{"id":"https://openalex.org/W7212937841","doi":"https://doi.org/10.1016/j.bvth.2026.100215","title":"The 2025 McMaster Immune Thrombocytopenia (ITP) Summit: insights from autoimmune hemolytic anemia","display_name":"The 2025 McMaster Immune Thrombocytopenia (ITP) Summit: insights from autoimmune hemolytic anemia","publication_year":2026,"publication_date":"2026-09-14","ids":{"openalex":"https://openalex.org/W7212937841","doi":"https://doi.org/10.1016/j.bvth.2026.100215","pmid":"https://pubmed.ncbi.nlm.nih.gov/42999908","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13744369"},"language":"en","primary_location":{"id":"doi:10.1016/j.bvth.2026.100215","doi":"https://doi.org/10.1016/j.bvth.2026.100215","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bvth.2026.100215","pdf_url":"https://www.sciencedirect.com/science/article/pii/S295032722600080X/pdf","source":{"id":"https://openalex.org/S5407037026","display_name":"Blood Vessels Thrombosis & Hemostasis","issn_l":"2950-3272","issn":["2950-3272"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","ki-jl-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood Vessels, Thrombosis &amp; Hemostasis","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.sciencedirect.com/science/article/pii/S295032722600080X/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011090475","display_name":"Nicole Relke","orcid":"https://orcid.org/0000-0003-3416-6765","observed_orcids":["https://orcid.org/0000-0003-3416-6765"]},"institutions":[{"id":"https://openalex.org/I95297979","display_name":"Canadian Blood Services","ror":"https://ror.org/01jays723","country_code":"CA","type":"funder","lineage":["https://openalex.org/I95297979"]},{"id":"https://openalex.org/I98251732","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29","country_code":"CA","type":"education","lineage":["https://openalex.org/I98251732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Nicole Relke","raw_affiliation_strings":["Department of Medicine, Michael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada","Medical Affairs and Innovation, Canadian Blood Services, Toronto, ON, Canada"],"raw_orcid":"https://orcid.org/0000-0003-3416-6765","affiliations":[{"raw_affiliation_string":"Department of Medicine, Michael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada","institution_ids":["https://openalex.org/I98251732"]},{"raw_affiliation_string":"Medical Affairs and Innovation, Canadian Blood Services, Toronto, ON, Canada","institution_ids":["https://openalex.org/I95297979"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5139616695","display_name":"Fatema Hossain","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98251732","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29","country_code":"CA","type":"education","lineage":["https://openalex.org/I98251732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Fatema Hossain","raw_affiliation_strings":["Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada","Department of Medicine, Michael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada","institution_ids":["https://openalex.org/I98251732"]},{"raw_affiliation_string":"Department of Medicine, Michael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada","institution_ids":["https://openalex.org/I98251732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046108974","display_name":"Saifur Rahman Chowdhury","orcid":"https://orcid.org/0000-0003-4361-0792","observed_orcids":["https://orcid.org/0000-0003-4361-0792"]},"institutions":[{"id":"https://openalex.org/I98251732","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29","country_code":"CA","type":"education","lineage":["https://openalex.org/I98251732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Saifur R. Chowdhury","raw_affiliation_strings":["Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada","Department of Medicine, Michael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada"],"raw_orcid":"https://orcid.org/0000-0003-4361-0792","affiliations":[{"raw_affiliation_string":"Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada","institution_ids":["https://openalex.org/I98251732"]},{"raw_affiliation_string":"Department of Medicine, Michael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada","institution_ids":["https://openalex.org/I98251732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039312835","display_name":"Syed Mahamad","orcid":"https://orcid.org/0000-0002-3496-4591","observed_orcids":["https://orcid.org/0000-0002-3496-4591"]},"institutions":[{"id":"https://openalex.org/I98251732","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29","country_code":"CA","type":"education","lineage":["https://openalex.org/I98251732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Syed Mahamad","raw_affiliation_strings":["Department of Medicine, Michael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada"],"raw_orcid":"https://orcid.org/0000-0002-3496-4591","affiliations":[{"raw_affiliation_string":"Department of Medicine, Michael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada","institution_ids":["https://openalex.org/I98251732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003263508","display_name":"Ali Eshaghpour","orcid":"https://orcid.org/0000-0002-7827-5827","observed_orcids":["https://orcid.org/0000-0002-7827-5827"]},"institutions":[{"id":"https://openalex.org/I98251732","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29","country_code":"CA","type":"education","lineage":["https://openalex.org/I98251732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Ali Eshaghpour","raw_affiliation_strings":["Department of Medicine, Michael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada"],"raw_orcid":"https://orcid.org/0000-0002-7827-5827","affiliations":[{"raw_affiliation_string":"Department of Medicine, Michael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada","institution_ids":["https://openalex.org/I98251732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077478635","display_name":"Douglas B. Cines","orcid":"https://orcid.org/0000-0001-5986-504X","observed_orcids":["https://orcid.org/0000-0001-5986-504X"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Douglas B. Cines","raw_affiliation_strings":["Department of Medicine, Perelam School of Medicine, University of Pennsylvania, PA","Department of Pathology and Laboratory Medicine, Perelam School of Medicine, University of Pennsylvania, PA"],"raw_orcid":"https://orcid.org/0000-0001-5986-504X","affiliations":[{"raw_affiliation_string":"Department of Medicine, Perelam School of Medicine, University of Pennsylvania, PA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Perelam School of Medicine, University of Pennsylvania, PA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105834102","display_name":"Tamam Bakchoul","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8087733","display_name":"University of T\u00fcbingen","ror":"https://ror.org/03a1kwz48","country_code":"DE","type":"education","lineage":["https://openalex.org/I8087733"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Tamam Bakchoul","raw_affiliation_strings":["Centre for Clinical Transfusion Medicine, T\u00fcbingen, Germany","Medical Faculty of T\u00fcbingen, Institute for Clinical and Experimental Transfusion Medicine, University of T\u00fcbingen, T\u00fcbingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Clinical Transfusion Medicine, T\u00fcbingen, Germany","institution_ids":[]},{"raw_affiliation_string":"Medical Faculty of T\u00fcbingen, Institute for Clinical and Experimental Transfusion Medicine, University of T\u00fcbingen, T\u00fcbingen, Germany","institution_ids":["https://openalex.org/I8087733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047512989","display_name":"Shruti Chaturvedi","orcid":"https://orcid.org/0000-0001-6832-2389","observed_orcids":["https://orcid.org/0000-0001-6832-2389"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shruti Chaturvedi","raw_affiliation_strings":["Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029112896","display_name":"Rick Kapur","orcid":"https://orcid.org/0000-0002-1608-876X","observed_orcids":["https://orcid.org/0000-0002-1608-876X"]},"institutions":[{"id":"https://openalex.org/I3020210244","display_name":"Sanquin","ror":"https://ror.org/01fm2fv39","country_code":"NL","type":"nonprofit","lineage":["https://openalex.org/I3020210244"]},{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I887064364","display_name":"University of Amsterdam","ror":"https://ror.org/04dkp9463","country_code":"NL","type":"education","lineage":["https://openalex.org/I887064364"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Rick Kapur","raw_affiliation_strings":["Department of Research, Sanquin Blood Supply Foundation, Amsterdam, The Netherlands","Landsteiner Laboratory, Amsterdam University Medical Center Location University of Amsterdam, Amsterdam, The Netherlands"],"raw_orcid":"https://orcid.org/0000-0002-1608-876X","affiliations":[{"raw_affiliation_string":"Department of Research, Sanquin Blood Supply Foundation, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I3020210244"]},{"raw_affiliation_string":"Landsteiner Laboratory, Amsterdam University Medical Center Location University of Amsterdam, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210151833","https://openalex.org/I887064364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5120724759","display_name":"Sandhya Panch","orcid":"https://orcid.org/0009-0002-2614-1605","observed_orcids":["https://orcid.org/0009-0002-2614-1605"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sandhya Panch","raw_affiliation_strings":["Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA","Division of Hematology/Oncology, University of Washington School of Medicine, Seattle, WA"],"raw_orcid":"https://orcid.org/0009-0002-2614-1605","affiliations":[{"raw_affiliation_string":"Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA","institution_ids":["https://openalex.org/I4210089486"]},{"raw_affiliation_string":"Division of Hematology/Oncology, University of Washington School of Medicine, Seattle, WA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027588079","display_name":"David J. Kuter","orcid":"https://orcid.org/0000-0003-2084-8810","observed_orcids":["https://orcid.org/0000-0003-2084-8810","https://orcid.org/0000-0002-7855-2409"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David J. Kuter","raw_affiliation_strings":["Hematology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027937488","display_name":"Rachael F. Grace","orcid":"https://orcid.org/0000-0001-7302-0449","observed_orcids":["https://orcid.org/0000-0001-7302-0449"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210166317","display_name":"Dana-Farber/Boston Children's Cancer and Blood Disorders Center","ror":"https://ror.org/05k11pb55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113","https://openalex.org/I4210117453","https://openalex.org/I4210166317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rachael F. Grace","raw_affiliation_strings":["Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA"],"raw_orcid":"https://orcid.org/0000-0001-7302-0449","affiliations":[{"raw_affiliation_string":"Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210166317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5148478361","display_name":"Karen Jones","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Karen Jones","raw_affiliation_strings":["wAIHA Warriors (patient advocacy organization), Marion, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"wAIHA Warriors (patient advocacy organization), Marion, OH","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076539221","display_name":"Caroline Kruse","orcid":"https://orcid.org/0000-0003-4259-0988","observed_orcids":["https://orcid.org/0000-0003-4259-0988"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Caroline Kruse","raw_affiliation_strings":["Platelet Disorder Support Association, Cleveland, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Platelet Disorder Support Association, Cleveland, OH","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060383009","display_name":"Mohammad Refaei","orcid":"https://orcid.org/0000-0002-7315-2836","observed_orcids":["https://orcid.org/0000-0002-7315-2836"]},"institutions":[{"id":"https://openalex.org/I98251732","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29","country_code":"CA","type":"education","lineage":["https://openalex.org/I98251732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Mohammad Refaei","raw_affiliation_strings":["Department of Hematology and Thromboembolism, McMaster University, Hamilton, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology and Thromboembolism, McMaster University, Hamilton, ON, Canada","institution_ids":["https://openalex.org/I98251732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084020372","display_name":"Ishac Nazy","orcid":"https://orcid.org/0000-0002-5695-4343","observed_orcids":["https://orcid.org/0000-0002-5695-4343"]},"institutions":[{"id":"https://openalex.org/I98251732","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29","country_code":"CA","type":"education","lineage":["https://openalex.org/I98251732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Ishac Nazy","raw_affiliation_strings":["Department of Medicine, Michael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada"],"raw_orcid":"https://orcid.org/0000-0002-5695-4343","affiliations":[{"raw_affiliation_string":"Department of Medicine, Michael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada","institution_ids":["https://openalex.org/I98251732"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015950115","display_name":"Donald M. Arnold","orcid":"https://orcid.org/0000-0003-0943-8853","observed_orcids":["https://orcid.org/0000-0003-0943-8853"]},"institutions":[{"id":"https://openalex.org/I98251732","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29","country_code":"CA","type":"education","lineage":["https://openalex.org/I98251732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Donald M. Arnold","raw_affiliation_strings":["Department of Medicine, Michael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada"],"raw_orcid":"https://orcid.org/0000-0003-0943-8853","affiliations":[{"raw_affiliation_string":"Department of Medicine, Michael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada","institution_ids":["https://openalex.org/I98251732"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":14,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":{"value":3000,"currency":"USD","value_usd":3000},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.5031752,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"3","issue":"4","first_page":"100215","last_page":"100215"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11660","display_name":"Blood groups and transfusion","score":0.010200000368058681,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/immune-thrombocytopenic-purpura","display_name":"idiopathic thrombocytopenic purpura","score":0.9929999709129333},{"id":"https://openalex.org/keywords/warm-autoimmune-hemolytic-anemia","display_name":"warm autoimmune hemolytic anemia","score":0.9929999709129333},{"id":"https://openalex.org/keywords/autoantibodies","display_name":"autoantibodies","score":0.7950000166893005},{"id":"https://openalex.org/keywords/platelet-clearance","display_name":"platelet clearance","score":0.7620000243186951},{"id":"https://openalex.org/keywords/red-blood-cell-autoantibodies","display_name":"red blood cell autoantibodies","score":0.8550000190734863},{"id":"https://openalex.org/keywords/complement-activation","display_name":"complement activation","score":0.9490000009536743},{"id":"https://openalex.org/keywords/anti-cd20-therapy","display_name":"anti-CD20 therapy","score":0.9100000262260437},{"id":"https://openalex.org/keywords/b-cell-signaling","display_name":"B cell signaling","score":0.8989999890327454},{"id":"https://openalex.org/keywords/plasma-cells","display_name":"plasma cells","score":0.8410000205039978},{"id":"https://openalex.org/keywords/fcrn","display_name":"neonatal Fc receptor","score":0.996999979019165},{"id":"https://openalex.org/keywords/splenomegaly","display_name":"splenomegaly","score":0.8199999928474426},{"id":"https://openalex.org/keywords/patient-experience","display_name":"patient experience","score":0.6819999814033508},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.6150000095367432},{"id":"https://openalex.org/keywords/itp-diagnosis","display_name":"ITP diagnosis","score":0.4790000021457672},{"id":"https://openalex.org/keywords/itp-treatment","display_name":"ITP treatment","score":0.7269999980926514}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8141999840736389},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6514999866485596},{"id":"https://openalex.org/C2910196583","wikidata":"https://www.wikidata.org/wiki/Q638729","display_name":"Autoimmune thrombocytopenia","level":3,"score":0.6236000061035156},{"id":"https://openalex.org/C2993327898","wikidata":"https://www.wikidata.org/wiki/Q638729","display_name":"Immune thrombocytopenia","level":3,"score":0.5842000246047974},{"id":"https://openalex.org/C2779075594","wikidata":"https://www.wikidata.org/wiki/Q8084905","display_name":"Autoimmune disease","level":3,"score":0.555400013923645},{"id":"https://openalex.org/C2777385706","wikidata":"https://www.wikidata.org/wiki/Q28814","display_name":"Autoimmune hemolytic anemia","level":3,"score":0.5453000068664551},{"id":"https://openalex.org/C2776175824","wikidata":"https://www.wikidata.org/wiki/Q1145668","display_name":"Hemolytic anemia","level":2,"score":0.47040000557899475},{"id":"https://openalex.org/C163764329","wikidata":"https://www.wikidata.org/wiki/Q785022","display_name":"Autoantibody","level":3,"score":0.4392000138759613},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.40880000591278076},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.3901999890804291},{"id":"https://openalex.org/C2780130043","wikidata":"https://www.wikidata.org/wiki/Q192360","display_name":"Autoimmunity","level":3,"score":0.3747999966144562},{"id":"https://openalex.org/C2780648854","wikidata":"https://www.wikidata.org/wiki/Q2745824","display_name":"Immunopathology","level":2,"score":0.3427000045776367},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.3257000148296356},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.29030001163482666},{"id":"https://openalex.org/C2778248108","wikidata":"https://www.wikidata.org/wiki/Q5445","display_name":"Anemia","level":2,"score":0.28299999237060547},{"id":"https://openalex.org/C162834538","wikidata":"https://www.wikidata.org/wiki/Q222580","display_name":"Microchimerism","level":4,"score":0.27070000767707825},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.258899986743927}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1016/j.bvth.2026.100215","doi":"https://doi.org/10.1016/j.bvth.2026.100215","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bvth.2026.100215","pdf_url":"https://www.sciencedirect.com/science/article/pii/S295032722600080X/pdf","source":{"id":"https://openalex.org/S5407037026","display_name":"Blood Vessels Thrombosis & Hemostasis","issn_l":"2950-3272","issn":["2950-3272"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","ki-jl-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood Vessels, Thrombosis &amp; Hemostasis","raw_type":"journal-article"},{"id":"pmid:42999908","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42999908","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood vessels, thrombosis & hemostasis","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:6ac0ce3c8500418999efc1552b9b90af","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/6ac0ce3c8500418999efc1552b9b90af","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Blood Vessels, Thrombosis & Hemostasis, Vol 3, Iss 4, Pp 100215- (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.bvth.2026.100215","doi":"https://doi.org/10.1016/j.bvth.2026.100215","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bvth.2026.100215","pdf_url":"https://www.sciencedirect.com/science/article/pii/S295032722600080X/pdf","source":{"id":"https://openalex.org/S5407037026","display_name":"Blood Vessels Thrombosis & Hemostasis","issn_l":"2950-3272","issn":["2950-3272"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","ki-jl-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood Vessels, Thrombosis &amp; Hemostasis","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307105","display_name":"Amgen","ror":"https://ror.org/03g03ge92"},{"id":"https://openalex.org/F4320307115","display_name":"Bristol-Myers Squibb","ror":"https://ror.org/00gtmwv55"},{"id":"https://openalex.org/F4320307758","display_name":"Eli Lilly and Company","ror":"https://ror.org/01qat3289"},{"id":"https://openalex.org/F4320307765","display_name":"Pfizer","ror":"https://ror.org/01xdqrp08"},{"id":"https://openalex.org/F4320307781","display_name":"Sanofi","ror":"https://ror.org/027vj4x92"},{"id":"https://openalex.org/F4320309052","display_name":"Alexion Pharmaceuticals","ror":"https://ror.org/031ywxc85"},{"id":"https://openalex.org/F4320311600","display_name":"Regeneron Pharmaceuticals","ror":"https://ror.org/02f51rf24"},{"id":"https://openalex.org/F4320315426","display_name":"BioCryst","ror":"https://ror.org/031mgj447"},{"id":"https://openalex.org/F4320316629","display_name":"Agios Pharmaceuticals","ror":"https://ror.org/002x06r10"},{"id":"https://openalex.org/F4320318412","display_name":"Argenx","ror":"https://ror.org/04spfxf63"},{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320327470","display_name":"Swedish Orphan Biovitrum","ror":"https://ror.org/04asvbz37"},{"id":"https://openalex.org/F4320332193","display_name":"Genentech","ror":"https://ror.org/04gndp242"},{"id":"https://openalex.org/F4320333003","display_name":"Chugai Pharmaceutical","ror":"https://ror.org/01vepzj85"},{"id":"https://openalex.org/F4320338262","display_name":"Daiichi Sankyo Europe","ror":"https://ror.org/01qhj1g70"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7212937841.pdf","grobid_xml":"https://content.openalex.org/works/W7212937841.grobid-xml"},"referenced_works_count":109,"referenced_works":["https://openalex.org/W1547590503","https://openalex.org/W1931365413","https://openalex.org/W1972148206","https://openalex.org/W1972433111","https://openalex.org/W1974541132","https://openalex.org/W1991437102","https://openalex.org/W1999095358","https://openalex.org/W2009389738","https://openalex.org/W2014207233","https://openalex.org/W2014634548","https://openalex.org/W2040387898","https://openalex.org/W2055075605","https://openalex.org/W2058437162","https://openalex.org/W2065576581","https://openalex.org/W2075439429","https://openalex.org/W2088163075","https://openalex.org/W2091695712","https://openalex.org/W2094934579","https://openalex.org/W2095255852","https://openalex.org/W2098541552","https://openalex.org/W2109372372","https://openalex.org/W2118404859","https://openalex.org/W2167810526","https://openalex.org/W2230702682","https://openalex.org/W2259812842","https://openalex.org/W2285356324","https://openalex.org/W2307328122","https://openalex.org/W2460779416","https://openalex.org/W2474320362","https://openalex.org/W2519801595","https://openalex.org/W2529054276","https://openalex.org/W2559646480","https://openalex.org/W2586334726","https://openalex.org/W2771670907","https://openalex.org/W2799711263","https://openalex.org/W2885594994","https://openalex.org/W2896815534","https://openalex.org/W2900132127","https://openalex.org/W2900280452","https://openalex.org/W2902437774","https://openalex.org/W2903993408","https://openalex.org/W2915302538","https://openalex.org/W2916611451","https://openalex.org/W2929722513","https://openalex.org/W2936893058","https://openalex.org/W2972737609","https://openalex.org/W2993666578","https://openalex.org/W2994304950","https://openalex.org/W2996903540","https://openalex.org/W3021141903","https://openalex.org/W3033106668","https://openalex.org/W3041179120","https://openalex.org/W3083442625","https://openalex.org/W3083608872","https://openalex.org/W3087279172","https://openalex.org/W3093977038","https://openalex.org/W3106779259","https://openalex.org/W3116958217","https://openalex.org/W3125495858","https://openalex.org/W3158896465","https://openalex.org/W3195563535","https://openalex.org/W3196463755","https://openalex.org/W3215391682","https://openalex.org/W4205883985","https://openalex.org/W4213365409","https://openalex.org/W4213423463","https://openalex.org/W4223930092","https://openalex.org/W4225305784","https://openalex.org/W4246837663","https://openalex.org/W4280566962","https://openalex.org/W4280596605","https://openalex.org/W4282937282","https://openalex.org/W4282946930","https://openalex.org/W4283067838","https://openalex.org/W4289450217","https://openalex.org/W4292018635","https://openalex.org/W4319339586","https://openalex.org/W4322491975","https://openalex.org/W4322774989","https://openalex.org/W4383481674","https://openalex.org/W4385294677","https://openalex.org/W4385514610","https://openalex.org/W4386607910","https://openalex.org/W4386849526","https://openalex.org/W4386944634","https://openalex.org/W4387143075","https://openalex.org/W4387563050","https://openalex.org/W4388421122","https://openalex.org/W4388634881","https://openalex.org/W4389230430","https://openalex.org/W4392977196","https://openalex.org/W4399394849","https://openalex.org/W4399672192","https://openalex.org/W4400224893","https://openalex.org/W4400317561","https://openalex.org/W4402868174","https://openalex.org/W4403648166","https://openalex.org/W4403974261","https://openalex.org/W4404474208","https://openalex.org/W4405746371","https://openalex.org/W4406204082","https://openalex.org/W4408492440","https://openalex.org/W4409309664","https://openalex.org/W4410988936","https://openalex.org/W4412984599","https://openalex.org/W4413721575","https://openalex.org/W4417004581","https://openalex.org/W4417156810","https://openalex.org/W7151814623"],"related_works":["https://openalex.org/W3146051238","https://openalex.org/W2294789369","https://openalex.org/W7081923806","https://openalex.org/W4405746371","https://openalex.org/W2443531453","https://openalex.org/W2396561093","https://openalex.org/W4229794500","https://openalex.org/W4206666255","https://openalex.org/W4299649339","https://openalex.org/W4322491975"],"abstract_inverted_index":{"The":[0,165],"third":[1],"McMaster":[2],"Immune":[3],"Thrombocytopenia":[4],"(ITP)":[5],"Summit":[6],"was":[7],"held":[8],"on":[9,15,211],"7":[10],"November":[11],"2025":[12],"and":[13,20,39,43,45,53,80,129,153,161,176,178,202,205],"focused":[14],"comparing":[16],"the":[17,36,96,106,122,169,179,212],"mechanisms,":[18,58],"diagnoses,":[19],"treatments":[21],"with":[22,127,140,174],"warm":[23],"autoimmune":[24],"hemolytic":[25],"anemia":[26],"(wAIHA)":[27],"to":[28,73,133],"inform":[29],"our":[30],"understanding":[31],"of":[32,125,172,181,198],"ITP.":[33,141],"Topics":[34],"compared":[35,139],"clinical":[37],"presentation":[38],"laboratory":[40],"diagnosis,":[41],"pathophysiology,":[42],"current":[44],"emerging":[46],"therapies.":[47],"Key":[48],"messages":[49],"were":[50],"that":[51],"ITP":[52,90,109,177,199],"wAIHA":[54,101,138,175],"share":[55],"similar":[56],"immune":[57,82,155],"including":[59],"pathogenic":[60],"autoantibodies":[61],"against":[62],"platelets":[63],"or":[64,75],"red":[65],"blood":[66],"cells":[67],"(RBCs),":[68],"immune-mediated":[69],"cellular":[70],"pathways":[71,156],"leading":[72],"platelet":[74],"RBC":[76,116],"clearance,":[77],"complement":[78],"activation,":[79],"broader":[81],"dysregulation.":[83],"However,":[84],"there":[85],"are":[86],"several":[87],"distinct":[88],"differences:":[89],"is":[91,98,110],"more":[92,135],"common":[93],"than":[94],"wAIHA;":[95,128],"spleen":[97],"enlarged":[99],"in":[100,108,121,137],"but":[102],"not":[103,111],"primary":[104],"ITP;":[105],"autoantibody":[107,117],"readily":[112],"detectable,":[113],"whereas":[114],"an":[115],"can":[118],"be":[119,134],"found":[120],"vast":[123],"majority":[124],"patients":[126],"anti-CD20":[130],"therapy":[131],"appears":[132],"effective":[136],"Emerging":[142],"therapies":[143],"targeting":[144],"B-cell":[145],"signaling,":[146],"plasma":[147],"cells,":[148],"neonatal":[149],"Fc":[150],"receptor,":[151],"complement,":[152],"other":[154],"will":[157],"expand":[158],"treatment":[159,203,208],"options":[160],"clarify":[162],"disease":[163,200,214],"biology.":[164],"summit":[166],"also":[167],"highlighted":[168],"patient":[170,183],"experience":[171,184],"living":[173],"importance":[180],"incorporating":[182],"into":[185],"therapeutic":[186],"decision-making.":[187],"Future":[188],"priorities":[189],"include":[190],"improving":[191],"diagnostic":[192],"algorithms":[193],"for":[194],"ITP,":[195],"identifying":[196],"biomarkers":[197],"activity":[201],"response,":[204],"developing":[206],"individualized":[207],"strategies":[209],"based":[210],"underlying":[213],"mechanism.":[215]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-09-15T00:00:00"}
