{"id":"https://openalex.org/W7213535222","doi":"https://doi.org/10.64898/2026.09.17.752289","title":"A bacterial nucleolus for cold adaptation","display_name":"A bacterial nucleolus for cold adaptation","publication_year":2026,"publication_date":"2026-09-18","ids":{"openalex":"https://openalex.org/W7213535222","doi":"https://doi.org/10.64898/2026.09.17.752289"},"language":"en","primary_location":{"id":"doi:10.64898/2026.09.17.752289","doi":"https://doi.org/10.64898/2026.09.17.752289","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.17.752289","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/09/18/2026.09.17.752289.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2026/09/18/2026.09.17.752289.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027502745","display_name":"Michelle Jennifer Gut","orcid":"https://orcid.org/0000-0002-8921-8529","observed_orcids":["https://orcid.org/0000-0002-8921-8529"]},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Michelle J. Gut","raw_affiliation_strings":["Biozentrum, University of Basel, Basel, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-8921-8529","affiliations":[{"raw_affiliation_string":"Biozentrum, University of Basel, Basel, Switzerland","institution_ids":["https://openalex.org/I1850255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080621727","display_name":"Kerstin D\u00f6rner","orcid":"https://orcid.org/0000-0003-2541-0930","observed_orcids":["https://orcid.org/0000-0003-2541-0930"]},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"K. D\u00f6rner","raw_affiliation_strings":["Biozentrum, University of Basel, Basel, Switzerland"],"raw_orcid":"https://orcid.org/0000-0003-2541-0930","affiliations":[{"raw_affiliation_string":"Biozentrum, University of Basel, Basel, Switzerland","institution_ids":["https://openalex.org/I1850255"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Sebastian Abegg","orcid":"https://orcid.org/0009-0003-7378-1450","observed_orcids":["https://orcid.org/0009-0003-7378-1450"]},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]},{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Sebastian Abegg","raw_affiliation_strings":["Biozentrum, University of Basel, Basel, Switzerland","ETH Zurich, Zurich, Switzerland"],"raw_orcid":"https://orcid.org/0009-0003-7378-1450","affiliations":[{"raw_affiliation_string":"Biozentrum, University of Basel, Basel, Switzerland","institution_ids":["https://openalex.org/I1850255"]},{"raw_affiliation_string":"ETH Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I35440088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025048436","display_name":"Nusrat S. Qureshi","orcid":"https://orcid.org/0000-0002-5753-5984","observed_orcids":["https://orcid.org/0000-0002-5753-5984"]},"institutions":[{"id":"https://openalex.org/I4210138560","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/03mstc592","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560"]},{"id":"https://openalex.org/I4210153543","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/050589e39","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560","https://openalex.org/I4210153543"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Nusrat S. Qureshi","raw_affiliation_strings":["Molecular Systems Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany"],"raw_orcid":"https://orcid.org/0000-0002-5753-5984","affiliations":[{"raw_affiliation_string":"Molecular Systems Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany","institution_ids":["https://openalex.org/I4210138560","https://openalex.org/I4210153543"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068985756","display_name":"Kausthubh Ramachandran","orcid":"https://orcid.org/0000-0002-6221-8166","observed_orcids":["https://orcid.org/0000-0002-6221-8166"]},"institutions":[{"id":"https://openalex.org/I51601045","display_name":"University of Bath","ror":"https://ror.org/002h8g185","country_code":"GB","type":"education","lineage":["https://openalex.org/I51601045"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kausthubh Ramachandran","raw_affiliation_strings":["Centre for Evolution, Department of Life Sciences, University of Bath, Bath, UK"],"raw_orcid":"https://orcid.org/0000-0002-6221-8166","affiliations":[{"raw_affiliation_string":"Centre for Evolution, Department of Life Sciences, University of Bath, Bath, UK","institution_ids":["https://openalex.org/I51601045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056949320","display_name":"Alexia Ferrand","orcid":"https://orcid.org/0000-0001-7292-1325","observed_orcids":["https://orcid.org/0000-0001-7292-1325"]},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Alexia Ferrand","raw_affiliation_strings":["Biozentrum, University of Basel, Basel, Switzerland"],"raw_orcid":"https://orcid.org/0000-0001-7292-1325","affiliations":[{"raw_affiliation_string":"Biozentrum, University of Basel, Basel, Switzerland","institution_ids":["https://openalex.org/I1850255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087874713","display_name":"Alexander Schmidt","orcid":"https://orcid.org/0000-0002-3149-2381","observed_orcids":["https://orcid.org/0000-0002-3149-2381"]},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Alexander Schmidt","raw_affiliation_strings":["Biozentrum, University of Basel, Basel, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-3149-2381","affiliations":[{"raw_affiliation_string":"Biozentrum, University of Basel, Basel, Switzerland","institution_ids":["https://openalex.org/I1850255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077622955","display_name":"R\u016bta Prakapait\u0117","orcid":"https://orcid.org/0000-0002-5741-8622","observed_orcids":["https://orcid.org/0000-0002-5741-8622"]},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]},{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Ruta Prakapaite","raw_affiliation_strings":["Biozentrum, University of Basel, Basel, Switzerland","ETH Zurich, Zurich, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-5741-8622","affiliations":[{"raw_affiliation_string":"Biozentrum, University of Basel, Basel, Switzerland","institution_ids":["https://openalex.org/I1850255"]},{"raw_affiliation_string":"ETH Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I35440088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101579525","display_name":"Tom A. Williams","orcid":"https://orcid.org/0000-0003-1072-0223","observed_orcids":["https://orcid.org/0000-0003-1072-0223"]},"institutions":[{"id":"https://openalex.org/I51601045","display_name":"University of Bath","ror":"https://ror.org/002h8g185","country_code":"GB","type":"education","lineage":["https://openalex.org/I51601045"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tom A. Williams","raw_affiliation_strings":["Centre for Evolution, Department of Life Sciences, University of Bath, Bath, UK"],"raw_orcid":"https://orcid.org/0000-0003-1072-0223","affiliations":[{"raw_affiliation_string":"Centre for Evolution, Department of Life Sciences, University of Bath, Bath, UK","institution_ids":["https://openalex.org/I51601045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072324762","display_name":"Olivier Duss","orcid":"https://orcid.org/0000-0003-0929-3471","observed_orcids":["https://orcid.org/0000-0003-0929-3471"]},"institutions":[{"id":"https://openalex.org/I4210138560","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/03mstc592","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560"]},{"id":"https://openalex.org/I4210153543","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/050589e39","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560","https://openalex.org/I4210153543"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Olivier Duss","raw_affiliation_strings":["Molecular Systems Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany"],"raw_orcid":"https://orcid.org/0000-0003-0929-3471","affiliations":[{"raw_affiliation_string":"Molecular Systems Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany","institution_ids":["https://openalex.org/I4210138560","https://openalex.org/I4210153543"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049295836","display_name":"Maria Hondele","orcid":"https://orcid.org/0000-0002-2733-2561","observed_orcids":["https://orcid.org/0000-0002-2733-2561"]},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Maria Hondele","raw_affiliation_strings":["Biozentrum, University of Basel, Basel, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-2733-2561","affiliations":[{"raw_affiliation_string":"Biozentrum, University of Basel, Basel, Switzerland","institution_ids":["https://openalex.org/I1850255"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5049295836"],"corresponding_institution_ids":["https://openalex.org/I1850255"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9164999723434448,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9164999723434448,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.04910000041127205,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.013199999928474426,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biomolecular-condensates","display_name":"biomolecular condensates","score":0.9449999928474426},{"id":"https://openalex.org/keywords/cold-adaptation","display_name":"cold adaptation","score":0.9559999704360962},{"id":"https://openalex.org/keywords/ribosome-biogenesis","display_name":"ribosome biogenesis","score":0.9549999833106995},{"id":"https://openalex.org/keywords/csda","display_name":"CsdA","score":0.7829999923706055},{"id":"https://openalex.org/keywords/rdna-loci","display_name":"rDNA loci","score":0.8090000152587891},{"id":"https://openalex.org/keywords/rrna-transcription","display_name":"rRNA transcription","score":0.8330000042915344},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.8629999756813049},{"id":"https://openalex.org/keywords/compartmentalization","display_name":"compartmentalization","score":0.8149999976158142},{"id":"https://openalex.org/keywords/rna-secondary-structure","display_name":"RNA secondary structure","score":0.7799999713897705},{"id":"https://openalex.org/keywords/ribosome-maturation","display_name":"ribosome maturation","score":0.7940000295639038}],"concepts":[{"id":"https://openalex.org/C2779419633","wikidata":"https://www.wikidata.org/wiki/Q7322423","display_name":"Ribosome biogenesis","level":5,"score":0.8476999998092651},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7010999917984009},{"id":"https://openalex.org/C183873130","wikidata":"https://www.wikidata.org/wiki/Q30869","display_name":"Nucleolus","level":3,"score":0.6924999952316284},{"id":"https://openalex.org/C88478588","wikidata":"https://www.wikidata.org/wiki/Q42244","display_name":"Ribosome","level":4,"score":0.6807000041007996},{"id":"https://openalex.org/C67905577","wikidata":"https://www.wikidata.org/wiki/Q215980","display_name":"Ribosomal RNA","level":3,"score":0.6065999865531921},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5139999985694885},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.4837999939918518},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.47679999470710754},{"id":"https://openalex.org/C2991743866","wikidata":"https://www.wikidata.org/wiki/Q417379","display_name":"Rna processing","level":4,"score":0.43160000443458557},{"id":"https://openalex.org/C139807058","wikidata":"https://www.wikidata.org/wiki/Q352374","display_name":"Adaptation (eye)","level":2,"score":0.41990000009536743},{"id":"https://openalex.org/C131934819","wikidata":"https://www.wikidata.org/wiki/Q135390","display_name":"Biogenesis","level":3,"score":0.4165000021457672},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.40459999442100525},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.36480000615119934},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.3540000021457672},{"id":"https://openalex.org/C149364088","wikidata":"https://www.wikidata.org/wiki/Q185917","display_name":"Translation (biology)","level":4,"score":0.3431999981403351},{"id":"https://openalex.org/C3675279","wikidata":"https://www.wikidata.org/wiki/Q211935","display_name":"Protein biosynthesis","level":2,"score":0.34200000762939453},{"id":"https://openalex.org/C38062823","wikidata":"https://www.wikidata.org/wiki/Q3408228","display_name":"Ribosomal protein","level":5,"score":0.33970001339912415},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.32190001010894775},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.296999990940094},{"id":"https://openalex.org/C26261996","wikidata":"https://www.wikidata.org/wiki/Q2382392","display_name":"Bacterial transcription","level":5,"score":0.27810001373291016},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.2694999873638153},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.2646999955177307},{"id":"https://openalex.org/C182325514","wikidata":"https://www.wikidata.org/wiki/Q7322425","display_name":"Ribosome profiling","level":5,"score":0.2623000144958496},{"id":"https://openalex.org/C4718897","wikidata":"https://www.wikidata.org/wiki/Q5408698","display_name":"Eukaryotic translation","level":5,"score":0.25450000166893005}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.09.17.752289","doi":"https://doi.org/10.64898/2026.09.17.752289","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.17.752289","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/09/18/2026.09.17.752289.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.64898/2026.09.17.752289","doi":"https://doi.org/10.64898/2026.09.17.752289","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.17.752289","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/09/18/2026.09.17.752289.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2669100578","display_name":"Microbial mercury methylation: a detoxifying defense or an antimicrobial advantage?","funder_award_id":"BB/Z51696X/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320310466","display_name":"Universit\u00e4t Basel","ror":"https://ror.org/02s6k3f65"},{"id":"https://openalex.org/F4320314023","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/050589e39"},{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7213535222.pdf","grobid_xml":"https://content.openalex.org/works/W7213535222.grobid-xml"},"referenced_works_count":97,"referenced_works":["https://openalex.org/W1562839240","https://openalex.org/W1595340441","https://openalex.org/W1717833723","https://openalex.org/W1872598604","https://openalex.org/W1905117713","https://openalex.org/W1974694769","https://openalex.org/W2003409413","https://openalex.org/W2012313889","https://openalex.org/W2013410948","https://openalex.org/W2015159529","https://openalex.org/W2021425188","https://openalex.org/W2031166525","https://openalex.org/W2031611770","https://openalex.org/W2036116609","https://openalex.org/W2037586865","https://openalex.org/W2045704444","https://openalex.org/W2049681307","https://openalex.org/W2109702558","https://openalex.org/W2112186461","https://openalex.org/W2114525641","https://openalex.org/W2115888213","https://openalex.org/W2116137883","https://openalex.org/W2121366176","https://openalex.org/W2125655241","https://openalex.org/W2135621733","https://openalex.org/W2139146574","https://openalex.org/W2145029585","https://openalex.org/W2146923856","https://openalex.org/W2160276669","https://openalex.org/W2160378127","https://openalex.org/W2166387637","https://openalex.org/W2167241647","https://openalex.org/W2169508088","https://openalex.org/W2191824721","https://openalex.org/W2330547698","https://openalex.org/W2416002786","https://openalex.org/W2527809167","https://openalex.org/W2550575345","https://openalex.org/W2563613798","https://openalex.org/W2744971808","https://openalex.org/W2766641567","https://openalex.org/W2767002967","https://openalex.org/W2900884817","https://openalex.org/W2949078846","https://openalex.org/W2951464304","https://openalex.org/W2969343565","https://openalex.org/W2991162729","https://openalex.org/W2991495225","https://openalex.org/W3000736974","https://openalex.org/W3003257820","https://openalex.org/W3005957649","https://openalex.org/W3019706413","https://openalex.org/W3019766797","https://openalex.org/W3035965352","https://openalex.org/W3043530209","https://openalex.org/W3045908771","https://openalex.org/W3111521801","https://openalex.org/W3152686838","https://openalex.org/W3176217806","https://openalex.org/W3196691244","https://openalex.org/W3197335476","https://openalex.org/W3207327262","https://openalex.org/W4200243080","https://openalex.org/W4224865640","https://openalex.org/W4239125810","https://openalex.org/W4281490610","https://openalex.org/W4294387621","https://openalex.org/W4304778228","https://openalex.org/W4308343438","https://openalex.org/W4324304881","https://openalex.org/W4362506517","https://openalex.org/W4385302529","https://openalex.org/W4385711740","https://openalex.org/W4386193823","https://openalex.org/W4386498559","https://openalex.org/W4387093159","https://openalex.org/W4388759168","https://openalex.org/W4390608966","https://openalex.org/W4392005577","https://openalex.org/W4393118060","https://openalex.org/W4394689081","https://openalex.org/W4404225840","https://openalex.org/W4405801287","https://openalex.org/W4407762541","https://openalex.org/W4408855740","https://openalex.org/W4409559246","https://openalex.org/W4409605660","https://openalex.org/W4409988818","https://openalex.org/W4410706040","https://openalex.org/W4411100303","https://openalex.org/W4411932253","https://openalex.org/W4412600599","https://openalex.org/W4416416816","https://openalex.org/W7117979310","https://openalex.org/W7139960558","https://openalex.org/W7160408120","https://openalex.org/W7161736532"],"related_works":["https://openalex.org/W2289311086","https://openalex.org/W2263094014","https://openalex.org/W7062228594","https://openalex.org/W4414609950","https://openalex.org/W3152686838","https://openalex.org/W7167340469","https://openalex.org/W2802615574","https://openalex.org/W4308104138","https://openalex.org/W59874115","https://openalex.org/W2768674109"],"abstract_inverted_index":{"Abstract":[0],"Compartmentalisation":[1],"enables":[2],"cells":[3],"to":[4,30,52,112,127],"spatially":[5,53,108],"organise":[6,54],"essential":[7,184],"biochemical":[8,185],"processes.":[9,186],"This":[10,77],"is":[11,96],"exemplified":[12],"by":[13],"the":[14,19,71,79,101,166,181],"eukaryotic":[15],"nucleolus,":[16],"which":[17,61],"concentrates":[18],"machinery":[20,104],"for":[21],"ribosome":[22,57,121,163],"biogenesis":[23,164],"1,2":[24],".":[25,76],"Bacteria":[26],"are":[27],"generally":[28],"thought":[29],"lack":[31],"an":[32],"equivalent":[33],"compartment.":[34],"Here":[35],"we":[36],"discover":[37],"a":[38,158],"nucleolus-like":[39],"condensate":[40,88,134],"in":[41],"Escherichia":[42],"coli":[43],"that":[44,139,172],"emerges":[45],"at":[46,90],"rDNA":[47,91],"loci":[48,92],"during":[49],"cold":[50,128],"adaptation":[51,126],"and":[55,105,115,123,170],"promote":[56],"biogenesis.":[58],"Low":[59],"temperatures,":[60],"stabilise":[62],"RNA":[63,142],"secondary":[64],"structures":[65],"3\u20138":[66],",":[67],"induce":[68],"accumulation":[69],"of":[70,133,162,168,183],"RNA-remodelling":[72],"enzyme":[73],"CsdA":[74,81,98,118],"9,10":[75],"raises":[78],"cellular":[80],"concentration":[82],"above":[83],"its":[84],"condensation":[85,119],"threshold,":[86],"driving":[87],"formation":[89],"when":[93,177],"rRNA":[94,102,110],"transcription":[95,103],"active.":[97],"compartments":[99],"enrich":[100],"ribosome-biogenesis":[106],"factors,":[107],"linking":[109],"synthesis":[111],"downstream":[113],"processing":[114],"assembly.":[116],"Disrupting":[117],"impairs":[120],"maturation":[122],"reduces":[124],"bacterial":[125,150],"temperature,":[129],"demonstrating":[130],"functional":[131],"importance":[132],"formation.":[135],"Comparative":[136],"genomics":[137],"suggests":[138],"analogous":[140],"condensate-forming":[141],"remodelling":[143],"enzymes":[144],"have":[145],"evolved":[146],"repeatedly":[147],"across":[148,165],"diverse":[149],"lineages.":[151],"Our":[152],"findings":[153],"establish":[154],"biomolecular":[155],"condensates":[156],"as":[157],"unifying":[159],"organisational":[160],"principle":[161],"tree":[167],"life":[169],"suggest":[171],"adaptive":[173],"compartmentalisation":[174],"can":[175],"emerge":[176],"environmental":[178],"conditions":[179],"challenge":[180],"efficiency":[182]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-09-18T00:00:00"}