{"id":"https://openalex.org/W7212112477","doi":"https://doi.org/10.1016/j.jaccas.2026.110273","title":"Late Anthracycline Cardiotoxicity Mimicking Arrhythmogenic Cardiomyopathy in a Young Adult","display_name":"Late Anthracycline Cardiotoxicity Mimicking Arrhythmogenic Cardiomyopathy in a Young Adult","publication_year":2026,"publication_date":"2026-09-11","ids":{"openalex":"https://openalex.org/W7212112477","doi":"https://doi.org/10.1016/j.jaccas.2026.110273","pmid":"https://pubmed.ncbi.nlm.nih.gov/42726042","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13699096"},"language":"en","primary_location":{"id":"doi:10.1016/j.jaccas.2026.110273","doi":"https://doi.org/10.1016/j.jaccas.2026.110273","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaccas.2026.110273","pdf_url":"https://www.jacc.org/doi/pdf/10.1016/j.jaccas.2026.110273?download=true","source":{"id":"https://openalex.org/S4210180918","display_name":"JACC Case Reports","issn_l":"2666-0849","issn":["2666-0849"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JACC: Case Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.jacc.org/doi/pdf/10.1016/j.jaccas.2026.110273?download=true","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009002878","display_name":"Maroun Chedid","orcid":"https://orcid.org/0009-0001-2604-1121","observed_orcids":["https://orcid.org/0009-0001-2604-1121"]},"institutions":[{"id":"https://openalex.org/I1319743688","display_name":"Abbott Northwestern Hospital","ror":"https://ror.org/01fzm0693","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1319743688","https://openalex.org/I1326929380"]},{"id":"https://openalex.org/I1326929380","display_name":"Allina Health","ror":"https://ror.org/04esegk75","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1326929380"]},{"id":"https://openalex.org/I4210134111","display_name":"Minneapolis Heart Institute Foundation","ror":"https://ror.org/03mhcky17","country_code":"US","type":"other","lineage":["https://openalex.org/I4210134111"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Maroun Chedid","raw_affiliation_strings":["Allina Health Minneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, Minnesota, USA; Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA. Electronic address: maroun.chedid@hcmed.org"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Allina Health Minneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, Minnesota, USA; Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA. Electronic address: maroun.chedid@hcmed.org","institution_ids":["https://openalex.org/I1319743688","https://openalex.org/I1326929380","https://openalex.org/I4210134111"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5099774303","display_name":"Collin M. Barrett","orcid":"https://orcid.org/0009-0004-3891-6476","observed_orcids":["https://orcid.org/0009-0004-3891-6476"]},"institutions":[{"id":"https://openalex.org/I1319743688","display_name":"Abbott Northwestern Hospital","ror":"https://ror.org/01fzm0693","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1319743688","https://openalex.org/I1326929380"]},{"id":"https://openalex.org/I1326929380","display_name":"Allina Health","ror":"https://ror.org/04esegk75","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1326929380"]},{"id":"https://openalex.org/I4210134111","display_name":"Minneapolis Heart Institute Foundation","ror":"https://ror.org/03mhcky17","country_code":"US","type":"other","lineage":["https://openalex.org/I4210134111"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Collin Barrett","raw_affiliation_strings":["Allina Health Minneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, Minnesota, USA; Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Allina Health Minneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, Minnesota, USA; Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA","institution_ids":["https://openalex.org/I1319743688","https://openalex.org/I1326929380","https://openalex.org/I4210134111"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5151168405","display_name":"Melanie Sun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134111","display_name":"Minneapolis Heart Institute Foundation","ror":"https://ror.org/03mhcky17","country_code":"US","type":"other","lineage":["https://openalex.org/I4210134111"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Melanie Sun","raw_affiliation_strings":["Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA","institution_ids":["https://openalex.org/I4210134111"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011441559","display_name":"Andrew M. Lesser","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1319743688","display_name":"Abbott Northwestern Hospital","ror":"https://ror.org/01fzm0693","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1319743688","https://openalex.org/I1326929380"]},{"id":"https://openalex.org/I1326929380","display_name":"Allina Health","ror":"https://ror.org/04esegk75","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1326929380"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew Lesser","raw_affiliation_strings":["Allina Health Minneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Allina Health Minneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, Minnesota, USA","institution_ids":["https://openalex.org/I1319743688","https://openalex.org/I1326929380"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5151207350","display_name":"Katarxyna Hryniewicz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1319743688","display_name":"Abbott Northwestern Hospital","ror":"https://ror.org/01fzm0693","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1319743688","https://openalex.org/I1326929380"]},{"id":"https://openalex.org/I1326929380","display_name":"Allina Health","ror":"https://ror.org/04esegk75","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1326929380"]},{"id":"https://openalex.org/I4210134111","display_name":"Minneapolis Heart Institute Foundation","ror":"https://ror.org/03mhcky17","country_code":"US","type":"other","lineage":["https://openalex.org/I4210134111"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katarxyna Hryniewicz","raw_affiliation_strings":["Allina Health Minneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, Minnesota, USA; Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Allina Health Minneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, Minnesota, USA; Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA","institution_ids":["https://openalex.org/I1319743688","https://openalex.org/I1326929380","https://openalex.org/I4210134111"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5009002878"],"corresponding_institution_ids":["https://openalex.org/I1319743688","https://openalex.org/I1326929380","https://openalex.org/I4210134111"],"apc_list":{"value":850,"currency":"USD","value_usd":850},"apc_paid":{"value":850,"currency":"USD","value_usd":850},"fwci":4.0135,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.95318671,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"31","issue":"42","first_page":"110273","last_page":"110273"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11535","display_name":"Chemotherapy-induced cardiotoxicity and mitigation","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11535","display_name":"Chemotherapy-induced cardiotoxicity and mitigation","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11922","display_name":"Cardiovascular Effects of Exercise","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/anthracycline-induced-cardiotoxicity","display_name":"anthracycline cardiotoxicity","score":0.9279999732971191},{"id":"https://openalex.org/keywords/doxorubicin","display_name":"doxorubicin","score":0.9789999723434448},{"id":"https://openalex.org/keywords/late-cardiotoxicity","display_name":"late cardiotoxicity","score":0.8479999899864197},{"id":"https://openalex.org/keywords/arrhythmogenic-cardiomyopathy","display_name":"arrhythmogenic cardiomyopathy","score":0.9620000123977661},{"id":"https://openalex.org/keywords/cancer-survivors","display_name":"cancer survivors","score":0.5429999828338623},{"id":"https://openalex.org/keywords/young-adults","display_name":"young adults","score":0.5820000171661377},{"id":"https://openalex.org/keywords/global-longitudinal-strain","display_name":"global longitudinal strain","score":0.6299999952316284},{"id":"https://openalex.org/keywords/late-gadolinium-enhancement","display_name":"late gadolinium enhancement","score":0.8920000195503235},{"id":"https://openalex.org/keywords/mechanical-dyssynchrony","display_name":"mechanical dyssynchrony","score":0.8429999947547913},{"id":"https://openalex.org/keywords/cardiac-magnetic-resonance","display_name":"cardiac magnetic resonance","score":0.7020000219345093},{"id":"https://openalex.org/keywords/exercise-stress-test","display_name":"exercise stress testing","score":0.671999990940094}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8388000130653381},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.7279000282287598},{"id":"https://openalex.org/C2778797674","wikidata":"https://www.wikidata.org/wiki/Q847583","display_name":"Cardiomyopathy","level":3,"score":0.7200000286102295},{"id":"https://openalex.org/C2778233292","wikidata":"https://www.wikidata.org/wiki/Q2118956","display_name":"Cardiotoxicity","level":3,"score":0.7131999731063843},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6794999837875366},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5752999782562256},{"id":"https://openalex.org/C2776802502","wikidata":"https://www.wikidata.org/wiki/Q417589","display_name":"Anthracycline","level":4,"score":0.4499000012874603},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.336899995803833},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.3127000033855438},{"id":"https://openalex.org/C2780185194","wikidata":"https://www.wikidata.org/wiki/Q1364270","display_name":"Hypertrophic cardiomyopathy","level":2,"score":0.3118000030517578},{"id":"https://openalex.org/C2780040984","wikidata":"https://www.wikidata.org/wiki/Q79785","display_name":"Electrocardiography","level":2,"score":0.2612000107765198}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1016/j.jaccas.2026.110273","doi":"https://doi.org/10.1016/j.jaccas.2026.110273","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaccas.2026.110273","pdf_url":"https://www.jacc.org/doi/pdf/10.1016/j.jaccas.2026.110273?download=true","source":{"id":"https://openalex.org/S4210180918","display_name":"JACC Case Reports","issn_l":"2666-0849","issn":["2666-0849"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JACC: Case Reports","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13699096","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13699096/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13699096/pdf/main.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JACC Case Rep","raw_type":"Text"},{"id":"pmid:42726042","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42726042","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JACC. Case reports","raw_type":"Case Reports"},{"id":"pmh:oai:doaj.org/article:d1ed91ca818340e981e826b867da86e6","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/d1ed91ca818340e981e826b867da86e6","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"JACC: Case Reports, Vol 31, Iss 42, Pp 110273- (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.jaccas.2026.110273","doi":"https://doi.org/10.1016/j.jaccas.2026.110273","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaccas.2026.110273","pdf_url":"https://www.jacc.org/doi/pdf/10.1016/j.jaccas.2026.110273?download=true","source":{"id":"https://openalex.org/S4210180918","display_name":"JACC Case Reports","issn_l":"2666-0849","issn":["2666-0849"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JACC: Case Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7212112477.pdf","grobid_xml":"https://content.openalex.org/works/W7212112477.grobid-xml"},"referenced_works_count":9,"referenced_works":["https://openalex.org/W2055312115","https://openalex.org/W2125052019","https://openalex.org/W2131810639","https://openalex.org/W2806157730","https://openalex.org/W4402564261","https://openalex.org/W4403426073","https://openalex.org/W4406899571","https://openalex.org/W4407768149","https://openalex.org/W4413773202"],"related_works":["https://openalex.org/W1556114568","https://openalex.org/W3032582171","https://openalex.org/W3192971682","https://openalex.org/W7123525131","https://openalex.org/W2557234389","https://openalex.org/W2007337980","https://openalex.org/W2056809452","https://openalex.org/W1997900909","https://openalex.org/W2801862857","https://openalex.org/W1993593737"],"abstract_inverted_index":{"BACKGROUND:":[0],"Doxorubicin-induced":[1],"cardiotoxicity":[2,22,101,124],"can":[3],"manifest":[4],"years":[5],"after":[6],"exposure":[7],"and":[8,35,39,70,83,110],"may":[9,102],"mimic":[10,105],"other":[11,111],"cardiomyopathies":[12],"in":[13,24,125],"young":[14,126],"patients,":[15],"making":[16],"the":[17],"diagnosis":[18],"of":[19,118],"delayed":[20],"doxorubicin":[21],"challenging":[23],"these":[25],"patients.":[26],"CASE":[27],"SUMMARY:":[28],"cumulative)":[29],"presented":[30],"with":[31,64],"exertional":[32],"chest":[33],"discomfort":[34],"palpitations.":[36],"Resting":[37],"electrocardiogram":[38],"ambulatory":[40],"monitoring":[41],"were":[42],"unremarkable.":[43],"Transthoracic":[44],"echocardiography":[45],"demonstrated":[46,76],"preserved":[47],"ejection":[48],"fraction":[49],"(55%-60%)":[50],"but":[51],"reduced":[52,71],"global":[53],"longitudinal":[54],"strain":[55],"(-15%).":[56],"Cardiac":[57],"magnetic":[58],"resonance":[59],"revealed":[60],"low-normal":[61],"biventricular":[62],"function":[63],"nonischemic":[65],"septal":[66,80],"late":[67,123],"gadolinium":[68],"enhancement":[69],"strain.":[72],"Exercise":[73],"stress":[74],"testing":[75],"impaired":[77],"contractile":[78],"reserve,":[79],"mechanical":[81],"dyssynchrony,":[82],"exercise-induced":[84],"QRS":[85],"prolongation.":[86],"Coronary":[87],"computed":[88],"tomography":[89],"angiography":[90],"excluded":[91],"coronary":[92],"artery":[93],"disease.":[94],"DISCUSSION:":[95],"This":[96],"case":[97],"highlights":[98],"that":[99],"anthracycline":[100],"present":[103],"late,":[104],"myocardial":[106],"ischemia,":[107],"arrhythmogenic":[108],"cardiomyopathy,":[109],"cardiomyopathies.":[112],"TAKE-HOME":[113],"MESSAGE:":[114],"A":[115],"high":[116],"index":[117],"suspicion":[119],"is":[120],"required":[121],"for":[122],"cancer":[127],"survivors.":[128]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2026-09-11T00:00:00"}