{"id":"https://openalex.org/W7212372546","doi":"https://doi.org/10.15446/rcciquifa.v55n3.129593","title":"Antiophidic potential of plants used in traditional medicine in the municipality of Dolores (Tolima), Colombia","display_name":"Antiophidic potential of plants used in traditional medicine in the municipality of Dolores (Tolima), Colombia","publication_year":2026,"publication_date":"2026-09-11","ids":{"openalex":"https://openalex.org/W7212372546","doi":"https://doi.org/10.15446/rcciquifa.v55n3.129593"},"language":"en","primary_location":{"id":"doi:10.15446/rcciquifa.v55n3.129593","doi":"https://doi.org/10.15446/rcciquifa.v55n3.129593","is_oa":true,"landing_page_url":"https://doi.org/10.15446/rcciquifa.v55n3.129593","pdf_url":"https://revistas.unal.edu.co/index.php/rccquifa/article/download/129593/99430","source":{"id":"https://openalex.org/S4210177770","display_name":"Revista Colombiana de Ciencias Qu\u00edmico Farmac\u00e9uticas","issn_l":"0034-7418","issn":["0034-7418","1909-6356"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","publindex-c","russia-white-list-4"],"host_organization":"https://openalex.org/P4310318911","host_organization_name":"National University of Colombia","host_organization_lineage":["https://openalex.org/P4310318911"],"host_organization_lineage_names":["National University of Colombia"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Colombiana de Ciencias Qu\u00edmico-Farmac\u00e9uticas","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W7212372546"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://revistas.unal.edu.co/index.php/rccquifa/article/download/129593/99430","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5117716083","display_name":"Sanin Parra-Moreno","orcid":"https://orcid.org/0009-0003-9028-750X","observed_orcids":["https://orcid.org/0009-0003-9028-750X"]},"institutions":[{"id":"https://openalex.org/I31703152","display_name":"Universidad del Tolima","ror":"https://ror.org/011bqgx84","country_code":"CO","type":"education","lineage":["https://openalex.org/I31703152"]}],"countries":["CO"],"is_corresponding":false,"raw_author_name":"Sanin Parra-Moreno","raw_affiliation_strings":["Programa de Biolog\u00eda, Universidad del Tolima, Ibagu\u00e9, Colombia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programa de Biolog\u00eda, Universidad del Tolima, Ibagu\u00e9, Colombia","institution_ids":["https://openalex.org/I31703152"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5151480013","display_name":"Karol Ardila-Cubillos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I31703152","display_name":"Universidad del Tolima","ror":"https://ror.org/011bqgx84","country_code":"CO","type":"education","lineage":["https://openalex.org/I31703152"]}],"countries":["CO"],"is_corresponding":false,"raw_author_name":"Karol Ardila-Cubillos","raw_affiliation_strings":["Programa de Biolog\u00eda, Universidad del Tolima, Ibagu\u00e9, Colombia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programa de Biolog\u00eda, Universidad del Tolima, Ibagu\u00e9, Colombia","institution_ids":["https://openalex.org/I31703152"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5132786153","display_name":"Edwar Cortes-Gonzalez","orcid":"https://orcid.org/0000-0002-2302-0931","observed_orcids":["https://orcid.org/0000-0002-2302-0931"]},"institutions":[{"id":"https://openalex.org/I31703152","display_name":"Universidad del Tolima","ror":"https://ror.org/011bqgx84","country_code":"CO","type":"education","lineage":["https://openalex.org/I31703152"]}],"countries":["CO"],"is_corresponding":false,"raw_author_name":"Edwar Cort\u00e9s","raw_affiliation_strings":["Grupo de Investigaci\u00f3n en Productos Naturales, Universidad del Tolima, Ibagu\u00e9, Colombia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grupo de Investigaci\u00f3n en Productos Naturales, Universidad del Tolima, Ibagu\u00e9, Colombia","institution_ids":["https://openalex.org/I31703152"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084781154","display_name":"W. Murillo-Arango","orcid":"https://orcid.org/0000-0002-1482-070X","observed_orcids":["https://orcid.org/0000-0002-1482-070X"]},"institutions":[{"id":"https://openalex.org/I31703152","display_name":"Universidad del Tolima","ror":"https://ror.org/011bqgx84","country_code":"CO","type":"education","lineage":["https://openalex.org/I31703152"]}],"countries":["CO"],"is_corresponding":false,"raw_author_name":"Walter Murillo-Arango","raw_affiliation_strings":["Grupo de Investigaci\u00f3n en Productos Naturales, Universidad del Tolima, Ibagu\u00e9, Colombia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grupo de Investigaci\u00f3n en Productos Naturales, Universidad del Tolima, Ibagu\u00e9, Colombia","institution_ids":["https://openalex.org/I31703152"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5151465478","display_name":"Arturo Romero-Barrera","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I31703152","display_name":"Universidad del Tolima","ror":"https://ror.org/011bqgx84","country_code":"CO","type":"education","lineage":["https://openalex.org/I31703152"]}],"countries":["CO"],"is_corresponding":false,"raw_author_name":"Arturo Romero-Barrera","raw_affiliation_strings":["Programa de Biolog\u00eda, Universidad del Tolima, Ibagu\u00e9, Colombia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Programa de Biolog\u00eda, Universidad del Tolima, Ibagu\u00e9, Colombia","institution_ids":["https://openalex.org/I31703152"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069808464","display_name":"Paola Rey-Su\u00e1rez","orcid":"https://orcid.org/0000-0003-3299-2246","observed_orcids":["https://orcid.org/0000-0003-3299-2246"]},"institutions":[{"id":"https://openalex.org/I35961687","display_name":"Universidad de Antioquia","ror":"https://ror.org/03bp5hc83","country_code":"CO","type":"education","lineage":["https://openalex.org/I35961687"]}],"countries":["CO"],"is_corresponding":false,"raw_author_name":"Paola Rey-Su\u00e1rez","raw_affiliation_strings":["Grupo de Investigaci\u00f3n en Toxinolog\u00eda, Alternativas Terap\u00e9uticas y Alimentarias, Universidad de Antioquia, Medell\u00edn, Colombia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grupo de Investigaci\u00f3n en Toxinolog\u00eda, Alternativas Terap\u00e9uticas y Alimentarias, Universidad de Antioquia, Medell\u00edn, Colombia","institution_ids":["https://openalex.org/I35961687"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"55","issue":"3","first_page":"1071","last_page":"1087"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11353","display_name":"Venomous Animal Envenomation and Studies","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11353","display_name":"Venomous Animal Envenomation and Studies","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10431","display_name":"Ethnobotanical and Medicinal Plants Studies","score":0.007699999958276749,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12657","display_name":"Phytochemistry Medicinal Plant Applications","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/snakebite","display_name":"snakebite","score":0.9620000123977661},{"id":"https://openalex.org/keywords/bothrops-asper","display_name":"Bothrops asper","score":0.9350000023841858},{"id":"https://openalex.org/keywords/traditional-medicine","display_name":"traditional medicine","score":0.8740000128746033},{"id":"https://openalex.org/keywords/ethnobotany","display_name":"ethnobotany","score":0.8100000023841858},{"id":"https://openalex.org/keywords/plant-extracts","display_name":"plant extracts","score":0.6629999876022339},{"id":"https://openalex.org/keywords/proteolytic-activity-inhibition","display_name":"proteolytic activity inhibition","score":0.7599999904632568},{"id":"https://openalex.org/keywords/hemolytic-activity","display_name":"hemolytic activity","score":0.8349999785423279},{"id":"https://openalex.org/keywords/cassava","display_name":"cassava","score":0.9589999914169312},{"id":"https://openalex.org/keywords/senna-reticulata","display_name":"Senna reticulata","score":0.9860000014305115},{"id":"https://openalex.org/keywords/sugarcane","display_name":"sugarcane","score":0.9240000247955322},{"id":"https://openalex.org/keywords/bidens-pilosa","display_name":"Bidens pilosa","score":0.9819999933242798},{"id":"https://openalex.org/keywords/traditional-healers","display_name":"traditional healers","score":0.7260000109672546}],"concepts":[{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.6531999707221985},{"id":"https://openalex.org/C2779158651","wikidata":"https://www.wikidata.org/wiki/Q188840","display_name":"Medicinal plants","level":2,"score":0.5026000142097473},{"id":"https://openalex.org/C202216756","wikidata":"https://www.wikidata.org/wiki/Q841408","display_name":"Ethnobotany","level":3,"score":0.4302999973297119},{"id":"https://openalex.org/C2781380062","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Folk medicine","level":2,"score":0.3763999938964844},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3562999963760376},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.34630000591278076},{"id":"https://openalex.org/C2781445593","wikidata":"https://www.wikidata.org/wiki/Q149056","display_name":"Manihot","level":2,"score":0.34049999713897705},{"id":"https://openalex.org/C145600735","wikidata":"https://www.wikidata.org/wiki/Q3055418","display_name":"Envenomation","level":3,"score":0.32409998774528503},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3192000091075897},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.30559998750686646},{"id":"https://openalex.org/C42972112","wikidata":"https://www.wikidata.org/wiki/Q170201","display_name":"Veterinary medicine","level":1,"score":0.301800012588501},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.28360000252723694},{"id":"https://openalex.org/C33070731","wikidata":"https://www.wikidata.org/wiki/Q7218","display_name":"Toxicology","level":1,"score":0.2750999927520752},{"id":"https://openalex.org/C514011633","wikidata":"https://www.wikidata.org/wiki/Q1428168","display_name":"Traditional knowledge","level":3,"score":0.26350000500679016},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.2612999975681305},{"id":"https://openalex.org/C2776295790","wikidata":"https://www.wikidata.org/wiki/Q967457","display_name":"Poppy","level":2,"score":0.25279998779296875}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.15446/rcciquifa.v55n3.129593","doi":"https://doi.org/10.15446/rcciquifa.v55n3.129593","is_oa":true,"landing_page_url":"https://doi.org/10.15446/rcciquifa.v55n3.129593","pdf_url":"https://revistas.unal.edu.co/index.php/rccquifa/article/download/129593/99430","source":{"id":"https://openalex.org/S4210177770","display_name":"Revista Colombiana de Ciencias Qu\u00edmico Farmac\u00e9uticas","issn_l":"0034-7418","issn":["0034-7418","1909-6356"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","publindex-c","russia-white-list-4"],"host_organization":"https://openalex.org/P4310318911","host_organization_name":"National University of Colombia","host_organization_lineage":["https://openalex.org/P4310318911"],"host_organization_lineage_names":["National University of Colombia"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Colombiana de Ciencias Qu\u00edmico-Farmac\u00e9uticas","raw_type":"journal-article"},{"id":"pmh:oai:ojs.unal.edu.co:article/129593","doi":null,"is_oa":true,"landing_page_url":"https://revistas.unal.edu.co/index.php/rccquifa/article/view/129593","pdf_url":null,"source":{"id":"https://openalex.org/S4210177770","display_name":"Revista Colombiana de Ciencias Qu\u00edmico Farmac\u00e9uticas","issn_l":"0034-7418","issn":["0034-7418","1909-6356"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","publindex-c","russia-white-list-4"],"host_organization":"https://openalex.org/P4310318911","host_organization_name":"National University of Colombia","host_organization_lineage":["https://openalex.org/P4310318911"],"host_organization_lineage_names":["National University of Colombia"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"0034-7418","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.15446/rcciquifa.v55n3.129593","doi":"https://doi.org/10.15446/rcciquifa.v55n3.129593","is_oa":true,"landing_page_url":"https://doi.org/10.15446/rcciquifa.v55n3.129593","pdf_url":"https://revistas.unal.edu.co/index.php/rccquifa/article/download/129593/99430","source":{"id":"https://openalex.org/S4210177770","display_name":"Revista Colombiana de Ciencias Qu\u00edmico Farmac\u00e9uticas","issn_l":"0034-7418","issn":["0034-7418","1909-6356"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","publindex-c","russia-white-list-4"],"host_organization":"https://openalex.org/P4310318911","host_organization_name":"National University of Colombia","host_organization_lineage":["https://openalex.org/P4310318911"],"host_organization_lineage_names":["National University of Colombia"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Colombiana de Ciencias Qu\u00edmico-Farmac\u00e9uticas","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320318904","display_name":"Universidad del Tolima","ror":"https://ror.org/011bqgx84"},{"id":"https://openalex.org/F4320323197","display_name":"Universidad de Antioquia","ror":"https://ror.org/03bp5hc83"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7212372546.pdf","grobid_xml":"https://content.openalex.org/works/W7212372546.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W193839339","https://openalex.org/W194340916","https://openalex.org/W326119199","https://openalex.org/W1608359000","https://openalex.org/W1809748874","https://openalex.org/W1964256253","https://openalex.org/W1976658337","https://openalex.org/W1981325790","https://openalex.org/W1994332990","https://openalex.org/W1996412693","https://openalex.org/W2012977074","https://openalex.org/W2022313892","https://openalex.org/W2032713792","https://openalex.org/W2037439512","https://openalex.org/W2050080364","https://openalex.org/W2056260847","https://openalex.org/W2073648663","https://openalex.org/W2074628782","https://openalex.org/W2076724770","https://openalex.org/W2088417031","https://openalex.org/W2100837269","https://openalex.org/W2108172578","https://openalex.org/W2112883612","https://openalex.org/W2115761168","https://openalex.org/W2139051050","https://openalex.org/W2307799631","https://openalex.org/W2342116162","https://openalex.org/W2514893687","https://openalex.org/W2748744584","https://openalex.org/W2783129775","https://openalex.org/W2795432924","https://openalex.org/W2946622764","https://openalex.org/W3007982338","https://openalex.org/W3093339293","https://openalex.org/W3157746620","https://openalex.org/W3162259718","https://openalex.org/W4285094931","https://openalex.org/W4285803757","https://openalex.org/W4292247168","https://openalex.org/W4382140496"],"related_works":["https://openalex.org/W326119199","https://openalex.org/W3201769480","https://openalex.org/W2076724770","https://openalex.org/W194340916","https://openalex.org/W3168688564","https://openalex.org/W1638458789","https://openalex.org/W1480932952","https://openalex.org/W7207290620","https://openalex.org/W1809748874","https://openalex.org/W4398211262"],"abstract_inverted_index":{"Introduction:":[0],"In":[1],"Colombia,":[2],"the":[3,28,35,58,69,79,119,124,157,162,174,191,224,237,245,255,261,267,270],"incidence":[4],"of":[5,23,30,61,72,81,131,170,176,231,247,251,273],"snakebite":[6,41],"accidents":[7],"is":[8,27,43],"high":[9,21],"due":[10],"to":[11,55,67,236],"its":[12,20],"sociodemographic":[13],"and":[14,111,128,151,183,201,204,213,264],"environmental":[15],"characteristics,":[16],"as":[17,19,83],"well":[18],"diversity":[22],"snakes.":[24],"Bothrops":[25],"asper":[26,133],"species":[29,142],"greatest":[31],"clinical":[32],"importance":[33],"in":[34,75,78,223,244,260],"country.":[36],"The":[37,103,141,165,229,249],"current":[38],"treatment":[39,47,85,246],"for":[40,86,239,266],"envenomation":[42],"antivenom;":[44],"however,":[45],"this":[46,252],"has":[48],"some":[49],"limitations":[50],"that":[51],"have":[52],"led":[53],"communities":[54],"rely":[56],"on":[57,123],"traditional":[59,76,101,163],"use":[60,233],"plants.":[62],"Purpose:":[63],"This":[64],"study":[65,166,253,259],"aimed":[66],"evaluate":[68],"antiophidic":[70,258,271],"potential":[71,272],"plants":[73,108,159],"used":[74],"medicine":[77],"municipality":[80],"Dolores-Tolima":[82],"a":[84],"symptoms":[87],"associated":[88],"with":[89,99],"snakebites.":[90,248],"Methodology:":[91],"To":[92],"do":[93],"this,":[94],"semi-structured":[95],"surveys":[96],"were":[97,109,114,135,154],"conducted":[98],"local":[100],"healers.":[102,164],"five":[104],"most":[105],"frequently":[106],"mentioned":[107],"selected,":[110],"ethanolic":[112],"extracts":[113,175],"prepared":[115],"from":[116,156],"them.":[117],"Subsequently,":[118],"extracts'":[120],"inhibitory":[121],"capacity":[122],"indirect":[125,205],"hemolytic,":[126],"proteolytic,":[127],"coagulant":[129,186],"activities":[130],"B.":[132],"venom":[134],"evaluated":[136],"through":[137],"in-vitro":[138],"assays.":[139],"Results:":[140],"Manihot":[143],"esculenta,":[144,182,200],"Pseudelephantopus":[145],"spiralis,":[146,180,196],"Senna":[147],"reticulata,":[148,178,198],"Saccharum":[149],"officinarum,":[150],"Bidens":[152],"pilosa":[153],"selected":[155],"23":[158],"reported":[160],"by":[161,173,194,210],"showed":[167,218],"partial":[168],"inhibition":[169],"proteolytic":[171],"activity":[172,187,207,220],"S.":[177,184,197,202],"P.":[179,195,214,274],"M.":[181,199,211],"officinarum;":[185],"was":[188,208],"inhibited":[189,209],"at":[190],"highest":[192],"doses":[193],"reticulata;":[203],"hemolytic":[206],"esculenta":[212],"spiralis.":[215,275],"No":[216],"extract":[217],"antimicrobial":[219],"or":[221,242],"changes":[222],"venom's":[225],"electrophoretic":[226],"profile.":[227],"Conclusion:":[228],"validation":[230],"plant":[232],"can":[234],"contribute":[235],"search":[238],"new":[240],"therapies":[241],"adjuncts":[243],"results":[250],"constitute":[254],"first":[256,268],"ethno-botanical":[257],"Tolima":[262],"department":[263],"report":[265],"time":[269]},"counts_by_year":[],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2026-09-13T00:00:00"}