{"id":"https://openalex.org/W7212017047","doi":"https://doi.org/10.1093/ofid/ofag558","title":"Contemporary Trends in Candidemia: Mortality, Species, and Antifungal Resistance Across Three Periods (2017\u20132025) in Houston, Texas","display_name":"Contemporary Trends in Candidemia: Mortality, Species, and Antifungal Resistance Across Three Periods (2017\u20132025) in Houston, Texas","publication_year":2026,"publication_date":"2026-09-01","ids":{"openalex":"https://openalex.org/W7212017047","doi":"https://doi.org/10.1093/ofid/ofag558","pmid":"https://pubmed.ncbi.nlm.nih.gov/42761279","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13586760"},"language":"en","primary_location":{"id":"doi:10.1093/ofid/ofag558","doi":"https://doi.org/10.1093/ofid/ofag558","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ofid/ofag558","pdf_url":null,"source":{"id":"https://openalex.org/S2735126445","display_name":"Open Forum Infectious Diseases","issn_l":"2328-8957","issn":["2328-8957"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Forum Infectious Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/ofid/ofag558","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5122757245","display_name":"Mary North Jones","orcid":"https://orcid.org/0009-0000-4028-3402","observed_orcids":["https://orcid.org/0009-0000-4028-3402"]},"institutions":[{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mary North Jones","raw_affiliation_strings":["Baylor College of Medicine Department of Medicine, , Houston, Texas ,","Division of Infectious Diseases, Department of Medicine, Houston Methodist Hospital , Houston, Texas ,"],"raw_orcid":"https://orcid.org/0009-0000-4028-3402","affiliations":[{"raw_affiliation_string":"Baylor College of Medicine Department of Medicine, , Houston, Texas ,","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"Division of Infectious Diseases, Department of Medicine, Houston Methodist Hospital , Houston, Texas ,","institution_ids":["https://openalex.org/I1295876152"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084060683","display_name":"Masayuki Nigo","orcid":"https://orcid.org/0000-0003-4898-1808","observed_orcids":["https://orcid.org/0000-0003-4898-1808"]},"institutions":[{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]},{"id":"https://openalex.org/I4405286254","display_name":"Houston Methodist Research Institute","ror":"https://ror.org/01mcrxx35","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1295876152","https://openalex.org/I4405286254"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Masayuki Nigo","raw_affiliation_strings":["Center for Infectious Diseases, Houston Methodist Research Institute , Houston, Texas ,","Department of Medicine, Weill Cornell Medical College , New York, New York ,","Division of Infectious Diseases, Department of Medicine, Houston Methodist Hospital , Houston, Texas ,"],"raw_orcid":"https://orcid.org/0000-0003-4898-1808","affiliations":[{"raw_affiliation_string":"Center for Infectious Diseases, Houston Methodist Research Institute , Houston, Texas ,","institution_ids":["https://openalex.org/I1295876152","https://openalex.org/I4405286254"]},{"raw_affiliation_string":"Department of Medicine, Weill Cornell Medical College , New York, New York ,","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Division of Infectious Diseases, Department of Medicine, Houston Methodist Hospital , Houston, Texas ,","institution_ids":["https://openalex.org/I1295876152"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103278141","display_name":"Mar\u00eda Espinosa P\u00e9rez","orcid":"https://orcid.org/0000-0002-4901-824X","observed_orcids":["https://orcid.org/0000-0002-4901-824X"]},"institutions":[{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]},{"id":"https://openalex.org/I4405286254","display_name":"Houston Methodist Research Institute","ror":"https://ror.org/01mcrxx35","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1295876152","https://openalex.org/I4405286254"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mar\u00eda Alejandra P\u00e9rez","raw_affiliation_strings":["Center for Infectious Diseases, Houston Methodist Research Institute , Houston, Texas ,"],"raw_orcid":"https://orcid.org/0000-0002-4901-824X","affiliations":[{"raw_affiliation_string":"Center for Infectious Diseases, Houston Methodist Research Institute , Houston, Texas ,","institution_ids":["https://openalex.org/I1295876152","https://openalex.org/I4405286254"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078433171","display_name":"Stefano Casarin","orcid":"https://orcid.org/0000-0002-7416-2366","observed_orcids":["https://orcid.org/0000-0002-7416-2366"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]},{"id":"https://openalex.org/I4210103659","display_name":"Laboratoire des Sciences de l'Ing\u00e9nieur pour l'Environnement","ror":"https://ror.org/01b2epx09","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210095849","https://openalex.org/I4210103659","https://openalex.org/I78744979"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]},{"id":"https://openalex.org/I4405286254","display_name":"Houston Methodist Research Institute","ror":"https://ror.org/01mcrxx35","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1295876152","https://openalex.org/I4405286254"]},{"id":"https://openalex.org/I78744979","display_name":"La Rochelle Universit\u00e9","ror":"https://ror.org/04mv1z119","country_code":"FR","type":"education","lineage":["https://openalex.org/I78744979"]}],"countries":["FR","US"],"is_corresponding":false,"raw_author_name":"Stefano Casarin","raw_affiliation_strings":["Center for Precision Surgery, Houston Methodist Research Institute , Houston, Texas ,","Department of Surgery, Weill Cornell Medical College , New York, New York ,","LaSIE, UMR 7356, CNRS, La Rochelle Universit\u00e9 , La Rochelle ,"],"raw_orcid":"https://orcid.org/0000-0002-7416-2366","affiliations":[{"raw_affiliation_string":"Center for Precision Surgery, Houston Methodist Research Institute , Houston, Texas ,","institution_ids":["https://openalex.org/I1295876152","https://openalex.org/I4405286254"]},{"raw_affiliation_string":"Department of Surgery, Weill Cornell Medical College , New York, New York ,","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"LaSIE, UMR 7356, CNRS, La Rochelle Universit\u00e9 , La Rochelle ,","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210103659","https://openalex.org/I78744979"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071199394","display_name":"Aarjav Sanghvi","orcid":"https://orcid.org/0009-0006-8107-9735","observed_orcids":["https://orcid.org/0009-0006-8107-9735"]},"institutions":[{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aarjav Sanghvi","raw_affiliation_strings":["Center for Health Data Science and Analytics, Houston Methodist Hospital , Houston, Texas ,"],"raw_orcid":"https://orcid.org/0009-0006-8107-9735","affiliations":[{"raw_affiliation_string":"Center for Health Data Science and Analytics, Houston Methodist Hospital , Houston, Texas ,","institution_ids":["https://openalex.org/I1295876152"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023875949","display_name":"Stephen L. Jones","orcid":"https://orcid.org/0000-0002-1106-171X","observed_orcids":["https://orcid.org/0000-0002-1106-171X"]},"institutions":[{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen L Jones","raw_affiliation_strings":["Center for Health Data Science and Analytics, Houston Methodist Hospital , Houston, Texas ,"],"raw_orcid":"https://orcid.org/0000-0002-1106-171X","affiliations":[{"raw_affiliation_string":"Center for Health Data Science and Analytics, Houston Methodist Hospital , Houston, Texas ,","institution_ids":["https://openalex.org/I1295876152"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077013841","display_name":"David Brian Corry","orcid":"https://orcid.org/0000-0001-9729-1016","observed_orcids":["https://orcid.org/0000-0001-9729-1016"]},"institutions":[{"id":"https://openalex.org/I1299501804","display_name":"Michael E. DeBakey VA Medical Center","ror":"https://ror.org/052qqbc08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299501804","https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210138636"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David B Corry","raw_affiliation_strings":["Department of Medicine, Baylor College of Medicine , Houston, Texas ,","Department of Pathology and Immunology, Baylor College of Medicine , Houston, Texas ,","Michael E. DeBakey Department of Veterans Affairs Medical Center, Center for Translational Research on Inflammatory Diseases (CTRID) , Houston, Texas ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Baylor College of Medicine , Houston, Texas ,","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"Department of Pathology and Immunology, Baylor College of Medicine , Houston, Texas ,","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"Michael E. DeBakey Department of Veterans Affairs Medical Center, Center for Translational Research on Inflammatory Diseases (CTRID) , Houston, Texas ,","institution_ids":["https://openalex.org/I1299501804"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027587575","display_name":"C\u00e9sar A. Arias","orcid":"https://orcid.org/0000-0001-9054-9774","observed_orcids":["https://orcid.org/0000-0001-9054-9774"]},"institutions":[{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]},{"id":"https://openalex.org/I4405286254","display_name":"Houston Methodist Research Institute","ror":"https://ror.org/01mcrxx35","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1295876152","https://openalex.org/I4405286254"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cesar A Arias","raw_affiliation_strings":["Center for Infectious Diseases, Houston Methodist Research Institute , Houston, Texas ,","Department of Medicine, Weill Cornell Medical College , New York, New York ,","Division of Infectious Diseases, Department of Medicine, Houston Methodist Hospital , Houston, Texas ,"],"raw_orcid":"https://orcid.org/0000-0001-9054-9774","affiliations":[{"raw_affiliation_string":"Center for Infectious Diseases, Houston Methodist Research Institute , Houston, Texas ,","institution_ids":["https://openalex.org/I1295876152","https://openalex.org/I4405286254"]},{"raw_affiliation_string":"Department of Medicine, Weill Cornell Medical College , New York, New York ,","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Division of Infectious Diseases, Department of Medicine, Houston Methodist Hospital , Houston, Texas ,","institution_ids":["https://openalex.org/I1295876152"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053628333","display_name":"Max W. Adelman","orcid":"https://orcid.org/0000-0002-9277-6046","observed_orcids":["https://orcid.org/0000-0002-9277-6046"]},"institutions":[{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]},{"id":"https://openalex.org/I4405286254","display_name":"Houston Methodist Research Institute","ror":"https://ror.org/01mcrxx35","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1295876152","https://openalex.org/I4405286254"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Max W Adelman","raw_affiliation_strings":["Center for Infectious Diseases, Houston Methodist Research Institute , Houston, Texas ,","Department of Medicine, Weill Cornell Medical College , New York, New York ,","Division of Infectious Diseases, Department of Medicine, Houston Methodist Hospital , Houston, Texas ,","Division of Pulmonary, Critical Care, and Sleep Medicine, Houston Methodist Hospital , Houston, Texas ,"],"raw_orcid":"https://orcid.org/0000-0002-9277-6046","affiliations":[{"raw_affiliation_string":"Center for Infectious Diseases, Houston Methodist Research Institute , Houston, Texas ,","institution_ids":["https://openalex.org/I1295876152","https://openalex.org/I4405286254"]},{"raw_affiliation_string":"Department of Medicine, Weill Cornell Medical College , New York, New York ,","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Division of Infectious Diseases, Department of Medicine, Houston Methodist Hospital , Houston, Texas ,","institution_ids":["https://openalex.org/I1295876152"]},{"raw_affiliation_string":"Division of Pulmonary, Critical Care, and Sleep Medicine, Houston Methodist Hospital , Houston, Texas ,","institution_ids":["https://openalex.org/I1295876152"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5053628333","https://openalex.org/A5122757245"],"corresponding_institution_ids":["https://openalex.org/I1295876152","https://openalex.org/I181547552","https://openalex.org/I4387153466","https://openalex.org/I4405286254"],"apc_list":{"value":4053,"currency":"USD","value_usd":4053},"apc_paid":{"value":4053,"currency":"USD","value_usd":4053},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.64281512,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"13","issue":"9","first_page":"ofag558","last_page":"ofag558"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11826","display_name":"Ocular Infections and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11037","display_name":"Fungal Infections and Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/candidemia","display_name":"candidemia","score":0.9919999837875366},{"id":"https://openalex.org/keywords/candidemia-mortality","display_name":"candidemia mortality","score":0.8019999861717224},{"id":"https://openalex.org/keywords/candida-auris","display_name":"Candida auris","score":0.8809999823570251},{"id":"https://openalex.org/keywords/antifungal-resistance","display_name":"antifungal resistance","score":0.9549999833106995},{"id":"https://openalex.org/keywords/candida-species-distribution","display_name":"Candida species distribution","score":0.8960000276565552},{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.6869999766349792},{"id":"https://openalex.org/keywords/staphylococcus-aureus-bacteremia","display_name":"Staphylococcus aureus bacteremia","score":0.8679999709129333},{"id":"https://openalex.org/keywords/comorbidity","display_name":"comorbidities","score":0.5830000042915344},{"id":"https://openalex.org/keywords/age","display_name":"age","score":0.31299999356269836},{"id":"https://openalex.org/keywords/houston","display_name":"Houston","score":0.7839999794960022},{"id":"https://openalex.org/keywords/temporal-trends","display_name":"temporal trends","score":0.6980000138282776},{"id":"https://openalex.org/keywords/30-day-mortality","display_name":"30-day mortality","score":0.6520000100135803},{"id":"https://openalex.org/keywords/risk-factors-for-mortality","display_name":"mortality risk factors","score":0.46399998664855957},{"id":"https://openalex.org/keywords/antifungal-susceptibility-testing","display_name":"antifungal susceptibility testing","score":0.453000009059906}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8657000064849854},{"id":"https://openalex.org/C2779443120","wikidata":"https://www.wikidata.org/wiki/Q650912","display_name":"Bacteremia","level":3,"score":0.6225000023841858},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.510699987411499},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.48330000042915344},{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.46970000863075256},{"id":"https://openalex.org/C2779548794","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal","level":2,"score":0.46470001339912415},{"id":"https://openalex.org/C114851261","wikidata":"https://www.wikidata.org/wiki/Q12147416","display_name":"Drug resistance","level":2,"score":0.45910000801086426},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4442000091075897},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.4059000015258789},{"id":"https://openalex.org/C2909786013","wikidata":"https://www.wikidata.org/wiki/Q26816853","display_name":"Candida auris","level":3,"score":0.3926999866962433},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.38530001044273376},{"id":"https://openalex.org/C2780558435","wikidata":"https://www.wikidata.org/wiki/Q3491700","display_name":"Fungemia","level":3,"score":0.38179999589920044},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.3199000060558319},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.31700000166893005},{"id":"https://openalex.org/C3018946976","wikidata":"https://www.wikidata.org/wiki/Q650912","display_name":"Bloodstream infection","level":2,"score":0.27889999747276306},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.27070000767707825},{"id":"https://openalex.org/C2777334864","wikidata":"https://www.wikidata.org/wiki/Q34879","display_name":"Staphylococcal infections","level":4,"score":0.2660999894142151},{"id":"https://openalex.org/C2780690907","wikidata":"https://www.wikidata.org/wiki/Q412236","display_name":"Voriconazole","level":3,"score":0.26409998536109924},{"id":"https://openalex.org/C2777984932","wikidata":"https://www.wikidata.org/wiki/Q7336293","display_name":"Risk of mortality","level":2,"score":0.2639999985694885},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.2549999952316284},{"id":"https://openalex.org/C2780908437","wikidata":"https://www.wikidata.org/wiki/Q464067","display_name":"Mycosis","level":2,"score":0.25220000743865967},{"id":"https://openalex.org/C2777052132","wikidata":"https://www.wikidata.org/wiki/Q595158","display_name":"Methicillin-resistant Staphylococcus aureus","level":4,"score":0.2506999969482422}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1093/ofid/ofag558","doi":"https://doi.org/10.1093/ofid/ofag558","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ofid/ofag558","pdf_url":null,"source":{"id":"https://openalex.org/S2735126445","display_name":"Open Forum Infectious Diseases","issn_l":"2328-8957","issn":["2328-8957"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Forum Infectious Diseases","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13586760","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13586760/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13586760/pdf/ofag558.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Forum Infect Dis","raw_type":"Text"},{"id":"pmid:42761279","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42761279","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open forum infectious diseases","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1093/ofid/ofag558","doi":"https://doi.org/10.1093/ofid/ofag558","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ofid/ofag558","pdf_url":null,"source":{"id":"https://openalex.org/S2735126445","display_name":"Open Forum Infectious Diseases","issn_l":"2328-8957","issn":["2328-8957"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Forum Infectious Diseases","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1657461745","display_name":null,"funder_award_id":"23550001","funder_id":"https://openalex.org/F4320333841","funder_display_name":"Houston Methodist Research Institute"},{"id":"https://openalex.org/G9000891387","display_name":"Pathogen and patient determinants of Candida gut colonization in critically ill patients","funder_award_id":"K23AI185174","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320333841","display_name":"Houston Methodist Research Institute","ror":null},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7212017047.pdf","grobid_xml":"https://content.openalex.org/works/W7212017047.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W2044502735","https://openalex.org/W2045030413","https://openalex.org/W2057780602","https://openalex.org/W2069172362","https://openalex.org/W2216117396","https://openalex.org/W2280404143","https://openalex.org/W2547589532","https://openalex.org/W2922388167","https://openalex.org/W2964743581","https://openalex.org/W3003483284","https://openalex.org/W3049534229","https://openalex.org/W3128848972","https://openalex.org/W3188716630","https://openalex.org/W3199320884","https://openalex.org/W3202473737","https://openalex.org/W4210336770","https://openalex.org/W4281789383","https://openalex.org/W4293511012","https://openalex.org/W4300690590","https://openalex.org/W4308458455","https://openalex.org/W4309073127","https://openalex.org/W4320896711","https://openalex.org/W4327912896","https://openalex.org/W4387167915","https://openalex.org/W4392376605","https://openalex.org/W4400803638","https://openalex.org/W4402485864","https://openalex.org/W4404557738","https://openalex.org/W4405529762","https://openalex.org/W4406404289","https://openalex.org/W4407235545","https://openalex.org/W4410381673","https://openalex.org/W4410775086","https://openalex.org/W4415225119","https://openalex.org/W4416364535","https://openalex.org/W7124891530","https://openalex.org/W7154110100","https://openalex.org/W7160928253"],"related_works":["https://openalex.org/W7163743411","https://openalex.org/W4406943225","https://openalex.org/W7160928253","https://openalex.org/W7122576484","https://openalex.org/W7172336509","https://openalex.org/W4393860394","https://openalex.org/W4407260378","https://openalex.org/W4403837725","https://openalex.org/W4401283283","https://openalex.org/W7047885355"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Candida":[2],"species":[3,256],"distribution":[4],"has":[5,10],"changed":[6],"and":[7,43,52,55,89,120,154,216,233,253],"antifungal":[8,234],"resistance":[9,44,235,258],"increased":[11,78,105,169,181,196,226,240],"since":[12],"COVID-19.":[13],"We":[14,60],"determined":[15],"whether":[16],"these":[17],"trends":[18],"contributed":[19],"to":[20,58,81,108,132,172,184,199],"changes":[21,252],"in":[22,35,64,93,110,134,248,265],"candidemia":[23,34,65,73,175,180,218],"mortality.":[24,59,227,241],"Methods":[25],"In":[26,101,207,228],"a":[27],"retrospective":[28],"cohort":[29],"study":[30],"of":[31,178,193],"patients":[32,71,111],"with":[33,72,112,225,239,250,255],"Houston,":[36],"TX,":[37],"we":[38],"compared":[39,61],"clinical":[40],"characteristics,":[41],"species,":[42],"between":[45],"3":[46],"periods":[47],"(P1,":[48],"2017\u20132019;":[49],"P2,":[50],"2020\u20132022;":[51],"P3,":[53],"2023\u20132025)":[54],"assessed":[56],"contribution":[57],"30-day":[62,76,103],"mortality":[63,77,104,245,267],"versus":[66],"bacteremia.":[67],"Results":[68],"Among":[69],"1275":[70],"(1386":[74],"episodes),":[75],"from":[79,106,170,182,197],"P1":[80,107,171,183,198],"P2":[82,109,185],"(19.7%":[83],"vs":[84,99,115,125,140,147,162,187,202],"31.9%,":[85],"P":[86,96,117,127,137,151,166,189,204],"<":[87,97,128,167,205],".001)":[88,129,168],"remained":[90],"above":[91],"baseline":[92,133],"P3":[94,135,173,200],"(29.8%,":[95],".001":[98],"P1).":[100,141],"contrast,":[102],"Enterobacterales":[113],"(7.4%":[114],"9.5%,":[116],"=":[118,152,190],".004)":[119],"Staphylococcus":[121],"aureus":[122],"bacteremia":[123],"(9.5%":[124],"14.3%,":[126],"but":[130],"returned":[131],"(both":[136],">":[138],".05":[139],"Mean":[142],"age":[143,210],"(62.7":[144],"\u00b1":[145,149],"16.0":[146],"66.1":[148],"14.8,":[150],".002)":[153],"median":[155],"Elixhauser":[156],"Comorbidity":[157],"Index":[158],"(8":[159],"[IQR":[160,164],"5\u201312]":[161],"11":[163],"6\u201315],":[165],"among":[174],"patients.":[176],"Proportion":[177,192],"ICU-onset":[179,217],"(31.3%":[186],"40.6%,":[188],".02).":[191],"C.":[194,231],"auris":[195,232],"(0.5%":[201],"20.5%,":[203],".001).":[206],"multivariable":[208],"analyses,":[209,230],"(OR":[211,219],"1.03,":[212],"95%":[213],"CI":[214],"1.02\u20131.04)":[215],"2.08,":[220],"95%CI":[221],"1.46\u20132.98)":[222],"were":[223,236],"associated":[224,238,247],"univariable":[229],"not":[237,254],"Conclusions":[242],"Increased":[243],"post-candidemia":[244,266],"was":[246],"part":[249],"demographic":[251],"or":[257],"changes.":[259],"Factors":[260],"underlying":[261],"the":[262],"persistent":[263],"increase":[264],"are":[268],"unclear.":[269]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-09-10T00:00:00"}