{"id":"https://openalex.org/W7211875058","doi":"https://doi.org/10.5281/zenodo.22639970","title":"SEM to Simulation: Bringing Ultrastructural Detail to Multiscale Modeling","display_name":"SEM to Simulation: Bringing Ultrastructural Detail to Multiscale Modeling","publication_year":2026,"publication_date":"2026-09-07","ids":{"openalex":"https://openalex.org/W7211875058","doi":"https://doi.org/10.5281/zenodo.22639970"},"language":"en","primary_location":{"id":"doi:10.5281/zenodo.22639970","doi":"https://doi.org/10.5281/zenodo.22639970","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.22639970","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"ConferencePaper"},"volume":null,"type":"conference-paper","is_traditional":true,"indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.5281/zenodo.22639970","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075673021","display_name":"Cecilia Romaro","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Romaro, Cecilia","raw_affiliation_strings":["Department of Biostatistics, Yale School of Public Health, New Haven, CT, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, Yale School of Public Health, New Haven, CT, United States","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5140589036","display_name":"Matei-Victor Coldea","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Coldea, Matei","raw_affiliation_strings":["Yale College, Yale University, New Haven, CT, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yale College, Yale University, New Haven, CT, United States","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082122443","display_name":"William W. Lytton","orcid":"https://orcid.org/0000-0002-3727-2849","observed_orcids":["https://orcid.org/0000-0002-3727-2849"]},"institutions":[{"id":"https://openalex.org/I181697535","display_name":"SUNY Downstate Health Sciences University","ror":"https://ror.org/0041qmd21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I181697535"]},{"id":"https://openalex.org/I4210117211","display_name":"Kings County Hospital Center","ror":"https://ror.org/02emy8e21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1283621791","https://openalex.org/I4210117211"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lytton, William W.","raw_affiliation_strings":["Department of Physiology and Pharmacology & Neurology, SUNY Downstate Health Sciences University, Brooklyn, New York; Department of Neurology, Kings County Hospital Center, Brooklyn, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Pharmacology & Neurology, SUNY Downstate Health Sciences University, Brooklyn, New York; Department of Neurology, Kings County Hospital Center, Brooklyn, New York","institution_ids":["https://openalex.org/I181697535","https://openalex.org/I4210117211"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025235631","display_name":"Robert A. McDougal","orcid":"https://orcid.org/0000-0001-6394-3127","observed_orcids":["https://orcid.org/0000-0001-6394-3127"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"McDougal, Robert A.","raw_affiliation_strings":["Department of Biostatistics, Yale School of Public Health, New Haven, CT, United States; Department of Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, CT, United States; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, United States; Wu Tsai Institute, Yale University, New Haven, CT, United States; Interdepartmental Neuroscience Program, Yale University, New Haven, CT, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, Yale School of Public Health, New Haven, CT, United States; Department of Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, CT, United States; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, United States; Wu Tsai Institute, Yale University, New Haven, CT, United States; Interdepartmental Neuroscience Program, Yale University, New Haven, CT, United States","institution_ids":["https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.65197074,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.823199987411499,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.823199987411499,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.08299999684095383,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14411","display_name":"Undergraduate Neuroscience Education and Research","score":0.030799999833106995,"subfield":{"id":"https://openalex.org/subfields/3304","display_name":"Education"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/spine-morphology","display_name":"dendritic spine morphology","score":0.4880000054836273},{"id":"https://openalex.org/keywords/scanning-electron-microscopy","display_name":"scanning electron microscopy","score":0.5659999847412109},{"id":"https://openalex.org/keywords/multiscale-modeling","display_name":"multiscale modeling","score":0.6600000262260437},{"id":"https://openalex.org/keywords/neuron-simulator","display_name":"NEURON simulator","score":0.9100000262260437},{"id":"https://openalex.org/keywords/dendritic-ultrastructure","display_name":"dendritic ultrastructure","score":0.6420000195503235},{"id":"https://openalex.org/keywords/ip3-receptor","display_name":"IP3 receptor","score":0.3930000066757202},{"id":"https://openalex.org/keywords/calcium-signaling","display_name":"calcium signaling","score":0.4740000069141388},{"id":"https://openalex.org/keywords/3d-spine-reconstruction","display_name":"3D spine reconstruction","score":0.5410000085830688},{"id":"https://openalex.org/keywords/graphical-user-interface","display_name":"graphical user interface","score":0.5429999828338623},{"id":"https://openalex.org/keywords/synaptic-plasticity","display_name":"synaptic plasticity","score":0.734000027179718},{"id":"https://openalex.org/keywords/pyside6","display_name":"PySide6","score":0.4779999852180481}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6705999970436096},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.6119999885559082},{"id":"https://openalex.org/C37789001","wikidata":"https://www.wikidata.org/wiki/Q782543","display_name":"Graphical user interface","level":2,"score":0.5335999727249146},{"id":"https://openalex.org/C153083717","wikidata":"https://www.wikidata.org/wiki/Q6535263","display_name":"Leverage (statistics)","level":2,"score":0.5322999954223633},{"id":"https://openalex.org/C174884520","wikidata":"https://www.wikidata.org/wiki/Q902079","display_name":"Dendritic spine","level":3,"score":0.5250999927520752},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.47519999742507935},{"id":"https://openalex.org/C54170458","wikidata":"https://www.wikidata.org/wiki/Q663554","display_name":"Voxel","level":2,"score":0.4717000126838684},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.4648999869823456},{"id":"https://openalex.org/C2779097318","wikidata":"https://www.wikidata.org/wiki/Q2993446","display_name":"Connectomics","level":4,"score":0.4562999904155731},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.44699999690055847},{"id":"https://openalex.org/C205383261","wikidata":"https://www.wikidata.org/wiki/Q7392570","display_name":"SPINE (molecular biology)","level":2,"score":0.42570000886917114},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.41609999537467957},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.39660000801086426},{"id":"https://openalex.org/C113843644","wikidata":"https://www.wikidata.org/wiki/Q901882","display_name":"Interface (matter)","level":4,"score":0.39250001311302185},{"id":"https://openalex.org/C62354387","wikidata":"https://www.wikidata.org/wiki/Q875399","display_name":"Boundary (topology)","level":2,"score":0.37400001287460327},{"id":"https://openalex.org/C121684516","wikidata":"https://www.wikidata.org/wiki/Q7600677","display_name":"Computer graphics (images)","level":1,"score":0.37299999594688416},{"id":"https://openalex.org/C104122410","wikidata":"https://www.wikidata.org/wiki/Q1416406","display_name":"Network model","level":2,"score":0.3693000078201294},{"id":"https://openalex.org/C141123601","wikidata":"https://www.wikidata.org/wiki/Q6935072","display_name":"Multiscale modeling","level":2,"score":0.351500004529953},{"id":"https://openalex.org/C147080431","wikidata":"https://www.wikidata.org/wiki/Q1074953","display_name":"Microscopy","level":2,"score":0.334199994802475},{"id":"https://openalex.org/C109950114","wikidata":"https://www.wikidata.org/wiki/Q4464732","display_name":"3D reconstruction","level":2,"score":0.33070001006126404},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.29679998755455017},{"id":"https://openalex.org/C9395851","wikidata":"https://www.wikidata.org/wiki/Q177929","display_name":"Stack (abstract data type)","level":2,"score":0.29660001397132874},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.2782999873161316},{"id":"https://openalex.org/C459310","wikidata":"https://www.wikidata.org/wiki/Q117801","display_name":"Computational science","level":1,"score":0.271699994802475},{"id":"https://openalex.org/C44154836","wikidata":"https://www.wikidata.org/wiki/Q45045","display_name":"Simulation","level":1,"score":0.2703999876976013},{"id":"https://openalex.org/C499950583","wikidata":"https://www.wikidata.org/wiki/Q183252","display_name":"Morphology (biology)","level":2,"score":0.26989999413490295},{"id":"https://openalex.org/C26517878","wikidata":"https://www.wikidata.org/wiki/Q228039","display_name":"Key (lock)","level":2,"score":0.2669999897480011},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.26339998841285706},{"id":"https://openalex.org/C172367668","wikidata":"https://www.wikidata.org/wiki/Q6504956","display_name":"Data visualization","level":3,"score":0.26249998807907104},{"id":"https://openalex.org/C102951782","wikidata":"https://www.wikidata.org/wiki/Q49295","display_name":"Atomic force microscopy","level":2,"score":0.25780001282691956},{"id":"https://openalex.org/C185877587","wikidata":"https://www.wikidata.org/wiki/Q1757407","display_name":"Medial axis","level":2,"score":0.25780001282691956},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.2572000026702881},{"id":"https://openalex.org/C2777897806","wikidata":"https://www.wikidata.org/wiki/Q568742","display_name":"3D modeling","level":2,"score":0.2549999952316284},{"id":"https://openalex.org/C9417928","wikidata":"https://www.wikidata.org/wiki/Q1070689","display_name":"Image processing","level":3,"score":0.2549000084400177},{"id":"https://openalex.org/C26771246","wikidata":"https://www.wikidata.org/wiki/Q321095","display_name":"Scanning electron microscope","level":2,"score":0.25220000743865967},{"id":"https://openalex.org/C141379421","wikidata":"https://www.wikidata.org/wiki/Q6094427","display_name":"Iterative reconstruction","level":2,"score":0.2515999972820282}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.5281/zenodo.22639970","doi":"https://doi.org/10.5281/zenodo.22639970","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.22639970","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"ConferencePaper"},{"id":"doi:10.5281/zenodo.22639971","doi":"https://doi.org/10.5281/zenodo.22639971","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.22639971","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"ConferencePaper"}],"best_oa_location":{"id":"doi:10.5281/zenodo.22639970","doi":"https://doi.org/10.5281/zenodo.22639970","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.22639970","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"ConferencePaper"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2083877563","https://openalex.org/W4405108791","https://openalex.org/W2139833624","https://openalex.org/W2327793798","https://openalex.org/W2007337197","https://openalex.org/W2014959051","https://openalex.org/W3004825607","https://openalex.org/W167284886","https://openalex.org/W1557544222","https://openalex.org/W2079709452"],"abstract_inverted_index":{"Introduction":[0],"Just":[1],"as":[2,337],"neuron":[3,43],"morphology":[4,44],"influences":[5],"spiking":[6],"behavior":[7,377],"and":[8,25,45,75,90,138,147,178,222,236,279,289,347,387,401,449],"thus":[9,26],"network":[10,388],"interactions,":[11],"so":[12,155],"too":[13],"does":[14,450],"the":[15,37,69,144,149,160,194,232,237,268,298,314,317,413,426,444,447,454,458,482],"3D":[16,261,277],"placement":[17],"of":[18,80,83,218,230,253,316,334,352,409,415,429,434,446,457,461,485],"spines":[19,23,174,198,239],"affect":[20],"interaction":[21],"between":[22,297],"[1]":[24,464],"cellular":[27],"behavior.":[28],"However":[29],"fine":[30],"spine":[31,117,195,305],"details":[32,398],"are":[33,52,362],"not":[34,54,341,451],"visible":[35],"under":[36],"optical":[38],"microscopy":[39,49],"used":[40,167,329],"for":[41,68,73,97,103,205,303,330,366,478],"reconstructing":[42],"full-cell":[46,95],"scanning":[47],"electron":[48],"(SEM)":[50],"images":[51,110],"generally":[53],"feasible":[55,342],"due":[56],"to":[57,114,124,168,175,192,202,255,273,282,312,343,374,404],"size":[58],"constraints.":[59],"To":[60],"address":[61],"these":[62],"challenges,":[63],"we":[64,157],"developed":[65],"a":[66,81,84,94,125,170,249,259,264,274,309,335,381],"tool":[67,142,227,294,322,391],"NEURON":[70,308,500],"simulator":[71],"[2]":[72],"importing":[74],"editing":[76],"an":[77],"SEM":[78,109,234,332],"reconstruction":[79,96],"portion":[82],"dendrite,":[85],"selecting":[86],"spines,":[87],"rotating":[88],"them,":[89],"inserting":[91],"them":[92],"into":[93,180],"simulation,":[98],"using":[99,118],"our":[100,214,245,293,370],"experimental":[101],"support":[102],"reaction-diffusion":[104],"multigridding":[105],"in":[106,378,380,418],"NEURON.":[107],"Methods":[108],"may":[111],"be":[112,176,185,200,256,328],"segmented":[113],"identify":[115],"each":[116,152],"standard":[119],"segmentation":[120],"software":[121],"then":[122],"exported":[123,201],"TIFF":[126],"stack.":[127],"We":[128,212,266],"estimate":[129],"key":[130],"electrical":[131],"properties:":[132],"approximately":[133],"equivalent":[134],"length,":[135],"diameter,":[136],"volume,":[137],"surface":[139],"area.":[140],"Our":[141],"loads":[143],"image":[145],"stack":[146],"identifies":[148],"voxels":[150,191],"forming":[151],"spine-dendrite":[153],"boundary":[154],"that":[156,356],"can":[158,183,199,325,392],"preserve":[159],"connection":[161],"location":[162,262],"after":[163,240],"transformations.":[164,241],"PySide6":[165],"is":[166,340,355,442],"provide":[169],"graphical":[171,215,226],"interface":[172],"allowing":[173,248],"selected":[177],"manipulated":[179],"position;":[181],"this":[182,350],"also":[184,326],"done":[186],"programmatically.":[187],"An":[188],"algorithm":[189],"adds/removes":[190],"connect":[193],"cleanly.":[196],"Transformed":[197],"text":[203],"files":[204],"easy":[206],"editing,":[207],"enabling":[208],"iterative":[209],"refinement.":[210],"Results":[211],"present":[213],"tool,":[216],"examples":[217],"relevant":[219],"data":[220,235,333],"sets,":[221],"simulation":[223,270,278],"results.":[224],"The":[225,242,320,440,499],"allows":[228,295,372],"visualization":[229],"both":[231],"loaded":[233],"placed":[238,257],"simulations":[243],"leverage":[244],"previous":[246],"work,":[247],"synaptic":[250,410],"source":[251],"(e.g.,":[252],"IP3)":[254],"at":[258,349],"precise":[260],"within":[263],"spine.":[265],"validate":[267],"multigrid":[269],"by":[271,425],"comparing":[272],"single":[275],"unified":[276],"contrast":[280],"it":[281],"simplified":[283],"geometry":[284],"approximations,":[285],"illustrating":[286],"their":[287],"similarities":[288],"differences.":[290],"In":[291],"particular,":[292],"toggling":[296],"two":[299],"representations.":[300],"Discussion":[301],"Support":[302],"imported":[304],"morphologies":[306],"brings":[307],"step":[310],"closer":[311],"capturing":[313],"intricacies":[315],"human":[318],"brain.":[319],"same":[321],"described":[323],"here":[324],"directly":[327],"incorporating":[331],"dendrite":[336],"well.":[338],"It":[339],"simulate":[344],"full":[345,385],"cells":[346],"networks":[348],"level":[351],"detail,":[353],"nor":[354],"necessarily":[357,452],"desirable":[358],"--":[359,368],"simpler":[360],"models":[361],"often":[363],"more":[364],"useful":[365],"insights":[367],"but":[369],"approach":[371],"us":[373,394,403],"explore":[375,405],"localized":[376],"detail":[379],"multiscale":[382],"context":[383],"with":[384],"cell":[386],"simulations.":[389],"This":[390,421],"give":[393],"insight":[395],"on":[396],"which":[397],"model":[399],"when":[400],"allow":[402],"detailed":[406],"biological":[407],"questions":[408],"plasticity":[411],"or":[412],"role":[414],"morphological":[416],"changes":[417],"disease.":[419],"Acknowledgments":[420],"research":[422],"was":[423],"funded":[424],"National":[427,432,459],"Institute":[428],"Mental":[430],"Health,":[431,435],"Institutes":[433,460],"grant":[436],"number":[437],"R01":[438],"MH086638.":[439],"content":[441],"solely":[443],"responsibility":[445],"authors":[448],"represent":[453],"official":[455],"views":[456],"Health.":[462],"References":[463],"Huertas,":[465],"M.,":[466],"Newton,":[467],"A.,":[468],"McDougal,":[469],"R.,":[470],"Sacktor,":[471],"T.,":[472],"&":[473,495],"Shouval,":[474],"H.":[475],"(2022).":[476],"Conditions":[477],"Synaptic":[479,486],"Specificity":[480],"during":[481],"Maintenance":[483],"Phase":[484],"Plasticity.":[487],"eneuro,":[488],"9(3),":[489],"ENEURO.0064-22.2022.":[490],"doi:":[491,507],"10.1523/ENEURO.0064-22.2022[2]":[492],"Hines,":[493],"M.":[494],"Carnevale,":[496],"N.":[497],"(1997).":[498],"Simulation":[501],"Environment.":[502],"Neural":[503],"Computation,":[504],"9(6),":[505],"1179-1209.":[506],"10.1162/neco.1997.9.6.1179":[508]},"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2026-09-08T00:00:00"}