W2005574904","https://openalex.org/W2006229889","https://openalex.org/W2006523246","https://openalex.org/W2007797957","https://openalex.org/W2008163597","https://openalex.org/W2012560446","https://openalex.org/W2012756610","https://openalex.org/W2018979418","https://openalex.org/W2019104271","https://openalex.org/W2019417594","https://openalex.org/W2022954501","https://openalex.org/W2028648894","https://openalex.org/W2044430292","https://openalex.org/W2046133662","https://openalex.org/W2054735667","https://openalex.org/W2055804746","https://openalex.org/W2059346525","https://openalex.org/W2060653523","https://openalex.org/W2062956758","https://openalex.org/W2065378127","https://openalex.org/W2073397397","https://openalex.org/W2074189105","https://openalex.org/W2075433744","https://openalex.org/W2077904579","https://openalex.org/W2082379606","https://openalex.org/W2089778398","https://openalex.org/W2092098765","https://openalex.org/W2092365132","https://openalex.org/W2093079184","https://openalex.org/W2094150528","https://openalex.org/W2100270425","https://openalex.org/W2101235918","https://openalex.org/W2108175824","https://openalex.org/W2110643873","https://openalex.org/W2113451695","https://openalex.org/W2115354701","https://openalex.org/W2118398316","https://openalex.org/W2119462245","https://openalex.org/W2128573075","https://openalex.org/W2135823825","https://openalex.org/W2138667327","https://openalex.org/W2142395008","https://openalex.org/W2142667969","https://openalex.org/W2144875895","https://openalex.org/W2145206503","https://openalex.org/W2146015738","https://openalex.org/W2148579087","https://openalex.org/W2151988921","https://openalex.org/W2152255315","https://openalex.org/W2157071511","https://openalex.org/W2158976454","https://openalex.org/W2159935247","https://openalex.org/W2160777888","https://openalex.org/W2160874195","https://openalex.org/W2161932769","https://openalex.org/W2162207411","https://openalex.org/W2166135064","https://openalex.org/W2166155213","https://openalex.org/W2191269904","https://openalex.org/W2257867940","https://openalex.org/W2282729595","https://openalex.org/W2342538530","https://openalex.org/W2512927671","https://openalex.org/W2560573672","https://openalex.org/W2560652101","https://openalex.org/W2750917058","https://openalex.org/W2761788149","https://openalex.org/W2765589479","https://openalex.org/W2802487502","https://openalex.org/W2810811018","https://openalex.org/W2888750404","https://openalex.org/W2890393959","https://openalex.org/W2904796164","https://openalex.org/W2907024869","https://openalex.org/W2913956170","https://openalex.org/W2925756480","https://openalex.org/W2938381809","https://openalex.org/W2959845099","https://openalex.org/W2964053234","https://openalex.org/W3033287222","https://openalex.org/W3090467204","https://openalex.org/W3119698738","https://openalex.org/W3122145821","https://openalex.org/W3127332899","https://openalex.org/W3129437997","https://openalex.org/W3135860616","https://openalex.org/W3148916402","https://openalex.org/W3153983503","https://openalex.org/W3159327105","https://openalex.org/W3163958595","https://openalex.org/W4213131142","https://openalex.org/W4214550233","https://openalex.org/W4223420927","https://openalex.org/W4223436940","https://openalex.org/W4292122029","https://openalex.org/W4306175472","https://openalex.org/W4313648337","https://openalex.org/W4317740379","https://openalex.org/W4361190358","https://openalex.org/W4402204048","https://openalex.org/W4408301626","https://openalex.org/W7099323020","https://openalex.org/W7135124598"],"related_works":["https://openalex.org/W6964505022","https://openalex.org/W2149491013","https://openalex.org/W4292170473","https://openalex.org/W2019104271","https://openalex.org/W2011189824","https://openalex.org/W1881270362","https://openalex.org/W3111898646","https://openalex.org/W2402262635","https://openalex.org/W2160775987","https://openalex.org/W1976820777"],"abstract_inverted_index":{"Neural":[0],"circuit":[1,55,82,112],"assembly":[2,83],"relies":[3],"on":[4],"the":[5,34,67,101,118],"precise":[6],"regulation":[7],"of":[8,69,81,104,123],"cell-surface":[9,35],"receptors":[10,45],"that":[11,89],"mediate":[12],"signaling":[13],"and":[14,20,24,75,91,95,108,121],"adhesion.":[15],"Endocytosis":[16],"controls":[17],"receptor":[18],"activity":[19],"availability":[21],"by":[22],"internalizing":[23],"routing":[25],"proteins":[26],"through":[27],"two":[28],"main":[29],"pathways:":[30],"recycling":[31,76,109],"back":[32],"to":[33,38,54,72,128,143],"or":[36],"delivery":[37],"lysosomes":[39],"for":[40],"degradation.":[41],"Rab":[42],"GTPases":[43],"direct":[44],"into":[46],"these":[47],"distinct":[48,97,137],"pathways,":[49],"but":[50],"their":[51],"specific":[52,124],"contributions":[53],"formation":[56],"remain":[57],"opaque.":[58],"Using":[59],"clonal":[60],"analyses":[61],"with":[62],"null":[63],"alleles,":[64],"we":[65],"dissected":[66],"roles":[68,103],"Rab-mediated":[70],"trafficking":[71,131,139],"early,":[73],"late,":[74],"endosomes":[77],"across":[78],"multiple":[79],"stages":[80],"in":[84,111],"vivo.":[85],"Our":[86,133],"approach":[87],"revealed":[88],"Rab5":[90],"Rab11":[92],"regulate":[93],"extensive":[94],"largely":[96],"developmental":[98],"events,":[99],"highlighting":[100],"pivotal":[102],"early":[105],"endosome":[106],"sorting":[107],"pathways":[110],"assembly.":[113],"As":[114],"neurons":[115],"mature,":[116],"both":[117],"spatial":[119],"distribution":[120],"abundance":[122],"endocytic":[125],"compartments":[126],"change":[127],"reflect":[129],"evolving":[130],"demands.":[132],"findings":[134],"underscore":[135],"how":[136],"post-endocytic":[138],"fates":[140],"are":[141],"necessary":[142],"build":[144],"neural":[145],"circuits.":[146]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-09-18T00:00:00"}
