{"id":"https://openalex.org/W7212428641","doi":"https://doi.org/10.3348/kjr.2026.0458","title":"Transarterial Radioembolization Versus Chemoembolization for Unresectable Large Single Hepatocellular Carcinoma","display_name":"Transarterial Radioembolization Versus Chemoembolization for Unresectable Large Single Hepatocellular Carcinoma","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7212428641","doi":"https://doi.org/10.3348/kjr.2026.0458","pmid":"https://pubmed.ncbi.nlm.nih.gov/42849888","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13655310"},"language":"en","primary_location":{"id":"doi:10.3348/kjr.2026.0458","doi":"https://doi.org/10.3348/kjr.2026.0458","is_oa":true,"landing_page_url":"https://doi.org/10.3348/kjr.2026.0458","pdf_url":"http://kjronline.org/Synapse/Data/PDFData/0068KJR/kjr-27-e93.pdf","source":{"id":"https://openalex.org/S75759149","display_name":"Korean Journal of Radiology","issn_l":"1229-6929","issn":["1229-6929","2005-8330"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","kci-registered","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319430","host_organization_name":"Korean Society of Radiology","host_organization_lineage":["https://openalex.org/P4310319430"],"host_organization_lineage_names":["Korean Society of Radiology"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Korean Journal of Radiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://kjronline.org/Synapse/Data/PDFData/0068KJR/kjr-27-e93.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003990838","display_name":"Myungsu Lee","orcid":"https://orcid.org/0000-0002-8320-5479","observed_orcids":["https://orcid.org/0000-0002-8320-5479"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]},{"id":"https://openalex.org/I2802835388","display_name":"Seoul National University Hospital","ror":"https://ror.org/01z4nnt86","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I139264467","https://openalex.org/I2802835388"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Myungsu Lee","raw_affiliation_strings":["Department of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-8320-5479","affiliations":[{"raw_affiliation_string":"Department of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467","https://openalex.org/I2802835388"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081550921","display_name":"Min Uk Kim","orcid":"https://orcid.org/0000-0003-0564-5724","observed_orcids":["https://orcid.org/0000-0003-0564-5724"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]},{"id":"https://openalex.org/I2802835388","display_name":"Seoul National University Hospital","ror":"https://ror.org/01z4nnt86","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I139264467","https://openalex.org/I2802835388"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Minuk Kim","raw_affiliation_strings":["Department of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0003-0564-5724","affiliations":[{"raw_affiliation_string":"Department of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467","https://openalex.org/I2802835388"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060389797","display_name":"Jayoun Kim","orcid":"https://orcid.org/0000-0003-2234-7091","observed_orcids":["https://orcid.org/0000-0003-2234-7091"]},"institutions":[{"id":"https://openalex.org/I2802835388","display_name":"Seoul National University Hospital","ror":"https://ror.org/01z4nnt86","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I139264467","https://openalex.org/I2802835388"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jayoun Kim","raw_affiliation_strings":["Medical Research Collaborating Center, Seoul National University Hospital, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0003-2234-7091","affiliations":[{"raw_affiliation_string":"Medical Research Collaborating Center, Seoul National University Hospital, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I2802835388"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100761874","display_name":"Do Hoon Kim","orcid":"https://orcid.org/0009-0007-7162-2586","observed_orcids":["https://orcid.org/0009-0007-7162-2586"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]},{"id":"https://openalex.org/I2802835388","display_name":"Seoul National University Hospital","ror":"https://ror.org/01z4nnt86","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I139264467","https://openalex.org/I2802835388"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Do Hoon Kim","raw_affiliation_strings":["Department of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea","Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0009-0007-7162-2586","affiliations":[{"raw_affiliation_string":"Department of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467","https://openalex.org/I2802835388"]},{"raw_affiliation_string":"Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007381775","display_name":"Jin Wook Chung","orcid":"https://orcid.org/0000-0002-1090-6872","observed_orcids":["https://orcid.org/0000-0002-1090-6872"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]},{"id":"https://openalex.org/I2802835388","display_name":"Seoul National University Hospital","ror":"https://ror.org/01z4nnt86","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I139264467","https://openalex.org/I2802835388"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jin Wook Chung","raw_affiliation_strings":["Department of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-1090-6872","affiliations":[{"raw_affiliation_string":"Department of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467","https://openalex.org/I2802835388"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059193103","display_name":"Hyo\u2010Cheol Kim","orcid":"https://orcid.org/0000-0002-6016-247X","observed_orcids":["https://orcid.org/0000-0002-6016-247X"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]},{"id":"https://openalex.org/I2802835388","display_name":"Seoul National University Hospital","ror":"https://ror.org/01z4nnt86","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I139264467","https://openalex.org/I2802835388"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Hyo-Cheol Kim","raw_affiliation_strings":["Department of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea","Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-6016-247X","affiliations":[{"raw_affiliation_string":"Department of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467","https://openalex.org/I2802835388"]},{"raw_affiliation_string":"Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5059193103"],"corresponding_institution_ids":["https://openalex.org/I139264467","https://openalex.org/I2802835388"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.67474829,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"27","issue":"10","first_page":"961","last_page":"961"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.8799999952316284},{"id":"https://openalex.org/keywords/radioembolization","display_name":"radioembolization","score":0.949999988079071},{"id":"https://openalex.org/keywords/transarterial-chemoembolization","display_name":"transarterial chemoembolization","score":0.9539999961853027},{"id":"https://openalex.org/keywords/unresectable-liver-cancer","display_name":"unresectable liver cancer","score":0.7699999809265137},{"id":"https://openalex.org/keywords/lung-shunt-fraction","display_name":"lung shunt fraction","score":0.8619999885559082},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9369999766349792},{"id":"https://openalex.org/keywords/local-progression-free-survival","display_name":"local progression-free survival","score":0.8519999980926514},{"id":"https://openalex.org/keywords/treatment-safety","display_name":"treatment safety","score":0.6029999852180481},{"id":"https://openalex.org/keywords/adverse-events","display_name":"adverse events","score":0.8330000042915344},{"id":"https://openalex.org/keywords/length-of-hospital-stay","display_name":"length of hospital stay","score":0.4309999942779541},{"id":"https://openalex.org/keywords/yttrium-90-microspheres","display_name":"yttrium-90 microspheres","score":0.718999981880188},{"id":"https://openalex.org/keywords/liver-reserve-function","display_name":"liver function reserve","score":0.30300000309944153}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9842000007629395},{"id":"https://openalex.org/C2778019345","wikidata":"https://www.wikidata.org/wiki/Q1148337","display_name":"Hepatocellular carcinoma","level":2,"score":0.7404000163078308},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.7211999893188477},{"id":"https://openalex.org/C2778455285","wikidata":"https://www.wikidata.org/wiki/Q221788","display_name":"Transcatheter arterial chemoembolization","level":3,"score":0.32010000944137573},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.31189998984336853},{"id":"https://openalex.org/C2909913126","wikidata":"https://www.wikidata.org/wiki/Q221788","display_name":"Transarterial embolization","level":3,"score":0.30399999022483826},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.30309998989105225},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.3012000024318695},{"id":"https://openalex.org/C544519230","wikidata":"https://www.wikidata.org/wiki/Q32566","display_name":"Computed tomography","level":2,"score":0.27869999408721924},{"id":"https://openalex.org/C2776035437","wikidata":"https://www.wikidata.org/wiki/Q1144114","display_name":"Embolization","level":2,"score":0.24819999933242798}],"mesh":[{"descriptor_ui":"D000099142","descriptor_name":"Radioembolization, Therapeutic","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006528","descriptor_name":"Carcinoma, Hepatocellular","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D006528","descriptor_name":"Carcinoma, Hepatocellular","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006528","descriptor_name":"Carcinoma, Hepatocellular","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015021","descriptor_name":"Yttrium Radioisotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016461","descriptor_name":"Chemoembolization, Therapeutic","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3348/kjr.2026.0458","doi":"https://doi.org/10.3348/kjr.2026.0458","is_oa":true,"landing_page_url":"https://doi.org/10.3348/kjr.2026.0458","pdf_url":"http://kjronline.org/Synapse/Data/PDFData/0068KJR/kjr-27-e93.pdf","source":{"id":"https://openalex.org/S75759149","display_name":"Korean Journal of Radiology","issn_l":"1229-6929","issn":["1229-6929","2005-8330"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","kci-registered","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319430","host_organization_name":"Korean Society of Radiology","host_organization_lineage":["https://openalex.org/P4310319430"],"host_organization_lineage_names":["Korean Society of Radiology"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Korean Journal of Radiology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13655310","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13655310/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13655310/pdf/kjr-27-961.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Korean J Radiol","raw_type":"Text"},{"id":"pmid:42849888","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42849888","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Korean journal of radiology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3348/kjr.2026.0458","doi":"https://doi.org/10.3348/kjr.2026.0458","is_oa":true,"landing_page_url":"https://doi.org/10.3348/kjr.2026.0458","pdf_url":"http://kjronline.org/Synapse/Data/PDFData/0068KJR/kjr-27-e93.pdf","source":{"id":"https://openalex.org/S75759149","display_name":"Korean Journal of Radiology","issn_l":"1229-6929","issn":["1229-6929","2005-8330"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","kci-registered","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319430","host_organization_name":"Korean Society of Radiology","host_organization_lineage":["https://openalex.org/P4310319430"],"host_organization_lineage_names":["Korean Society of Radiology"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Korean Journal of Radiology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7212428641.pdf","grobid_xml":"https://content.openalex.org/works/W7212428641.grobid-xml"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W1982200516","https://openalex.org/W2079586464","https://openalex.org/W2166937118","https://openalex.org/W2298508438","https://openalex.org/W2384304121","https://openalex.org/W2509930573","https://openalex.org/W2782635689","https://openalex.org/W2895042645","https://openalex.org/W4221122116","https://openalex.org/W4316362725","https://openalex.org/W4323320012","https://openalex.org/W4377011124","https://openalex.org/W4379537075","https://openalex.org/W4383312086","https://openalex.org/W4387849533","https://openalex.org/W4402842767","https://openalex.org/W4406545406","https://openalex.org/W4410856713","https://openalex.org/W4411192062","https://openalex.org/W4411705487","https://openalex.org/W4411734607","https://openalex.org/W4415016322","https://openalex.org/W4415559753"],"related_works":["https://openalex.org/W4295241246","https://openalex.org/W4387505713","https://openalex.org/W4402920852","https://openalex.org/W4200137637","https://openalex.org/W4241175378","https://openalex.org/W2591366170","https://openalex.org/W2898523929","https://openalex.org/W4386761434","https://openalex.org/W4406545406","https://openalex.org/W4412097150"],"abstract_inverted_index":{"Objective:":[0],"To":[1],"compare":[2],"oncologic":[3],"outcomes":[4,89],"and":[5,11,27,51,87,98,187,236,268],"safety":[6],"between":[7,48],"transarterial":[8,12],"radioembolization":[9],"(TARE)":[10],"chemoembolization":[13],"(TACE)":[14],"in":[15,77,112,122],"patients":[16,33,119,252],"with":[17,34,44,65,177,202,220,225,253,261,281],"unresectable":[18,254],"large":[19,255],"solitary":[20,36,256],"hepatocellular":[21],"carcinomas":[22],"(HCCs;":[23],"\u22656":[24,38],"cm).":[25],"Materials":[26],"Methods:This":[28],"single-center":[29],"retrospective":[30],"study":[31,124],"included":[32,76,90,121],"a":[35,69,237],"HCC":[37],"cm":[39],"who":[40,54,154],"underwent":[41],"initial":[42],"treatment":[43,102],"TARE":[45,60,136,158,174,203,222,258],"or":[46],"TACE":[47,66,79,144],"January":[49],"2010":[50],"December":[52],"2023.Patients":[53],"were":[55,62,75,120,155],"initially":[56],"scheduled":[57],"to":[58,107,287,293],"undergo":[59],"but":[61,208],"subsequently":[63],"treated":[64],"because":[67,159,283],"of":[68,101,160,241],"high":[70],"lung":[71,162],"shunt":[72],"fraction":[73],"(LSF)":[74],"the":[78,113,135,143,209,275,294],"group.The":[80],"primary":[81],"outcome":[82],"was":[83,105,223,259],"overall":[84],"survival":[85,92,114,167,276],"(OS),":[86],"secondary":[88],"progression-free":[91],"(PFS),":[93],"local":[94,188,265],"PFS,":[95],"tumor":[96,266],"response,":[97],"safety.Inverse":[99],"probability":[100],"weighting":[103],"(IPTW)":[104],"used":[106],"adjust":[108],"for":[109,157],"baseline":[110],"differences":[111],"analyses.Results:":[115],"In":[116],"total,":[117],"306":[118],"this":[123],"(TACE,":[125],"n":[126,130],"=":[127,131,152,185,196,217],"187;":[128],"TARE,":[129],"119).Before":[132],"IPTW":[133,172],"adjustment,":[134,173],"group":[137,145],"demonstrated":[138,164],"significantly":[139],"longer":[140,178,201,262],"OS":[141,179],"than":[142,273],"(median,":[146,180,190],"79.6":[147,181],"vs.":[148,182,192,205,232,247],"46.5":[149],"months;":[150,194],"P":[151,184,195],"0.004).Patients":[153],"ineligible":[156],"extensive":[161],"shunting":[163],"particularly":[165],"poor":[166],"(median":[168],"OS,":[169,263],"20.3":[170],"months).After":[171],"remained":[175,199],"associated":[176,224,260],"53.4months;":[183],"0.033)":[186],"PFS":[189,198],"25.1":[191],"9.5":[193],"0.001).Median":[197],"numerically":[200],"(9.8":[204],"7.8":[206],"months),":[207],"difference":[210],"did":[211],"not":[212],"reach":[213],"statistical":[214],"significance":[215],"(P":[216],"0.066).In":[218],"comparison":[219],"TACE,":[221],"less":[226],"frequent":[227],"serious":[228,270],"adverse":[229,271],"events":[230,272],"(10.1%":[231],"26.7%;P":[233],"<":[234,249],"0.01)":[235],"markedly":[238],"lower":[239],"rate":[240],"prolonged":[242],"hospitalization":[243],"(>7":[244],"days)":[245],"(0.8%":[246],"22.5%;P":[248],"0.01).":[250],"Conclusion:In":[251],"HCCs,":[257],"improved":[264],"control,":[267],"fewer":[269],"TACE.However,":[274],"advantage":[277],"should":[278],"be":[279],"interpreted":[280],"caution,":[282],"biological":[284],"selection":[285],"related":[286],"LSF":[288],"eligibility":[289],"may":[290],"have":[291],"contributed":[292],"observed":[295],"difference.":[296]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2026-09-14T00:00:00"}