{"id":"https://openalex.org/W7212036330","doi":"https://doi.org/10.1016/j.xkme.2026.101519","title":"Epimeric Vitamin D is Not Associated With Arterial Stiffness or Cardiovascular Outcomes in Patients With Advanced CKD","display_name":"Epimeric Vitamin D is Not Associated With Arterial Stiffness or Cardiovascular Outcomes in Patients With Advanced CKD","publication_year":2026,"publication_date":"2026-09-09","ids":{"openalex":"https://openalex.org/W7212036330","doi":"https://doi.org/10.1016/j.xkme.2026.101519","pmid":"https://pubmed.ncbi.nlm.nih.gov/42894851","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13677220"},"language":"en","primary_location":{"id":"doi:10.1016/j.xkme.2026.101519","doi":"https://doi.org/10.1016/j.xkme.2026.101519","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.xkme.2026.101519","pdf_url":"https://www.kidneymedicinejournal.org/article/S2590-0595(26)00281-5/pdf","source":{"id":"https://openalex.org/S4210206143","display_name":"Kidney Medicine","issn_l":"2590-0595","issn":["2590-0595"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.kidneymedicinejournal.org/article/S2590-0595(26)00281-5/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030332598","display_name":"Monique Opuszcka Campos","orcid":"https://orcid.org/0000-0001-9526-0937","observed_orcids":["https://orcid.org/0000-0001-9526-0937"]},"institutions":[{"id":"https://openalex.org/I4388446366","display_name":"Indiana University Indianapolis","ror":"https://ror.org/03eftgw80","country_code":"US","type":"education","lineage":["https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Monique O. Campos","raw_affiliation_strings":["Division of Nephrology & Hypertension, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology & Hypertension, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091695262","display_name":"Chien\u2010Yao Sun","orcid":"https://orcid.org/0000-0001-6236-6022","observed_orcids":["https://orcid.org/0000-0001-6236-6022"]},"institutions":[{"id":"https://openalex.org/I4210158999","display_name":"National Cheng Kung University Hospital","ror":"https://ror.org/04zx3rq17","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210158999"]},{"id":"https://openalex.org/I4388446366","display_name":"Indiana University Indianapolis","ror":"https://ror.org/03eftgw80","country_code":"US","type":"education","lineage":["https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]},{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["TW","US"],"is_corresponding":false,"raw_author_name":"Chien-Yao Sun","raw_affiliation_strings":["Department of Geriatric and Gerontology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan","Division of Nephrology & Hypertension, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN","Institute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatric and Gerontology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan","institution_ids":["https://openalex.org/I4210158999","https://openalex.org/I91807558"]},{"raw_affiliation_string":"Division of Nephrology & Hypertension, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130"]},{"raw_affiliation_string":"Institute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan","institution_ids":["https://openalex.org/I91807558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023777024","display_name":"Heather N. Burney","orcid":"https://orcid.org/0009-0009-9440-1158","observed_orcids":["https://orcid.org/0009-0009-9440-1158"]},"institutions":[{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heather N. Burney","raw_affiliation_strings":["Department of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN","institution_ids":["https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100421306","display_name":"Yang Li","orcid":"https://orcid.org/0000-0001-7024-7103","observed_orcids":["https://orcid.org/0000-0001-7024-7103"]},"institutions":[{"id":"https://openalex.org/I4388446366","display_name":"Indiana University Indianapolis","ror":"https://ror.org/03eftgw80","country_code":"US","type":"education","lineage":["https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]},{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yang Li","raw_affiliation_strings":["Department of Biostatistics and Health Data Science and Richard M. Fairbanks School of Public Health, Indiana University School of Medicine, Indianapolis, IN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics and Health Data Science and Richard M. Fairbanks School of Public Health, Indiana University School of Medicine, Indianapolis, IN","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130","https://openalex.org/I55769427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007768372","display_name":"Gayatri Narayanan","orcid":"https://orcid.org/0000-0002-5091-4092","observed_orcids":["https://orcid.org/0000-0002-5091-4092"]},"institutions":[{"id":"https://openalex.org/I4388446366","display_name":"Indiana University Indianapolis","ror":"https://ror.org/03eftgw80","country_code":"US","type":"education","lineage":["https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gayatri Narayanan","raw_affiliation_strings":["Division of Nephrology & Hypertension, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology & Hypertension, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033955406","display_name":"Olivia Carlton","orcid":"https://orcid.org/0000-0002-6880-4596","observed_orcids":["https://orcid.org/0000-0002-6880-4596"]},"institutions":[{"id":"https://openalex.org/I4388446366","display_name":"Indiana University Indianapolis","ror":"https://ror.org/03eftgw80","country_code":"US","type":"education","lineage":["https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Olivia Carlton","raw_affiliation_strings":["Division of Nephrology & Hypertension, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology & Hypertension, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047820165","display_name":"Tzongshi Lu","orcid":"https://orcid.org/0000-0002-3115-5000","observed_orcids":["https://orcid.org/0000-0002-3115-5000"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tzong-Shi Lu","raw_affiliation_strings":["Renal Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Renal Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013460050","display_name":"Glenville Jones","orcid":"https://orcid.org/0000-0001-7402-3473","observed_orcids":["https://orcid.org/0000-0001-7402-3473"]},"institutions":[{"id":"https://openalex.org/I204722609","display_name":"Queen's University","ror":"https://ror.org/02y72wh86","country_code":"CA","type":"education","lineage":["https://openalex.org/I204722609"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Glenville Jones","raw_affiliation_strings":["Department of Biomedical and Molecular Sciences and Medicine, Queen's University, Kingston, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical and Molecular Sciences and Medicine, Queen's University, Kingston, Ontario, Canada","institution_ids":["https://openalex.org/I204722609"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5129479511","display_name":"Martin Kaufmann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204722609","display_name":"Queen's University","ror":"https://ror.org/02y72wh86","country_code":"CA","type":"education","lineage":["https://openalex.org/I204722609"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Martin Kaufmann","raw_affiliation_strings":["Department of Biomedical and Molecular Sciences and Medicine, Queen's University, Kingston, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical and Molecular Sciences and Medicine, Queen's University, Kingston, Ontario, Canada","institution_ids":["https://openalex.org/I204722609"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088341309","display_name":"Stephen M. S. Ting","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1308923049","display_name":"University Hospitals Birmingham NHS Foundation Trust","ror":"https://ror.org/014ja3n03","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1308923049"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stephen M.S. Ting","raw_affiliation_strings":["Department of Medicine, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK","institution_ids":["https://openalex.org/I1308923049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075161165","display_name":"Daniel Zehnder","orcid":"https://orcid.org/0000-0003-1356-2232","observed_orcids":["https://orcid.org/0000-0003-1356-2232"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel Zehnder","raw_affiliation_strings":["Department of Nephrology and Department of Acute Medicine, North Cumbria University Hospital NHS Trust, Carlisle, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology and Department of Acute Medicine, North Cumbria University Hospital NHS Trust, Carlisle, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021117584","display_name":"Thomas F. Hiemstra","orcid":"https://orcid.org/0000-0002-2115-8689","observed_orcids":["https://orcid.org/0000-0002-2115-8689"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I4405267003","display_name":"Cambridge Clinical Trials Unit","ror":"https://ror.org/00s06sw72","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4405267003"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Thomas Hiemstra","raw_affiliation_strings":["Cambridge Clinical Trials Unit and School of Clinical Medicine, University of Cambridge, Cambridge, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cambridge Clinical Trials Unit and School of Clinical Medicine, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I241749","https://openalex.org/I4405267003"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017570289","display_name":"Kenneth J. Lim","orcid":"https://orcid.org/0000-0001-7178-2183","observed_orcids":["https://orcid.org/0000-0001-7178-2183"]},"institutions":[{"id":"https://openalex.org/I4388446366","display_name":"Indiana University Indianapolis","ror":"https://ror.org/03eftgw80","country_code":"US","type":"education","lineage":["https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Kenneth Lim","raw_affiliation_strings":["Division of Nephrology & Hypertension, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN"],"raw_orcid":"https://orcid.org/0000-0001-7178-2183","affiliations":[{"raw_affiliation_string":"Division of Nephrology & Hypertension, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5017570289"],"corresponding_institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130"],"apc_list":{"value":2590,"currency":"USD","value_usd":2590},"apc_paid":{"value":2590,"currency":"USD","value_usd":2590},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.61910122,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"8","issue":"11","first_page":"101519","last_page":"101519"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.41940000653266907,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.41940000653266907,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.2824999988079071,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.2556000053882599,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/advanced-chronic-kidney-disease","display_name":"advanced chronic kidney disease","score":0.7680000066757202},{"id":"https://openalex.org/keywords/arterial-stiffness","display_name":"arterial stiffness","score":0.949999988079071},{"id":"https://openalex.org/keywords/cardiovascular-outcomes","display_name":"cardiovascular outcomes","score":0.7450000047683716},{"id":"https://openalex.org/keywords/pulse-wave-velocity","display_name":"pulse wave velocity","score":0.7720000147819519},{"id":"https://openalex.org/keywords/augmentation-index","display_name":"augmentation index","score":0.9929999709129333},{"id":"https://openalex.org/keywords/major-adverse-cardiovascular-events","display_name":"major adverse cardiovascular events","score":0.7730000019073486},{"id":"https://openalex.org/keywords/all-cause-mortality","display_name":"all-cause mortality","score":0.9789999723434448},{"id":"https://openalex.org/keywords/vitamin-d-metabolism","display_name":"vitamin D metabolism","score":0.49900001287460327},{"id":"https://openalex.org/keywords/hemodialysis","display_name":"hemodialysis","score":0.6729999780654907},{"id":"https://openalex.org/keywords/peritoneal-dialysis","display_name":"peritoneal dialysis","score":0.9319999814033508},{"id":"https://openalex.org/keywords/end-stage-renal-disease","display_name":"end-stage renal disease","score":0.6230000257492065},{"id":"https://openalex.org/keywords/vascular-health","display_name":"vascular health","score":0.35600000619888306},{"id":"https://openalex.org/keywords/racial-differences","display_name":"racial differences","score":0.4440000057220459}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7462999820709229},{"id":"https://openalex.org/C2775850156","wikidata":"https://www.wikidata.org/wiki/Q4797538","display_name":"Arterial stiffness","level":3,"score":0.6633999943733215},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6322000026702881},{"id":"https://openalex.org/C124490489","wikidata":"https://www.wikidata.org/wiki/Q7936963","display_name":"Vitamin D and neurology","level":2,"score":0.6205999851226807},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.505299985408783},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.38179999589920044},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.32850000262260437},{"id":"https://openalex.org/C3018348675","wikidata":"https://www.wikidata.org/wiki/Q4797557","display_name":"Arterial disease","level":3,"score":0.3240000009536743},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.3158999979496002},{"id":"https://openalex.org/C2779372316","wikidata":"https://www.wikidata.org/wiki/Q569057","display_name":"Stiffness","level":2,"score":0.31040000915527344},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.2867000102996826},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.2791000008583069},{"id":"https://openalex.org/C2778319312","wikidata":"https://www.wikidata.org/wiki/Q2118022","display_name":"Pulse wave velocity","level":3,"score":0.2786000072956085},{"id":"https://openalex.org/C2776940978","wikidata":"https://www.wikidata.org/wiki/Q34956","display_name":"Vitamin","level":2,"score":0.27799999713897705},{"id":"https://openalex.org/C3020090656","wikidata":"https://www.wikidata.org/wiki/Q9655","display_name":"Arterial wall","level":2,"score":0.26589998602867126},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.2614000141620636},{"id":"https://openalex.org/C57900726","wikidata":"https://www.wikidata.org/wiki/Q492905","display_name":"Diastole","level":3,"score":0.2542000114917755},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.25040000677108765}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1016/j.xkme.2026.101519","doi":"https://doi.org/10.1016/j.xkme.2026.101519","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.xkme.2026.101519","pdf_url":"https://www.kidneymedicinejournal.org/article/S2590-0595(26)00281-5/pdf","source":{"id":"https://openalex.org/S4210206143","display_name":"Kidney Medicine","issn_l":"2590-0595","issn":["2590-0595"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13677220","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13677220/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13677220/pdf/main.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney Med","raw_type":"Text"},{"id":"pmid:42894851","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42894851","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney medicine","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:075ed456e4324fb8a150a233233aab26","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/075ed456e4324fb8a150a233233aab26","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Kidney Medicine, Vol 8, Iss 11, Pp 101519- (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.xkme.2026.101519","doi":"https://doi.org/10.1016/j.xkme.2026.101519","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.xkme.2026.101519","pdf_url":"https://www.kidneymedicinejournal.org/article/S2590-0595(26)00281-5/pdf","source":{"id":"https://openalex.org/S4210206143","display_name":"Kidney Medicine","issn_l":"2590-0595","issn":["2590-0595"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G2968882521","display_name":"Improvement in left ventricular geometry and cardiovascular functional capacity after restitution of the failing kidney through transplantation: a prospective non-randomised concurrent control study","funder_award_id":"PG/11/66/28982","funder_id":"https://openalex.org/F4320319992","funder_display_name":"British Heart Foundation"},{"id":"https://openalex.org/G9000906517","display_name":"Redefining cardiovascular risk assessment in dialysis patients (ROCK-D) study","funder_award_id":"R01HL166747","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320308347","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94"},{"id":"https://openalex.org/F4320314693","display_name":"University Hospitals Birmingham NHS Foundation Trust","ror":"https://ror.org/014ja3n03"},{"id":"https://openalex.org/F4320315856","display_name":"Dialysis Clinics","ror":"https://ror.org/058c2a318"},{"id":"https://openalex.org/F4320319992","display_name":"British Heart Foundation","ror":"https://ror.org/02wdwnk04"},{"id":"https://openalex.org/F4320321832","display_name":"Queen's University","ror":"https://ror.org/02y72wh86"},{"id":"https://openalex.org/F4320322933","display_name":"National Cheng Kung University Hospital","ror":"https://ror.org/04zx3rq17"},{"id":"https://openalex.org/F4320324663","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332961","display_name":"School of Medicine, Indiana University","ror":null},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7212036330.pdf","grobid_xml":"https://content.openalex.org/works/W7212036330.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W1966506433","https://openalex.org/W1976544899","https://openalex.org/W2026195740","https://openalex.org/W2026965880","https://openalex.org/W2030777261","https://openalex.org/W2041302995","https://openalex.org/W2050375253","https://openalex.org/W2054129325","https://openalex.org/W2069292441","https://openalex.org/W2069892521","https://openalex.org/W2078808411","https://openalex.org/W2097189035","https://openalex.org/W2127755180","https://openalex.org/W2143565640","https://openalex.org/W2144818521","https://openalex.org/W2151974901","https://openalex.org/W2157011913","https://openalex.org/W2328615536","https://openalex.org/W2513213858","https://openalex.org/W2513346131","https://openalex.org/W2771417658","https://openalex.org/W2900520180","https://openalex.org/W2905116893","https://openalex.org/W2923850321","https://openalex.org/W2968264927","https://openalex.org/W2998808413","https://openalex.org/W3005140551","https://openalex.org/W3048799679","https://openalex.org/W3081785901","https://openalex.org/W3101061271","https://openalex.org/W3124003341","https://openalex.org/W3134081776","https://openalex.org/W3153413504","https://openalex.org/W3197258213","https://openalex.org/W3198483773","https://openalex.org/W4214912959","https://openalex.org/W4292528167","https://openalex.org/W4384807097","https://openalex.org/W4390346330","https://openalex.org/W4402207157","https://openalex.org/W4406904347","https://openalex.org/W4407917618"],"related_works":["https://openalex.org/W4403811621","https://openalex.org/W4384807097","https://openalex.org/W4387061824","https://openalex.org/W2771417658","https://openalex.org/W3030448225","https://openalex.org/W7140321807","https://openalex.org/W4282546706","https://openalex.org/W2120773715","https://openalex.org/W3119690894","https://openalex.org/W4402207157"],"abstract_inverted_index":{"Rationale":[0],"&":[1,64],"Objective":[2],"3-epi-25(OH)D":[3,38,83,121,224,260,287],"3":[4,11,39,84,122,225,261,288],",":[5],"an":[6],"epimeric":[7,310],"form":[8],"of":[9,112,309],"25(OH)D":[10],"generated":[12],"by":[13,86,97,194],"C-3":[14],"epimerization,":[15],"declines":[16],"with":[17,43,68,229,279,293],"advancing":[18],"CKD,":[19,286],"yet":[20],"its":[21],"role":[22,308],"in":[23,51,183,313],"vascular":[24],"health":[25],"and":[26,46,56,103,116,137,141,172,188,206,269,299],"related":[27],"outcomes":[28,50,108],"remains":[29],"largely":[30],"unknown.":[31],"We":[32],"aimed":[33],"to":[34,305],"determine":[35,306],"whether":[36],"circulating":[37],"levels":[40],"are":[41,303],"associated":[42],"arterial":[44,294],"stiffness":[45,94,212,295],"longitudinal":[47,145],"cardiovascular":[48],"(CV)":[49],"advanced":[52,69,285],"CKD":[53,70,314],"(stages":[54],"5":[55],"5D).":[57],"Study":[58],"Design":[59],"Prospective":[60],"observational":[61],"study.":[62],"Setting":[63],"Participants":[65],"270":[66,149],"patients":[67],"using":[71,130,237],"the":[72,264,307],"Cambridge":[73],"Coventry":[74],"Vascular":[75],"Cohort.":[76],"Exposure":[77],"(s)":[78,81,92],"or":[79,231,234,296],"Predictor":[80],"Baseline":[82],"measured":[85],"liquid":[87],"chromatography\u2013tandem":[88],"mass":[89],"spectrometry.":[90],"Outcome":[91],"Arterial":[93,211],"was":[95,123,213],"assessed":[96,129,144],"carotid\u2013femoral":[98],"pulse":[99],"wave":[100],"velocity":[101],"(PWV)":[102],"augmentation":[104],"index":[105],"(Aix75).":[106],"Longitudinal":[107],"included":[109],"a":[110],"composite":[111,245,265],"major":[113],"CV":[114,249,297],"events":[115,246,298],"all-cause":[117],"mortality.":[118,300],"Analytical":[119],"Approach":[120],"categorized":[124],"into":[125],"quartiles.":[126],"Associations":[127],"were":[128,152,181,198,201],"multivariable":[131],"regression":[132,239],"adjusted":[133,270],"for":[134,263],"age,":[135],"race,":[136],"dialysis":[138],"status.":[139],"Kaplan\u2013Meier":[140,253],"Cox":[142,271],"models":[143,272],"outcomes.":[146],"Results":[147],"Among":[148],"participants,":[150],"quartiles":[151,216,262],"Q1":[153],"<":[154],"0.30":[155],"ng/mL":[156,162,168,176],"(n":[157,163,169,177],"=":[158,164,170,178],"64),":[159],"Q2":[160],"0.30\u20130.456":[161],"71),":[165],"Q3":[166],"0.457\u20130.729":[167],"68),":[171],"Q4":[173],"\u2265":[174],"0.73":[175],"67).":[179],"Strata":[180],"similar":[182,214],"age":[184],"(44.9":[185],"years),":[186],"sex,":[187],"BMI":[189],"(all":[190],"P>0.05).":[191],"Race":[192],"differed":[193],"quartile":[195],"(P<0.001);":[196],"87.4%":[197],"White.":[199],"24.8%":[200],"pre-dialytic,":[202],"61.1%":[203],"on":[204,208],"hemodialysis,":[205],"14.1%":[207],"peritoneal":[209],"dialysis.":[210],"across":[215,259],"(AIx75":[217],"\u223c20\u201321%,":[218],"P=0.99;":[219],"PWV:":[220],"7.8\u20138.0":[221],"m/s,":[222],"P=0.94).":[223],"showed":[226,273,289],"no":[227,274,290],"association":[228,292],"AIx75":[230],"PWV":[232],"before":[233],"after":[235],"adjustment":[236],"multiple":[238],"modeling.":[240],"Over":[241],"9.3":[242],"years,":[243],"115":[244],"occurred":[247],"(97":[248],"events,":[250],"18":[251],"deaths).":[252],"analysis":[254],"did":[255],"not":[256],"discriminate":[257],"risk":[258],"outcome":[266],"(log-rank":[267],"P=0.23),":[268],"association.":[275],"Limitations":[276],"Observational":[277],"design":[278],"possible":[280],"residual":[281],"confounding.":[282],"Conclusion":[283],"In":[284],"independent":[291],"Further":[301],"studies":[302],"needed":[304],"vitamin":[311],"D":[312],"patients.":[315]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-09-10T00:00:00"}
