{"id":"https://openalex.org/W7208826634","doi":"https://doi.org/10.1007/s12247-026-11021-y","title":"3D-Printed Multicompartmental Microneedles for Chronopharmacology-based Polytherapy","display_name":"3D-Printed Multicompartmental Microneedles for Chronopharmacology-based Polytherapy","publication_year":2026,"publication_date":"2026-09-05","ids":{"openalex":"https://openalex.org/W7208826634","doi":"https://doi.org/10.1007/s12247-026-11021-y"},"language":"en","primary_location":{"id":"doi:10.1007/s12247-026-11021-y","doi":"https://doi.org/10.1007/s12247-026-11021-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s12247-026-11021-y","pdf_url":null,"source":{"id":"https://openalex.org/S168111969","display_name":"Journal of Pharmaceutical Innovation","issn_l":"1872-5120","issn":["1872-5120","1939-8042"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical Innovation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5138369150","display_name":"Akash Ganjam Ramesha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285236","display_name":"Adichunchanagiri University","ror":"https://ror.org/051n8fq88","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405285236"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Akash Ganjam Ramesha","raw_affiliation_strings":["Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya, Karnataka, 571448, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya, Karnataka, 571448, India","institution_ids":["https://openalex.org/I4405285236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036407280","display_name":"Kiran Kumar G B","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285236","display_name":"Adichunchanagiri University","ror":"https://ror.org/051n8fq88","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405285236"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Kiran Kumar Gubbi Basavaraju","raw_affiliation_strings":["Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya, Karnataka, 571448, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya, Karnataka, 571448, India","institution_ids":["https://openalex.org/I4405285236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108403844","display_name":"Prasiddhi Naik","orcid":"https://orcid.org/0009-0000-8046-2990","observed_orcids":["https://orcid.org/0009-0000-8046-2990"]},"institutions":[{"id":"https://openalex.org/I4405285236","display_name":"Adichunchanagiri University","ror":"https://ror.org/051n8fq88","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405285236"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Prasiddhi Naik","raw_affiliation_strings":["Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya, Karnataka, 571448, India"],"raw_orcid":"https://orcid.org/0009-0000-8046-2990","affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya, Karnataka, 571448, India","institution_ids":["https://openalex.org/I4405285236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138343313","display_name":"Bharath Gowda Kunigal Somashekhar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285236","display_name":"Adichunchanagiri University","ror":"https://ror.org/051n8fq88","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405285236"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Bharath Gowda Kunigal Somashekhar","raw_affiliation_strings":["Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya, Karnataka, 571448, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya, Karnataka, 571448, India","institution_ids":["https://openalex.org/I4405285236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5150076679","display_name":"Usha Chikkahonnne Gowdanapalya Gangadharaiah","orcid":"https://orcid.org/0009-0009-5972-4373","observed_orcids":["https://orcid.org/0009-0009-5972-4373"]},"institutions":[{"id":"https://openalex.org/I4405285236","display_name":"Adichunchanagiri University","ror":"https://ror.org/051n8fq88","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405285236"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Usha Chikkahonnne Gowdanapalya Gangadharaiah","raw_affiliation_strings":["Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya, Karnataka, 571448, India"],"raw_orcid":"https://orcid.org/0009-0009-5972-4373","affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya, Karnataka, 571448, India","institution_ids":["https://openalex.org/I4405285236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5150261840","display_name":"Suhas Gowda Premkumar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285236","display_name":"Adichunchanagiri University","ror":"https://ror.org/051n8fq88","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405285236"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Suhas Gowda Premkumar","raw_affiliation_strings":["Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya, Karnataka, 571448, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya, Karnataka, 571448, India","institution_ids":["https://openalex.org/I4405285236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138289577","display_name":"Surabhi Nagarajnaik","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285236","display_name":"Adichunchanagiri University","ror":"https://ror.org/051n8fq88","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405285236"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Surabhi Nagarajnaik","raw_affiliation_strings":["Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya, Karnataka, 571448, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya, Karnataka, 571448, India","institution_ids":["https://openalex.org/I4405285236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124702324","display_name":"Yashwanth Sriramareddy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285236","display_name":"Adichunchanagiri University","ror":"https://ror.org/051n8fq88","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405285236"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Yashwanth Sriramareddy","raw_affiliation_strings":["Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya, Karnataka, 571448, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya, Karnataka, 571448, India","institution_ids":["https://openalex.org/I4405285236"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5138324161","display_name":"Shashank Gangiah","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285236","display_name":"Adichunchanagiri University","ror":"https://ror.org/051n8fq88","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405285236"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Shashank Gangiah","raw_affiliation_strings":["Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya, Karnataka, 571448, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G. Nagara, Mandya, Karnataka, 571448, India","institution_ids":["https://openalex.org/I4405285236"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5108403844"],"corresponding_institution_ids":["https://openalex.org/I4405285236"],"apc_list":{"value":3990,"currency":"USD","value_usd":3990},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"22","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/3d-printed-microneedles","display_name":"3D-printed microneedles","score":0.9599999785423279},{"id":"https://openalex.org/keywords/chronopharmacology","display_name":"chronopharmacology","score":0.9610000252723694},{"id":"https://openalex.org/keywords/chronotherapy","display_name":"chronotherapy","score":0.9599999785423279},{"id":"https://openalex.org/keywords/polypharmacy","display_name":"polypharmacy","score":0.9570000171661377},{"id":"https://openalex.org/keywords/transdermal-drug-delivery","display_name":"transdermal drug delivery","score":0.9480000138282776},{"id":"https://openalex.org/keywords/stereolithography","display_name":"stereolithography","score":0.8149999976158142},{"id":"https://openalex.org/keywords/digital-light-processing","display_name":"digital light processing","score":0.921999990940094},{"id":"https://openalex.org/keywords/fused-deposition-modeling","display_name":"fused deposition modeling","score":0.9890000224113464},{"id":"https://openalex.org/keywords/print-resolution","display_name":"printing resolution","score":0.609000027179718},{"id":"https://openalex.org/keywords/sustained-release","display_name":"sustained drug release","score":0.5149999856948853},{"id":"https://openalex.org/keywords/stimuli-responsive-release","display_name":"stimuli-responsive release","score":0.7760000228881836},{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"rheumatoid arthritis","score":0.8270000219345093},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.9200000166893005},{"id":"https://openalex.org/keywords/epilepsy","display_name":"epilepsy","score":0.9950000047683716},{"id":"https://openalex.org/keywords/cancer","display_name":"cancer","score":0.699999988079071},{"id":"https://openalex.org/keywords/personalized-medicine","display_name":"personalized medicine","score":0.8069999814033508}],"concepts":[{"id":"https://openalex.org/C205679159","wikidata":"https://www.wikidata.org/wiki/Q3375179","display_name":"Transdermal","level":2,"score":0.7709000110626221},{"id":"https://openalex.org/C2779910239","wikidata":"https://www.wikidata.org/wiki/Q7539765","display_name":"Chronotherapy (sleep phase)","level":3,"score":0.6970999836921692},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4799000024795532},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.4507000148296356},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.44020000100135803},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.38280001282691956},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3474000096321106},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3366999924182892},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3095000088214874},{"id":"https://openalex.org/C2779652045","wikidata":"https://www.wikidata.org/wiki/Q507443","display_name":"Pharmaceutical industry","level":2,"score":0.2964000105857849},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.29280000925064087},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.2768999934196472},{"id":"https://openalex.org/C2781047461","wikidata":"https://www.wikidata.org/wiki/Q679692","display_name":"Biopharmaceutical","level":2,"score":0.26669999957084656},{"id":"https://openalex.org/C2777093003","wikidata":"https://www.wikidata.org/wiki/Q6508345","display_name":"Lead (geology)","level":2,"score":0.25699999928474426}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/s12247-026-11021-y","doi":"https://doi.org/10.1007/s12247-026-11021-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s12247-026-11021-y","pdf_url":null,"source":{"id":"https://openalex.org/S168111969","display_name":"Journal of Pharmaceutical Innovation","issn_l":"1872-5120","issn":["1872-5120","1939-8042"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical Innovation","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":116,"referenced_works":["https://openalex.org/W2513356353","https://openalex.org/W2517604419","https://openalex.org/W2768889320","https://openalex.org/W2917743440","https://openalex.org/W2921914754","https://openalex.org/W2936156980","https://openalex.org/W2979604112","https://openalex.org/W2982261014","https://openalex.org/W3006266588","https://openalex.org/W3007972422","https://openalex.org/W3017037896","https://openalex.org/W3023960002","https://openalex.org/W3035844765","https://openalex.org/W3039924081","https://openalex.org/W3046677160","https://openalex.org/W3082455013","https://openalex.org/W3091111273","https://openalex.org/W3092293729","https://openalex.org/W3095245663","https://openalex.org/W3107004221","https://openalex.org/W3108947319","https://openalex.org/W3114219921","https://openalex.org/W3116236574","https://openalex.org/W3122121079","https://openalex.org/W3128895153","https://openalex.org/W3130982306","https://openalex.org/W3141017926","https://openalex.org/W3154545544","https://openalex.org/W3158604297","https://openalex.org/W3161581468","https://openalex.org/W3185052035","https://openalex.org/W3186409786","https://openalex.org/W3188397970","https://openalex.org/W3194059104","https://openalex.org/W3208163174","https://openalex.org/W3210583742","https://openalex.org/W4200057544","https://openalex.org/W4200498211","https://openalex.org/W4214573087","https://openalex.org/W4220734016","https://openalex.org/W4220795894","https://openalex.org/W4220970886","https://openalex.org/W4250911711","https://openalex.org/W4281251874","https://openalex.org/W4286214550","https://openalex.org/W4287511627","https://openalex.org/W4297102728","https://openalex.org/W4306403537","https://openalex.org/W4307944276","https://openalex.org/W4309791409","https://openalex.org/W4311098611","https://openalex.org/W4318205368","https://openalex.org/W4319311008","https://openalex.org/W4319317472","https://openalex.org/W4323847885","https://openalex.org/W4360982767","https://openalex.org/W4366425777","https://openalex.org/W4367317721","https://openalex.org/W4375841897","https://openalex.org/W4378471342","https://openalex.org/W4385754847","https://openalex.org/W4386028989","https://openalex.org/W4387363233","https://openalex.org/W4387502146","https://openalex.org/W4387591797","https://openalex.org/W4388098916","https://openalex.org/W4388288918","https://openalex.org/W4388687084","https://openalex.org/W4391263011","https://openalex.org/W4391575950","https://openalex.org/W4392519216","https://openalex.org/W4394064233","https://openalex.org/W4396779231","https://openalex.org/W4396923580","https://openalex.org/W4399701753","https://openalex.org/W4400033051","https://openalex.org/W4400610065","https://openalex.org/W4401327718","https://openalex.org/W4401856310","https://openalex.org/W4402198331","https://openalex.org/W4402378766","https://openalex.org/W4402445507","https://openalex.org/W4402663827","https://openalex.org/W4402692700","https://openalex.org/W4403064290","https://openalex.org/W4403250654","https://openalex.org/W4403826878","https://openalex.org/W4403899779","https://openalex.org/W4404138595","https://openalex.org/W4404140187","https://openalex.org/W4404536097","https://openalex.org/W4404800552","https://openalex.org/W4404825031","https://openalex.org/W4405168355","https://openalex.org/W4405559235","https://openalex.org/W4405727682","https://openalex.org/W4406231886","https://openalex.org/W4406758965","https://openalex.org/W4407252588","https://openalex.org/W4408294638","https://openalex.org/W4408605469","https://openalex.org/W4409322793","https://openalex.org/W4410519310","https://openalex.org/W4411154435","https://openalex.org/W4411393176","https://openalex.org/W4412785623","https://openalex.org/W4413286136","https://openalex.org/W4413293314","https://openalex.org/W4413429775","https://openalex.org/W4414166834","https://openalex.org/W4414301026","https://openalex.org/W4415807581","https://openalex.org/W4416121229","https://openalex.org/W4416912163","https://openalex.org/W4416934344","https://openalex.org/W7117724456"],"related_works":["https://openalex.org/W4408605469","https://openalex.org/W4378471342","https://openalex.org/W3150682409","https://openalex.org/W3127407050","https://openalex.org/W7138929343","https://openalex.org/W7223038190","https://openalex.org/W4401327718","https://openalex.org/W3174993170","https://openalex.org/W7115680536","https://openalex.org/W7037508479"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2026-09-06T00:00:00"}