{"id":"https://openalex.org/W7213534369","doi":"https://doi.org/10.2147/itt.s604318","title":"ACBP/DBI Neutralization Stimulates Anticancer Immune Responses by Upregulating Lamin A in T Cells","display_name":"ACBP/DBI Neutralization Stimulates Anticancer Immune Responses by Upregulating Lamin A in T Cells","publication_year":2026,"publication_date":"2026-09-01","ids":{"openalex":"https://openalex.org/W7213534369","doi":"https://doi.org/10.2147/itt.s604318","pmid":"https://pubmed.ncbi.nlm.nih.gov/42774966","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13596399"},"language":"en","primary_location":{"id":"doi:10.2147/itt.s604318","doi":"https://doi.org/10.2147/itt.s604318","is_oa":true,"landing_page_url":"https://doi.org/10.2147/itt.s604318","pdf_url":null,"source":{"id":"https://openalex.org/S4210174637","display_name":"ImmunoTargets and Therapy","issn_l":"2253-1556","issn":["2253-1556"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ImmunoTargets and Therapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.2147/itt.s604318","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101836522","display_name":"Sijing Li","orcid":"https://orcid.org/0009-0003-1535-6050","observed_orcids":["https://orcid.org/0009-0003-1535-6050"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210092322","display_name":"Centre de Recherche des Cordeliers","ror":"https://ror.org/00dmms154","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sijing Li","raw_affiliation_strings":["Team \"Metabolism, Cancer & Immunity\", Cordeliers Research Center, Inserm, Paris Cit\u00e9 University, Sorbonne University, Paris, 75006, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Team \"Metabolism, Cancer & Immunity\", Cordeliers Research Center, Inserm, Paris Cit\u00e9 University, Sorbonne University, Paris, 75006, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087974982","display_name":"Carlos L\u00f3pez-Ot\u0131\u0301n","orcid":"https://orcid.org/0000-0001-6964-1904","observed_orcids":["https://orcid.org/0000-0001-6964-1904"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210092322","display_name":"Centre de Recherche des Cordeliers","ror":"https://ror.org/00dmms154","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Carlos L\u00f3pez-Ot\u00edn","raw_affiliation_strings":["Team \"Metabolism, Cancer & Immunity\", Cordeliers Research Center, Inserm, Paris Cit\u00e9 University, Sorbonne University, Paris, 75006, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Team \"Metabolism, Cancer & Immunity\", Cordeliers Research Center, Inserm, Paris Cit\u00e9 University, Sorbonne University, Paris, 75006, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085340395","display_name":"Maria Chiara Maiuri","orcid":"https://orcid.org/0000-0001-9760-7674","observed_orcids":["https://orcid.org/0000-0001-9760-7674"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210092322","display_name":"Centre de Recherche des Cordeliers","ror":"https://ror.org/00dmms154","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]},{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["FR","IT"],"is_corresponding":false,"raw_author_name":"Maria Chiara Maiuri","raw_affiliation_strings":["Department of Molecular Medicine and Medical Biotechnologies, University of Naples Federico II, Naples, Italy","Team \"Metabolism, Cancer & Immunity\", Cordeliers Research Center, Inserm, Paris Cit\u00e9 University, Sorbonne University, Paris, 75006, France"],"raw_orcid":"https://orcid.org/0000-0001-9760-7674","affiliations":[{"raw_affiliation_string":"Department of Molecular Medicine and Medical Biotechnologies, University of Naples Federico II, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]},{"raw_affiliation_string":"Team \"Metabolism, Cancer & Immunity\", Cordeliers Research Center, Inserm, Paris Cit\u00e9 University, Sorbonne University, Paris, 75006, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077808010","display_name":"Isabelle Martins","orcid":"https://orcid.org/0000-0003-0885-613X","observed_orcids":["https://orcid.org/0000-0003-0885-613X"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210092322","display_name":"Centre de Recherche des Cordeliers","ror":"https://ror.org/00dmms154","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Isabelle Martins","raw_affiliation_strings":["Team \"Metabolism, Cancer & Immunity\", Cordeliers Research Center, Inserm, Paris Cit\u00e9 University, Sorbonne University, Paris, 75006, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Team \"Metabolism, Cancer & Immunity\", Cordeliers Research Center, Inserm, Paris Cit\u00e9 University, Sorbonne University, Paris, 75006, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075296559","display_name":"Guido Kroemer","orcid":"https://orcid.org/0000-0002-9334-4405","observed_orcids":["https://orcid.org/0000-0002-9334-4405"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I2801843802","display_name":"Institut Gustave Roussy","ror":"https://ror.org/0321g0743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801843802"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210092322","display_name":"Centre de Recherche des Cordeliers","ror":"https://ror.org/00dmms154","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210102325","display_name":"H\u00f4pital Europ\u00e9en Georges-Pompidou","ror":"https://ror.org/016vx5156","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102325","https://openalex.org/I4210120235"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Guido Kroemer","raw_affiliation_strings":["Department of Biology, Cancer Institute Paris CARPEM, European Hospital Georges Pompidou, AP-HP, Paris, France","Metabolomics and Cell Biology Platforms, Inserm, CNRS, Paris Saclay Saclay, Institute Gustave Roussy, Villejuif, France","Team \"Metabolism, Cancer & Immunity\", Cordeliers Research Center, Inserm, Paris Cit\u00e9 University, Sorbonne University, Paris, 75006, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Cancer Institute Paris CARPEM, European Hospital Georges Pompidou, AP-HP, Paris, France","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210102325"]},{"raw_affiliation_string":"Metabolomics and Cell Biology Platforms, Inserm, CNRS, Paris Saclay Saclay, Institute Gustave Roussy, Villejuif, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I2801843802"]},{"raw_affiliation_string":"Team \"Metabolism, Cancer & Immunity\", Cordeliers Research Center, Inserm, Paris Cit\u00e9 University, Sorbonne University, Paris, 75006, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5075296559","https://openalex.org/A5077808010"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I2801843802","https://openalex.org/I39804081","https://openalex.org/I4210092322","https://openalex.org/I4210097159","https://openalex.org/I4210102325"],"apc_list":{"value":2320,"currency":"USD","value_usd":2320},"apc_paid":{"value":2320,"currency":"USD","value_usd":2320},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.65815959,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"Volume 15","issue":"604318","first_page":"1","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9146000146865845,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9146000146865845,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.037700001150369644,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.01209999993443489,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acyl-coa-binding-protein","display_name":"acyl-CoA binding protein","score":0.8259999752044678},{"id":"https://openalex.org/keywords/diazepam-binding-inhibitor","display_name":"diazepam binding inhibitor","score":0.8939999938011169},{"id":"https://openalex.org/keywords/lamin-a","display_name":"lamin A","score":0.703000009059906},{"id":"https://openalex.org/keywords/lamin-a-c","display_name":"lamin A/C","score":0.9079999923706055},{"id":"https://openalex.org/keywords/tumor-infiltrating-t-cells","display_name":"tumor-infiltrating T cells","score":0.8999999761581421},{"id":"https://openalex.org/keywords/chemoimmunotherapy","display_name":"chemoimmunotherapy","score":0.8460000157356262},{"id":"https://openalex.org/keywords/oxaliplatin","display_name":"oxaliplatin","score":0.8740000128746033},{"id":"https://openalex.org/keywords/anti-pd-1-therapy","display_name":"anti-PD-1 therapy","score":0.9210000038146973},{"id":"https://openalex.org/keywords/fibrosarcoma","display_name":"fibrosarcoma","score":0.7689999938011169},{"id":"https://openalex.org/keywords/antitumor-immunity","display_name":"antitumor immunity","score":0.7670000195503235},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.875},{"id":"https://openalex.org/keywords/hutchinson-gilford-progeria-syndrome","display_name":"Hutchinson-Gilford progeria syndrome","score":0.6079999804496765},{"id":"https://openalex.org/keywords/endozepines","display_name":"endozepines","score":0.7239999771118164},{"id":"https://openalex.org/keywords/t-cell-activation","display_name":"T cell activation","score":0.6480000019073486}],"concepts":[{"id":"https://openalex.org/C2780654407","wikidata":"https://www.wikidata.org/wiki/Q4253573","display_name":"LMNA","level":4,"score":0.8220000267028809},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5751000046730042},{"id":"https://openalex.org/C2778465436","wikidata":"https://www.wikidata.org/wiki/Q213098","display_name":"Progeria","level":3,"score":0.573199987411499},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5491999983787537},{"id":"https://openalex.org/C179093185","wikidata":"https://www.wikidata.org/wiki/Q424506","display_name":"Lamin","level":3,"score":0.5181999802589417},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.49470001459121704},{"id":"https://openalex.org/C2776495794","wikidata":"https://www.wikidata.org/wiki/Q1362453","display_name":"Fibrosarcoma","level":2,"score":0.4814999997615814},{"id":"https://openalex.org/C2780790343","wikidata":"https://www.wikidata.org/wiki/Q5090610","display_name":"Chemoimmunotherapy","level":4,"score":0.47519999742507935},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4187000095844269},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36469998955726624},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.34060001373291016},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.336899995803833},{"id":"https://openalex.org/C14086860","wikidata":"https://www.wikidata.org/wiki/Q337120","display_name":"Neutralization","level":3,"score":0.33239999413490295},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.31859999895095825},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3165000081062317},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.3127000033855438},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.29429998993873596},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.27410000562667847},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.2669999897480011},{"id":"https://openalex.org/C54009773","wikidata":"https://www.wikidata.org/wiki/Q1429031","display_name":"Transfection","level":3,"score":0.26100000739097595},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.2558000087738037}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.2147/itt.s604318","doi":"https://doi.org/10.2147/itt.s604318","is_oa":true,"landing_page_url":"https://doi.org/10.2147/itt.s604318","pdf_url":null,"source":{"id":"https://openalex.org/S4210174637","display_name":"ImmunoTargets and Therapy","issn_l":"2253-1556","issn":["2253-1556"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ImmunoTargets and Therapy","raw_type":"journal-article"},{"id":"pmid:42774966","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42774966","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ImmunoTargets and therapy","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13596399","doi":null,"is_oa":true,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42774966/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunotargets Ther","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:04e95793156e435d9b232855c927b49f","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/04e95793156e435d9b232855c927b49f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"ImmunoTargets and Therapy, Vol Volume 15, Iss Issue 1, Pp 1-9 (2026)","raw_type":"article"},{"id":"pmh:oai:dovepress.com/119833","doi":null,"is_oa":true,"landing_page_url":"https://www.dovepress.com/acbpdbi-neutralization-stimulates-anticancer-immune-responses-by-upreg-peer-reviewed-fulltext-article-ITT","pdf_url":"https://www.dovepress.com/article/download/119833","source":{"id":"https://openalex.org/S4306401012","display_name":"Dove Medical Press (Taylor and Francis Group)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:HAL:hal-05801081v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-05801081","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ImmunoTargets and Therapy, 2026, Volume15 (604318), pp.1 - 9. ⟨10.2147/itt.s604318⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.2147/itt.s604318","doi":"https://doi.org/10.2147/itt.s604318","is_oa":true,"landing_page_url":"https://doi.org/10.2147/itt.s604318","pdf_url":null,"source":{"id":"https://openalex.org/S4210174637","display_name":"ImmunoTargets and Therapy","issn_l":"2253-1556","issn":["2253-1556"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ImmunoTargets and Therapy","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9907000064849854}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1190173965","display_name":null,"funder_award_id":"France2030","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G1348591106","display_name":null,"funder_award_id":"ANR-23-CE44-0030","funder_id":"https://openalex.org/F4320316862","funder_display_name":"Equipex"},{"id":"https://openalex.org/G1397743473","display_name":null,"funder_award_id":"101095604","funder_id":"https://openalex.org/F4320315890","funder_display_name":"Seerave Foundation"},{"id":"https://openalex.org/G1540355574","display_name":null,"funder_award_id":"ANR-22-CE14-0066","funder_id":"https://openalex.org/F4320316862","funder_display_name":"Equipex"},{"id":"https://openalex.org/G1743485262","display_name":null,"funder_award_id":"Cancer_18006","funder_id":"https://openalex.org/F4320323807","funder_display_name":"Institut National Du Cancer"},{"id":"https://openalex.org/G1912211089","display_name":null,"funder_award_id":"RHUS-0017","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G1941370527","display_name":null,"funder_award_id":"ANR-23-R4HC-0006 Ener-LIGHT","funder_id":"https://openalex.org/F4320316862","funder_display_name":"Equipex"},{"id":"https://openalex.org/G2109069054","display_name":null,"funder_award_id":"21-ESRE-0028","funder_id":"https://openalex.org/F4320323807","funder_display_name":"Institut National Du Cancer"},{"id":"https://openalex.org/G2179318311","display_name":null,"funder_award_id":"ANR-23-R4HC-0006 En-er-LIGHT","funder_id":"https://openalex.org/F4320315890","funder_display_name":"Seerave Foundation"},{"id":"https://openalex.org/G2260018823","display_name":"Lung cancer prevention and interception","funder_award_id":"ANR-23-RHUS-0010","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G2264961340","display_name":"Biomarkers affecting the transition from cardiovascular disease to lung cancer: towards stratified interception.","funder_award_id":"101095604","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G2351262490","display_name":null,"funder_award_id":"101052444","funder_id":"https://openalex.org/F4320315890","funder_display_name":"Seerave Foundation"},{"id":"https://openalex.org/G2469459663","display_name":null,"funder_award_id":"ANR-21-RHUS-0017","funder_id":"https://openalex.org/F4320320893","funder_display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale"},{"id":"https://openalex.org/G2485135851","display_name":null,"funder_award_id":"825410","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G2633149742","display_name":"Gut OncoMicrobiome Signatures (GOMS) associated with cancer incidence, prognosis and prediction of treatment response.","funder_award_id":"825410","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G2699422577","display_name":null,"funder_award_id":"101095604","funder_id":"https://openalex.org/F4320323807","funder_display_name":"Institut National Du Cancer"},{"id":"https://openalex.org/G2714391379","display_name":null,"funder_award_id":"ANR-21-RHUS-0017","funder_id":"https://openalex.org/F4320315890","funder_display_name":"Seerave Foundation"},{"id":"https://openalex.org/G3116448791","display_name":null,"funder_award_id":"101095604","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G3231222199","display_name":null,"funder_award_id":"#ANR-18-IDEX-0001","funder_id":"https://openalex.org/F4320323807","funder_display_name":"Institut National Du Cancer"},{"id":"https://openalex.org/G3280152251","display_name":"Mitochondrial copper targeting to modulate inflammatory macrophages","funder_award_id":"ANR-23-CE44-0030","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G3489513111","display_name":null,"funder_award_id":"ANR-23-RHUS-0010","funder_id":"https://openalex.org/F4320320893","funder_display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale"},{"id":"https://openalex.org/G3745988485","display_name":null,"funder_award_id":"ANR-23-R4HC-0006 Ener-LIGHT","funder_id":"https://openalex.org/F4320320893","funder_display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale"},{"id":"https://openalex.org/G4364925233","display_name":null,"funder_award_id":"ERC-2021-ADG","funder_id":"https://openalex.org/F4320323807","funder_display_name":"Institut National Du Cancer"},{"id":"https://openalex.org/G4656594441","display_name":null,"funder_award_id":"ANR18","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G4744413284","display_name":null,"funder_award_id":"ANR-23-R4HC-0006 En-er-LIGHT","funder_id":"https://openalex.org/F4320323807","funder_display_name":"Institut National Du Cancer"},{"id":"https://openalex.org/G4880911435","display_name":null,"funder_award_id":"825410","funder_id":"https://openalex.org/F4320320893","funder_display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale"},{"id":"https://openalex.org/G4900465205","display_name":null,"funder_award_id":"825410","funder_id":"https://openalex.org/F4320323807","funder_display_name":"Institut National Du Cancer"},{"id":"https://openalex.org/G4968846622","display_name":null,"funder_award_id":"ERC-2021-ADG","funder_id":"https://openalex.org/F4320320893","funder_display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale"},{"id":"https://openalex.org/G5409723808","display_name":"Microbiota-centered interventions to solve antibiotics-induced primary resistance to immune checkpoint inhibitors","funder_award_id":"ANR-21-RHUS-0017","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G571454778","display_name":"Energizing the failing heart","funder_award_id":"ANR-23-R4HC-0006","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G5767140378","display_name":null,"funder_award_id":"ANR-18-IDEX-0001","funder_id":"https://openalex.org/F4320315890","funder_display_name":"Seerave Foundation"},{"id":"https://openalex.org/G5790172013","display_name":null,"funder_award_id":"ERC-2021-ADG","funder_id":"https://openalex.org/F4320315890","funder_display_name":"Seerave Foundation"},{"id":"https://openalex.org/G5851709705","display_name":null,"funder_award_id":"ERC-2021-ADG","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G5953624409","display_name":null,"funder_award_id":"21-ESRE-0028","funder_id":"https://openalex.org/F4320315890","funder_display_name":"Seerave Foundation"},{"id":"https://openalex.org/G6300988664","display_name":null,"funder_award_id":"101052444","funder_id":"https://openalex.org/F4320320893","funder_display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale"},{"id":"https://openalex.org/G6610179393","display_name":null,"funder_award_id":"101095604","funder_id":"https://openalex.org/F4320320893","funder_display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale"},{"id":"https://openalex.org/G6718544961","display_name":null,"funder_award_id":"ANR-23-RHUS-0010","funder_id":"https://openalex.org/F4320315890","funder_display_name":"Seerave Foundation"},{"id":"https://openalex.org/G7080048889","display_name":null,"funder_award_id":"ANR-23","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G7309355080","display_name":null,"funder_award_id":"ANR-23-RHUS-0010","funder_id":"https://openalex.org/F4320323807","funder_display_name":"Institut National Du Cancer"},{"id":"https://openalex.org/G7319818416","display_name":null,"funder_award_id":"101052444","funder_id":"https://openalex.org/F4320323807","funder_display_name":"Institut National Du Cancer"},{"id":"https://openalex.org/G7662726268","display_name":null,"funder_award_id":"825410","funder_id":"https://openalex.org/F4320315890","funder_display_name":"Seerave Foundation"},{"id":"https://openalex.org/G8074704899","display_name":null,"funder_award_id":"CA23119","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G82931992","display_name":null,"funder_award_id":"ERC-2021-ADG","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G8316913482","display_name":null,"funder_award_id":"21-ESRE-0028","funder_id":"https://openalex.org/F4320320893","funder_display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale"},{"id":"https://openalex.org/G8471630636","display_name":null,"funder_award_id":"ANR-18-IDEX-0001","funder_id":"https://openalex.org/F4320320893","funder_display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale"},{"id":"https://openalex.org/G8538166538","display_name":"Universit\u00e9 de Paris","funder_award_id":"ANR-18-IDEX-0001","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G8815602807","display_name":"The RUSH (retention using selective hooks) system: a chemical-genetic system for the in vivo manipulation of intercellular communication","funder_award_id":"ANR-22-CE14-0066","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G8991455713","display_name":null,"funder_award_id":"ANR-21-RHUS-0017","funder_id":"https://openalex.org/F4320323807","funder_display_name":"Institut National Du Cancer"}],"funders":[{"id":"https://openalex.org/F4320315890","display_name":"Seerave Foundation","ror":"https://ror.org/01p3x3413"},{"id":"https://openalex.org/F4320316862","display_name":"Equipex","ror":null},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"},{"id":"https://openalex.org/F4320320893","display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","ror":"https://ror.org/02vjkv261"},{"id":"https://openalex.org/F4320323807","display_name":"Institut National Du Cancer","ror":"https://ror.org/03m8vkq32"},{"id":"https://openalex.org/F4320325668","display_name":"Direction G\u00e9n\u00e9rale de l\u2019offre de Soins","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7213534369.pdf","grobid_xml":"https://content.openalex.org/works/W7213534369.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W1487741670","https://openalex.org/W1992900610","https://openalex.org/W2006846732","https://openalex.org/W2021302591","https://openalex.org/W2025462328","https://openalex.org/W2046452940","https://openalex.org/W2059094579","https://openalex.org/W2062502129","https://openalex.org/W2070948814","https://openalex.org/W2072569072","https://openalex.org/W2073111593","https://openalex.org/W2128635719","https://openalex.org/W2146852283","https://openalex.org/W2149404667","https://openalex.org/W2150467984","https://openalex.org/W2153684163","https://openalex.org/W2328465112","https://openalex.org/W2469136165","https://openalex.org/W2784251360","https://openalex.org/W2894816987","https://openalex.org/W2942701849","https://openalex.org/W2953476200","https://openalex.org/W2965555626","https://openalex.org/W2968756620","https://openalex.org/W3167596982","https://openalex.org/W3174909341","https://openalex.org/W3176365456","https://openalex.org/W3202160634","https://openalex.org/W4285085650","https://openalex.org/W4300594572","https://openalex.org/W4382010582","https://openalex.org/W4386151463","https://openalex.org/W4386826948","https://openalex.org/W4387344358","https://openalex.org/W4391116295","https://openalex.org/W4394812354","https://openalex.org/W4396879504","https://openalex.org/W4402321108","https://openalex.org/W4402497534","https://openalex.org/W4403505834","https://openalex.org/W4406931388","https://openalex.org/W4407955903","https://openalex.org/W4408389018","https://openalex.org/W4410553528","https://openalex.org/W4412073672","https://openalex.org/W4412086774","https://openalex.org/W7133565991","https://openalex.org/W7148415119"],"related_works":["https://openalex.org/W7133565991","https://openalex.org/W3082849621","https://openalex.org/W3043056039","https://openalex.org/W2482008588","https://openalex.org/W3189171857","https://openalex.org/W7140341081","https://openalex.org/W4407776688","https://openalex.org/W3088715298","https://openalex.org/W4386878257","https://openalex.org/W4385685682"],"abstract_inverted_index":{"Introduction:":[0],"Acyl":[1],"CoA":[2],"binding":[3,11],"protein":[4],"(ACBP,":[5],"encoded":[6],"by":[7,175],"the":[8,37,45,48,66,71,106,153,181,185,209],"gene":[9,50],"diazepam":[10],"inhibitor":[12],",":[13],"DBI)":[14],"is":[15,178,205],"a":[16,89,113,197],"tissue":[17],"stress":[18],"hormone":[19],"involved":[20,207],"in":[21,36,56,70,84,105,129,138,145,161,208],"pathological":[22],"aging":[23],"that":[24,172,194],"mediates":[25],"immunosuppression.":[26],"The":[27],"antibody-mediated":[28],"neutralization":[29,132],"of":[30,39,47,68,74,108,184,187,212],"ACBP/DBI":[31,41,75,131,144,190,213],"enhances":[32],"anticancer":[33,72,182],"immune":[34,220],"responses":[35],"context":[38,107],"chemoimmunotherapy.":[40],"inhibition":[42],"also":[43],"upregulates":[44],"expression":[46,83,174],"anti-aging":[49],"Lmna":[51,69,82,173],"coding":[52],"for":[53,180,200],"Lamin":[54],"A":[55],"tumor-infiltrating":[57],"T":[58,85,146,176,202],"lymphocytes.":[59],"This":[60,156],"study":[61],"was":[62,120,135,158],"designed":[63],"to":[64,88,125,150,152],"explore":[65],"role":[67],"effects":[73,183,211],"neutralization.":[76,191,214],"Methods:":[77],"We":[78,192],"generated":[79],"mice":[80,142],"lacking":[81,143],"lymphocytes":[86,177],"due":[87],"conditional":[90],"knockout.":[91],"Mice":[92],"bearing":[93],"orthotopic":[94],"(cutaneous)":[95],"MCA205":[96,140],"fibrosarcomas":[97],"were":[98],"treated":[99],"with":[100,112],"an":[101],"anti-ACBP/DBI":[102],"monoclonal":[103],"antibody":[104],"chemoimmuntherapy":[109],"(oxaliplatin":[110],"combined":[111],"PD-1":[114],"blocking":[115],"antibody),":[116],"and":[117,164,189],"tumor":[118],"growth":[119],"monitored.":[121],"Results:":[122],"As":[123],"compared":[124],"immunocompetent":[126],"control":[127],"mice,":[128],"which":[130],"plus":[133],"chemoimmunotherapy":[134,188],"highly":[136],"efficient":[137],"reducing":[139],"growth,":[141],"cells":[147],"largely":[148],"failed":[149],"respond":[151],"therapeutic":[154],"intervention.":[155],"result":[157],"undistinguishably":[159],"observed":[160],"both":[162],"female":[163],"male":[165],"mice.":[166],"Discussion:":[167],"Altogether,":[168],"these":[169],"results":[170],"indicate":[171],"required":[179,199],"combination":[186],"conclude":[193],"lamin":[195],"A,":[196],"factor":[198],"optimal":[201],"cell":[203],"activation,":[204],"causally":[206],"immunostimulatory":[210],"Keywords:":[215],"endozepine,":[216],"Hutchinson-Gilford":[217],"progeroid":[218],"syndrome,":[219],"checkpoint":[221],"inhibitor,":[222],"immunotherapy,":[223],"progeria":[224]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2026-09-18T00:00:00"}