{"id":"https://openalex.org/W7213239798","doi":"https://doi.org/10.1093/ejendo/lvag096.660","title":"EP51 - ECE_3020 - Role of glucocorticoid receptor polymorphisms on blood pressure control and lipid profile in a group of patients with apparent essential hypertension","display_name":"EP51 - ECE_3020 - Role of glucocorticoid receptor polymorphisms on blood pressure control and lipid profile in a group of patients with apparent essential hypertension","publication_year":2026,"publication_date":"2026-08-01","ids":{"openalex":"https://openalex.org/W7213239798","doi":"https://doi.org/10.1093/ejendo/lvag096.660"},"language":"en","primary_location":{"id":"doi:10.1093/ejendo/lvag096.660","doi":"https://doi.org/10.1093/ejendo/lvag096.660","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ejendo/lvag096.660","pdf_url":"https://academic.oup.com/ejendo/article-pdf/195/Supplement_1/lvag096.660/70596273/lvag096.660.pdf","source":{"id":"https://openalex.org/S4210218062","display_name":"European Journal of Endocrinology","issn_l":"0804-4643","issn":["0804-4643","1479-683X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Endocrinology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/ejendo/article-pdf/195/Supplement_1/lvag096.660/70596273/lvag096.660.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103107044","display_name":"Antonio Musolino","orcid":"https://orcid.org/0000-0002-3316-957X","observed_orcids":["https://orcid.org/0000-0002-3316-957X"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonio Musolino","raw_affiliation_strings":["Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089714383","display_name":"Chiara Parazzoli","orcid":"https://orcid.org/0000-0002-6789-3961","observed_orcids":["https://orcid.org/0000-0002-6789-3961"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210094195","display_name":"Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda","ror":"https://ror.org/00htrxv69","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094195"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Chiara Parazzoli","raw_affiliation_strings":["ASST Grande Ospedale Metropolitano Niguarda, Unit of Endocrinology , Milano ,","Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ASST Grande Ospedale Metropolitano Niguarda, Unit of Endocrinology , Milano ,","institution_ids":["https://openalex.org/I4210094195"]},{"raw_affiliation_string":"Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114543151","display_name":"Elisa Delle Donne","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210134201","display_name":"IRCCS Istituto Auxologico Italiano","ror":"https://ror.org/033qpss18","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210134201","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Elisa Delle Donne","raw_affiliation_strings":["Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,","Endocrinology Department & Lab of Endocrine and Metabolic Research, Istituto Auxologico Italiano IRCCS , Milan ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,","institution_ids":["https://openalex.org/I189158943"]},{"raw_affiliation_string":"Endocrinology Department & Lab of Endocrine and Metabolic Research, Istituto Auxologico Italiano IRCCS , Milan ,","institution_ids":["https://openalex.org/I4210134201"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012966577","display_name":"Vittoria Favero","orcid":"https://orcid.org/0000-0001-6109-423X","observed_orcids":["https://orcid.org/0000-0001-6109-423X"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210094195","display_name":"Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda","ror":"https://ror.org/00htrxv69","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094195"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Vittoria Favero","raw_affiliation_strings":["ASST Grande Ospedale Metropolitano Niguarda, Unit of Endocrinology , Milano ,","Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ASST Grande Ospedale Metropolitano Niguarda, Unit of Endocrinology , Milano ,","institution_ids":["https://openalex.org/I4210094195"]},{"raw_affiliation_string":"Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080104899","display_name":"Carmen Aresta","orcid":"https://orcid.org/0000-0002-5390-2134","observed_orcids":["https://orcid.org/0000-0002-5390-2134"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210094195","display_name":"Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda","ror":"https://ror.org/00htrxv69","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094195"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Carmen Aresta","raw_affiliation_strings":["ASST Grande Ospedale Metropolitano Niguarda, Unit of Endocrinology , Milano ,","Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ASST Grande Ospedale Metropolitano Niguarda, Unit of Endocrinology , Milano ,","institution_ids":["https://openalex.org/I4210094195"]},{"raw_affiliation_string":"Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042764318","display_name":"Grzegorz Bilo","orcid":"https://orcid.org/0000-0002-5104-9176","observed_orcids":["https://orcid.org/0000-0002-5104-9176"]},"institutions":[{"id":"https://openalex.org/I4210134201","display_name":"IRCCS Istituto Auxologico Italiano","ror":"https://ror.org/033qpss18","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210134201","https://openalex.org/I4210153126"]},{"id":"https://openalex.org/I66752286","display_name":"University of Milano-Bicocca","ror":"https://ror.org/01ynf4891","country_code":"IT","type":"education","lineage":["https://openalex.org/I66752286"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Grzegorz Bilo","raw_affiliation_strings":["Department of Cardiology, Istituto Auxologico Italiano IRCCS , Milan ,","Department of Medicine and Surgery, University of Milano-Bicocca , Milan ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Istituto Auxologico Italiano IRCCS , Milan ,","institution_ids":["https://openalex.org/I4210134201"]},{"raw_affiliation_string":"Department of Medicine and Surgery, University of Milano-Bicocca , Milan ,","institution_ids":["https://openalex.org/I66752286"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075658806","display_name":"Alessandro Croce","orcid":"https://orcid.org/0000-0003-3547-1913","observed_orcids":["https://orcid.org/0000-0003-3547-1913"]},"institutions":[{"id":"https://openalex.org/I4210134201","display_name":"IRCCS Istituto Auxologico Italiano","ror":"https://ror.org/033qpss18","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210134201","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alessandro Croce","raw_affiliation_strings":["Department of Cardiology, Istituto Auxologico Italiano IRCCS , Milan ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Istituto Auxologico Italiano IRCCS , Milan ,","institution_ids":["https://openalex.org/I4210134201"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058188020","display_name":"Martino Francesco Pengo","orcid":"https://orcid.org/0000-0002-4657-9172","observed_orcids":["https://orcid.org/0000-0002-4657-9172"]},"institutions":[{"id":"https://openalex.org/I4210134201","display_name":"IRCCS Istituto Auxologico Italiano","ror":"https://ror.org/033qpss18","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210134201","https://openalex.org/I4210153126"]},{"id":"https://openalex.org/I66752286","display_name":"University of Milano-Bicocca","ror":"https://ror.org/01ynf4891","country_code":"IT","type":"education","lineage":["https://openalex.org/I66752286"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Martino Pengo","raw_affiliation_strings":["Department of Cardiology, Istituto Auxologico Italiano IRCCS , Milan ,","Department of Medicine and Surgery, University of Milano-Bicocca , Milan ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Istituto Auxologico Italiano IRCCS , Milan ,","institution_ids":["https://openalex.org/I4210134201"]},{"raw_affiliation_string":"Department of Medicine and Surgery, University of Milano-Bicocca , Milan ,","institution_ids":["https://openalex.org/I66752286"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015206826","display_name":"Gianfranco Parati","orcid":"https://orcid.org/0000-0001-9402-7439","observed_orcids":["https://orcid.org/0000-0001-9402-7439"]},"institutions":[{"id":"https://openalex.org/I4210134201","display_name":"IRCCS Istituto Auxologico Italiano","ror":"https://ror.org/033qpss18","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210134201","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gianfranco Parati","raw_affiliation_strings":["Department of Cardiology, Istituto Auxologico Italiano IRCCS , Milan ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Istituto Auxologico Italiano IRCCS , Milan ,","institution_ids":["https://openalex.org/I4210134201"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030477521","display_name":"Luca Persani","orcid":"https://orcid.org/0000-0003-2068-9581","observed_orcids":["https://orcid.org/0000-0003-2068-9581"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210134201","display_name":"IRCCS Istituto Auxologico Italiano","ror":"https://ror.org/033qpss18","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210134201","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Luca Persani","raw_affiliation_strings":["Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,","Endocrinology Department & Lab of Endocrine and Metabolic Research, Istituto Auxologico Italiano IRCCS , Milan ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,","institution_ids":["https://openalex.org/I189158943"]},{"raw_affiliation_string":"Endocrinology Department & Lab of Endocrine and Metabolic Research, Istituto Auxologico Italiano IRCCS , Milan ,","institution_ids":["https://openalex.org/I4210134201"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061311286","display_name":"Alfredo Scillitani","orcid":"https://orcid.org/0000-0001-9954-4187","observed_orcids":["https://orcid.org/0000-0001-9954-4187"]},"institutions":[{"id":"https://openalex.org/I2800188116","display_name":"Casa Sollievo della Sofferenza","ror":"https://ror.org/00md77g41","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2800188116","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alfredo Scillitani","raw_affiliation_strings":["Casa Sollievo della Sofferenza, Unit of Endocrinology , San Giovanni Rotondo ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Casa Sollievo della Sofferenza, Unit of Endocrinology , San Giovanni Rotondo ,","institution_ids":["https://openalex.org/I2800188116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013529369","display_name":"Biagio Cangiano","orcid":"https://orcid.org/0000-0002-2658-744X","observed_orcids":["https://orcid.org/0000-0002-2658-744X"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210134201","display_name":"IRCCS Istituto Auxologico Italiano","ror":"https://ror.org/033qpss18","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210134201","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Biagio Cangiano","raw_affiliation_strings":["Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,","Endocrinology Department & Lab of Endocrine and Metabolic Research, Istituto Auxologico Italiano IRCCS , Milan ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,","institution_ids":["https://openalex.org/I189158943"]},{"raw_affiliation_string":"Endocrinology Department & Lab of Endocrine and Metabolic Research, Istituto Auxologico Italiano IRCCS , Milan ,","institution_ids":["https://openalex.org/I4210134201"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026110667","display_name":"Gabriele Pogliaghi","orcid":"https://orcid.org/0000-0002-8025-1322","observed_orcids":["https://orcid.org/0000-0002-8025-1322"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210134201","display_name":"IRCCS Istituto Auxologico Italiano","ror":"https://ror.org/033qpss18","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210134201","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gabriele Pogliaghi","raw_affiliation_strings":["Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,","Endocrinology Department & Lab of Endocrine and Metabolic Research, Istituto Auxologico Italiano IRCCS , Milan ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,","institution_ids":["https://openalex.org/I189158943"]},{"raw_affiliation_string":"Endocrinology Department & Lab of Endocrine and Metabolic Research, Istituto Auxologico Italiano IRCCS , Milan ,","institution_ids":["https://openalex.org/I4210134201"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030957556","display_name":"Ilaria Gentile","orcid":"https://orcid.org/0000-0002-5407-4588","observed_orcids":["https://orcid.org/0000-0002-5407-4588"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210134201","display_name":"IRCCS Istituto Auxologico Italiano","ror":"https://ror.org/033qpss18","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210134201","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Ilaria Gentile","raw_affiliation_strings":["Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,","Endocrinology Department & Lab of Endocrine and Metabolic Research, Istituto Auxologico Italiano IRCCS , Milan ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,","institution_ids":["https://openalex.org/I189158943"]},{"raw_affiliation_string":"Endocrinology Department & Lab of Endocrine and Metabolic Research, Istituto Auxologico Italiano IRCCS , Milan ,","institution_ids":["https://openalex.org/I4210134201"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084310173","display_name":"Iacopo Chiodini","orcid":"https://orcid.org/0000-0001-7594-3300","observed_orcids":["https://orcid.org/0000-0001-7594-3300"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210094195","display_name":"Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda","ror":"https://ror.org/00htrxv69","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094195"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Iacopo Chiodini","raw_affiliation_strings":["ASST Grande Ospedale Metropolitano Niguarda, Unit of Endocrinology , Milano ,","Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ASST Grande Ospedale Metropolitano Niguarda, Unit of Endocrinology , Milano ,","institution_ids":["https://openalex.org/I4210094195"]},{"raw_affiliation_string":"Department of Medical Biotechnology and Translational Medicine, University of Milan , Milan ,","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010082387","display_name":"Valentina Morelli","orcid":"https://orcid.org/0000-0002-6716-3045","observed_orcids":["https://orcid.org/0000-0002-6716-3045"]},"institutions":[{"id":"https://openalex.org/I4210134201","display_name":"IRCCS Istituto Auxologico Italiano","ror":"https://ror.org/033qpss18","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210134201","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Valentina Morelli","raw_affiliation_strings":["Endocrinology Department & Lab of Endocrine and Metabolic Research, Istituto Auxologico Italiano IRCCS , Milan ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Endocrinology Department & Lab of Endocrine and Metabolic Research, Istituto Auxologico Italiano IRCCS , Milan ,","institution_ids":["https://openalex.org/I4210134201"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3798,"currency":"EUR","value_usd":4292},"apc_paid":{"value":3798,"currency":"EUR","value_usd":4292},"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"195","issue":"Supplement_1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11839","display_name":"Hormonal Regulation and Hypertension","score":0.8726000189781189,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11839","display_name":"Hormonal Regulation and Hypertension","score":0.8726000189781189,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.09780000150203705,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":0.009200000204145908,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glucocorticoid-resistance","display_name":"glucocorticoid resistance","score":0.8679999709129333},{"id":"https://openalex.org/keywords/glucocorticoid-sensitivity","display_name":"glucocorticoid sensitivity","score":0.8859999775886536},{"id":"https://openalex.org/keywords/bcli-polymorphism","display_name":"BclI polymorphism","score":0.7889999747276306},{"id":"https://openalex.org/keywords/n363s-polymorphism","display_name":"N363S polymorphism","score":0.9390000104904175},{"id":"https://openalex.org/keywords/er22-23ek-polymorphism","display_name":"ER22/23EK polymorphism","score":0.8949999809265137},{"id":"https://openalex.org/keywords/carotid-stenosis","display_name":"carotid artery stenosis","score":0.8600000143051147},{"id":"https://openalex.org/keywords/carotid-intima-media-thickness","display_name":"carotid intima-media thickness","score":0.9800000190734863},{"id":"https://openalex.org/keywords/hypothalamic-pituitary-adrenal-axis","display_name":"hypothalamic-pituitary-adrenal axis","score":0.7760000228881836},{"id":"https://openalex.org/keywords/cortisol","display_name":"cortisol","score":0.5189999938011169},{"id":"https://openalex.org/keywords/lipid-profile","display_name":"lipid profile","score":0.7049999833106995},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"blood pressure","score":0.5059999823570251}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8460999727249146},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8167999982833862},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7818999886512756},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.7630000114440918},{"id":"https://openalex.org/C2777097880","wikidata":"https://www.wikidata.org/wiki/Q988405","display_name":"Essential hypertension","level":3,"score":0.6348000168800354},{"id":"https://openalex.org/C2778270857","wikidata":"https://www.wikidata.org/wiki/Q2723972","display_name":"Lipid profile","level":3,"score":0.6080999970436096},{"id":"https://openalex.org/C149323552","wikidata":"https://www.wikidata.org/wiki/Q3090739","display_name":"Ambulatory blood pressure","level":3,"score":0.6039999723434448},{"id":"https://openalex.org/C59493245","wikidata":"https://www.wikidata.org/wiki/Q14877410","display_name":"Glucocorticoid receptor","level":3,"score":0.5497999787330627},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.5375000238418579},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.4611000120639801},{"id":"https://openalex.org/C2780841215","wikidata":"https://www.wikidata.org/wiki/Q422549","display_name":"Glucocorticoid","level":2,"score":0.4392000138759613},{"id":"https://openalex.org/C61427482","wikidata":"https://www.wikidata.org/wiki/Q6656244","display_name":"Anthropometry","level":2,"score":0.41370001435279846},{"id":"https://openalex.org/C2780473172","wikidata":"https://www.wikidata.org/wiki/Q5572518","display_name":"Glycemic","level":3,"score":0.41339999437332153},{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.3781000077724457},{"id":"https://openalex.org/C2778709874","wikidata":"https://www.wikidata.org/wiki/Q190875","display_name":"Hydrocortisone","level":2,"score":0.37139999866485596},{"id":"https://openalex.org/C2778535154","wikidata":"https://www.wikidata.org/wiki/Q5889863","display_name":"Homeostatic model assessment","level":4,"score":0.3422999978065491},{"id":"https://openalex.org/C2992203999","wikidata":"https://www.wikidata.org/wiki/Q1940733","display_name":"Mean blood pressure","level":4,"score":0.33869999647140503},{"id":"https://openalex.org/C139572402","wikidata":"https://www.wikidata.org/wiki/Q4927820","display_name":"Blood lipids","level":3,"score":0.3077000081539154},{"id":"https://openalex.org/C2781203188","wikidata":"https://www.wikidata.org/wiki/Q1676817","display_name":"Microalbuminuria","level":3,"score":0.3046000003814697},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.30390000343322754},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.29899999499320984},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.2854999899864197},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.2824999988079071},{"id":"https://openalex.org/C2780192228","wikidata":"https://www.wikidata.org/wiki/Q575890","display_name":"Antihypertensive drug","level":3,"score":0.27970001101493835},{"id":"https://openalex.org/C17140001","wikidata":"https://www.wikidata.org/wiki/Q1759415","display_name":"Pulse pressure","level":3,"score":0.27230000495910645},{"id":"https://openalex.org/C2777693730","wikidata":"https://www.wikidata.org/wiki/Q1140549","display_name":"Abdominal obesity","level":4,"score":0.25949999690055847},{"id":"https://openalex.org/C35785553","wikidata":"https://www.wikidata.org/wiki/Q756720","display_name":"Ambulatory","level":2,"score":0.2547000050544739},{"id":"https://openalex.org/C2778525890","wikidata":"https://www.wikidata.org/wiki/Q184564","display_name":"Aldosterone","level":2,"score":0.25429999828338623}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1093/ejendo/lvag096.660","doi":"https://doi.org/10.1093/ejendo/lvag096.660","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ejendo/lvag096.660","pdf_url":"https://academic.oup.com/ejendo/article-pdf/195/Supplement_1/lvag096.660/70596273/lvag096.660.pdf","source":{"id":"https://openalex.org/S4210218062","display_name":"European Journal of Endocrinology","issn_l":"0804-4643","issn":["0804-4643","1479-683X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Endocrinology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1093/ejendo/lvag096.660","doi":"https://doi.org/10.1093/ejendo/lvag096.660","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ejendo/lvag096.660","pdf_url":"https://academic.oup.com/ejendo/article-pdf/195/Supplement_1/lvag096.660/70596273/lvag096.660.pdf","source":{"id":"https://openalex.org/S4210218062","display_name":"European Journal of Endocrinology","issn_l":"0804-4643","issn":["0804-4643","1479-683X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Endocrinology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7213239798.pdf","grobid_xml":"https://content.openalex.org/works/W7213239798.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2519938852","https://openalex.org/W1522848728","https://openalex.org/W2240794472","https://openalex.org/W2005190469","https://openalex.org/W2090352420","https://openalex.org/W2384508134","https://openalex.org/W2122827898","https://openalex.org/W2118609987","https://openalex.org/W2252874428","https://openalex.org/W4236152596"],"abstract_inverted_index":{"Abstract":[0],"Objective":[1],"four":[2],"glucocorticoid":[3],"receptor":[4],"polymorphisms":[5],"(GRp)":[6],"have":[7],"been":[8],"linked":[9,402],"with":[10,52,233,303,398,403],"increased":[11],"resistance":[12],"(ER22/23EK,":[13],"GR-9\u03b2)":[14],"or":[15,25,122,152,164],"sensitivity":[16],"(N363S,":[17],"BclI)":[18],"to":[19,38,191],"glucocorticoids":[20],"(GC)":[21],"conferring":[22],"a":[23,48,161,276,421],"better,":[24],"worse,":[26],"metabolic":[27],"and":[28,42,94,101,138,148,204,244,270,288,336],"cardiovascular":[29,408],"risk.":[30],"The":[31],"aim":[32],"of":[33,45,50,103,107,134,150,160,172,184,251,263,279,310,315,321,424],"the":[34,40,170,211,222,261],"present":[35],"study":[36],"was":[37,210,221,301,418],"evaluate":[39],"biochemical":[41],"clinical":[43],"impact":[44],"GRp":[46,185,214],"in":[47,57,63,215,240,260,354,371,384],"group":[49],"patients":[51,66,179,207,227,232,274,325,374,414],"apparent":[53],"essential":[54],"hypertension.":[55],"Methods":[56],"this":[58],"cross-sectional":[59],"study,":[60],"we":[61,196,362],"evaluated":[62],"99":[64],"hypertensive":[65],"(aged":[67],"37-70":[68],"years,":[69],"51":[70],"females):":[71],"anthropometric":[72,241],"variables;":[73],"hypotalamus-pituitary-adrenal":[74],"(HPA)":[75],"axis":[76,248],"parameters":[77],"[(basal":[78],"cortisol":[79,81,91],"levels,":[80,88],"after":[82],"1":[83],"mg-Dexamethasone":[84],"suppression":[85],"test,":[86],"ACTH":[87,328],"urinary":[89],"free":[90],"(UFC)];":[92],"glycemic":[93,243],"lipidic":[95,245],"profile;":[96],"carotid":[97,104,280],"intima-media":[98],"thickness":[99],"(cIMT)":[100],"presence":[102,106,149,171],"stenosis;":[105],"uncontrolled":[108],"blood":[109,119],"pressure":[110,120],"(UBP)":[111],"defined":[112,157],"as":[113,158],"24":[114],"h-mean":[115],"BP":[116,125],"at":[117,173],"ambulatory":[118],"monitoring":[121],"mean":[123],"office":[124],">":[126],"140/90":[127],"mmHg":[128],"despite":[129],"antihypertensive":[130,252,316],"treatment;":[131],"gene":[132],"variants":[133],"ER22/23EK,":[135],"GR-9\u03b2,":[136],"N363S":[137],"BclI.":[139],"Exclusion":[140],"criteria":[141],"were":[142,156,186,238],"signs":[143],"suggestive":[144],"for":[145,360],"secondary":[146],"hypertension":[147],"obesity":[151],"diabetes":[153],"mellitus.":[154],"Patients":[155],"carriers":[159],"resistant":[162],"(RS)":[163],"sensitive":[165],"(SN)":[166],"phenotype":[167,193,300],"based":[168],"on":[169,426],"least":[174],"one":[175],"associated":[176,302,397],"GRp.":[177],"Thirteen":[178],"who":[180],"presented":[181],"both":[182],"types":[183],"excluded":[187],"from":[188,406],"statistical":[189],"analysis":[190],"avoid":[192],"overlapping.":[194],"Results":[195],"found":[197,239,363],"32":[198],"RS":[199,216,231,273,299],"(32.3%),":[200],"54":[201],"SN":[202,226,324,373,413],"(54.5%)":[203],"26":[205],"wild-type":[206],"(26.3%).":[208],"GR-9\u03b2":[209,395],"most":[212,223],"prevalent":[213,224],"(32/32":[217],"cases)":[218],"while":[219],"BclI":[220],"among":[225],"(52/54":[228],"cases).":[229],"Comparing":[230],"non-RS":[234,297],"patients,":[235],"no":[236],"differences":[237],"variables,":[242],"profile,":[246],"HPA":[247],"parameters,":[249],"number":[250,314],"drugs.":[253],"We":[254,346],"did":[255,347],"not":[256,348,383],"observe":[257],"any":[258,350,355],"difference":[259,353],"prevalence":[262,278,320],"impaired":[264],"fasting":[265],"glucose/impaired":[266],"glucose":[267],"tolerance":[268],"(IFG/IGT)":[269],"altered":[271],"cIMT.":[272],"showed":[275,326],"higher":[277,337,415],"stenosis":[281],"(36%":[282],"vs":[283,291,330,376,388],"61%,":[284],"P":[285,293,306,333,379,391],"=":[286,294,307,334,341,380,392],".056)":[287],"UBP":[289,304,404],"(34.3%":[290],"63.2%,":[292],".024)":[295],"than":[296,343],"patients.":[298,345],"(OR:5.6,":[305],".007)":[308],"independently":[309,405],"age,":[311],"sex,":[312,361],"BMI,":[313],"drugs,":[317],"smoking":[318],"status,":[319],"IFG/IGT,":[322],"UFC.":[323],"lower":[327],"(30.4":[329],"24.0":[331],"ng/L,":[332],".042)":[335],"HDL":[338,365,416],"cholesterol":[339,366,417],"(P":[340],".043)":[342],"non-SN":[344],"find":[349],"statistically":[351,369],"significant":[352,370],"other":[356],"variables.":[357],"After":[358],"stratification":[359],"that":[364],"levels":[367],"remained":[368],"female":[372,412],"(57.3":[375],"66.3":[377],"mg/dL,":[378,390],".046)":[381],"but":[382],"male":[385],"ones":[386],"(50":[387],"51.1":[389],".77).":[393],"Conclusions":[394],"polymorphism,":[396],"RS,":[399],"could":[400],"be":[401],"common":[407],"risk":[409],"factors.":[410],"In":[411],"observed,":[419],"suggesting":[420],"sex-dependent":[422],"effect":[423],"GC":[425],"cholesterol.":[427]},"counts_by_year":[],"updated_date":"2026-09-25T08:18:29.962427","created_date":"2026-09-16T00:00:00"}