{"id":"https://openalex.org/W7213324796","doi":"https://doi.org/10.64898/2026.09.14.26363009","title":"Epidemiology of Shigella sonnei and Shigella flexneri in the Global Pediatric Diarrhea Surveillance network, 2017\u20132022","display_name":"Epidemiology of Shigella sonnei and Shigella flexneri in the Global Pediatric Diarrhea Surveillance network, 2017\u20132022","publication_year":2026,"publication_date":"2026-09-15","ids":{"openalex":"https://openalex.org/W7213324796","doi":"https://doi.org/10.64898/2026.09.14.26363009"},"language":"en","primary_location":{"id":"doi:10.64898/2026.09.14.26363009","doi":"https://doi.org/10.64898/2026.09.14.26363009","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.14.26363009","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/15/2026.09.14.26363009.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/15/2026.09.14.26363009.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5122261159","display_name":"Jie Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I108688024","display_name":"Qingdao University","ror":"https://ror.org/021cj6z65","country_code":"CN","type":"education","lineage":["https://openalex.org/I108688024"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Liu","raw_affiliation_strings":["School of Public Health, Qingdao University, Qingdao, Shandong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Public Health, Qingdao University, Qingdao, Shandong, China","institution_ids":["https://openalex.org/I108688024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5095091483","display_name":"Myra Lewontin","orcid":"https://orcid.org/0000-0002-9239-7783","observed_orcids":["https://orcid.org/0000-0002-9239-7783"]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Myra Lewontin","raw_affiliation_strings":["University of Virginia School of Medicine, Charlottesville, VA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Virginia School of Medicine, Charlottesville, VA, USA","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018313758","display_name":"Sarah Elwood","orcid":"https://orcid.org/0000-0003-0904-3552","observed_orcids":["https://orcid.org/0000-0003-0904-3552"]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah E. Elwood","raw_affiliation_strings":["Division of Infectious Diseases & International Health, University of Virginia, Charlottesville, VA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases & International Health, University of Virginia, Charlottesville, VA, USA","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109926414","display_name":"Shilpa S. Iyer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210105654","display_name":"World Health Organization","ror":"https://ror.org/01f80g185","country_code":"CH","type":"government","lineage":["https://openalex.org/I4210105654"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Shilpa S. Iyer","raw_affiliation_strings":["World Health Organization, Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"World Health Organization, Geneva, Switzerland","institution_ids":["https://openalex.org/I4210105654"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086836504","display_name":"S\u00e9bastien Antoni","orcid":"https://orcid.org/0000-0002-0911-0711","observed_orcids":["https://orcid.org/0000-0002-0911-0711"]},"institutions":[{"id":"https://openalex.org/I4210105654","display_name":"World Health Organization","ror":"https://ror.org/01f80g185","country_code":"CH","type":"government","lineage":["https://openalex.org/I4210105654"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"S\u00e9bastien Antoni","raw_affiliation_strings":["World Health Organization, Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"World Health Organization, Geneva, Switzerland","institution_ids":["https://openalex.org/I4210105654"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036335134","display_name":"Gloria Janneth Rey-Benito","orcid":"https://orcid.org/0009-0004-5368-1740","observed_orcids":["https://orcid.org/0009-0004-5368-1740"]},"institutions":[{"id":"https://openalex.org/I4210089393","display_name":"World Health Organization Regional Office for the Americas","ror":"https://ror.org/008kev776","country_code":"US","type":"government","lineage":["https://openalex.org/I4210089393","https://openalex.org/I4210105654"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gloria Rey-Benito","raw_affiliation_strings":["Pan American Health Organization, World Health Organization Regional Office for the Americas, Washington, DC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pan American Health Organization, World Health Organization Regional Office for the Americas, Washington, DC, USA","institution_ids":["https://openalex.org/I4210089393"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5137151167","display_name":"Claudia Ortiz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210089393","display_name":"World Health Organization Regional Office for the Americas","ror":"https://ror.org/008kev776","country_code":"US","type":"government","lineage":["https://openalex.org/I4210089393","https://openalex.org/I4210105654"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Claudia Ortiz","raw_affiliation_strings":["Pan American Health Organization, World Health Organization Regional Office for the Americas, Washington, DC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pan American Health Organization, World Health Organization Regional Office for the Americas, Washington, DC, USA","institution_ids":["https://openalex.org/I4210089393"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044574844","display_name":"Goitom Gebremedhin Weldegebriel","orcid":"https://orcid.org/0000-0002-0535-3484","observed_orcids":["https://orcid.org/0000-0002-0535-3484"]},"institutions":[{"id":"https://openalex.org/I4210139943","display_name":"World Health Organization Regional Office for Africa","ror":"https://ror.org/04rtx9382","country_code":"CG","type":"government","lineage":["https://openalex.org/I4210105654","https://openalex.org/I4210139943"]}],"countries":["CG"],"is_corresponding":false,"raw_author_name":"Goitom Weldegebriel","raw_affiliation_strings":["World Health Organization Regional Office for Africa, Brazzaville, Congo"],"raw_orcid":"https://orcid.org/0000-0002-0535-3484","affiliations":[{"raw_affiliation_string":"World Health Organization Regional Office for Africa, Brazzaville, Congo","institution_ids":["https://openalex.org/I4210139943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110958058","display_name":"Joseph Biey","orcid":"https://orcid.org/0000-0003-2136-0251","observed_orcids":["https://orcid.org/0000-0003-2136-0251"]},"institutions":[{"id":"https://openalex.org/I4210139943","display_name":"World Health Organization Regional Office for Africa","ror":"https://ror.org/04rtx9382","country_code":"CG","type":"government","lineage":["https://openalex.org/I4210105654","https://openalex.org/I4210139943"]}],"countries":["CG"],"is_corresponding":false,"raw_author_name":"Joseph Biey","raw_affiliation_strings":["World Health Organization Regional Office for Africa, Brazzaville, Congo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"World Health Organization Regional Office for Africa, Brazzaville, Congo","institution_ids":["https://openalex.org/I4210139943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112480620","display_name":"Jason Mathiu Mwenda","orcid":"https://orcid.org/0000-0001-5880-2637","observed_orcids":["https://orcid.org/0000-0001-5880-2637"]},"institutions":[{"id":"https://openalex.org/I4210139943","display_name":"World Health Organization Regional Office for Africa","ror":"https://ror.org/04rtx9382","country_code":"CG","type":"government","lineage":["https://openalex.org/I4210105654","https://openalex.org/I4210139943"]}],"countries":["CG"],"is_corresponding":false,"raw_author_name":"Jason M. Mwenda","raw_affiliation_strings":["World Health Organization Regional Office for Africa, Brazzaville, Congo"],"raw_orcid":"https://orcid.org/0000-0001-5880-2637","affiliations":[{"raw_affiliation_string":"World Health Organization Regional Office for Africa, Brazzaville, Congo","institution_ids":["https://openalex.org/I4210139943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025610688","display_name":"Roberta Pastore","orcid":"https://orcid.org/0000-0002-4110-774X","observed_orcids":["https://orcid.org/0000-0002-4110-774X"]},"institutions":[{"id":"https://openalex.org/I4210099008","display_name":"World Health Organization Regional Office for Europe","ror":"https://ror.org/01rz37c55","country_code":"DK","type":"government","lineage":["https://openalex.org/I4210099008","https://openalex.org/I4210105654"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Roberta Pastore","raw_affiliation_strings":["World Health Organization Regional Office for Europe, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"World Health Organization Regional Office for Europe, Copenhagen, Denmark","institution_ids":["https://openalex.org/I4210099008"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091794179","display_name":"Dovile Videbaek","orcid":"https://orcid.org/0000-0002-5085-0981","observed_orcids":["https://orcid.org/0000-0002-5085-0981"]},"institutions":[{"id":"https://openalex.org/I4210099008","display_name":"World Health Organization Regional Office for Europe","ror":"https://ror.org/01rz37c55","country_code":"DK","type":"government","lineage":["https://openalex.org/I4210099008","https://openalex.org/I4210105654"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Dovile Videbaek","raw_affiliation_strings":["World Health Organization Regional Office for Europe, Copenhagen, Denmark"],"raw_orcid":"https://orcid.org/0000-0002-5085-0981","affiliations":[{"raw_affiliation_string":"World Health Organization Regional Office for Europe, Copenhagen, Denmark","institution_ids":["https://openalex.org/I4210099008"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5151734736","display_name":"Samarjit Singh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210099008","display_name":"World Health Organization Regional Office for Europe","ror":"https://ror.org/01rz37c55","country_code":"DK","type":"government","lineage":["https://openalex.org/I4210099008","https://openalex.org/I4210105654"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Simarjit Singh","raw_affiliation_strings":["World Health Organization Regional Office for Europe, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"World Health Organization Regional Office for Europe, Copenhagen, Denmark","institution_ids":["https://openalex.org/I4210099008"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053190305","display_name":"Emmanuel Njambe","orcid":"https://orcid.org/0000-0002-3870-7525","observed_orcids":["https://orcid.org/0000-0002-3870-7525"]},"institutions":[{"id":"https://openalex.org/I4210112062","display_name":"World Health Organization Regional Office for South-East Asia","ror":"https://ror.org/02wae9s43","country_code":"IN","type":"government","lineage":["https://openalex.org/I4210105654","https://openalex.org/I4210112062"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Emmanuel Njambe","raw_affiliation_strings":["World Health Organization Regional Office for South-East Asia, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"World Health Organization Regional Office for South-East Asia, New Delhi, India","institution_ids":["https://openalex.org/I4210112062"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035474882","display_name":"Lucky Sangal","orcid":"https://orcid.org/0000-0002-2553-4768","observed_orcids":["https://orcid.org/0000-0002-2553-4768"]},"institutions":[{"id":"https://openalex.org/I4210112062","display_name":"World Health Organization Regional Office for South-East Asia","ror":"https://ror.org/02wae9s43","country_code":"IN","type":"government","lineage":["https://openalex.org/I4210105654","https://openalex.org/I4210112062"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Lucky Sangal","raw_affiliation_strings":["World Health Organization Regional Office for South-East Asia, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"World Health Organization Regional Office for South-East Asia, New Delhi, India","institution_ids":["https://openalex.org/I4210112062"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064496893","display_name":"Deepak Dhongde","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210112062","display_name":"World Health Organization Regional Office for South-East Asia","ror":"https://ror.org/02wae9s43","country_code":"IN","type":"government","lineage":["https://openalex.org/I4210105654","https://openalex.org/I4210112062"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Deepak Dhongde","raw_affiliation_strings":["World Health Organization Regional Office for South-East Asia, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"World Health Organization Regional Office for South-East Asia, New Delhi, India","institution_ids":["https://openalex.org/I4210112062"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037127310","display_name":"Varja Grabovac","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210150475","display_name":"World Health Organization Regional Office for the Western Pacific","ror":"https://ror.org/04nfvby78","country_code":"PH","type":"government","lineage":["https://openalex.org/I4210105654","https://openalex.org/I4210150475"]}],"countries":["PH"],"is_corresponding":false,"raw_author_name":"Varja Grabovac","raw_affiliation_strings":["World Health Organization Regional Office for the Western Pacific, Manila, Philippines"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"World Health Organization Regional Office for the Western Pacific, Manila, Philippines","institution_ids":["https://openalex.org/I4210150475"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060269832","display_name":"Josephine Logronio","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210150475","display_name":"World Health Organization Regional Office for the Western Pacific","ror":"https://ror.org/04nfvby78","country_code":"PH","type":"government","lineage":["https://openalex.org/I4210105654","https://openalex.org/I4210150475"]}],"countries":["PH"],"is_corresponding":false,"raw_author_name":"Josephine Logronio","raw_affiliation_strings":["World Health Organization Regional Office for the Western Pacific, Manila, Philippines"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"World Health Organization Regional Office for the Western Pacific, Manila, Philippines","institution_ids":["https://openalex.org/I4210150475"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112175794","display_name":"Kamal Fahmy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210105726","display_name":"World Health Organization Regional Office for the Eastern Mediterranean","ror":"https://ror.org/01h4ywk72","country_code":"EG","type":"government","lineage":["https://openalex.org/I4210105654","https://openalex.org/I4210105726"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Kamal Fahmy","raw_affiliation_strings":["World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt","institution_ids":["https://openalex.org/I4210105726"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085586259","display_name":"Amany Ghoniem","orcid":"https://orcid.org/0009-0008-5382-5782","observed_orcids":["https://orcid.org/0009-0008-5382-5782"]},"institutions":[{"id":"https://openalex.org/I4210105726","display_name":"World Health Organization Regional Office for the Eastern Mediterranean","ror":"https://ror.org/01h4ywk72","country_code":"EG","type":"government","lineage":["https://openalex.org/I4210105654","https://openalex.org/I4210105726"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Amany Ghoniem","raw_affiliation_strings":["World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt","institution_ids":["https://openalex.org/I4210105726"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111563648","display_name":"George Enyimah Armah","orcid":"https://orcid.org/0000-0001-6078-9953","observed_orcids":["https://orcid.org/0000-0001-6078-9953"]},"institutions":[{"id":"https://openalex.org/I138690464","display_name":"University of Ghana","ror":"https://ror.org/01r22mr83","country_code":"GH","type":"education","lineage":["https://openalex.org/I138690464"]},{"id":"https://openalex.org/I4210091910","display_name":"Noguchi Memorial Institute for Medical Research","ror":"https://ror.org/00f1qr933","country_code":"GH","type":"nonprofit","lineage":["https://openalex.org/I138690464","https://openalex.org/I4210091910"]}],"countries":["GH"],"is_corresponding":false,"raw_author_name":"George Armah","raw_affiliation_strings":["Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Accra, Ghana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Accra, Ghana","institution_ids":["https://openalex.org/I138690464","https://openalex.org/I4210091910"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074734172","display_name":"Francis Ekow Dennis","orcid":"https://orcid.org/0000-0003-2078-6955","observed_orcids":["https://orcid.org/0000-0003-2078-6955"]},"institutions":[{"id":"https://openalex.org/I138690464","display_name":"University of Ghana","ror":"https://ror.org/01r22mr83","country_code":"GH","type":"education","lineage":["https://openalex.org/I138690464"]},{"id":"https://openalex.org/I4210091910","display_name":"Noguchi Memorial Institute for Medical Research","ror":"https://ror.org/00f1qr933","country_code":"GH","type":"nonprofit","lineage":["https://openalex.org/I138690464","https://openalex.org/I4210091910"]}],"countries":["GH"],"is_corresponding":false,"raw_author_name":"Francis E. Dennis","raw_affiliation_strings":["Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Accra, Ghana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Accra, Ghana","institution_ids":["https://openalex.org/I138690464","https://openalex.org/I4210091910"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086953874","display_name":"Mapaseka L. Seheri","orcid":"https://orcid.org/0000-0002-6198-3317","observed_orcids":["https://orcid.org/0000-0002-6198-3317"]},"institutions":[{"id":"https://openalex.org/I2802393258","display_name":"Sefako Makgatho Health Sciences University","ror":"https://ror.org/003hsr719","country_code":"ZA","type":"education","lineage":["https://openalex.org/I2802393258"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Mapaseka L. Seheri","raw_affiliation_strings":["Diarrhoeal Pathogens Research Unit, Department of Virology, Sefako Makgatho Health Sciences University, Pretoria, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diarrhoeal Pathogens Research Unit, Department of Virology, Sefako Makgatho Health Sciences University, Pretoria, South Africa","institution_ids":["https://openalex.org/I2802393258"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080627032","display_name":"Nonkululeko B. Magagula","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802393258","display_name":"Sefako Makgatho Health Sciences University","ror":"https://ror.org/003hsr719","country_code":"ZA","type":"education","lineage":["https://openalex.org/I2802393258"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Nonkululeko Magagula","raw_affiliation_strings":["Diarrhoeal Pathogens Research Unit, Department of Virology, Sefako Makgatho Health Sciences University, Pretoria, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diarrhoeal Pathogens Research Unit, Department of Virology, Sefako Makgatho Health Sciences University, Pretoria, South Africa","institution_ids":["https://openalex.org/I2802393258"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5137120497","display_name":"Kebareng Rakau-Nondela","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802393258","display_name":"Sefako Makgatho Health Sciences University","ror":"https://ror.org/003hsr719","country_code":"ZA","type":"education","lineage":["https://openalex.org/I2802393258"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Kebareng Rakau-Nondela","raw_affiliation_strings":["Diarrhoeal Pathogens Research Unit, Department of Virology, Sefako Makgatho Health Sciences University, Pretoria, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diarrhoeal Pathogens Research Unit, Department of Virology, Sefako Makgatho Health Sciences University, Pretoria, South Africa","institution_ids":["https://openalex.org/I2802393258"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042781842","display_name":"T\u00falio Machado Fumian","orcid":"https://orcid.org/0000-0001-9654-0172","observed_orcids":["https://orcid.org/0000-0001-9654-0172"]},"institutions":[{"id":"https://openalex.org/I4405286966","display_name":"Instituto Oswaldo Cruz","ror":"https://ror.org/03pww0c55","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405286966","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Tulio M. Fumian","raw_affiliation_strings":["Instituto Oswaldo Cruz, Funda\u00e7\u00e3o Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil"],"raw_orcid":"https://orcid.org/0000-0001-9654-0172","affiliations":[{"raw_affiliation_string":"Instituto Oswaldo Cruz, Funda\u00e7\u00e3o Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405286966","https://openalex.org/I52325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5137084937","display_name":"Irene T.A. Maciel","orcid":"https://orcid.org/0009-0002-3700-3814","observed_orcids":["https://orcid.org/0009-0002-3700-3814"]},"institutions":[{"id":"https://openalex.org/I4405286966","display_name":"Instituto Oswaldo Cruz","ror":"https://ror.org/03pww0c55","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405286966","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Irene T.A. Maciel","raw_affiliation_strings":["Instituto Oswaldo Cruz, Funda\u00e7\u00e3o Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto Oswaldo Cruz, Funda\u00e7\u00e3o Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405286966","https://openalex.org/I52325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5137164640","display_name":"Elena Samoilovich","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elena Samoilovich","raw_affiliation_strings":["Republican Center for Hygiene, Epidemiology and Public Health, Minsk, Belarus"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Republican Center for Hygiene, Epidemiology and Public Health, Minsk, Belarus","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020917263","display_name":"Galina Valeryevna Semeiko","orcid":"https://orcid.org/0000-0002-2170-3579","observed_orcids":["https://orcid.org/0000-0002-2170-3579"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Galina Semeiko","raw_affiliation_strings":["Republican Center for Hygiene, Epidemiology and Public Health, Minsk, Belarus"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Republican Center for Hygiene, Epidemiology and Public Health, Minsk, Belarus","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020250905","display_name":"Tintu Varghese","orcid":"https://orcid.org/0000-0001-5246-5043","observed_orcids":["https://orcid.org/0000-0001-5246-5043"]},"institutions":[{"id":"https://openalex.org/I172917736","display_name":"Christian Medical College, Vellore","ror":"https://ror.org/00c7kvd80","country_code":"IN","type":"education","lineage":["https://openalex.org/I172917736"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Tintu Varghese","raw_affiliation_strings":["Christian Medical College, Vellore, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Christian Medical College, Vellore, India","institution_ids":["https://openalex.org/I172917736"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104333220","display_name":"Sarah Thomas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210150290","display_name":"Murdoch Children's Research Institute","ror":"https://ror.org/048fyec77","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I4210150290"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Sarah Thomas","raw_affiliation_strings":["Murdoch Children\u2019s Research Institute, Melbourne, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Murdoch Children\u2019s Research Institute, Melbourne, Australia","institution_ids":["https://openalex.org/I4210150290"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007425462","display_name":"Julie E. Bines","orcid":"https://orcid.org/0000-0002-5452-6601","observed_orcids":["https://orcid.org/0000-0002-5452-6601"]},"institutions":[{"id":"https://openalex.org/I4210150290","display_name":"Murdoch Children's Research Institute","ror":"https://ror.org/048fyec77","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I4210150290"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Julie E. Bines","raw_affiliation_strings":["Murdoch Children\u2019s Research Institute, Melbourne, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Murdoch Children\u2019s Research Institute, Melbourne, Australia","institution_ids":["https://openalex.org/I4210150290"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090074672","display_name":"Dandi Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210140986","display_name":"National Institute for Viral Disease Control and Prevention","ror":"https://ror.org/04b1sh213","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210140986","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dandi Li","raw_affiliation_strings":["National Institute for Viral Disease Control and Prevention, China CDC, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute for Viral Disease Control and Prevention, China CDC, Beijing, China","institution_ids":["https://openalex.org/I184490438","https://openalex.org/I4210140986"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071816628","display_name":"Furqan Kabir","orcid":"https://orcid.org/0000-0001-9564-4607","observed_orcids":["https://orcid.org/0000-0001-9564-4607"]},"institutions":[{"id":"https://openalex.org/I118185606","display_name":"Aga Khan University","ror":"https://ror.org/03gd0dm95","country_code":"PK","type":"education","lineage":["https://openalex.org/I118185606","https://openalex.org/I4210114929"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Furqan Kabir","raw_affiliation_strings":["Infectious Diseases Research Laboratory, Aga Khan University, Karachi, Pakistan"],"raw_orcid":"https://orcid.org/0000-0001-9564-4607","affiliations":[{"raw_affiliation_string":"Infectious Diseases Research Laboratory, Aga Khan University, Karachi, Pakistan","institution_ids":["https://openalex.org/I118185606"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007061685","display_name":"Eric R. Houpt","orcid":"https://orcid.org/0000-0003-1085-1354","observed_orcids":["https://orcid.org/0000-0003-1085-1354"]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric R. Houpt","raw_affiliation_strings":["Division of Infectious Diseases & International Health, University of Virginia, Charlottesville, VA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases & International Health, University of Virginia, Charlottesville, VA, USA","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001149760","display_name":"Mick N. Mulders","orcid":"https://orcid.org/0000-0002-5332-2690","observed_orcids":["https://orcid.org/0000-0002-5332-2690"]},"institutions":[{"id":"https://openalex.org/I4210105654","display_name":"World Health Organization","ror":"https://ror.org/01f80g185","country_code":"CH","type":"government","lineage":["https://openalex.org/I4210105654"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Mick N. Mulders","raw_affiliation_strings":["World Health Organization, Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"World Health Organization, Geneva, Switzerland","institution_ids":["https://openalex.org/I4210105654"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052463521","display_name":"Heidi M. Soeters","orcid":"https://orcid.org/0000-0002-9415-9340","observed_orcids":["https://orcid.org/0000-0002-9415-9340"]},"institutions":[{"id":"https://openalex.org/I4210105654","display_name":"World Health Organization","ror":"https://ror.org/01f80g185","country_code":"CH","type":"government","lineage":["https://openalex.org/I4210105654"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Heidi M. Soeters","raw_affiliation_strings":["World Health Organization, Geneva, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-9415-9340","affiliations":[{"raw_affiliation_string":"World Health Organization, Geneva, Switzerland","institution_ids":["https://openalex.org/I4210105654"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051818098","display_name":"James Alexander Platts-Mills","orcid":"https://orcid.org/0000-0002-4956-0418","observed_orcids":["https://orcid.org/0000-0002-4956-0418"]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James A. Platts-Mills","raw_affiliation_strings":["Division of Infectious Diseases & International Health, University of Virginia, Charlottesville, VA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases & International Health, University of Virginia, Charlottesville, VA, USA","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5152167143","display_name":"the Global Pediatric Diarrhea Surveillance network","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"the Global Pediatric Diarrhea Surveillance network","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":13,"institutions_distinct_count":19,"corresponding_author_ids":["https://openalex.org/A5052463521"],"corresponding_institution_ids":["https://openalex.org/I4210105654"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.6279000043869019,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.6279000043869019,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10943","display_name":"Escherichia coli research studies","score":0.3073999881744385,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10976","display_name":"Viral gastroenteritis research and epidemiology","score":0.031599998474121094,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/shigella-sonnei","display_name":"Shigella sonnei","score":0.8830000162124634},{"id":"https://openalex.org/keywords/shigella-flexneri","display_name":"Shigella flexneri","score":0.9860000014305115},{"id":"https://openalex.org/keywords/childhood-diarrhea","display_name":"childhood diarrhea","score":0.7310000061988831},{"id":"https://openalex.org/keywords/shigella-vaccine","display_name":"Shigella vaccine","score":0.7300000190734863},{"id":"https://openalex.org/keywords/vaccination-coverage","display_name":"vaccination coverage","score":0.5329999923706055},{"id":"https://openalex.org/keywords/shigella-flexneri-2a","display_name":"Shigella flexneri 2a","score":0.7739999890327454},{"id":"https://openalex.org/keywords/low-and-middle-income-countries","display_name":"low- and middle-income countries","score":0.8130000233650208}],"concepts":[{"id":"https://openalex.org/C2781217973","wikidata":"https://www.wikidata.org/wiki/Q1644417","display_name":"Shigella flexneri","level":4,"score":0.8615000247955322},{"id":"https://openalex.org/C2779802037","wikidata":"https://www.wikidata.org/wiki/Q40878","display_name":"Diarrhea","level":2,"score":0.819599986076355},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7402999997138977},{"id":"https://openalex.org/C2776986154","wikidata":"https://www.wikidata.org/wiki/Q131029","display_name":"Shigella","level":4,"score":0.7002000212669373},{"id":"https://openalex.org/C2911111840","wikidata":"https://www.wikidata.org/wiki/Q6382438","display_name":"Shigella sonnei","level":5,"score":0.6947000026702881},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.6496999859809875},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.6104000210762024},{"id":"https://openalex.org/C10389963","wikidata":"https://www.wikidata.org/wiki/Q848328","display_name":"Serotype","level":2,"score":0.5782999992370605},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.5570999979972839},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.46939998865127563},{"id":"https://openalex.org/C2778750513","wikidata":"https://www.wikidata.org/wiki/Q1142751","display_name":"Norovirus","level":3,"score":0.4198000133037567},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.3628999888896942},{"id":"https://openalex.org/C2779546430","wikidata":"https://www.wikidata.org/wiki/Q327298","display_name":"Shigellosis","level":5,"score":0.34150001406669617},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.3149000108242035},{"id":"https://openalex.org/C2780708024","wikidata":"https://www.wikidata.org/wiki/Q129279","display_name":"Dysentery","level":2,"score":0.30140000581741333},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.28040000796318054},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2775000035762787},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.2703999876976013},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.26100000739097595},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.2587999999523163},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.2547999918460846},{"id":"https://openalex.org/C2781081971","wikidata":"https://www.wikidata.org/wiki/Q7883042","display_name":"Under-five","level":2,"score":0.25209999084472656}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.09.14.26363009","doi":"https://doi.org/10.64898/2026.09.14.26363009","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.14.26363009","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/15/2026.09.14.26363009.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.64898/2026.09.14.26363009","doi":"https://doi.org/10.64898/2026.09.14.26363009","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.14.26363009","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/15/2026.09.14.26363009.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320307856","display_name":"World Health Organization","ror":"https://ror.org/01f80g185"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7213324796.pdf","grobid_xml":"https://content.openalex.org/works/W7213324796.grobid-xml"},"referenced_works_count":22,"referenced_works":["https://openalex.org/W2114053580","https://openalex.org/W2166293389","https://openalex.org/W2521607002","https://openalex.org/W2626858578","https://openalex.org/W2767349396","https://openalex.org/W2892815535","https://openalex.org/W3108880818","https://openalex.org/W3199419853","https://openalex.org/W4211093840","https://openalex.org/W4293224667","https://openalex.org/W4294636642","https://openalex.org/W4318612361","https://openalex.org/W4320719825","https://openalex.org/W4366352318","https://openalex.org/W4383186798","https://openalex.org/W4387475870","https://openalex.org/W4387693423","https://openalex.org/W4393167147","https://openalex.org/W4394821633","https://openalex.org/W7135040888","https://openalex.org/W7136330656","https://openalex.org/W7163159111"],"related_works":["https://openalex.org/W4400723753","https://openalex.org/W7171563752","https://openalex.org/W4393167023","https://openalex.org/W4413105904","https://openalex.org/W1996668559","https://openalex.org/W4408938359","https://openalex.org/W4413313102","https://openalex.org/W2123227667","https://openalex.org/W2114396788","https://openalex.org/W7162516467"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Shigella":[2,27,152,179,204,242,262,280],"is":[3,54],"a":[4,55,102],"leading":[5],"cause":[6,246],"of":[7,20,26,37,64,105,125,141,161,166,178,233,241,247,257,289],"diarrhea":[8,43,66,77,181,251,291],"in":[9,11,44,83,169,194,200,224,252,264,277],"children":[10,68,74,92,134,170],"low-":[12],"and":[13,35,40,114,123,216,270],"middle-income":[14],"countries":[15],"(LMICs).":[16],"Optimizing":[17],"the":[18,32,45,62,239,248],"impact":[19],"vaccines":[21,263],"necessitates":[22],"an":[23,228,244],"accurate":[24],"characterization":[25],"serotype":[28],"prevalence.":[29],"We":[30,118],"describe":[31],"burden,":[33],"epidemiology":[34],"characteristics":[36],"S.":[38,41,112,115,208,213,219],"sonnei":[39,113,209],"flexneri":[42,116,214,220],"Global":[46],"Pediatric":[47],"Diarrhea":[48],"Surveillance":[49],"(GPDS)":[50],"network.":[51],"Methods":[52],"GPDS":[53,72,131],"World":[56],"Health":[57],"Organization-coordinated":[58],"surveillance":[59,81],"network":[60],"investigating":[61],"etiology":[63],"hospitalized":[65,75,138,162,290],"among":[67],"aged":[69,135,171],"<5":[70,136],"years.":[71],"enrolls":[73],"with":[76,139,164],"at":[78],"38":[79],"sentinel":[80],"sites":[82],"31":[84],"LMICs.":[85],"Randomly":[86],"selected":[87,147],"stool":[88],"specimens":[89],"from":[90,184,286],"these":[91,271],"were":[93,145,207,212,218],"tested":[94],"by":[95,261,268],"quantitative":[96],"polymerase":[97],"chain":[98],"reaction":[99],"to":[100,110,196,231],"detect":[101],"broad":[103],"range":[104],"enteropathogens":[106],"as":[107,109,243],"well":[108],"identify":[111],"serotypes.":[117],"estimated":[119,175,229],"pathogen-specific":[120],"attributable":[121,176],"fractions":[122],"incidence":[124,177],"diarrheal":[126],"hospitalizations.":[127],"Results":[128],"During":[129],"2017\u20132022,":[130],"enrolled":[132],"70,750":[133],"years":[137,193],"diarrhea,":[140,163],"which":[142],"16,458":[143],"(23.3%)":[144],"randomly":[146],"for":[148],"qPCR":[149],"testing.":[150],"Globally,":[151],"caused":[153],"9.8%":[154],"(95%":[155,186],"Confidence":[156],"Interval":[157],"[CI]:":[158],"8.4,":[159],"11.3)":[160],"28.3%":[165],"cases":[167],"occurring":[168],"\u226412":[172],"months.":[173],"The":[174,255],"-associated":[180],"hospitalizations":[182],"decreased":[183],"1.27":[185],"CI:":[187],"0.95,":[188],"1.64)":[189],"per":[190],"1,000":[191],"child":[192],"2017\u20132018":[195],"0.88":[197],"(0.67,":[198],"1.10)":[199],"2021\u20132022.":[201],"Among":[202],"typeable":[203],"cases,":[205],"34.8%":[206],",":[210],"24.2%":[211],"2a,":[215],"9.9%":[217],"1b.":[221],"Vaccines":[222],"currently":[223],"development":[225,266],"would":[226],"cover":[227],"59.0%":[230],"72.2%":[232],"cases.":[234],"Conclusions":[235],"These":[236],"findings":[237],"support":[238],"role":[240],"important":[245],"most":[249],"severe":[250],"young":[253],"children.":[254],"breadth":[256],"homotypic":[258],"protection":[259],"provided":[260],"clinical":[265,294],"varied":[267],"region,":[269],"broadly":[272],"representative":[273],"data":[274],"can":[275],"aid":[276],"prioritization.":[278],"Non-dysenteric":[279],"could":[281],"not":[282],"be":[283],"readily":[284],"differentiated":[285],"other":[287],"causes":[288],"based":[292],"on":[293],"characteristics.":[295]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-09-16T00:00:00"}