{"id":"https://openalex.org/W7208818356","doi":"https://doi.org/10.1002/age.70197","title":"The Animal Variant Classification Guidelines v2: An Update With New Criteria and Improved Clarifications","display_name":"The Animal Variant Classification Guidelines v2: An Update With New Criteria and Improved Clarifications","publication_year":2026,"publication_date":"2026-09-04","ids":{"openalex":"https://openalex.org/W7208818356","doi":"https://doi.org/10.1002/age.70197","pmid":"https://pubmed.ncbi.nlm.nih.gov/42698066","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13545154"},"language":"en","primary_location":{"id":"doi:10.1002/age.70197","doi":"https://doi.org/10.1002/age.70197","is_oa":true,"landing_page_url":"https://doi.org/10.1002/age.70197","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/age.70197","source":{"id":"https://openalex.org/S12146737","display_name":"Animal Genetics","issn_l":"0268-9146","issn":["0268-9146","1365-2052"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Animal Genetics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/age.70197","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5150216087","display_name":"Lore Desmet","orcid":"https://orcid.org/0009-0005-4550-0820","observed_orcids":["https://orcid.org/0009-0005-4550-0820"]},"institutions":[{"id":"https://openalex.org/I32597200","display_name":"Ghent University","ror":"https://ror.org/00cv9y106","country_code":"BE","type":"education","lineage":["https://openalex.org/I32597200"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Lore Desmet","raw_affiliation_strings":["Center of Clinical Genetics for Companion Animals, Faculty of Veterinary Medicine Ghent University  Merelbeke\u2010Melle Belgium","Laboratory of Animal Genetics, Department of Veterinary and Biosciences, Faculty of Veterinary Medicine Ghent University  Merelbeke\u2010Melle Belgium"],"raw_orcid":"https://orcid.org/0009-0005-4550-0820","affiliations":[{"raw_affiliation_string":"Center of Clinical Genetics for Companion Animals, Faculty of Veterinary Medicine Ghent University  Merelbeke\u2010Melle Belgium","institution_ids":["https://openalex.org/I32597200"]},{"raw_affiliation_string":"Laboratory of Animal Genetics, Department of Veterinary and Biosciences, Faculty of Veterinary Medicine Ghent University  Merelbeke\u2010Melle Belgium","institution_ids":["https://openalex.org/I32597200"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101363255","display_name":"Carlotta Ferrari","orcid":"https://orcid.org/0009-0000-4853-4480","observed_orcids":["https://orcid.org/0009-0000-4853-4480"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Carlotta Ferrari","raw_affiliation_strings":["Department of Veterinary Medicine and Animal Sciences University of Milan  Lodi Italy"],"raw_orcid":"https://orcid.org/0009-0000-4853-4480","affiliations":[{"raw_affiliation_string":"Department of Veterinary Medicine and Animal Sciences University of Milan  Lodi Italy","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007533447","display_name":"Marie Abitbol","orcid":"https://orcid.org/0000-0002-5615-7897","observed_orcids":["https://orcid.org/0000-0002-5615-7897"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210104684","display_name":"VetAgro Sup","ror":"https://ror.org/01c7wz417","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210104684"]},{"id":"https://openalex.org/I4210125101","display_name":"Institut NeuroMyoG\u00e8ne","ror":"https://ror.org/0322sf130","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210096427","https://openalex.org/I4210125101"]},{"id":"https://openalex.org/I4387154458","display_name":"Laboratoire Physiopathologie et G\u00e9n\u00e9tique du Neurone et du Muscle","ror":"https://ror.org/013nhg483","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4387154458"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marie Abitbol","raw_affiliation_strings":["Institut NeuroMyoG\u00e8ne INMG\u2010PGNM, CNRS UMR5261, INSERM U1315, Facult\u00e9 de M\u00e9decine, Rockefeller Universit\u00e9 Claude Bernard Lyon 1  Lyon France","VetAgro Sup Univ. Lyon  Marcy\u2010l'Etoile France"],"raw_orcid":"https://orcid.org/0000-0002-5615-7897","affiliations":[{"raw_affiliation_string":"Institut NeuroMyoG\u00e8ne INMG\u2010PGNM, CNRS UMR5261, INSERM U1315, Facult\u00e9 de M\u00e9decine, Rockefeller Universit\u00e9 Claude Bernard Lyon 1  Lyon France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210125101","https://openalex.org/I4387154458"]},{"raw_affiliation_string":"VetAgro Sup Univ. Lyon  Marcy\u2010l'Etoile France","institution_ids":["https://openalex.org/I4210104684"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037114096","display_name":"Heidi Anderson","orcid":"https://orcid.org/0000-0002-5561-0901","observed_orcids":["https://orcid.org/0000-0002-5561-0901"]},"institutions":[{"id":"https://openalex.org/I32597200","display_name":"Ghent University","ror":"https://ror.org/00cv9y106","country_code":"BE","type":"education","lineage":["https://openalex.org/I32597200"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Heidi Anderson","raw_affiliation_strings":["Laboratory of Animal Genetics, Department of Veterinary and Biosciences, Faculty of Veterinary Medicine Ghent University  Merelbeke\u2010Melle Belgium","Wisdom Panel, Mars Petcare Science & Diagnostics  Fountain Valley California USA"],"raw_orcid":"https://orcid.org/0000-0002-5561-0901","affiliations":[{"raw_affiliation_string":"Laboratory of Animal Genetics, Department of Veterinary and Biosciences, Faculty of Veterinary Medicine Ghent University  Merelbeke\u2010Melle Belgium","institution_ids":["https://openalex.org/I32597200"]},{"raw_affiliation_string":"Wisdom Panel, Mars Petcare Science & Diagnostics  Fountain Valley California USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003998207","display_name":"Danika L. Bannasch","orcid":"https://orcid.org/0000-0002-7614-7207","observed_orcids":["https://orcid.org/0000-0002-7614-7207"]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Danika Bannasch","raw_affiliation_strings":["Department of Population Health and Reproduction University of California Davis School of Veterinary Medicine  Davis California USA"],"raw_orcid":"https://orcid.org/0000-0002-7614-7207","affiliations":[{"raw_affiliation_string":"Department of Population Health and Reproduction University of California Davis School of Veterinary Medicine  Davis California USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052564824","display_name":"Hubert Bauer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086842","display_name":"Laboklin (Germany)","ror":"https://ror.org/002td9r73","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210086842"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hubert Bauer","raw_affiliation_strings":["Laboklin GmbH & Co. KG  Bad Kissingen Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboklin GmbH & Co. KG  Bad Kissingen Germany","institution_ids":["https://openalex.org/I4210086842"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050800724","display_name":"Jerold S. Bell","orcid":"https://orcid.org/0000-0002-7835-6651","observed_orcids":["https://orcid.org/0000-0002-7835-6651"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jerold Bell","raw_affiliation_strings":["Department of Clinical Sciences, Cummings School of Veterinary Medicine Tufts University  North Grafton Massachusetts USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences, Cummings School of Veterinary Medicine Tufts University  North Grafton Massachusetts USA","institution_ids":["https://openalex.org/I121934306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023079016","display_name":"N\u00fcket Bilgen","orcid":"https://orcid.org/0000-0003-2324-7965","observed_orcids":["https://orcid.org/0000-0003-2324-7965"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N\u00fcket Bilgen","raw_affiliation_strings":["GeneControl GmbH  Grub Germany"],"raw_orcid":"https://orcid.org/0000-0003-2324-7965","affiliations":[{"raw_affiliation_string":"GeneControl GmbH  Grub Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073608596","display_name":"Lucie Chevallier","orcid":"https://orcid.org/0000-0001-8602-1993","observed_orcids":["https://orcid.org/0000-0001-8602-1993"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I17606148","display_name":"\u00c9cole Nationale V\u00e9t\u00e9rinaire d'Alfort","ror":"https://ror.org/04k031t90","country_code":"FR","type":"education","lineage":["https://openalex.org/I17606148","https://openalex.org/I197681013","https://openalex.org/I2800365227"]},{"id":"https://openalex.org/I4210159433","display_name":"Institut Mondor de Recherche Biom\u00e9dicale","ror":"https://ror.org/04qe59j94","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I17606148","https://openalex.org/I197681013","https://openalex.org/I2800365227","https://openalex.org/I4210159433"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Lucie Chevallier","raw_affiliation_strings":["U955\u2014IMRB, Team 10\u2014Biology of the Neuromuscular System, Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale Ecole Nationale V\u00e9t\u00e9rinaire d'Alfort  Maisons\u2010Alfort France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"U955\u2014IMRB, Team 10\u2014Biology of the Neuromuscular System, Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale Ecole Nationale V\u00e9t\u00e9rinaire d'Alfort  Maisons\u2010Alfort France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I17606148","https://openalex.org/I4210159433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076341358","display_name":"Caroline Dufaure de Citres","orcid":"https://orcid.org/0000-0001-6968-3864","observed_orcids":["https://orcid.org/0000-0001-6968-3864"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Caroline Dufaure de Citres","raw_affiliation_strings":["Antagene\u2014Animal Genomics Laboratory  La Tour de Salvagny France"],"raw_orcid":"https://orcid.org/0000-0001-6968-3864","affiliations":[{"raw_affiliation_string":"Antagene\u2014Animal Genomics Laboratory  La Tour de Salvagny France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021064201","display_name":"Jonas Donner","orcid":"https://orcid.org/0000-0002-9874-8484","observed_orcids":["https://orcid.org/0000-0002-9874-8484"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jonas Donner","raw_affiliation_strings":["GenomeTails Pet Genetic Counselling and Consulting Services  Espoo Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GenomeTails Pet Genetic Counselling and Consulting Services  Espoo Finland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045863299","display_name":"Carrie J. Finno","orcid":"https://orcid.org/0000-0001-5924-0234","observed_orcids":["https://orcid.org/0000-0001-5924-0234"]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carrie J. Finno","raw_affiliation_strings":["Department of Population Health and Reproduction University of California Davis School of Veterinary Medicine  Davis California USA"],"raw_orcid":"https://orcid.org/0000-0001-5924-0234","affiliations":[{"raw_affiliation_string":"Department of Population Health and Reproduction University of California Davis School of Veterinary Medicine  Davis California USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076203659","display_name":"Guillermo Giovambattista","orcid":"https://orcid.org/0000-0001-8365-3303","observed_orcids":["https://orcid.org/0000-0001-8365-3303"]},"institutions":[{"id":"https://openalex.org/I151201029","display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","ror":"https://ror.org/03cqe8w59","country_code":"AR","type":"government","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210123736","https://openalex.org/I4387155568"]},{"id":"https://openalex.org/I4210164013","display_name":"Instituto de Gen\u00e9tica Veterinaria","ror":"https://ror.org/05fvszr38","country_code":"AR","type":"facility","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210123736","https://openalex.org/I4210138160","https://openalex.org/I4210164013","https://openalex.org/I4387155568","https://openalex.org/I874386039"]},{"id":"https://openalex.org/I874386039","display_name":"Universidad Nacional de La Plata","ror":"https://ror.org/01tjs6929","country_code":"AR","type":"education","lineage":["https://openalex.org/I874386039"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Guillermo Giovambattista","raw_affiliation_strings":["Institute of Veterinary Genetics (IGEVET, UNLP\u2010CONICET), Faculty of Veterinary Sciences National University of La Plata  La Plata Argentina"],"raw_orcid":"https://orcid.org/0000-0001-8365-3303","affiliations":[{"raw_affiliation_string":"Institute of Veterinary Genetics (IGEVET, UNLP\u2010CONICET), Faculty of Veterinary Sciences National University of La Plata  La Plata Argentina","institution_ids":["https://openalex.org/I151201029","https://openalex.org/I4210164013","https://openalex.org/I874386039"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032323740","display_name":"Steven M. Harrison","orcid":"https://orcid.org/0000-0002-9614-9111","observed_orcids":["https://orcid.org/0000-0002-9614-9111"]},"institutions":[{"id":"https://openalex.org/I4210151459","display_name":"Ambry Genetics (United States)","ror":"https://ror.org/051ae8e94","country_code":"US","type":"company","lineage":["https://openalex.org/I4210151459"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven M. Harrison","raw_affiliation_strings":["Ambry Genetics  Aliso Viejo California USA"],"raw_orcid":"https://orcid.org/0000-0002-9614-9111","affiliations":[{"raw_affiliation_string":"Ambry Genetics  Aliso Viejo California USA","institution_ids":["https://openalex.org/I4210151459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070984053","display_name":"Jessica J. Hayward","orcid":"https://orcid.org/0000-0001-6213-5013","observed_orcids":["https://orcid.org/0000-0001-6213-5013"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4210151139","display_name":"New York State College of Veterinary Medicine","ror":"https://ror.org/04r17kf39","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4210151139"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jessica J. Hayward","raw_affiliation_strings":["Department of Biomedical Sciences and Cornell Veterinary Biobank, College of Veterinary Medicine Cornell University  Ithaca New York USA"],"raw_orcid":"https://orcid.org/0000-0001-6213-5013","affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences and Cornell Veterinary Biobank, College of Veterinary Medicine Cornell University  Ithaca New York USA","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4210151139"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017353709","display_name":"Jens U. H\u00e4ggstr\u00f6m","orcid":"https://orcid.org/0000-0003-3402-023X","observed_orcids":["https://orcid.org/0000-0003-3402-023X"]},"institutions":[{"id":"https://openalex.org/I298625061","display_name":"Swedish University of Agricultural Sciences","ror":"https://ror.org/02yy8x990","country_code":"SE","type":"education","lineage":["https://openalex.org/I298625061"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Jens H\u00e4ggstr\u00f6m","raw_affiliation_strings":["Department of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science Swedish University of Agricultural Sciences  Uppsala Sweden"],"raw_orcid":"https://orcid.org/0000-0003-3402-023X","affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science Swedish University of Agricultural Sciences  Uppsala Sweden","institution_ids":["https://openalex.org/I298625061"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016328395","display_name":"Jason T. Huff","orcid":"https://orcid.org/0000-0002-0088-1640","observed_orcids":["https://orcid.org/0000-0002-0088-1640"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jason T. Huff","raw_affiliation_strings":["Wisdom Panel, Mars Petcare Science & Diagnostics  Fountain Valley California USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wisdom Panel, Mars Petcare Science & Diagnostics  Fountain Valley California USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029969915","display_name":"Tosso Leeb","orcid":"https://orcid.org/0000-0003-0553-4880","observed_orcids":["https://orcid.org/0000-0003-0553-4880"]},"institutions":[{"id":"https://openalex.org/I118564535","display_name":"University of Bern","ror":"https://ror.org/02k7v4d05","country_code":"CH","type":"education","lineage":["https://openalex.org/I118564535"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Tosso Leeb","raw_affiliation_strings":["Institute of Genetics, Vetsuisse Faculty University of Bern  Bern Switzerland"],"raw_orcid":"https://orcid.org/0000-0003-0553-4880","affiliations":[{"raw_affiliation_string":"Institute of Genetics, Vetsuisse Faculty University of Bern  Bern Switzerland","institution_ids":["https://openalex.org/I118564535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040552494","display_name":"Ingrid Ljungvall","orcid":"https://orcid.org/0000-0002-6617-0454","observed_orcids":["https://orcid.org/0000-0002-6617-0454"]},"institutions":[{"id":"https://openalex.org/I298625061","display_name":"Swedish University of Agricultural Sciences","ror":"https://ror.org/02yy8x990","country_code":"SE","type":"education","lineage":["https://openalex.org/I298625061"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Ingrid Ljungvall","raw_affiliation_strings":["Department of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science Swedish University of Agricultural Sciences  Uppsala Sweden"],"raw_orcid":"https://orcid.org/0000-0002-6617-0454","affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science Swedish University of Agricultural Sciences  Uppsala Sweden","institution_ids":["https://openalex.org/I298625061"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083773618","display_name":"M. Longeri","orcid":"https://orcid.org/0000-0001-7863-1855","observed_orcids":["https://orcid.org/0000-0001-7863-1855"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maria Longeri","raw_affiliation_strings":["Department of Veterinary Medicine and Animal Sciences University of Milan  Lodi Italy"],"raw_orcid":"https://orcid.org/0000-0001-7863-1855","affiliations":[{"raw_affiliation_string":"Department of Veterinary Medicine and Animal Sciences University of Milan  Lodi Italy","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088795366","display_name":"Leslie A. Lyons","orcid":"https://orcid.org/0000-0002-1628-7726","observed_orcids":["https://orcid.org/0000-0002-1628-7726"]},"institutions":[{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leslie A. Lyons","raw_affiliation_strings":["Department of Veterinary Medicine and Surgery, College of Veterinary Medicine University of Missouri  Columbia Missouri USA"],"raw_orcid":"https://orcid.org/0000-0002-1628-7726","affiliations":[{"raw_affiliation_string":"Department of Veterinary Medicine and Surgery, College of Veterinary Medicine University of Missouri  Columbia Missouri USA","institution_ids":["https://openalex.org/I76835614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056872949","display_name":"M. Martinez","orcid":"https://orcid.org/0000-0002-4666-2910","observed_orcids":["https://orcid.org/0000-0002-4666-2910"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marcela Martinez","raw_affiliation_strings":["Applied Genetics Laboratory Sociedad Rural Argentina  Buenos Aires Argentina"],"raw_orcid":"https://orcid.org/0000-0002-4666-2910","affiliations":[{"raw_affiliation_string":"Applied Genetics Laboratory Sociedad Rural Argentina  Buenos Aires Argentina","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081540003","display_name":"Cathryn S. Mellersh","orcid":"https://orcid.org/0000-0002-2336-0370","observed_orcids":["https://orcid.org/0000-0002-2336-0370"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Cathryn Mellersh","raw_affiliation_strings":["Department of Veterinary Medicine, Canine Genetics Centre University of Cambridge  Cambridge UK"],"raw_orcid":"https://orcid.org/0000-0002-2336-0370","affiliations":[{"raw_affiliation_string":"Department of Veterinary Medicine, Canine Genetics Centre University of Cambridge  Cambridge UK","institution_ids":["https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053230157","display_name":"Frank W. Nicholas","orcid":"https://orcid.org/0000-0002-9178-3965","observed_orcids":["https://orcid.org/0000-0002-9178-3965"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Frank W. Nicholas","raw_affiliation_strings":["Sydney School of Veterinary Science, Faculty of Science The University of Sydney  Sydney Australia"],"raw_orcid":"https://orcid.org/0000-0002-9178-3965","affiliations":[{"raw_affiliation_string":"Sydney School of Veterinary Science, Faculty of Science The University of Sydney  Sydney Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040861878","display_name":"\u00c5sa Ohlsson","orcid":"https://orcid.org/0000-0003-1116-0141","observed_orcids":["https://orcid.org/0000-0003-1116-0141"]},"institutions":[{"id":"https://openalex.org/I298625061","display_name":"Swedish University of Agricultural Sciences","ror":"https://ror.org/02yy8x990","country_code":"SE","type":"education","lineage":["https://openalex.org/I298625061"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"\u00c5sa Ohlsson","raw_affiliation_strings":["Department of Animal Biosciences, Faculty of Veterinary Medicine and Animal Science Swedish University of Agricultural Sciences  Uppsala Sweden"],"raw_orcid":"https://orcid.org/0000-0003-1116-0141","affiliations":[{"raw_affiliation_string":"Department of Animal Biosciences, Faculty of Veterinary Medicine and Animal Science Swedish University of Agricultural Sciences  Uppsala Sweden","institution_ids":["https://openalex.org/I298625061"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077134544","display_name":"Jessica L. Petersen","orcid":"https://orcid.org/0000-0001-5438-8555","observed_orcids":["https://orcid.org/0000-0001-5438-8555"]},"institutions":[{"id":"https://openalex.org/I114395901","display_name":"University of Nebraska\u2013Lincoln","ror":"https://ror.org/043mer456","country_code":"US","type":"education","lineage":["https://openalex.org/I114395901"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jessica L. Petersen","raw_affiliation_strings":["Department of Animal Science University of Nebraska\u2010Lincoln  Lincoln Nebraska USA"],"raw_orcid":"https://orcid.org/0000-0001-5438-8555","affiliations":[{"raw_affiliation_string":"Department of Animal Science University of Nebraska\u2010Lincoln  Lincoln Nebraska USA","institution_ids":["https://openalex.org/I114395901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061070537","display_name":"Pascale M. Y. Smets","orcid":"https://orcid.org/0000-0002-9375-2599","observed_orcids":["https://orcid.org/0000-0002-9375-2599"]},"institutions":[{"id":"https://openalex.org/I32597200","display_name":"Ghent University","ror":"https://ror.org/00cv9y106","country_code":"BE","type":"education","lineage":["https://openalex.org/I32597200"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Pascale Smets","raw_affiliation_strings":["Small Animal Department, Faculty of Veterinary Medicine Ghent University  Merelbeke\u2010Melle Belgium"],"raw_orcid":"https://orcid.org/0000-0002-9375-2599","affiliations":[{"raw_affiliation_string":"Small Animal Department, Faculty of Veterinary Medicine Ghent University  Merelbeke\u2010Melle Belgium","institution_ids":["https://openalex.org/I32597200"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138054944","display_name":"Maria G. Strillacci","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maria G. Strillacci","raw_affiliation_strings":["Department of Veterinary Medicine and Animal Sciences University of Milan  Lodi Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Medicine and Animal Sciences University of Milan  Lodi Italy","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064843221","display_name":"Imke Tammen","orcid":"https://orcid.org/0000-0002-5520-6597","observed_orcids":["https://orcid.org/0000-0002-5520-6597"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Imke Tammen","raw_affiliation_strings":["Sydney School of Veterinary Science, Faculty of Science The University of Sydney  Camden Australia"],"raw_orcid":"https://orcid.org/0000-0002-5520-6597","affiliations":[{"raw_affiliation_string":"Sydney School of Veterinary Science, Faculty of Science The University of Sydney  Camden Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055531381","display_name":"Samantha L. Van Buren","orcid":"https://orcid.org/0000-0003-1399-9637","observed_orcids":["https://orcid.org/0000-0003-1399-9637"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Samantha Van Buren","raw_affiliation_strings":["Orivet Genetic Pet Care  Knoxville Tennessee USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orivet Genetic Pet Care  Knoxville Tennessee USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006203141","display_name":"Frank G. van Steenbeek","orcid":"https://orcid.org/0000-0001-5460-6540","observed_orcids":["https://orcid.org/0000-0001-5460-6540"]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Frank G. van Steenbeek","raw_affiliation_strings":["Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University  Utrecht the Netherlands"],"raw_orcid":"https://orcid.org/0000-0001-5460-6540","affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences, Faculty of Veterinary Medicine Utrecht University  Utrecht the Netherlands","institution_ids":["https://openalex.org/I193662353"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027172579","display_name":"Bart J. G. Broeckx","orcid":"https://orcid.org/0000-0001-6742-3911","observed_orcids":["https://orcid.org/0000-0001-6742-3911"]},"institutions":[{"id":"https://openalex.org/I32597200","display_name":"Ghent University","ror":"https://ror.org/00cv9y106","country_code":"BE","type":"education","lineage":["https://openalex.org/I32597200"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Bart J. G. Broeckx","raw_affiliation_strings":["Center of Clinical Genetics for Companion Animals, Faculty of Veterinary Medicine Ghent University  Merelbeke\u2010Melle Belgium","Laboratory of Animal Genetics, Department of Veterinary and Biosciences, Faculty of Veterinary Medicine Ghent University  Merelbeke\u2010Melle Belgium"],"raw_orcid":"https://orcid.org/0000-0001-6742-3911","affiliations":[{"raw_affiliation_string":"Center of Clinical Genetics for Companion Animals, Faculty of Veterinary Medicine Ghent University  Merelbeke\u2010Melle Belgium","institution_ids":["https://openalex.org/I32597200"]},{"raw_affiliation_string":"Laboratory of Animal Genetics, Department of Veterinary and Biosciences, Faculty of Veterinary Medicine Ghent University  Merelbeke\u2010Melle Belgium","institution_ids":["https://openalex.org/I32597200"]}]}],"institutions":[],"countries_distinct_count":11,"institutions_distinct_count":26,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3570,"currency":"USD","value_usd":3570},"apc_paid":null,"fwci":3.9268,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.94655486,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"57","issue":"5","first_page":"e70197","last_page":"e70197"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/variant-pathogenicity-classification","display_name":"variant pathogenicity classification","score":0.7820000052452087},{"id":"https://openalex.org/keywords/pathogenic-variants","display_name":"pathogenic variants","score":0.8970000147819519},{"id":"https://openalex.org/keywords/benign-variants","display_name":"benign variants","score":0.550000011920929},{"id":"https://openalex.org/keywords/variant-classification-criteria","display_name":"variant classification criteria","score":0.628000020980835},{"id":"https://openalex.org/keywords/variant-pathogenicity-assessment","display_name":"variant pathogenicity assessment","score":0.4300000071525574}],"concepts":[{"id":"https://openalex.org/C64502627","wikidata":"https://www.wikidata.org/wiki/Q170065","display_name":"Pathogenicity","level":2,"score":0.7495999932289124},{"id":"https://openalex.org/C188087704","wikidata":"https://www.wikidata.org/wiki/Q369577","display_name":"Standardization","level":2,"score":0.6370000243186951},{"id":"https://openalex.org/C175783326","wikidata":"https://www.wikidata.org/wiki/Q185055","display_name":"Mendelian inheritance","level":3,"score":0.5626000165939331},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5374000072479248},{"id":"https://openalex.org/C2778012447","wikidata":"https://www.wikidata.org/wiki/Q1034415","display_name":"Scope (computer science)","level":2,"score":0.53329998254776},{"id":"https://openalex.org/C191791410","wikidata":"https://www.wikidata.org/wiki/Q241953","display_name":"OMIM : Online Mendelian Inheritance in Man","level":4,"score":0.4805000126361847},{"id":"https://openalex.org/C2780902518","wikidata":"https://www.wikidata.org/wiki/Q6033780","display_name":"Inheritance (genetic algorithm)","level":3,"score":0.4699000120162964},{"id":"https://openalex.org/C2780673598","wikidata":"https://www.wikidata.org/wiki/Q285223","display_name":"Genetic testing","level":2,"score":0.4415000081062317},{"id":"https://openalex.org/C64474127","wikidata":"https://www.wikidata.org/wiki/Q1071953","display_name":"Medical genetics","level":3,"score":0.3813000023365021},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.33640000224113464},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3353999853134155},{"id":"https://openalex.org/C2993967602","wikidata":"https://www.wikidata.org/wiki/Q5532932","display_name":"Genetic variants","level":4,"score":0.30809998512268066},{"id":"https://openalex.org/C2778117688","wikidata":"https://www.wikidata.org/wiki/Q264024","display_name":"Animal model","level":2,"score":0.2955999970436096},{"id":"https://openalex.org/C2991862235","wikidata":"https://www.wikidata.org/wiki/Q170201","display_name":"Animal health","level":2,"score":0.2531000077724457}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005820","descriptor_name":"Genetic Testing","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D005820","descriptor_name":"Genetic Testing","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017408","descriptor_name":"Guidelines as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1002/age.70197","doi":"https://doi.org/10.1002/age.70197","is_oa":true,"landing_page_url":"https://doi.org/10.1002/age.70197","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/age.70197","source":{"id":"https://openalex.org/S12146737","display_name":"Animal Genetics","issn_l":"0268-9146","issn":["0268-9146","1365-2052"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Animal Genetics","raw_type":"journal-article"},{"id":"pmid:42698066","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42698066","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Animal genetics","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13545154","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13545154/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13545154/pdf/AGE-57-0.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Anim Genet","raw_type":"Text"},{"id":"pmh:oai:archive.ugent.be:01M1XETTGDZTK5VNPHD1JZS0Q6","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1854/LU-01M1XETTGDZTK5VNPHD1JZS0Q6","pdf_url":null,"source":{"id":"https://openalex.org/S4306400478","display_name":"Ghent University Academic Bibliography (Ghent University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I32597200","host_organization_name":"Ghent University","host_organization_lineage":["https://openalex.org/I32597200"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 1365-2052","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:dspace.library.uu.nl:1874/490802","doi":null,"is_oa":false,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/490802","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"doi:10.48620/100926","doi":"https://doi.org/10.48620/100926","is_oa":true,"landing_page_url":"https://doi.org/10.48620/100926","pdf_url":null,"source":{"id":"https://openalex.org/S7407053152","display_name":"Open Access CRIS of the University of Bern","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.1002/age.70197","doi":"https://doi.org/10.1002/age.70197","is_oa":true,"landing_page_url":"https://doi.org/10.1002/age.70197","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/age.70197","source":{"id":"https://openalex.org/S12146737","display_name":"Animal Genetics","issn_l":"0268-9146","issn":["0268-9146","1365-2052"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Animal Genetics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8048999905586243,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321996","display_name":"Royal Canin","ror":"https://ror.org/01b1e4b88"},{"id":"https://openalex.org/F4320322603","display_name":"Universiteit Gent","ror":"https://ror.org/00cv9y106"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7208818356.pdf","grobid_xml":"https://content.openalex.org/works/W7208818356.grobid-xml"},"referenced_works_count":9,"referenced_works":["https://openalex.org/W2051978340","https://openalex.org/W4405030782","https://openalex.org/W4408026037","https://openalex.org/W4409729926","https://openalex.org/W4410998153","https://openalex.org/W4412068299","https://openalex.org/W4415226871","https://openalex.org/W4416337489","https://openalex.org/W4416731666"],"related_works":["https://openalex.org/W4405030782","https://openalex.org/W4416337489","https://openalex.org/W4402589652","https://openalex.org/W3175363840","https://openalex.org/W2612091911","https://openalex.org/W3215640949","https://openalex.org/W4324117526","https://openalex.org/W2969908248","https://openalex.org/W7203890471","https://openalex.org/W4392589429"],"abstract_inverted_index":{"The":[0,58,143,164],"Animal":[1,109,127,186],"Variant":[2,101],"Classification":[3],"Guidelines":[4],"(AVCG)":[5],"were":[6,56,83,169],"developed":[7,170],"to":[8,26,66,85,197],"standardize":[9],"and":[10,23,30,52,74,167,179,192],"objectify":[11],"the":[12,37,88,91,100,108,123,131,135,153,172,175,180,185,199],"classification":[13],"of":[14,60,90,107,119,122,133,156,174,203],"putative":[15,140,204],"disease-causing":[16,32,141,205],"variants.":[17,142,206],"These":[18,93],"guidelines":[19,38,95],"are":[20,24,39,96],"sufficiently":[21],"reproducible":[22],"used":[25,98],"classify":[27],"previously":[28],"published":[29,139],"new":[31,50,70,76],"variants":[33,82],"across":[34],"species.":[35],"Here,":[36],"updated":[40,94],"(AVCG.v2),":[41],"based":[42],"on":[43],"a":[44,117,147],"three-phase":[45],"decision":[46],"process.":[47],"Overall,":[48],"four":[49],"criteria":[51,61,71,166],"seven":[53],"clarifying":[54],"comments":[55],"added.":[57],"number":[59],"has":[62],"increased":[63],"from":[64],"23":[65],"27,":[67],"with":[68],"three":[69],"supporting":[72,78,201],"pathogenicity":[73,144,202],"one":[75],"criterion":[77],"benign":[79],"classification.":[80],"Pharmacogenomic":[81],"determined":[84],"fall":[86],"within":[87],"scope":[89],"guidelines.":[92],"being":[97],"by":[99,171],"Pathogenicity":[102],"Working":[103],"Group":[104],"(VPWG),":[105],"part":[106],"Genetic":[110],"Testing":[111,188],"Standardization":[112,189],"standing":[113],"committee,":[114],"which":[115],"is":[116],"committee":[118],"elected":[120],"members":[121],"International":[124],"Society":[125],"for":[126,146],"Genetics":[128,187],"(ISAG).":[129],"Under":[130],"auspices":[132],"ISAG,":[134],"VPWG":[136],"retrospectively":[137],"classifies":[138],"label":[145],"variant":[148,154],"will":[149],"be":[150],"presented":[151],"in":[152,160],"tables":[155],"Online":[157],"Mendelian":[158],"Inheritance":[159],"Animals":[161],"(OMIA;":[162],"https://omia.org/).":[163],"AVCGv.2":[165],"recommendations":[168],"expertise":[173],"animal":[176],"genetics":[177],"community":[178],"ISAG":[181],"Executive":[182],"Committee":[183,190],"through":[184],"endorses":[191],"strongly":[193],"encourages":[194],"their":[195],"use":[196],"evaluate":[198],"evidence":[200]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2026-09-06T00:00:00"}