{"id":"https://openalex.org/W7213435938","doi":"https://doi.org/10.1016/j.jaccas.2026.109329","title":"Radiation Dose Optimization in Coronary CT Angiography","display_name":"Radiation Dose Optimization in Coronary CT Angiography","publication_year":2026,"publication_date":"2026-09-01","ids":{"openalex":"https://openalex.org/W7213435938","doi":"https://doi.org/10.1016/j.jaccas.2026.109329","pmid":"https://pubmed.ncbi.nlm.nih.gov/42752009","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13728305"},"language":"en","primary_location":{"id":"doi:10.1016/j.jaccas.2026.109329","doi":"https://doi.org/10.1016/j.jaccas.2026.109329","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaccas.2026.109329","pdf_url":null,"source":{"id":"https://openalex.org/S4210180918","display_name":"JACC Case Reports","issn_l":"2666-0849","issn":["2666-0849"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JACC: Case Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.jaccas.2026.109329","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055138081","display_name":"Muhammad Kashif","orcid":"https://orcid.org/0000-0003-1274-6742","observed_orcids":["https://orcid.org/0000-0003-1274-6742","https://orcid.org/0009-0006-1561-0911"]},"institutions":[{"id":"https://openalex.org/I4210115183","display_name":"Tabba Heart Institute","ror":"https://ror.org/027ade760","country_code":"PK","type":"healthcare","lineage":["https://openalex.org/I4210115183"]}],"countries":["PK"],"is_corresponding":true,"raw_author_name":"Muhammad Kashif","raw_affiliation_strings":["Department of Clinical Research Cardiology, Tabba Heart Institute, Karachi, Pakistan. Electronic address: muhammad.kashif@tabbaheart.org"],"raw_orcid":"https://orcid.org/0009-0006-1561-0911","affiliations":[{"raw_affiliation_string":"Department of Clinical Research Cardiology, Tabba Heart Institute, Karachi, Pakistan. Electronic address: muhammad.kashif@tabbaheart.org","institution_ids":["https://openalex.org/I4210115183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5151914789","display_name":"Danish Waris Ali","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115183","display_name":"Tabba Heart Institute","ror":"https://ror.org/027ade760","country_code":"PK","type":"healthcare","lineage":["https://openalex.org/I4210115183"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Danish Waris Ali","raw_affiliation_strings":["Department of Cardiology, Tabba Heart Institute, Karachi, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Tabba Heart Institute, Karachi, Pakistan","institution_ids":["https://openalex.org/I4210115183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045035070","display_name":"Adeel Ur Rahman Siddiqui","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115183","display_name":"Tabba Heart Institute","ror":"https://ror.org/027ade760","country_code":"PK","type":"healthcare","lineage":["https://openalex.org/I4210115183"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Adeel Ur Rahman Siddiqui","raw_affiliation_strings":["Department of Cardiology, Tabba Heart Institute, Karachi, Pakistan; Consultant Cardiologist and Director Radiology Tabba Heart Institute, Karachi, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Tabba Heart Institute, Karachi, Pakistan; Consultant Cardiologist and Director Radiology Tabba Heart Institute, Karachi, Pakistan","institution_ids":["https://openalex.org/I4210115183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5151902890","display_name":"Muhammad Ali","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115183","display_name":"Tabba Heart Institute","ror":"https://ror.org/027ade760","country_code":"PK","type":"healthcare","lineage":["https://openalex.org/I4210115183"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Muhammad Ali","raw_affiliation_strings":["Department of Cardiology, Tabba Heart Institute, Karachi, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Tabba Heart Institute, Karachi, Pakistan","institution_ids":["https://openalex.org/I4210115183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047014849","display_name":"Sumair Ahmed","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115183","display_name":"Tabba Heart Institute","ror":"https://ror.org/027ade760","country_code":"PK","type":"healthcare","lineage":["https://openalex.org/I4210115183"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Sumair Ahmed","raw_affiliation_strings":["Department of Cardiology, Tabba Heart Institute, Karachi, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Tabba Heart Institute, Karachi, Pakistan","institution_ids":["https://openalex.org/I4210115183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5158695196","display_name":"Muhammad Arshad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115183","display_name":"Tabba Heart Institute","ror":"https://ror.org/027ade760","country_code":"PK","type":"healthcare","lineage":["https://openalex.org/I4210115183"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Muhammad Arshad","raw_affiliation_strings":["Department of Clinical Research Cardiology, Tabba Heart Institute, Karachi, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Research Cardiology, Tabba Heart Institute, Karachi, Pakistan","institution_ids":["https://openalex.org/I4210115183"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063762383","display_name":"Bashir Hanif","orcid":"https://orcid.org/0000-0003-4354-4692","observed_orcids":["https://orcid.org/0000-0003-4354-4692"]},"institutions":[{"id":"https://openalex.org/I4210115183","display_name":"Tabba Heart Institute","ror":"https://ror.org/027ade760","country_code":"PK","type":"healthcare","lineage":["https://openalex.org/I4210115183"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Bashir Hanif","raw_affiliation_strings":["Department of Clinical Research Cardiology, Tabba Heart Institute, Karachi, Pakistan; Department of Cardiology, Tabba Heart Institute, Karachi, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Research Cardiology, Tabba Heart Institute, Karachi, Pakistan; Department of Cardiology, Tabba Heart Institute, Karachi, Pakistan","institution_ids":["https://openalex.org/I4210115183"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5055138081"],"corresponding_institution_ids":["https://openalex.org/I4210115183"],"apc_list":{"value":850,"currency":"USD","value_usd":850},"apc_paid":{"value":850,"currency":"USD","value_usd":850},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.63363402,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"31","issue":"37","first_page":"109329","last_page":"109329"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10844","display_name":"Radiation Dose and Imaging","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10844","display_name":"Radiation Dose and Imaging","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.006500000134110451,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/coronary-ct-angiography","display_name":"coronary CT angiography","score":0.9789999723434448},{"id":"https://openalex.org/keywords/radiation-dose-reduction","display_name":"radiation dose reduction","score":0.8870000243186951},{"id":"https://openalex.org/keywords/effective-dose","display_name":"effective dose","score":0.871999979019165},{"id":"https://openalex.org/keywords/dose-length-product","display_name":"dose-length product","score":0.9879999756813049},{"id":"https://openalex.org/keywords/image-quality","display_name":"image quality","score":0.875},{"id":"https://openalex.org/keywords/resource-limited-settings","display_name":"resource-limited settings","score":0.7599999904632568},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.6740000247955322}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6966000199317932},{"id":"https://openalex.org/C2987700449","wikidata":"https://www.wikidata.org/wiki/Q186161","display_name":"Radiation dose","level":2,"score":0.6402000188827515},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.5547000169754028},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4562000036239624},{"id":"https://openalex.org/C2780643987","wikidata":"https://www.wikidata.org/wiki/Q468414","display_name":"Angiography","level":2,"score":0.42309999465942383},{"id":"https://openalex.org/C3019004856","wikidata":"https://www.wikidata.org/wiki/Q42297149","display_name":"Coronary angiography","level":3,"score":0.33379998803138733},{"id":"https://openalex.org/C544519230","wikidata":"https://www.wikidata.org/wiki/Q32566","display_name":"Computed tomography","level":2,"score":0.3156000077724457},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.3140000104904175},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.2856000065803528},{"id":"https://openalex.org/C149857219","wikidata":"https://www.wikidata.org/wiki/Q5239054","display_name":"Effective dose (radiation)","level":2,"score":0.260699987411499},{"id":"https://openalex.org/C2779925993","wikidata":"https://www.wikidata.org/wiki/Q336938","display_name":"Radiation exposure","level":2,"score":0.25940001010894775},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.25029999017715454}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1016/j.jaccas.2026.109329","doi":"https://doi.org/10.1016/j.jaccas.2026.109329","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaccas.2026.109329","pdf_url":null,"source":{"id":"https://openalex.org/S4210180918","display_name":"JACC Case Reports","issn_l":"2666-0849","issn":["2666-0849"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JACC: Case Reports","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13728305","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13728305/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13728305/pdf/main.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JACC Case Rep","raw_type":"Text"},{"id":"pmid:42752009","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42752009","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JACC. Case reports","raw_type":"Case Reports"},{"id":"pmh:oai:doaj.org/article:236566e8e85043a8b24845211de8027c","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/236566e8e85043a8b24845211de8027c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"JACC: Case Reports, Vol 31, Iss 37, Pp 109329- (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.jaccas.2026.109329","doi":"https://doi.org/10.1016/j.jaccas.2026.109329","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaccas.2026.109329","pdf_url":null,"source":{"id":"https://openalex.org/S4210180918","display_name":"JACC Case Reports","issn_l":"2666-0849","issn":["2666-0849"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JACC: Case Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9922999739646912}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7213435938.pdf","grobid_xml":"https://content.openalex.org/works/W7213435938.grobid-xml"},"referenced_works_count":7,"referenced_works":["https://openalex.org/W1490630562","https://openalex.org/W3170353447","https://openalex.org/W3213353811","https://openalex.org/W4412522317","https://openalex.org/W4413414100","https://openalex.org/W4416364956","https://openalex.org/W7128535160"],"related_works":["https://openalex.org/W2085564160","https://openalex.org/W2949497777","https://openalex.org/W4415023118","https://openalex.org/W323404842","https://openalex.org/W4415023284","https://openalex.org/W4412494678","https://openalex.org/W2985775668","https://openalex.org/W2946124359","https://openalex.org/W2324630339","https://openalex.org/W4376645324"],"abstract_inverted_index":{"BACKGROUND:":[0],"Coronary":[1],"computed":[2],"tomography":[3],"angiography":[4],"(CCTA)":[5],"is":[6],"increasingly":[7],"used":[8],"for":[9,158],"the":[10],"evaluation":[11],"of":[12,51,78],"coronary":[13],"artery":[14],"disease;":[15],"however,":[16],"radiation":[17,26,47,93,145],"exposure":[18,48,146],"remains":[19],"a":[20,155],"patient":[21],"safety":[22],"concern.":[23],"Data":[24],"on":[25],"dose":[27,94],"optimization":[28,140],"from":[29,98],"low-":[30],"and":[31,54,87,113,151],"middle-income":[32],"countries":[33],"are":[34],"limited.":[35],"PROJECT":[36,64],"RATIONALE:":[37],"Tabba":[38],"Heart":[39],"Institute":[40],"Karachi":[41],"identified":[42],"opportunities":[43],"to":[44,101],"reduce":[45,143],"CCTA":[46,80,107,144],"through":[49],"implementation":[50],"heart":[52],"rate":[53],"body":[55],"mass":[56],"index-guided":[57],"acquisition":[58],"protocols":[59],"while":[60],"maintaining":[61],"image":[62,129,149],"quality.":[63],"SUMMARY:":[65],"A":[66,76],"quality":[67,130,150],"improvement":[68],"initiative":[69],"was":[70],"implemented":[71],"using":[72],"patient-specific":[73],"scanning":[74],"protocols.":[75],"total":[77,114],"422":[79],"examinations":[81],"were":[82,126],"evaluated,":[83],"including":[84],"117":[85],"preintervention":[86],"305":[88],"postintervention":[89],"studies.":[90],"Median":[91],"effective":[92],"decreased":[95,110],"by":[96,111,117],"45.5%,":[97],"8.8":[99],"mSv":[100,103],"4.8":[102],"(P":[104],"<":[105,121],"0.001).":[106,122],"dose-length":[108,115],"product":[109,116],"46.5%":[112],"39.8%":[118],"(both":[119],"P":[120],"No":[123],"significant":[124],"differences":[125],"observed":[127],"in":[128,162],"metrics":[131],"or":[132],"repeat":[133],"scan":[134],"rates.":[135],"TAKE-HOME":[136],"MESSAGE:":[137],"Technologist-driven":[138],"protocol":[139],"can":[141],"substantially":[142],"without":[147],"compromising":[148],"may":[152],"serve":[153],"as":[154],"scalable":[156],"model":[157],"cardiovascular":[159],"imaging":[160],"programs":[161],"resource-constrained":[163],"settings.":[164]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2026-09-17T00:00:00"}