{"id":"https://openalex.org/W7212360906","doi":"https://doi.org/10.64898/2026.09.08.750101","title":"tTEscanR: A user-friendly integrative R package for quantifying and visualizing translation efficiency from sequencing data in diverse biological systems","display_name":"tTEscanR: A user-friendly integrative R package for quantifying and visualizing translation efficiency from sequencing data in diverse biological systems","publication_year":2026,"publication_date":"2026-09-12","ids":{"openalex":"https://openalex.org/W7212360906","doi":"https://doi.org/10.64898/2026.09.08.750101"},"language":"en","primary_location":{"id":"doi:10.64898/2026.09.08.750101","doi":"https://doi.org/10.64898/2026.09.08.750101","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.08.750101","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/09/12/2026.09.08.750101.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2026/09/12/2026.09.08.750101.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5151465906","display_name":"Ana Varas Sanchez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800139495","display_name":"Science for Life Laboratory","ror":"https://ror.org/04ev03g22","country_code":"SE","type":"facility","lineage":["https://openalex.org/I2800139495"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Ana Varas-S\u00e1nchez","raw_affiliation_strings":["Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Science for Life Laboratory, 171 11 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Science for Life Laboratory, 171 11 Stockholm, Sweden","institution_ids":["https://openalex.org/I2800139495","https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046330690","display_name":"Carlos J. Gallardo-Dodd","orcid":"https://orcid.org/0000-0002-6086-0550","observed_orcids":["https://orcid.org/0000-0002-6086-0550"]},"institutions":[{"id":"https://openalex.org/I2800139495","display_name":"Science for Life Laboratory","ror":"https://ror.org/04ev03g22","country_code":"SE","type":"facility","lineage":["https://openalex.org/I2800139495"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Carlos J. Gallardo-Dodd","raw_affiliation_strings":["Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Science for Life Laboratory, 171 11 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Science for Life Laboratory, 171 11 Stockholm, Sweden","institution_ids":["https://openalex.org/I2800139495","https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5127284695","display_name":"Qun Li","orcid":"https://orcid.org/0000-0002-4734-712X","observed_orcids":["https://orcid.org/0000-0002-4734-712X"]},"institutions":[{"id":"https://openalex.org/I2800139495","display_name":"Science for Life Laboratory","ror":"https://ror.org/04ev03g22","country_code":"SE","type":"facility","lineage":["https://openalex.org/I2800139495"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Qun Li","raw_affiliation_strings":["Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Science for Life Laboratory, 171 11 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Science for Life Laboratory, 171 11 Stockholm, Sweden","institution_ids":["https://openalex.org/I2800139495","https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5132979852","display_name":"William Gao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800139495","display_name":"Science for Life Laboratory","ror":"https://ror.org/04ev03g22","country_code":"SE","type":"facility","lineage":["https://openalex.org/I2800139495"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"William Gao","raw_affiliation_strings":["Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Science for Life Laboratory, 171 11 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Science for Life Laboratory, 171 11 Stockholm, Sweden","institution_ids":["https://openalex.org/I2800139495","https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028075419","display_name":"Markus Ringn\u00e9r","orcid":"https://orcid.org/0000-0001-5469-8940","observed_orcids":["https://orcid.org/0000-0001-5469-8940"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I2800139495","display_name":"Science for Life Laboratory","ror":"https://ror.org/04ev03g22","country_code":"SE","type":"facility","lineage":["https://openalex.org/I2800139495"]},{"id":"https://openalex.org/I4387154792","display_name":"National Bioinformatics Infrastructure Sweden","ror":"https://ror.org/00enajs79","country_code":"SE","type":"other","lineage":["https://openalex.org/I123387679","https://openalex.org/I4387153960","https://openalex.org/I4387154792"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Markus Ringn\u00e9r","raw_affiliation_strings":["Department of Biology, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Lund University, 223 62 Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Lund University, 223 62 Lund, Sweden","institution_ids":["https://openalex.org/I187531555","https://openalex.org/I2800139495","https://openalex.org/I4387154792"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041673210","display_name":"Claudia Kutter","orcid":"https://orcid.org/0000-0002-8047-0058","observed_orcids":["https://orcid.org/0000-0002-8047-0058"]},"institutions":[{"id":"https://openalex.org/I2800139495","display_name":"Science for Life Laboratory","ror":"https://ror.org/04ev03g22","country_code":"SE","type":"facility","lineage":["https://openalex.org/I2800139495"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Claudia Kutter","raw_affiliation_strings":["Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Science for Life Laboratory, 171 11 Stockholm, Sweden"],"raw_orcid":"https://orcid.org/0000-0002-8047-0058","affiliations":[{"raw_affiliation_string":"Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Science for Life Laboratory, 171 11 Stockholm, Sweden","institution_ids":["https://openalex.org/I2800139495","https://openalex.org/I28166907"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5041673210"],"corresponding_institution_ids":["https://openalex.org/I2800139495","https://openalex.org/I28166907"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/translation-efficiency","display_name":"translation efficiency","score":0.902999997138977},{"id":"https://openalex.org/keywords/codon-anticodon-pairing","display_name":"codon-anticodon pairing","score":0.8899999856948853},{"id":"https://openalex.org/keywords/translation-elongation","display_name":"translation elongation","score":0.7200000286102295},{"id":"https://openalex.org/keywords/r-package","display_name":"R package","score":0.8640000224113464},{"id":"https://openalex.org/keywords/single-cell-transcriptomics","display_name":"single-cell transcriptomics","score":0.7860000133514404},{"id":"https://openalex.org/keywords/chromatin-accessibility","display_name":"chromatin accessibility","score":0.9710000157356262},{"id":"https://openalex.org/keywords/translational-control","display_name":"translational regulation","score":0.6579999923706055},{"id":"https://openalex.org/keywords/cancer","display_name":"cancer","score":0.6620000004768372},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.9819999933242798},{"id":"https://openalex.org/keywords/neurodegeneration","display_name":"neurodegeneration","score":1.0}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7426000237464905},{"id":"https://openalex.org/C177212765","wikidata":"https://www.wikidata.org/wiki/Q627335","display_name":"Workflow","level":2,"score":0.7278000116348267},{"id":"https://openalex.org/C101468663","wikidata":"https://www.wikidata.org/wiki/Q1620158","display_name":"Modular design","level":2,"score":0.6621000170707703},{"id":"https://openalex.org/C48044578","wikidata":"https://www.wikidata.org/wiki/Q727490","display_name":"Scalability","level":2,"score":0.570900022983551},{"id":"https://openalex.org/C149364088","wikidata":"https://www.wikidata.org/wiki/Q185917","display_name":"Translation (biology)","level":4,"score":0.5052000284194946},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.48350000381469727},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4715999960899353},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4357999861240387},{"id":"https://openalex.org/C2775992057","wikidata":"https://www.wikidata.org/wiki/Q16956568","display_name":"Translational efficiency","level":5,"score":0.4260999858379364},{"id":"https://openalex.org/C91632574","wikidata":"https://www.wikidata.org/wiki/Q15088675","display_name":"Data curation","level":2,"score":0.4146000146865845},{"id":"https://openalex.org/C172367668","wikidata":"https://www.wikidata.org/wiki/Q6504956","display_name":"Data visualization","level":3,"score":0.38040000200271606},{"id":"https://openalex.org/C59732488","wikidata":"https://www.wikidata.org/wiki/Q2528440","display_name":"Visual analytics","level":3,"score":0.3767000138759613},{"id":"https://openalex.org/C2777002779","wikidata":"https://www.wikidata.org/wiki/Q42478","display_name":"Perl","level":2,"score":0.35179999470710754},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.3407999873161316},{"id":"https://openalex.org/C2780385302","wikidata":"https://www.wikidata.org/wiki/Q367158","display_name":"Protocol (science)","level":3,"score":0.3361999988555908},{"id":"https://openalex.org/C201797286","wikidata":"https://www.wikidata.org/wiki/Q4914986","display_name":"Biological data","level":2,"score":0.3253999948501587},{"id":"https://openalex.org/C128544194","wikidata":"https://www.wikidata.org/wiki/Q474859","display_name":"Translational research","level":2,"score":0.32519999146461487},{"id":"https://openalex.org/C49937458","wikidata":"https://www.wikidata.org/wiki/Q2599292","display_name":"Probabilistic logic","level":2,"score":0.3158000111579895},{"id":"https://openalex.org/C114289077","wikidata":"https://www.wikidata.org/wiki/Q3284399","display_name":"Statistical model","level":2,"score":0.31520000100135803},{"id":"https://openalex.org/C24756922","wikidata":"https://www.wikidata.org/wiki/Q1757694","display_name":"Data quality","level":3,"score":0.31439998745918274},{"id":"https://openalex.org/C5274069","wikidata":"https://www.wikidata.org/wiki/Q2285707","display_name":"Categorical variable","level":2,"score":0.3059999942779541},{"id":"https://openalex.org/C2779530757","wikidata":"https://www.wikidata.org/wiki/Q1207505","display_name":"Quality (philosophy)","level":2,"score":0.30149999260902405},{"id":"https://openalex.org/C61423126","wikidata":"https://www.wikidata.org/wiki/Q187432","display_name":"Scripting language","level":2,"score":0.29760000109672546},{"id":"https://openalex.org/C2984074130","wikidata":"https://www.wikidata.org/wiki/Q73539779","display_name":"R package","level":2,"score":0.29440000653266907},{"id":"https://openalex.org/C20136886","wikidata":"https://www.wikidata.org/wiki/Q749647","display_name":"Interoperability","level":2,"score":0.29159998893737793},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.2840999960899353},{"id":"https://openalex.org/C4718897","wikidata":"https://www.wikidata.org/wiki/Q5408698","display_name":"Eukaryotic translation","level":5,"score":0.26649999618530273},{"id":"https://openalex.org/C2781238097","wikidata":"https://www.wikidata.org/wiki/Q175026","display_name":"Object (grammar)","level":2,"score":0.2644999921321869},{"id":"https://openalex.org/C79158427","wikidata":"https://www.wikidata.org/wiki/Q485396","display_name":"Analytics","level":2,"score":0.2522999942302704},{"id":"https://openalex.org/C37789001","wikidata":"https://www.wikidata.org/wiki/Q782543","display_name":"Graphical user interface","level":2,"score":0.25110000371932983}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.09.08.750101","doi":"https://doi.org/10.64898/2026.09.08.750101","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.08.750101","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/09/12/2026.09.08.750101.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.64898/2026.09.08.750101","doi":"https://doi.org/10.64898/2026.09.08.750101","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.09.08.750101","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/09/12/2026.09.08.750101.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321491","display_name":"Cancerfonden","ror":"https://ror.org/0527jb766"},{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7212360906.pdf","grobid_xml":"https://content.openalex.org/works/W7212360906.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W252557772","https://openalex.org/W1966413612","https://openalex.org/W2021035007","https://openalex.org/W2045949302","https://openalex.org/W2055639102","https://openalex.org/W2079517684","https://openalex.org/W2080757130","https://openalex.org/W2087846512","https://openalex.org/W2175136759","https://openalex.org/W2179438025","https://openalex.org/W2223836536","https://openalex.org/W2378488822","https://openalex.org/W2572271818","https://openalex.org/W2742715352","https://openalex.org/W2751076435","https://openalex.org/W2886956635","https://openalex.org/W2942678593","https://openalex.org/W3048999744","https://openalex.org/W3130039809","https://openalex.org/W3133557863","https://openalex.org/W3184296406","https://openalex.org/W3216676606","https://openalex.org/W4281624786","https://openalex.org/W4282048623","https://openalex.org/W4306173528","https://openalex.org/W4319293859","https://openalex.org/W4362673466","https://openalex.org/W4378212544","https://openalex.org/W4387142594","https://openalex.org/W4387568450","https://openalex.org/W4387568710","https://openalex.org/W4388722346","https://openalex.org/W4389174400","https://openalex.org/W4389240721","https://openalex.org/W4389955963","https://openalex.org/W4390663488","https://openalex.org/W4391944521","https://openalex.org/W4401806028","https://openalex.org/W4402466470","https://openalex.org/W4402912676","https://openalex.org/W4405965123","https://openalex.org/W4406619077"],"related_works":["https://openalex.org/W4416121729","https://openalex.org/W2765095070","https://openalex.org/W3124364457","https://openalex.org/W2952390442","https://openalex.org/W2980897189","https://openalex.org/W2157953265","https://openalex.org/W4412707601","https://openalex.org/W6965026503","https://openalex.org/W2770935577","https://openalex.org/W2016214324"],"abstract_inverted_index":{"Abstract":[0,1],"Figure":[2],"Graphical":[3],"abstract":[4],"Translation":[5],"elongation":[6],"relies":[7],"on":[8],"accurate":[9],"codon-anticodon":[10],"pairing.":[11],"Here,":[12],"we":[13],"present":[14],"tTEscanR,":[15],"an":[16,141],"R":[17],"package":[18],"designed":[19],"to":[20,104],"investigate":[21],"this":[22],"translational":[23,113,130],"interface.":[24],"By":[25],"quantifying":[26],"mRNA":[27],"codon":[28],"demand":[29],"alongside":[30],"tRNA":[31],"anticodon":[32],"availability,":[33],"tTEscanR":[34,62,120,137],"provides":[35,72],"scalable":[36],"estimates":[37],"of":[38,110,119],"translation":[39],"rates":[40],"directly":[41],"from":[42],"standard":[43],"transcriptomic":[44],"and":[45,57,68,71,82,91,108,125],"chromatin":[46],"accessibility":[47],"count":[48],"matrices,":[49],"where":[50],"genomic":[51],"features":[52],"are":[53],"represented":[54],"as":[55,60,144],"rows":[56],"experimental":[58],"conditions":[59],"columns.":[61],"seamlessly":[63],"integrates":[64],"into":[65],"existing":[66],"bulk":[67],"single-cell":[69],"pipelines":[70],"modular":[73],"functions":[74],"for":[75],"quality":[76],"control,":[77],"filtering,":[78],"normalization,":[79],"statistical":[80],"analysis,":[81],"visualization.":[83],"A":[84,94],"structured":[85],"data":[86,106],"object":[87],"centralizes":[88],"workflow":[89,149],"outputs":[90,103],"associated":[92],"metadata.":[93],"built-in":[95],"multilevel":[96],"visualization":[97],"module":[98],"generates":[99],"customizable,":[100],"publication-ready":[101],"graphical":[102],"facilitate":[105],"interpretation":[107],"reproducibility":[109],"the":[111,117],"complex":[112],"landscape.":[114],"We":[115],"demonstrate":[116],"utility":[118],"across":[121],"cancer":[122],"biology,":[123],"aging,":[124],"neurodegeneration":[126],"datasets,":[127],"uncovering":[128],"critical":[129],"regulatory":[131],"programs":[132],"overlooked":[133],"by":[134],"conventional":[135],"analyses.":[136],"is":[138],"available":[139],"in":[140],"open-source":[142],"repository":[143],"a":[145],"standalone":[146],"tool":[147],"or":[148],"plug-in.":[150]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-09-13T00:00:00"}