{"id":"https://openalex.org/W7212379732","doi":"https://doi.org/10.64898/2026.09.09.26362696","title":"Body mass index and the duration of the pubertal growth spurt in Vietnamese urban children","display_name":"Body mass index and the duration of the pubertal growth spurt in Vietnamese urban children","publication_year":2026,"publication_date":"2026-09-11","ids":{"openalex":"https://openalex.org/W7212379732","doi":"https://doi.org/10.64898/2026.09.09.26362696"},"language":"en","primary_location":{"id":"doi:10.64898/2026.09.09.26362696","doi":"https://doi.org/10.64898/2026.09.09.26362696","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.09.26362696","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/11/2026.09.09.26362696.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/11/2026.09.09.26362696.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028872568","display_name":"Nhan Thi Ho","orcid":"https://orcid.org/0000-0002-7898-0956","observed_orcids":["https://orcid.org/0000-0002-7898-0956"]},"institutions":[{"id":"https://openalex.org/I4210109845","display_name":"Vinmec Times City International Hospital","ror":"https://ror.org/01q2pxs68","country_code":"VN","type":"healthcare","lineage":["https://openalex.org/I4210109845","https://openalex.org/I4387154326","https://openalex.org/I4405276989"]},{"id":"https://openalex.org/I4210142044","display_name":"VinUniversity","ror":"https://ror.org/052dmdr17","country_code":"VN","type":"education","lineage":["https://openalex.org/I4210142044"]}],"countries":["VN"],"is_corresponding":true,"raw_author_name":"Nhan T. Ho","raw_affiliation_strings":["College of Health Sciences, VinUniversity, Hanoi, Vietnam","Pediatric Department, Vinmec Times City International Hospital, Vinmec International Hospital, Hanoi, Vietnam","Research Management Department, Vinmec International Hospital, Hanoi, Vietnam"],"raw_orcid":"https://orcid.org/0000-0002-7898-0956","affiliations":[{"raw_affiliation_string":"College of Health Sciences, VinUniversity, Hanoi, Vietnam","institution_ids":["https://openalex.org/I4210142044"]},{"raw_affiliation_string":"Pediatric Department, Vinmec Times City International Hospital, Vinmec International Hospital, Hanoi, Vietnam","institution_ids":["https://openalex.org/I4210109845"]},{"raw_affiliation_string":"Research Management Department, Vinmec International Hospital, Hanoi, Vietnam","institution_ids":["https://openalex.org/I4210109845"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5028872568"],"corresponding_institution_ids":["https://openalex.org/I4210109845","https://openalex.org/I4210142044"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.9735999703407288,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.9735999703407288,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":0.011099999770522118,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13091","display_name":"Human Health and Disease","score":0.009100000374019146,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.9190000295639038},{"id":"https://openalex.org/keywords/pubertal-growth-spurt","display_name":"pubertal growth spurt","score":0.925000011920929},{"id":"https://openalex.org/keywords/childhood-obesity","display_name":"childhood obesity","score":0.6549999713897705},{"id":"https://openalex.org/keywords/peak-height-velocity","display_name":"peak height velocity","score":0.8119999766349792},{"id":"https://openalex.org/keywords/pubertal-timing","display_name":"pubertal timing","score":0.9369999766349792},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.6930000185966492},{"id":"https://openalex.org/keywords/full-width-at-half-maximum","display_name":"full width at half maximum","score":0.8569999933242798},{"id":"https://openalex.org/keywords/vietnamese-children","display_name":"Vietnamese children","score":0.5049999952316284}],"concepts":[{"id":"https://openalex.org/C68443243","wikidata":"https://www.wikidata.org/wiki/Q2786686","display_name":"Quartile","level":3,"score":0.8355000019073486},{"id":"https://openalex.org/C2994002724","wikidata":"https://www.wikidata.org/wiki/Q476112","display_name":"Growth spurt","level":2,"score":0.7117000222206116},{"id":"https://openalex.org/C112758219","wikidata":"https://www.wikidata.org/wiki/Q16038819","display_name":"Duration (music)","level":2,"score":0.7013000249862671},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.675599992275238},{"id":"https://openalex.org/C103621254","wikidata":"https://www.wikidata.org/wiki/Q9199","display_name":"Vietnamese","level":2,"score":0.6700999736785889},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.583299994468689},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5088000297546387},{"id":"https://openalex.org/C3017783442","wikidata":"https://www.wikidata.org/wiki/Q476112","display_name":"Body height","level":3,"score":0.424699991941452},{"id":"https://openalex.org/C2991696056","wikidata":"https://www.wikidata.org/wiki/Q2299582","display_name":"Growth velocity","level":2,"score":0.37130001187324524},{"id":"https://openalex.org/C61427482","wikidata":"https://www.wikidata.org/wiki/Q6656244","display_name":"Anthropometry","level":2,"score":0.3228999972343445},{"id":"https://openalex.org/C2776035688","wikidata":"https://www.wikidata.org/wiki/Q1606558","display_name":"Affect (linguistics)","level":2,"score":0.27390000224113464},{"id":"https://openalex.org/C61797465","wikidata":"https://www.wikidata.org/wiki/Q1188986","display_name":"Term (time)","level":2,"score":0.26910001039505005},{"id":"https://openalex.org/C2777382242","wikidata":"https://www.wikidata.org/wiki/Q6017816","display_name":"Index (typography)","level":2,"score":0.2676999866962433},{"id":"https://openalex.org/C179861144","wikidata":"https://www.wikidata.org/wiki/Q2168094","display_name":"Varimax rotation","level":4,"score":0.2646999955177307},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.25999999046325684},{"id":"https://openalex.org/C2779543058","wikidata":"https://www.wikidata.org/wiki/Q4200712","display_name":"Mass index","level":3,"score":0.25619998574256897},{"id":"https://openalex.org/C2778945730","wikidata":"https://www.wikidata.org/wiki/Q1517875","display_name":"Sex characteristics","level":2,"score":0.2526000142097473}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.09.09.26362696","doi":"https://doi.org/10.64898/2026.09.09.26362696","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.09.26362696","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/11/2026.09.09.26362696.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.64898/2026.09.09.26362696","doi":"https://doi.org/10.64898/2026.09.09.26362696","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.09.26362696","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/09/11/2026.09.09.26362696.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7212379732.pdf","grobid_xml":"https://content.openalex.org/works/W7212379732.grobid-xml"},"referenced_works_count":5,"referenced_works":["https://openalex.org/W1995945562","https://openalex.org/W4399637561","https://openalex.org/W4410226163","https://openalex.org/W7171648573","https://openalex.org/W7171725742"],"related_works":["https://openalex.org/W7211947849","https://openalex.org/W7171648573","https://openalex.org/W2361754005","https://openalex.org/W4408755490","https://openalex.org/W7171725742","https://openalex.org/W2896420101","https://openalex.org/W7135233456","https://openalex.org/W3130206120","https://openalex.org/W7166844280","https://openalex.org/W2009153241"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Higher":[2,143],"childhood":[3],"body":[4],"mass":[5],"index":[6],"(BMI)":[7],"is":[8,26],"linked":[9],"to":[10,155,218],"earlier":[11],"and":[12,32,43,51,81,88,97,103,120,139,176,225],"less":[13],"intense":[14],"pubertal":[15,101],"growth":[16,46,85,171,214],"spurts,":[17],"but":[18,115,166],"whether":[19],"it":[20],"also":[21],"changes":[22],"the":[23,163],"spurt":[24,215],"duration":[25,65,132,148,173,216,233],"rarely":[27],"studied,":[28],"especially":[29],"in":[30,54,111,149,161,248],"Vietnam":[31],"Southeast":[33],"Asia.":[34],"Methods":[35],"We":[36],"used":[37],"previously":[38],"fitted":[39],"Superimposition":[40],"by":[41,193,221],"Translation":[42],"Rotation":[44],"(SITAR)":[45],"curves":[47],"for":[48,100,135],"8,018":[49],"boys":[50,114,138],"5,491":[52],"girls":[53,122],"a":[55,73,82,190],"multicity":[56],"Vietnamese":[57],"cohort.":[58],"For":[59],"each":[60,239],"child":[61],"we":[62],"derived":[63],"two":[64],"measures":[66,234],"from":[67],"their":[68],"own":[69,241],"predicted":[70,145],"velocity":[71],"curve,":[72],"full":[74],"width":[75,231],"at":[76],"half":[77],"maximum":[78],"(FWHM)":[79],"measure":[80],"threshold":[83],"free":[84],"quartile":[86,131,172],"duration,":[87],"tested":[89],"associations":[90],"with":[91,189],"prepubertal":[92],"BMI":[93,144,183,192,219],"z":[94,184],"score":[95],"before":[96,245],"after":[98],"adjusting":[99],"timing":[102,224],"peak":[104],"height":[105],"velocity.":[106],"Results":[107],"FWHM":[108],"was":[109,133],"identifiable":[110,121],"99.9%":[112],"of":[113,118,141,207],"only":[116],"18.0%":[117],"girls,":[119,170],"had":[123],"systematically":[124],"lower":[125],"BMI,":[126],"indicating":[127],"informative":[128],"missingness.":[129],"Growth":[130],"available":[134,242],"nearly":[136],"all":[137],"94.9%":[140],"girls.":[142,249],"shorter":[146],"unadjusted":[147],"both":[150],"sexes":[151],"(p":[152,196],"<":[153],"0.001":[154],"p":[156,186],"=":[157,187,197],"0.037).":[158],"After":[159],"adjustment,":[160],"boys,":[162],"association":[164],"weakened":[165],"stayed":[167],"significant.":[168],"In":[169],"reversed":[174],"direction":[175],"remained":[177],"significant":[178,191],"(0.0052":[179],"years":[180],"per":[181],"unit":[182],"score,":[185],"0.004),":[188],"sex":[194,222],"interaction":[195],"0.007).":[198],"Functional":[199],"principal":[200],"component":[201],"analysis":[202],"confirmed":[203],"these":[204],"findings":[205],"independent":[206],"any":[208],"single":[209],"model":[210],"parameter.":[211],"Conclusion":[212],"Pubertal":[213],"responds":[217],"differently":[220],"once":[223],"intensity":[226],"are":[227],"accounted":[228],"for.":[229],"Full":[230],"based":[232],"should":[235],"be":[236],"checked":[237],"against":[238],"child\u2019s":[240],"age":[243],"range":[244],"use,":[246],"particularly":[247]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-09-13T00:00:00"}